Bioinformatics and Deep Learning Approach to Discover Food-Derived Active Ingredients for Alzheimer’s Disease Therapy by Junyu Zhou, Chen Li, Yong Kwan Kim, Sunmin Park

“…This study aimed to identify natural compounds (NCs) with therapeutic potential in AD using an innovative bioinformatics-integrated deep neural analysis approach, combining computational predictions with molecular docking and in vitro experiments for comprehensive evaluation. …”
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Scopoletin as a cardioprotective agent against cisplatin-induced oxidative stress and inflammation by Esam Qnais, Omar Gammoh, Yousra Bsieso, Mohammad Alqudah, Mohammad Wedyan, Sara Altaber, Alaa A.A. Aljabali, Abdelrahim Alqudah, Taher Hatahet

“…Background: Cisplatin (CP) is a chemotherapeutic agent notorious for its cardiotoxic effects. Scopoletin, a natural coumarin, has shown potential due to its antioxidant, anti-inflammatory, and anti-apoptotic properties, which may counteract CP-induced cardiotoxicity. …”
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Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population by Iryna Kril, Iryna Kril, Andrzej Wiśniewski, Agnieszka Tarnowska, Khrystyna Lishchuk-Yakymovych, Yaryna Bojko, Piotr Kuśnierczyk, Valentyna V. Chopyak, Izabela Nowak

“…These molecules present antigenic peptides to CD8+ T lymphocytes and natural killer cells. HLA-I molecules bind their peptide cargo (8–10 amino acids long) in the endoplasmic reticulum. …”
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Estudo Comparativo dos Efeitos da Corrosão Acelerada em Concretos Convencionais e em Concretos com Agregados Reciclados by Luiz Felipe Brioschi Caliman, Vítor Roberto Martins Pereira Souza, Pedro Valle Salles, Érika Márcia Assis de Souza, Italo Matos Gomide, Hélio Augusto Goulart Diniz

“…As massas especifica e unitária do agregado reciclado apresentaram valores menores, porém a absorção de água foi, aproximadamente, 47 vezes maior que a do agregado natural. Obtidas as características, foi possível determinar o traço a ser utilizado conforme o método de dosagem ABCP/ACI. …”
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Attitudes Toward General Vaccination Mediate the Association Between Influenza Vaccination History and Pneumococcal Vaccination Intention Among Older Adults in China by Siwen Huang, Chi Ruan, Yan Jiang, Yudan Song, Yuhang Zhang, Zeying Qin, Xinyu Shi, Mengyue Zhang, Jingtao Zhou, Dingwan Chen, Yongkang Xiao, Liang Wang, Lili Tian, Rui Peng, Zongchao Peng, Sitong Luo

“…In contrast, negative attitudes toward general vaccination, including mistrust of vaccine benefits (r = −0.253, <i>p</i> < 0.001), worries about unforeseen future effects (r = −0.180, <i>p</i> < 0.001), concerns about commercial profiteering (r = −0.360, <i>p</i> < 0.001), and a preference for natural immunity (r = −0.212, <i>p</i> < 0.001) were negatively associated with pneumococcal vaccination intention. …”
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Predictors for abundance of host flea and floor flea in households of villages with endemic commensal rodent plague, Yunnan Province, China. by Jia-Xiang Yin, Alan Geater, Virasakdi Chongsuvivatwong, Xing-Qi Dong, Chun-Hong Du, You-Hong Zhong

“…<h4>Background</h4>From 1990 to 2006, fifty-five natural villages experienced at least one plague epidemic in Lianghe County, Yunnan Province, China. …”
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Denture use and a slower rate of cognitive decline among older adults with partial tooth loss in China: A 10‐year prospective cohort study by Xiang Qi, Zheng Zhu, Yaolin Pei, Bei Wu

“…Methods We analyzed data from the Chinese Longitudinal Healthy Longevity Survey 2008–2018, including 27,708 community‐dwelling dentate and edentulous (i.e., who have lost all natural teeth) older adults aged 65 and older. Cognitive function was assessed using the Mini‐Mental State Examination from 2008 to 2018. …”
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Comparative Analysis of Utility and Efficacy of Ozone Therapy versus Laser Therapy in Periarthritis Shoulder by Sunil Kumar, Harish Kumar, Prashant Pratap Singh, Dinesh Kumar, Vyutpanna Mishra, Ishan Ahmad

“…It is considered a self-limiting condition with a natural history of 1–3 years while some have refractory course. …”
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Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity by Roel A. van der Heijden, Martine C. Morrison, Fareeba Sheedfar, Petra Mulder, Marijke Schreurs, Pascal P. H. Hommelberg, Marten H. Hofker, Casper Schalkwijk, Robert Kleemann, Uwe J. F. Tietge, Debby P. Y. Koonen, Peter Heeringa

“…Background. Naturally occurring substances from the flavanol and anthocyanin family of polyphenols have been proposed to exert beneficial effects in the course of obesity. …”
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Riesgo cardiovascular en mujeres sanas by Mildrey Jiménez López, Carlos Jorge Hidalgo Mesa, Ivonne Cepero Rodríguez, Sarait Rojas Hernández, Niurka Milagros Ortiz Madrazo

“…Presentan alta morbilidad y mortalidad en mujeres de entre 40 y 59 años, período que coincide con la menopausia natural. Objetivo: Caracterizar el riesgo cardiovascular en pacientes femeninas sanas. …”
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Sybil-Resistant Self-Sovereign Identity Utilizing Attested Execution Secure Processors and Zero-Knowledge Membership Proofs by Koichi Moriyama, Akira Otsuka

“…SSI brings various benefits to natural persons, such as owning controls; conversely, digital identity systems in the real world require Sybil-resistance to comply with anti-money laundering (AML) and other needs. …”
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Influence of Blanching Time on the Phytochemical and Nutritive Value of Cowpea (Vigna unguiculata L. Walp) Leafy Vegetable by M. Y. Maila, P. E. Tseke

“…To reduce the bacterial content and inactivate the naturally occurring enzymes that could induce undesirable changes during storage of the vegetable, blanching is applied. …”
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Map Floodwater Radar Imagery using Machine Learning Algorithms by Thanh-Nghi Doan, Duc-Ngoc Le-Thi

“… Flooding is a widespread and costly natural disaster around the world. Accurately assessing the extent of flooding in near real-time is crucial for governments and humanitarian organizations. …”
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Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3. by Chrissy H Roberts, Sandra Molina, Pateh Makalo, Hassan Joof, Emma M Harding-Esch, Sarah E Burr, David C W Mabey, Robin L Bailey, Matthew J Burton, Martin J Holland

“…The polymorphic Killer-cell Immunoglobulin-like Receptors (KIR) are found on Natural Killer cells and have co-evolved with the Human Leucocyte Antigen (HLA) class I system. …”
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Research on the robustness of convolutional neural networks in image recognition by Dian LIN, Li PAN, Ping YI

“…Convolutional neural network is one of the key technologies in the application of image recognition and processing in artificial intelligence.Its wide application makes researches on its robustness more and more important.Previous researches on robustness of neural networks were too sweeping and most of them focused on adversarial robustness, which causes difficulty in further study in the mechanism of neural network robustness.The related researches of neuroscience were introduced and the concept of visual robustness was put forward.By studying the similarity and difference between neural network models and human visual system, the internal mechanism and faults of neural network robustness were revealed.The researches of neural network robustness in recent years were reviewed, and the reasons for the lack of robustness of neural network models were analyzed.The lack of robustness of neural networks is reflected in their sensitivity to small perturbations.The reason is that neural networks tend to learn high-frequency information for calculation and inference, which is difficult for humans to recognize.High-frequency information is easily affected by perturbations, and eventually causes mistakes of models.Previous researches on robustness mostly focused on mathematical properties of models, and were limited in the natural faults of neural networks.Visual robustness extends the traditional concept of robustness.The traditional concept of robustness measures the discrimination ability of models for distorted image examples.Distorted examples and clean examples can get correct outputs through robust models.Visual robustness measures the consistency between models and humans in discrimination ability.Visual robustness combines the research methods and achievements of neuroscience and psychology with artificial intelligence.The development of neuroscience in the field of vision were reviewed, and the application of research methods of cognitive psychology in neural network robustness were discussed.Human visual system has advantages in learning and abstract ability, whill neural network models have better performance in calculation speed and memory.The difference between the physiological structure of human brain and the logical structure of neural network models is the key factor leading to the problem of robustness of neural networks.The research of visual robustness requires deeper understanding of human visual system.Revealing the differences in cognitive mechanism between human visual system and neural network models and effectively improving the algorithm are the development trends of neural network robustness and even artificial intelligence.…”
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Association of Pneumatosis Intestinalis With Surgical Outcomes and Mortality: A Matched, Retrospective Cohort Study and Literature Review by Kyle D. Klingbeil, MD, MS, Hila Zelicha, PhD, RD, Yijun Chen, MD, Douglas S. Bell, MD, Edward H. Livingston, MD, FACS, AGAF

“…A radiologic diagnosis of PI was then assessed using natural language processing techniques followed by confirmation using manual chart review. …”
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Evaluating antibacterial and antioxidant properties of sericin recovered from cocoons of Bombyx mori, Gonometa postica and Samia ricini in Kenya. by Mwangi G Kanyora, Timothy M Kegode, Justus Kurgat, Harrison Kibogo, George Asudi, Chrysantus M Tanga, Workneh Ayalew, Subramanian Sevgan, Nelly Ndungu

“…In fact, wound management has become more challenging since most of these microbes have developed resistance against commonly used conventional antibiotics thus making it necessary to develop natural products with both antibacterial and antioxidant activities. …”
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Impact of a potential Chlamydia vaccine in the USA: mathematical modelling analyses by Hiam Chemaitelly, Laith J Abu-Raddad, Houssein H Ayoub, Susanne F Awad, Monia Makhoul

“…The model’s parameters were chosen based on current knowledge from the literature on CT’s natural history and epidemiology. The model’s calibration used age-specific CT prevalence data sourced from the biannual rounds of the National Health and Nutrition Examination Surveys. …”
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Determinants of growth differentiation factor 15 plasma levels in outpatients with peripheral arterial disease by Emma Skau, Philippe Wagner, Jerzy Leppert, Johan Ärnlöv, Pär Hedberg

“…The relations between GDF-15 concentrations (transformed with the natural logarithm) and the different determinants were evaluated using uni- and multivariable linear regression models. …”
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Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults by Yuankang Zhu, Zhenlin Yang, Yuhao Chen, Lingzi Qian, Changning Hao, Liangshi Hao, Boshen Yang, Junli Duan

“…The association between natural logarithm (ln)-transformed glyphosate exposure in urine and CVH was examined using weighted linear regression and restricted cubic spline (RCS) models. …”
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