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    Immune Profile Differences between IgG4-Related Diseases and Primary Sjögren’s Syndrome by Qin Y, Shang L, Wang Y, Feng M, Liang Z, Wang N, Gao C, Luo J

    Published 2025-01-01
    “…Cytokines assays were performed using cytometric bead array.Results: Compared to pSS, IgG4-RD patients had higher IgG4 (p < 0.001) and lower IgG1 (p =0.014). The natural killer (NK) cells (p = 0.004), CD4+ T cells (p = 0.028), and TBNK cells (p = 0.040) were increased in IgG4-RD compared to pSS. …”
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    High tumor mutational burden predicts favorable response to anti-PD-(L)1 therapy in patients with solid tumor: a real-world pan-tumor analysis by Sehhoon Park, Jaeyun Jung, You Jeong Heo

    Published 2023-04-01
    “…Among the TMB-H patients, those who responded to anti-PD-L1 therapy had numerous active immune cells that infiltrated the tumor regions during the DSP analysis. Natural killer cells (p=0.04), cytotoxic T cells (p&lt;0.01), memory T cells (p&lt;0.01), naïve memory T cells (p&lt;0.01), and proteins related to T-cell proliferation (p&lt;0.01) were observed in a responder group compared with a non-responder group. …”
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