Diosgenin and solasodine-based saponins and sapogenines—Effects of structural modifications on Panagrellus redivivus, Spodoptera littoralis and Trichoderma reesei by Christina Rodler, Johann Schinnerl, Miriam Schalamun, Wolfgang Hinterdobler, Lothar Brecker

“…Saponins are a large class of plant natural products that exhibit a great variety of biological and pharmacological properties. …”
Get full text

Flexural behavior of high-strength reinforced concrete beam with hybrid fiber under normal and high temperature by Ahmed Ashteyat, Ala Obaidat, Tarik Kharabsheh, Ahmed Harahsheh

“…Heated samples were subjected to 600 ℃ for 3 hours and left to cool off naturally before testing. The test results show that using BF and SF significantly increased the tensile strength of unheated cylinders, with the optimum fiber content of 1% BF - 1.5% SF achieving an increase of 163% over the control. …”

Targeting epithelial-mesenchymal transition signaling pathways with Dietary Phytocompounds and repurposed drug combinations for overcoming drug resistance in various cancers by A.N.K.V. Sravani, John Thomas

“…This review summarises major EMT-associated pathways and their cross talks with their mechanistic insights and the role of different dietary phytochemicals (curcumin, ginger, fennel, black pepper, and clove) and their natural analogs and also repurposed drugs (metformin, statin, chloroquine, and vitamin D) which are commonly used in regulating EMT in various preclinical studies. …”
Get full text

OIE and FAO join forces to counter ASF by N. V. Lebedev, A. S. Igolkin, K. N. Gruzdev

“…African swine fever (ASF) is an infectious disease of domestic and wild pigs, which went beyond its natural range (African continent) in the XXI century and since 2007 (emergence in Georgia) has spread to many European and Asia-Pacific countries. …”
Get full text

THE ROLE OF DIGITAL MEDIA IN DEVELOPING AN ONLINE ANATOMY COURSE FOR THE ACQUISITION OF PRE-SERVICE SCIENCE TEACHERS' HEALTH LITERACY by Handan Ürek

“…Besides, online learning can also be an effective way to carry out education after natural disasters such as earthquakes. This study aimed to detect the effectiveness of an online anatomy course enriched with digital media news on pre-service science teachers’ course attitudes and health literacy after two major earthquakes hit the east and southeast of Turkey in 2023. …”
Get full text

Dietary Shifts Among the Developmental Stages of the Ectoparasite, Argulus japonicus (Crustacea; Branchiura), Mirror Ontogeny as Shown Through Differences in Stable Isotope Ratios... by Beric M. Gilbert, Milen Nachev, Bernd Sures, Annemariè Avenant‐Oldewage

“…ABSTRACT Food web architecture and trophic interactions between organisms can be studied using ratios of naturally occurring stable isotopes of carbon (13C/12C) and nitrogen (15N/14N). …”
Get full text

Effectiveness of Combination of Chitosan Gel and Hydroxyapatite from Crabs Shells (Portunus pelagicus) Waste as Bonegraft on Periodontal Network Regeneration through IL-1 and BMP-2... by Asdar Gani, Risfah Yulianty, Supiaty Supiaty, Machirah Rusdy, Gustivanny Dwipa Asri, Dian Eka Satya, Ayu Rahayu Feblina, Harun Achmad

“…Periodontitis can be treated by regenerating periodontal tissue using a bone graft. Several natural materials such as chitosan and minerals such as hydroxyapatite can be developed to increase periodontal tissue regeneration. …”
Get full text

Assessment of the Vanillin Anti-Inflammatory and Regenerative Potentials in Inflamed Primary Human Gingival Fibroblast by Erica Costantini, Bruna Sinjari, Katia Falasca, Marcella Reale, Sergio Caputi, Srinivas Jagarlapodii, Giovanna Murmura

“…Vanillin is a well-known natural compound with potential anti-inflammatory capacity. …”
Get full text

YOLOv8n-CA: Improved YOLOv8n Model for Tomato Fruit Recognition at Different Stages of Ripeness by Xin Gao, Jieyuan Ding, Ruihong Zhang, Xiaobo Xi

“…This study addresses the challenges of tomato maturity recognition in natural environments, such as occlusion caused by branches and leaves, and the difficulty in detecting stacked fruits. …”
Get full text

Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin by Jichao Sun, Dinglan Wu, Liuhai Zheng, Huifang Wang, Jihao Zhou, Guangwei Shi, Jingbo Ma, Yuke Jiang, Zhiyu Dong, Jiexuan Li, Yuan-Qiao He, Chengchao Xu, Zhijie Li, Jigang Wang

“…Background Chimeric antigen receptor natural killer (CAR-NK) therapy holds great promise for treating hematologic tumors, but its efficacy in solid tumors is limited owing to the lack of suitable targets and poor infiltration of engineered NK cells. …”
Get full text

Creativity in children’s speech development: a case study of Persian speaking children by Samad Mirza Suzani

“…To this end, following a longitudinal observation approach, the naturalistic and experimental aspects of child language acquisition were examined as it was considered to have the advantage of producing spontaneous natural data. The data consisted of utterances by a number of children at an age range of 1;10 to 4;10 since it is considered a productive period for the creation of new words. …”
Get full text

Biomechanics Parameters of Gait Analysis to Characterize Parkinson’s Disease: A Scoping Review by Michela Russo, Marianna Amboni, Noemi Pisani, Antonio Volzone, Danilo Calderone, Paolo Barone, Francesco Amato, Carlo Ricciardi, Maria Romano

“…Most gait analyses in PD patients have been conducted at self-selected walking speeds to capture natural movement, although studies have also examined gait under various conditions. …”
Get full text

Quantitative 3-D investigation of faulting in deep mining using Mohr–Coulomb criterion and slip weakening law by Yatao Li, Xuehong Gao, Jianwei Yang, Erhu Bai

“…Additionally, this study confirms that mining-induced fault slips exhibit self-similar behaviors analogous to natural faulting, with a proportional relationship between slip distribution and static stress drop, validated through robust numerical analysis. …”
Get full text

Enhancing Qualitative Research: The Use of Design Probes and Cooking Sessions Deepens the Understanding of 9- to 11-Year-Old Children’s Food Perceptions by Lotte Pater, Elizabeth H. Zandstra, Vincenzo Fogliano, Bea L. P. A. Steenbekkers

“…These new child-centered qualitative participatory research methods enable to perform the intervention in a natural and real-life context, favouring the expression of thoughts about the research topic. …”
Get full text

GREEN FINANCE: CASE OF LITHUANIA by Giedrė Lapinskienė, Gitana Mečėjienė, Laima Steiblienė

“…The rapid degradation of the natural environment lays the foundation for policymakers to implement new mechanisms to stimulate the transformation of the economy. …”
Get full text

Mapping groundwater potential zone by robust machine learning algorithms & remote sensing techniques in agriculture dominated area, Bangladesh by M. M. Shah Porun Rana, Muhammad Tauhidur Rahman, Md Fuad Hassan

“…These resources of Bangladesh are under tremendous pressure from both natural and human-caused factors. Groundwater is essential for fulfilling water requirements in the agricultural Pabna district of Bangladesh, where over-extraction for local, manufacturing, and farming uses has led to considerable water shortages. …”
Get full text

The Problems of Implementing Imkan Rukyat in the Case of an Invisible Hilal (Crescent): A Perspective of Syafi’i Scholars by Hudi Hudi, Ahmad Rofiq

“…However, some Syafi’i scholars permit the determination of the start of the new lunar month the next day based on hisab imkan rukyat, provided that the calculation is done by at least seven qualified astronomers who are unlikely to err, and that the non-sighting of the hilal is due to technical or natural factors. These results can serve as a reference for determining the start of the lunar month when the hilal is not visible due to cloudy conditions…”
Get full text

Ruxolitinib and oHSV combination therapy increases CD4 T cell activity and germinal center B cell populations in murine sarcoma by Ravi Dhital, Yeaseul Kim, Doyeon Kim, Ilse Hernandez-Aguirre, Jack Hedberg, Alexia Martin, Kevin A. Cassady

“…Here, we illustrate the utility of a high-dimensional spectral flow cytometry panel that permits simultaneous evaluation of intratumoral CD4/CD8 T cell, Treg, γδ-T cell, natural killer T (NKT) cell, B cell, NK cell, monocyte, macrophage, granulocyte, myeloid-derived suppressor cell (MDSC), and dendritic cell functional changes from RUX+oHSV-treated MPNSTs.…”
Get full text

Evaluation of the cardiotoxicity of Echinochrome A using human induced pluripotent stem cell-derived cardiac organoids by Su-Jin Lee, Eunji Kim, Yeeun Jeong, Jae Boum Youm, Hyoung Kyu Kim, Jin Han, Elena A. Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Sung Joon Kim, Hyang-Ae Lee

“…Echinochrome A (EchA), a marine-derived natural product, has shown promise in treating cardiovascular and inflammatory diseases due to its antioxidant and anti-inflammatory properties. …”
Get full text

تولية الكافر على المسلم في ولاية الحكم عند ابن تيمية by Ahmad Muqorobin, Ahmad Rayhan

“…From sight general the researchers take the essence of the kafir's leadership over a Muslim and a natural government . In order for the analysis to be accomplished more deeply, the author develops his analysis by using descriptive analysis techniques. …”
Get full text