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  1. 39541

    Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

    Published 2025-02-01
    “…The ability to assay ORF2p directly and quantitatively will improve our understanding of the developmental and diseased cell states where L1 expression and its activity naturally occur. The ability to simultaneously assay endogenous L1 ORF1p and ORF2p is an important step forward for L1 analytical biochemistry. …”
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  2. 39542

    Mathematical Modelling and Analysis of Transmission Dynamics of Lassa Fever by E. A. Bakare, E. B. Are, O. E. Abolarin, S. A. Osanyinlusi, Benitho Ngwu, Obiaderi N. Ubaka

    Published 2020-01-01
    “…Deaths from Lassa fever occur all year round but naturally peak during the dry season. Annually, the number of people infected is estimated at 100,000 to 300,000, with approximately 5,000 deaths. …”
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  3. 39543

    A Semianalytical Model for Analyzing the Infill Well-Caused Fracture Interference from Shale Gas Reservoirs by Sidong Fang, Yonghui Wu, Cheng Dai, Liqiang Ma, Hua Liu

    Published 2021-01-01
    “…In this way, three important issues can be further handled very naturally, including fracture connection between the parent and infill wells, different SRV properties for zones with different distances to the wellbore, and different production times for adjacent wellbores. …”
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  4. 39544
  5. 39545

    Comparative Analysis of Tenogenic Gene Expression in Tenocyte-Derived Induced Pluripotent Stem Cells and Bone Marrow-Derived Mesenchymal Stem Cells in Response to Biochemical and B... by Feikun Yang, Dean W. Richardson

    Published 2021-01-01
    “…The tendon is highly prone to injury, overuse, or age-related degeneration in both humans and horses. Natural healing of injured tendon is poor, and cell-based therapeutic treatment is still a significant clinical challenge. …”
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  6. 39546

    Phytochemical investigation and assessment of the anti-inflammatory activity of four Heracleum taxa growing in Turkey by Ekin Kurtul, Esra Küpeli Akkol, Büşra Karpuz Ağören, Büşra Yaylacı, Özlem Bahadır Acıkara, Eduardo Sobarzo-Sánchez, Eduardo Sobarzo-Sánchez

    Published 2025-01-01
    “…The Heracleum genus is also prominently recognized for its high content of coumarins, which are considered a significant group of natural compounds known for their noteworthy anti-inflammatory properties.MethodsThe present study evaluated the anti-inflammatory activity of dichloromethane and methanolic extracts from H. paphlagonicum, H. sphondylium subsp. ternatum, H. sphondylium subsp. elegans, and H. sphondylium subsp. cyclocarpum (100 mg/kg), which have not been previously investigated for their anti-inflammatory properties. …”
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  7. 39547

    Contralateral Posterior Chamber Phakic Intraocular Lens Implantation as Rehabilitation of Refractive Lens Exchange with a Monofocal Intraocular Lens in a Young, Nonpresbyopic, Bila... by Kepa Balparda, Claudia Marcela Vanegas-Ramírez, Laura Segura-Muñoz, Manuela Gómez-Londoño

    Published 2019-01-01
    “…On the other hand, implantation of a P-IOL is a good option if eye conditions are optimal, as it preserves natural accommodation. In this case an EyeCryl Phakic Toric® IOL showed excellent short-term refractive predictability and safety.…”
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  8. 39548

    Assessment of synergistic efficacy of carbaryl in combination with Cinnamomum cassia and Origanum vulgare essential oils against Dermanyssus gallinae by Zhonghao Wang, Kai Xu, Shuo Yin, Jing Liu, Jianhua Qin, Dehe Wang, Lijun Xu, Chuanwen Wang

    Published 2025-01-01
    “…Therefore, plant essential oils (EOs), which exhibit natural acaricidal properties and environmental compatibility, represent promising candidates for developing eco-friendly acaricides. …”
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  9. 39549

    Assessment of Soil Erosion and Its Impact on Agricultural Productivity by Using the RMMF Model and Local Perception: A Case Study of Rangun Watershed of Mid-Hills, Nepal by Dinesh Bhandari, Rajeev Joshi, Raju Raj Regmi, Nripesh Awasthi

    Published 2021-01-01
    “…Soil erosion is a major concern for the environment and natural resources leading to a serious threat to agricultural productivity and one of the major causes of land degradation in the mid-hills region of Nepal. …”
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  10. 39550

    Genetic variability and population structure analysis of Protostrongylus oryctolagi (Nematoda: Protostrongylidae) in Lepus europaeus from Central and Northern Italy. by Ilaria Guarniero, Laura Stancampiano, Rafaella Franch, Elisa Armaroli, Fabio Macchioni, Enrico Negrisolo

    Published 2025-01-01
    “…The observed data may be explained by several factors ranging from the parasite's biology (presence of a narrow host spectrum), the final host's behaviour (small home range), the natural dispersion of the host-parasite dyad occurred in past or the recent passive men-mediated migration. …”
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  11. 39551

    Modulating the anti-inflammatory and barrier protective effects on intestinal epithelial cells utilizing an aqueous Aspalathus linearis extract in vitro by Shana De Bruyn-Orr, Stefan Abel, Mariam Rado, Mariska Lilly

    Published 2025-02-01
    “…Background: Rooibos is a natural herbal plant containing numerous unique polyphenols which have been associated with certain health benefits. …”
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  12. 39552

    Inteligencia artificial en la industria de la hospitalidad latinoamericana: una revisión de alcance by Ismael Castillo-Ortiz, Elizabeth Guevara Martínez, Carmen Villar-Patiño

    Published 2025-01-01
    “…Además, se encontró que las técnicas de inteligencia artificial más empleadas en el sector de la hospitalidad son aprendizaje de máquina y procesamiento de lenguaje natural. Sin embargo, se detectó que las investigaciones sobre esta temática en los países latinoamericanos representan menos del 3,5% de la producción global. …”
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  13. 39553

    Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects by Ada Alice Dona, Theophilus Tandoh, Lokesh Nigam, Mahmoud Singer, Enrico Caserta, Mariam Murtadha, Yinghui Zhu, Milad Moloudizargari, Preeti Sharma, Ottavio Napolitano, Janet Winchester, Arnab Chowdhury, Alex Pozhitkov, James F. Sanchez, Hawa Vahed, Guido Marcucci, Matt Coffey, Gerard Nuovo, Douglas W. Sborov, Flavia Pichiorri, Craig C Hofmeister

    Published 2025-01-01
    “…Abstract Background Reovirus (RV) is an oncolytic virus with natural tropism for cancer cells. We previously showed that RV administration in multiple myeloma (MM) patients was safe, but disease control associated with viral replication in the cancer cells was not observed. …”
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  14. 39554

    NEOPOSITIVISMO Y CONOCIMIENTO REGIONAL: LA HISTORIA DE UNA FRUSTRACIÓN by Gerardo M. de Jong

    Published 2003-12-01
    “…Esta explicación comprehensiva del espacio regional requiere del trabajo interdisciplinario en estrecho contacto con otras ciencias sociales (especialmente economistas y sociólogos) y con las disciplinas que tienen capacidad de producir conocimiento sintético acerca del comportamiento del medio natural. En este sentido, es necesario construir una crítica de los aportes de algunos de los estudiosos, de vertiente neopositivista, que se ocuparon del comportamiento del espacio regional.…”
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  15. 39555

    Evaluating Dispersion of Residential CO and NOx Emissions with the Help of Different Models in Körfez District, Kocaeli Province by Kazım Demirarslan, Şenay Çetin Doğruparmak

    Published 2015-07-01
    “…The residential area is 5.31 km2 and natural gas, fuel-oil, wood, and coal are used as heating fuels in this district. …”
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  16. 39556

    Plasmid-free production of the plant lignan pinoresinol in growing Escherichia coli cells by U. Joost Luelf, Alexander Wassing, Lisa M. Böhmer, Vlada B. Urlacher

    Published 2024-10-01
    “…As (-)-podophyllotoxin is traditionally isolated from endangered and therefore limited natural sources, there is a particular need for biotechnological production. …”
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  17. 39557

    ANTHROPOLOGICAL SPHERE OF HUMAN EXISTENCE: RESTRICTIONS ON HUMAN RIGHTS DURING PANDEMIC THREATS by V. S. Blikhar, I. M. Zharovska

    Published 2020-12-01
    “…Today, international guiding principles on human rights response to global natural threats have been updated. However, there are still no specific legal recommendations (both at the international and national levels) concerning measures on human rights protection during outbreaks of various infectious diseases. …”
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  18. 39558

    The regulatory effects of (p)ppGpp and indole on cAMP synthesis in <i>Escherichia coli</i> cells by N. M. Kashevarova, E. A. Khaova, A. G. Tkachenko

    Published 2024-03-01
    “…The mutual influence of network signaling molecules represented by cells’ natural metabolites, including indole and second messengers (p)ppGpp and cAMP, is hitherto not well understood, being the aim of this study. …”
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  19. 39559

    A century of Azolla filiculoides biocontrol: the economic value of Stenopelmus rufinasus to Great Britain by Corin F. Pratt, Kate Constantine, Suzy V. Wood

    Published 2022-11-01
    “…Abstract Background The invasive aquatic fern Azolla filiculoides has been present in Great Britain (GB) since the end of the nineteenth century, while its specialist natural enemy, the weevil Stenopelmus rufinasus was first recorded nearly four decades later, in 1921. …”
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  20. 39560

    Analysis of the behaviour of the Tukad Buluk Poh flood water at the Gilimanuk - Denpasar National Road Crossing by Hidayat Acep, Suprapti, Isradi Muhammad, Dwi Praptoyo Riska

    Published 2025-01-01
    “…In most of Indonesia, floods are a common natural disaster that spreads into several watersheds during the rainy season. …”
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