Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects by Ada Alice Dona, Theophilus Tandoh, Lokesh Nigam, Mahmoud Singer, Enrico Caserta, Mariam Murtadha, Yinghui Zhu, Milad Moloudizargari, Preeti Sharma, Ottavio Napolitano, Janet Winchester, Arnab Chowdhury, Alex Pozhitkov, James F. Sanchez, Hawa Vahed, Guido Marcucci, Matt Coffey, Gerard Nuovo, Douglas W. Sborov, Flavia Pichiorri, Craig C Hofmeister

“…Abstract Background Reovirus (RV) is an oncolytic virus with natural tropism for cancer cells. We previously showed that RV administration in multiple myeloma (MM) patients was safe, but disease control associated with viral replication in the cancer cells was not observed. …”
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NEOPOSITIVISMO Y CONOCIMIENTO REGIONAL: LA HISTORIA DE UNA FRUSTRACIÓN by Gerardo M. de Jong

“…Esta explicación comprehensiva del espacio regional requiere del trabajo interdisciplinario en estrecho contacto con otras ciencias sociales (especialmente economistas y sociólogos) y con las disciplinas que tienen capacidad de producir conocimiento sintético acerca del comportamiento del medio natural. En este sentido, es necesario construir una crítica de los aportes de algunos de los estudiosos, de vertiente neopositivista, que se ocuparon del comportamiento del espacio regional.…”
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Evaluating Dispersion of Residential CO and NOx Emissions with the Help of Different Models in Körfez District, Kocaeli Province by Kazım Demirarslan, Şenay Çetin Doğruparmak

“…The residential area is 5.31 km2 and natural gas, fuel-oil, wood, and coal are used as heating fuels in this district. …”
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Plasmid-free production of the plant lignan pinoresinol in growing Escherichia coli cells by U. Joost Luelf, Alexander Wassing, Lisa M. Böhmer, Vlada B. Urlacher

“…As (-)-podophyllotoxin is traditionally isolated from endangered and therefore limited natural sources, there is a particular need for biotechnological production. …”
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ANTHROPOLOGICAL SPHERE OF HUMAN EXISTENCE: RESTRICTIONS ON HUMAN RIGHTS DURING PANDEMIC THREATS by V. S. Blikhar, I. M. Zharovska

“…Today, international guiding principles on human rights response to global natural threats have been updated. However, there are still no specific legal recommendations (both at the international and national levels) concerning measures on human rights protection during outbreaks of various infectious diseases. …”
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The regulatory effects of (p)ppGpp and indole on cAMP synthesis in <i>Escherichia coli</i> cells by N. M. Kashevarova, E. A. Khaova, A. G. Tkachenko

“…The mutual influence of network signaling molecules represented by cells’ natural metabolites, including indole and second messengers (p)ppGpp and cAMP, is hitherto not well understood, being the aim of this study. …”
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A century of Azolla filiculoides biocontrol: the economic value of Stenopelmus rufinasus to Great Britain by Corin F. Pratt, Kate Constantine, Suzy V. Wood

“…Abstract Background The invasive aquatic fern Azolla filiculoides has been present in Great Britain (GB) since the end of the nineteenth century, while its specialist natural enemy, the weevil Stenopelmus rufinasus was first recorded nearly four decades later, in 1921. …”
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Analysis of the behaviour of the Tukad Buluk Poh flood water at the Gilimanuk - Denpasar National Road Crossing by Hidayat Acep, Suprapti, Isradi Muhammad, Dwi Praptoyo Riska

“…In most of Indonesia, floods are a common natural disaster that spreads into several watersheds during the rainy season. …”
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Effect of lethal yellow (AY) mutation and photoperiod alterations on mouse behavior by E. Y. Bazhenova, D. V. Fursenko, N. V. Khotskin, I. E. Sorokin, A. V. Kulikov

“…Decrease in natural illumination in fall/winter months causes depressive-like seasonal affective disorders in vulnerable individuals. …”
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Humification and Humic Acid Composition of Suspended Soil in Oligotrophous Environments in South Vietnam by E. V. Abakumov, O. A. Rodina, A. K. Eskov

“…Humification is considered to be a global process that is implemented in soils and organic sediments and also in natural water and air. The term “suspended soils” has become increasingly common in recent years. …”
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Objects and subjects of registration and permit-licensing procedures in the activities of the National Police by О. А. Bud

“… • The range of participants in registration and permit-licensing procedures in the activities of the National Police has been outlined: 1) the entity authorized to implement the specified types of procedures, i.e. units of the National Police of Ukraine; 2) natural and legal persons who receive these services; 3) third parties who facilitate the implementation of procedures…”
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A tale for two roles: Root-secreted methyl ferulate inhibits P. nicotianae and enriches the rhizosphere Bacillus against black shank disease in tobacco by Siqi Ma, Qianru Chen, Yanfen Zheng, Tingting Ren, Rui He, Lirui Cheng, Ping Zou, Changliang Jing, Chengsheng Zhang, Yiqiang Li

“…The root exudate methyl ferulate, a naturally occurring and relatively non-toxic antifungal agent, has been applied to control postharvest pathogens and preserve foodstuffs and has not been used in plant disease control. …”
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The InBIO Barcoding Initiative Database: contribution to the knowledge of DNA barcodes of the vascular plants of north-eastern Portugal by João Queirós, Rodrigo Silva, Catarina J. Pinho, Hélia Vale-Gonçalves, Ricardo Pita, Paulo Alves, Pedro Beja, Joana Paupério, Miguel Porto

“…This is one of the public releases of the IBI database, which provides genetic and distributional data for several taxa.All vouchers are deposited in the Herbarium of the Museum of Natural History and Science of the University of Porto (MHNC-UP) and their DNA barcodes are publicly available in the Barcode of Life Data System (BOLD), NCBI GenBank online databases and International Nucleotide Sequence Database Collaboration (INSDC).…”
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Chickens productivity selection affects immune system genes by А. М. Borodin, Ya. I. Alekseev, K. E. Gerasimov, N. V. Konovalova, E. V. Тerentjeva, D. N. Efimov, Zh. V. Emanuilova, L. I. Tuchemskiy, A. A. Komarov, V. I. Fisinin

“…It can be assumed that the fixation of the allele in the DMA gene (SNP Gga_rs15723) is associated with artificial or natural selection, consistent in broilers and layers. …”
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Ovarian Reserve: A Critical Indicator of Female Reproductive Health by Julia Ufnal, Anna Wolff, Maria Morawska, Dominika Lewandowska, Dominika Rosińska-Lewandoska, Marcelina Szewczyk, Klaudia Kożuchowska, Dawid Pilarz, Kinga Jarosz, Szymon Gruszka

“…The finite pool of oocytes established in utero declines progressively throughout life, which is a natural process but may result in diminished ovarian reserve (DOR) in some women. …”
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Worldwide patterns and trends in ovarian cancer incidence by histological subtype: a population-based analysis from 1988 to 2017Research in context by Yi-Fan Wei, Li Ning, Yi-Lin Xu, Jing Ma, Dong-Run Li, Zan-Fei Feng, Fang-Hua Liu, Yi-Zi Li, He-Li Xu, Peng Li, Yong-Pei Yu, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Chun-Qing Lin, Ting-Ting Gong, Qi-Jun Wu, Jing-He Lang

“…Funding: The National Key Research and Development Program of China (No.2022YFC2704205), the Natural Science Foundation of China (No.82073647, 82373674, and 82103914), Outstanding Scientific Fund of Shengjing Hospital, 345 Talent Project of Shengjing Hospital of China Medical University, the Max Planck – University of Helsinki Center from the Jane and Aatos Erkko Foundation (No.210046), the Max Planck Society (No.5714240218), the University of Helsinki (No.77204227), and the European Union (ERC Synergy, BIOSFER, 101071773).…”
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Uso de perifiton en un sistema de policultivo en agro acuicultura integrada en la comunidad indígena de Jimaín, Sierra Nevada de Santa Marta (Colombia) by J. C. Durán-Izquierdo, R. J. Mindiola-Romo, G. A. Wills-Franco, S. C. Pardo-Carrasco, A. P. Muñoz-Ramírez

“…Así mismo, el uso de perifiton se ha convertido recientemente en una alternativa viable por el aporte de alimento natural de bajo costo. El objetivo de este estudio fue evaluar el efecto del perifiton sobre el desempeño productivo del policultivo Piaractus sp. …”
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Influence of volatiles (H$_{2}$O and CO$_{2}$) on shoshonite phase equilibria by Vetere, Francesco, Namur, Olivier, Holtz, Francois, Almeev, Renat, Donato, Paola, Frondini, Francesco, Cassetta, Michele, Pisello, Alessandro, Perugini, Diego

“…Clinopyroxene (Cpx) is the main crystallising phase and is compositionally analogous to Cpx crystals found in the natural rock. Plagioclase (Pl) is stable only for water activity lower than 0.1, whereas Fe–Ti oxides are present in all experimental runs, except for those where log fO$_{2}$ was lower than ${-}$9, (${\Delta }$NNO ${-}$0.11) irrespective of the presence of CO$_{2}$. …”
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Efecto del aceite esencial de orégano sobre el desempeño productivo de ponedoras y la estabilidad oxidativa de huevos enriquecidos con ácidos grasos poliinsaturados by R. E. Ortiz, G. Afanador, D. R. Vásquez, C. Ariza-Nieto

“…El AEO mostró potencial como antioxidante natural en la dieta de las ponedoras mejorando la estabilidad oxidativa de los huevos almacenados a 4°C hasta por 60 días.…”
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Las cataratas del Lobé, un patrimonio geocultural excepcional en la costa camerunesa, entre el turismo duradero y la conservación de las identidades culturales by Mesmin Tchindjang, Marcel Hugues Etoga

“…Las informaciones recogidas evidencian un potencial turístico (natural, cultural e histórico) importante y diversificado, caracterizado por un medio físico atractivo (relieve, clima y vegetación), y la existencia de poblaciones sugerentes. …”
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