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38921
Transcription factor KLF2 is associated with the dysfunctional status of NK cells and the prognosis of pediatric B-ALL patients
Published 2025-01-01“…BackgroundNatural killer cells, an important component of the innate immune system, can directly recognize and lyse virally infected or transformed cells. …”
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38922
A tendency towards leaf rust resistance decrease in common wheat introgression lines with genetic material from Aegilops speltoides Tausch
Published 2018-08-01“…The estimation of specimens in the field conditions on natural infectious background showed that the Ae. speltoides accessions were immune to leaf rust, however, а tendency towards increasing susceptibility of the introgressive lines and varieties was detected. …”
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38923
Deteksi Detak Jantung Menggunakan Remote Photoplethysmograph dengan Perubahan Jarak dan Jenis Kamera Secara Dinamis
Published 2024-08-01“…Proses pengukuran dengan menggunakan peralatan konvensional sebagaimana tersebut diatas masih diperlukan kontak secara fisik pada anggota tubuh jika seringkali dilakukan dapat menyebabkan iritasi pada kulit sehingga hal tersebut kurang efisien karena proses interaksinya kurang natural dan intuitif. Pada penelitian ini menerapkan proses deteksi sinyal PPG untuk pembacaan detak jantung melalui dahi secara dinamis menggunakan computer vision secara realtime tanpa diperlukan kontak fisik, konsep tersebut disebut dengan istilah remote PhotoPlethysmoGraph (rPPG). …”
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38924
Distinct effects of fine and coarse aerosols on microphysical processes of shallow-precipitation systems in summer over southern China
Published 2025-02-01“…<p>Densely populated southern China, adjacent to the South China Sea, which is associated with shallow precipitation during summer, is an open-air natural laboratory for studying the impact of aerosol particles on shallow-precipitation events. …”
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38925
A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation
Published 2025-01-01“…USP4 promoted stemness by stabilizing the β-catenin and Twist1 proteins in CRC cells. A natural small molecule product U4-I05 diminished the stem-like features of CSCs and enhanced their sensitivity to oxaliplatin and 5-fluorouracil by targeting inhibition of its deubiquitinating enzyme activity through binding the catalytic domain of USP4 (311 cysteine site) at nanomolar concentrations, triggering proteasome-mediated degradation of β-catenin and Twist1. …”
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38926
Uvaol attenuates TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells by modulating expression and membrane localization of β-catenin
Published 2025-01-01“…Classical inducers associated with the maintenance of EMT, such as TGF-β1, have become targets of several anti-EMT therapeutic strategies. Natural products from the pentacyclic triterpene class have emerged as promising elements in inhibiting EMT. …”
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38927
A Preliminary Evaluation of Variability, Genetic Estimates, and Association among Phenotypic Traits of African Yam Bean Landraces from Ghana
Published 2023-01-01“…A field experiment was conducted at the Research and Teaching Farm, School of Agriculture and Technology (SOAT), University of Energy and Natural Resources (UENR), Dormaa Ahenkro Campus, Ghana, to determine the genetic variability, heritability, genetic advance, and correlation among growth and yield traits of the African yam bean in Ghana. …”
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38928
CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1
Published 2025-02-01“…ABSTRACT Lactiplantibacillus plantarum, a natural inhabitant of the human body, is a promising candidate vehicle for vaccine delivery. …”
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38929
Examining Prenylated Xanthones as Potential Inhibitors Against Ketohexokinase C Isoform for the Treatment of Fructose-Driven Metabolic Disorders: An Integrated Computational Approa...
Published 2025-01-01“…Ketohexokinase C (KHK-C), a key enzyme in fructose metabolism, is a promising therapeutic target. α-Mangostin, a naturally occurring prenylated xanthone, has been identified as an effective KHK-C inhibitor, prompting exploration of its analogs for enhanced efficacy. …”
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38930
Effects of Extraction Temperature on Physicochemical Properties and Antioxidant and Immunomodulatory Activities of Polysaccharides from Lycium ruthenicum Murr.
Published 2025-02-01“…Therefore, LRP60 and LRP80 from Lycium ruthenicum Murr. could serve as potential natural antioxidants or immunomodulators.…”
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38931
Characteristics and Differences in the Antler Velvet Microbiota During Regeneration
Published 2024-12-01“…The wound formed by antler velvet shedding can naturally achieve regenerative restoration, but the changes in microbial composition that occur during antler velvet regeneration are largely unknown. …”
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38932
<i>Phytophthora</i> Species and Their Associations with Chaparral and Oak Woodland Vegetation in Southern California
Published 2025-01-01“…Additionally, California’s natural areas, characterized by a Mediterranean climate and dominated by chaparral (evergreen, drought-tolerant shrubs) and oak woodlands, lack sufficient baseline knowledge on <i>Phytophthora</i> biology and ecology, hindering effective management efforts. …”
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38933
Antimicrobial, Antiradical Activity, and X-Ray Fluorescence Spectroscopy Analysis of Aloe otallensis Plant Used in Traditional Medicine in Southern Ethiopia
Published 2024-01-01“…The results provide valuable insights into the use of medicinal plants to treat diseases and support the development of natural therapeutics.…”
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38934
Effects of Different Organic Fertilizers on Yield and Yield-Related Characteristics in Black Cumin (Nigella sativa L.) Cultivation Under the Ecological Conditions of Tokat, Türkiye...
Published 2025-01-01“…This finding reveals that the use of organic fertilizer in black cumin cultivation is an important alternative for farmers who want to both increase yield and prefer a natural production method.…”
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38935
Metabolic phenotype of adult mice offspring obtained from different variants of embryo transfer
Published 2020-12-01“…Animals were separated in 4 groups according to the variant of embryo transplantation: group (control) – natural mating; group (2cl-bl) – incubation of 2-cell up to blastocysts; group (2cl-2cl) – removal and transplantation of the 2-cell embryo without incubation; group (Bl-bl) removal and transplantation of the blastocysts without incubation. …”
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38936
Poesía catalana popularizante de voz femenina en cancioneros, ensaladas y pliegos sueltos del siglo XVI
Published 2025-01-01“…Por ese motivo, la presente investigación recopila las canciones de mujer catalanas procedentes de cancioneros, ensaladas, pliegos sueltos y otras fuentes manuscritas e impresas del siglo XVI, examina sus principales rasgos temáticos y formales e identifica sus antecedentes en la tradición lírica medieval de la Corona de Aragón (siglos XIII-XV), de la que es su continuación natural. Asimismo, el trabajo explora las influencias literarias que recibió el corpus de estudio (la castellana y la galorrománica, principalmente), lo que contribuye a situar la literatura catalana en su contexto románico y a precisar los modelos poéticos que asumió durante el Renacimiento. …”
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38937
De la façon de nommer aux usages des plantes adventices des cultures en pays Jbala (nord du Maroc)
Published 2017-10-01“…It is to be noted that the way they refer to the natural world is very different from the way cultivated plants are named. …”
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38938
The Muscadine Grape (Vitis rotundifolia Michx)
Published 2020-11-01“… The muscadine grape is native to the southeastern United States and was the first native grape species to be cultivated in North America. The natural range of muscadine grapes extends from Delaware to central Florida and occurs in all states along the Gulf Coast to east Texas. …”
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38939
Application of Magnetic Aquatic Plant Biochar for Efficient Removal of Antimony from Water: Adsorption Properties and Mechanism
Published 2024-12-01“…Antimony (Sb) pollution in natural water bodies can cause significant harm to aquatic ecosystems. …”
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38940
The Protective Role of Ambient Ultraviolet Radiation Against Dementia: An Ecological Analysis of Global Data
Published 2025-01-01“…Subgroup analyses revealed that the protective effects of UVR were particularly pronounced in developing countries, where limited access to vitamin D supplementation, combined with greater exposure to natural sunlight may enhance its influence. Conclusion Lower ambient UVR levels are associated with higher dementia incidence rates worldwide, suggesting a critical role for UVR in mitigating dementia risk. …”
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