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Is information provided within chronic subdural haematoma education resources adequate? A scoping review.
Published 2023-01-01“…Resources were classified into a hierarchical framework using inductive thematic analysis into 8 core domains: Aetiology, epidemiology and pathophysiology; natural history and risk factors; symptoms; diagnosis; surgical management; nonsurgical management; complications and recurrence; and outcomes. …”
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Gut-Heart Axis: Microbiome Involvement in Restrictive Cardiomyopathies
Published 2025-01-01“…An intriguing aspect of restrictive cardiomyopathies (RCM) is the microbiome role in the natural history of the disease. These cardiomyopathies are often difficult to diagnose and so result in significant morbidity and mortality. …”
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Camel tick species distribution in Saudi Arabia and United Arab Emirates using MaxEnt modelling
Published 2024-08-01Get full text
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Twelve barriers to COPD diagnosis in France: a comparative qualitative study
Published 2025-01-01“…Our qualitative study aimed to identify barriers to establishing diagnosis in the natural history of this condition.Methods An inductive thematic analysis was performed on structured interviews with patients, general practitioners (GPs) and pulmonologists in France. …”
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Modeling compositional heterogeneity resolves deep phylogeny of flowering plants
Published 2025-01-01Get full text
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Identification of a pathogenic founder variant in the WFS1 gene that causes Wolfram syndrome in the Druze population
Published 2025-01-01“…It is characterized by central diabetes insipidus, juvenile-onset diabetes mellitus (DM), optic atrophy (OA), and deafness. The natural history of WS is variable, even within the same family and with the same variant.ObjectiveTo report the phenotypes of five patients of Druze origin, all carrying the same autosomal recessive pathogenic variant in the WFS1 gene.Patients & methodsFive patients belonging to three core families were enrolled. …”
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Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study
Published 2022-06-01“…This study evaluated the cost-effectiveness of genotype-dependent and pan-genotypic DAA regimens in Iran as an example of a resource-limited setting.Methods A Markov model was developed to simulate HCV natural history. A decision tree was developed for HCV treatment, assuming four scenarios, including scenario 1: genotyping, sofosbuvir/ledipasvir (SOF/LDV) for genotype 1, and sofosbuvir/daclatasvir (SOF/DCV) for genotype 3; scenario 2: genotyping, SOF/LDV for genotype 1, and sofosbuvir/velpatasvir (SOF/VEL) for genotype 3; scenario 3: no genotyping and SOF/DCV for all; and scenario 4: no genotyping and SOF/VEL for all. …”
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Impact of a potential Chlamydia vaccine in the USA: mathematical modelling analyses
Published 2024-05-01“…The model’s parameters were chosen based on current knowledge from the literature on CT’s natural history and epidemiology. The model’s calibration used age-specific CT prevalence data sourced from the biannual rounds of the National Health and Nutrition Examination Surveys. …”
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Insulin Resistance and Chronic Kidney Disease in Patients with Type 1 Diabetes Mellitus
Published 2017-01-01“…Insulin resistance plays an important role in the natural history of type 1 diabetes. The purpose of the study was to determine the prevalence of CKD in T1DM and the correlation with insulin resistance (IR) in patients with CKD. …”
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