Safety of a change of specifications of phytosterols/phytostanols as a novel food pursuant to Regulation (EU) 2015/2283 by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Monika Neuhäuser‐Berthold, Helle Katrine Knutsen, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Wolfgang Gelbmann, Harry J. McArdle

“…Regarding the maximum limit of the specification parameter ‘other sterols/stanols’, the applicant asks for an increase from currently less than 3% to less than 7% to better reflect and cover the natural composition and proportions of sunflower‐based phytosterols/phytostanols, noting that the existing specifications have been established largely based on the NF when sourced from soy. …”
Get full text

Drugs and Constipation in Elderly in Nursing Homes: What Is the Relation? by Gunvor S. Fosnes, Stian Lydersen, Per G. Farup

“…Reduced activity of daily living (OR = 0.71, 95% CI : 0.60–0.84, P<0.001), other antidepressants (N06AX) (OR 3.08, 95% CI : 1.09–8.68, P=0.03), and benzodiazepine derivatives (N05BA) (OR = 2.80, 95% CI : 1.12–7.04, P=0.03) were significantly associated with constipation; drugs with markedly anticholinergic effect (OR = 3.7, 95% CI : 0.78–17.53, P=0.10), natural opium alkaloid (N02AA) (OR = 5.01, 95% CI : 0.95–25.94, P=0.06), and propionic acid derivatives (M01AE) (OR = 7.00, 95% CI : 0.75–65.08, P=0.09) showed a trend. …”
Get full text

Accurate Diagnosis and Treatment of Painful Temporomandibular Disorders: A Literature Review Supplemented by Own Clinical Experience by Adam Andrzej Garstka, Lidia Kozowska, Konrad Kijak, Monika Brzózka, Helena Gronwald, Piotr Skomro, Danuta Lietz-Kijak

“…The following keywords were used to build the full list of references: TMD, pain, temporomandibular joint (TMJ), TMJ disorders, occlusal splint, relaxing splints, physiotherapy TMD, pharmacology TMD, natural therapy TMD, diagnostic criteria for TMD, and DC/TMD. …”
Get full text

Problems of creating antibody phage libraries and their solutions by V. S. Aripov, N. V. Volkova, A. A. Ilyichev, D. N. Shcherbakov

“…The diversity, whether natural or obtained by combinatorial chemistry, is the basis of any library. …”
Get full text

Características físico-químicas e fenóis totais em frutos de juçara em diferentes condições ambientais by Rodolfo Francisco Cravo Filho, Rafael Navas, Estela Maria Gonçalves

“…A espécie correspondeu a um dos produtos mais explorados na Mata Atlântica e, atualmente, existe cultivo fora do habitat natural com o objetivo de atender necessidades comerciais e buscar sustentabilidade para seu uso. …”
Get full text

Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway by Abdulla Y. Al-Taher, Mohamed A. Morsy, Rehab A. Rifaai, Nagwa M. Zenhom, Seham A. Abdel-Gaber

“…Oxidative stress and inflammation have been proved in the development of MTX toxicity. Paeonol is a natural phenolic compound with various pharmacological activities including antioxidant and anti-inflammatory properties. …”
Get full text

Comprehensive Chloroplast Genome Analysis of Four <i>Callitriche</i> (Plantaginaceae) Species for Phylogenetic and Conservation Insights by Zirui Zhang, Wenbo Shi, Siqi Hu, Lanruo Mou, Chao Shi, Bingyue Zhu, Jing Yang

“…<i>Callitriche</i> species are capable of purifying water, promoting wetland restoration, and providing natural shelters. Moreover, they can be utilized as horticultural plants for landscape greening. …”
Get full text

Solid-State Modification Strategies for Alpha-Mangostin Solubility Enhancement: A Review on Recent Progress by Nurin Syamimi Ahmad Izuren Shah, Muhammad Taher Bakhtiar, Syarifah Abd Rahim, Fatmawati Adam, Wan Hazman Danial, Mohd Rushdi Abu Bakar

“…Alpha-mangostin (AM), a promising natural compound with various pharmacological properties, faces significant limitations due to its low aqueous solubility. …”
Get full text

Variability and interpopulation differentiation of the rare species Gueldenstaedtia monophylla Fisch. (Fabaceae) by I. Yu. Selyutina, E. S. Konichenko, O. V. Dorogina

“…Genetic variability of the rare species Gueldenstaedtia monophylla from 7 natural populations in the central part of its range (Ongudai district, Altai Republic) was studied. …”
Get full text

Analysis of ChatGPT-Generated Codes Across Multiple Programming Languages by Sally Almanasra, Khaled Suwais

“…With advancements in large language models like ChatGPT, developers can now generate code from natural language prompts, a task that traditionally required significant manual input and expertise. …”
Get full text

Positive Response of Hyoscyamus pusillus Callus Cultures to Exogenous Melatonin on Biochemical Traits and Secondary Metabolites under Drought Conditions by Shamil I. Neamah, Nisreen A. Jdayea

“…There is increased attention from specialists toward producing natural compounds from plant tissues through the combined use of elicitors. …”
Get full text

Changes in Vitamin E and β-Carotene Contents in Various Edible Cassava Leaves (Manihot esculenta Crantz) of Different Ages across Multiple Seasons by Alphonse Laya, Benoît B. Koubala

“…Edible cassava leaves can be considered as sources of vitamin E for natural dietary antioxidant during different ages, and the best time to harvest EN and AD varieties is at 6MAP on the basis of α-tocopherol equivalent or content of biologically active vitamin E content, and EN and AD varieties performed the overall best. …”
Get full text

Quantifying soil surface erosion by Philippe, Pierre, Benahmed, Nadia

“…This review first introduces the general context of soil erosion, an omnipresent natural process involving a wide variety of spatial and temporal scales. …”
Get full text

Biodiversity conservation and threat reduction in Kibale and Queen Elizabeth conservation areas, Uganda by Joseph Katswera, Norah M. Mutekanga, Charles K.Twesigye

“…The two conservation areas are majorly threatened by anthropogenic threats, natural threats, and administrative constraints. The wildlife agency should integrate ecosystem health into the conservation agenda. …”
Get full text

Assessment of the size and shape of berries using the ImageJ program on the example of honeysuckle by D. Yu. Nokhrin, L. V. Ufimtseva, N. V. Glaz

“…The prospects of using the surface roughness index for quantitative characterization of the degree of deviation of fruits from their natural shape due to mechanical and other deformations are discussed.Conclusion. …”
Get full text

Implementing a rapid geographic range expansion - the role of behavior changes by Logan, Corina, McCune, Kelsey, LeGrande-Rolls, Christa, Marfori, Zara, Hubbard, Josephine, Lukas, Dieter

“…They are behaviorally flexible and highly associated with human-modified environments, eating a variety of human foods in addition to foraging on insects and on the ground for other natural food items. They offer an opportunity to assess the role of behavior change over the course of their expansion. …”
Get full text

Enhanced biomechanical and biological performance of titanium scaffolds with gradient in pore sizes by Ara Jung, Jinju Jang, Hun Yeong Ban, Hee Jin Kim, Bomi Gweon, Dohyung Lim

“…Collectively, these findings suggest that the design strategy of the Type 2 gradient scaffold is beneficial not only for achieving biomechanical compatibility by closely mimicking natural bone but also for promoting osteogenesis and neovascularization.…”
Get full text

Soil quality indicator-based land productivity modelling for agricultural sustainability. by Ibraheem A H Yousif, Ali Abdel Hamid, Abdalsamad A Aldabaa, Sayed A Hassanein, Nazih Y Rebouh, Elsayed Said Mohamed, Mohamed S Shokr

“…Rapid population expansion has made food security a global concern for humanity, necessitating a sustainable assessment of natural resources. Well evaluated and managed soil is one of the most significant resources that can assist close the gap between supply and demand for food to attain food security. …”
Get full text

Towards New Scaffolds for Antimicrobial Activity—In Silico/In Vitro Workflow Introducing New Lead Compounds by Maria Mangana, George Lambrinidis, Ioannis K. Kostakis, Ioanna Kalpaktsi, Marina Sagnou, Chrysoula Nicolaou, Emmanuel Mikros, Stylianos Chatzipanagiotou, Anastasios Ioannidis

“…Computational approaches and natural product exploitation offer potential solutions to accelerate drug discovery. …”
Get full text

Experimental Investigation on Propagation Behavior of Hydraulic Fractures in Coal Seam during Refracturing by Xun Sun, Shicheng Zhang, Xinfang Ma, Yushi Zou, Guanyu Lin

“…In this study, laboratory refracturing experiments were conducted on large natural coal specimens under various triaxial stress states to investigate the propagation of HFs in coal seams. …”
Get full text