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  4. 30144

    Health economic evaluation of different colorectal cancer screening strategies in Hubei province: a Markov simulation analysis based on local cancer registration and domestic study... by Jie JI, Yuying WANG, Duan ZHUO, Yuhan LIU, Jiaxi PENG, Ruijingfang JIANG, Hao WU, Song LIU, Lijian ZHAO, Jian WANG, Bing MAO, Shida ZHU, Hongbing TAO

    Published 2024-11-01
    “…Data on the probabilities, screening costs, and medical costs required for the colorectal cancer natural history model were extracted from the Hubei Provincial Cancer Registration (2020)/Mortality Surveillance (2013 – 2017) dataset and the literature review and entered into the model. …”
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  5. 30145

    Screening of Genes Related to Resistance to Bacterial Leaf Blight in Oryza officinalis by using RNA-seq Technology by Yayun YANG, Feifei ZHANG, Famei ZHANG, Xinxiang A, Chao DONG, Cuifeng TANG, Chunyun YANG, Luyuan DAI

    Published 2024-11-01
    “…【Objective】Oryza officinalis belongs to the CC chromosome group of rice genus, and it had accumulated a large number of resistance genes that adapt to harsh environments during long-term natural survival. Based on transcriptome sequencing (RNA-seq), disease resistance related genes could be discovered, laying a foundation for researches on gene function and regulatory mechanisms.…”
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  6. 30146

    Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis by Chuanxin Liu, Xiaobin Huang, Jiao Kong, Xuejiao Li, Yuming Wang, Fangfang Zhang, Jiajia Duan

    Published 2025-01-01
    “…This approach transforms fragmented toxicity indicators into systematic evidence of toxicity, presenting a hierarchical progression of toxicity evidence and avoiding data accumulation in natural drug toxicology. Our findings represent a significant breakthrough in the elucidation of the mechanisms of hepatotoxicity induced by podophyllotoxin.…”
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  7. 30147

    Global, regional, and national burdens of heart failure in adolescents and young adults aged 10–24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease St... by Chengzhi Yang, Yuhe Jia, Changlin Zhang, Zening Jin, Yue Ma, Xuanye Bi, Aiju Tian

    Published 2025-01-01
    “…According to different underlying causes of HF, both high-income countries and low- and middle-income countries need to better prevent HF in adolescents and young adults. Funding: National Natural Science Foundation of China (grant 81900452) and Training Fund for Open Projects at Clinical Institutes and Departments of Capital Medical University (grant CCMU2022ZKYXY003).…”
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