Showing 481 - 500 results of 544 for search '"natural history"', query time: 0.08s Refine Results
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    Is information provided within chronic subdural haematoma education resources adequate? A scoping review. by Conor S Gillespie, Samuel Khanna, Mark E Vivian, Samuel McKoy, Alvaro Yanez Touzet, Ellie Edlmann, Daniel J Stubbs, Benjamin M Davies

    Published 2023-01-01
    “…Resources were classified into a hierarchical framework using inductive thematic analysis into 8 core domains: Aetiology, epidemiology and pathophysiology; natural history and risk factors; symptoms; diagnosis; surgical management; nonsurgical management; complications and recurrence; and outcomes. …”
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    Gut-Heart Axis: Microbiome Involvement in Restrictive Cardiomyopathies by Samuel Jaimez-Alvarado, Itzel Ivonn López-Tenorio, Javier Barragán-De los Santos, Dannya Coral Bello-Vega, Francisco Javier Roldán Gómez, Amedeo Amedei, Enrique Alexander Berrios-Bárcenas, María Magdalena Aguirre-García

    Published 2025-01-01
    “…An intriguing aspect of restrictive cardiomyopathies (RCM) is the microbiome role in the natural history of the disease. These cardiomyopathies are often difficult to diagnose and so result in significant morbidity and mortality. …”
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    Twelve barriers to COPD diagnosis in France: a comparative qualitative study by Maxime Patout, Laurie Fraticelli, Maéva Zysman, Olivier Le Rouzic, Elisabetta Scanferla, Clémence Martin, Mathieu Delorme, Cécilia Nocent-Ejnaini, Guillaume Roucoux, Lize Kiakouama Maleka, Annaig Ozier, Yassine Benarbia, Lize Kiakouama, Olivier Le Rouzic, Jean-Paul Vasseur, Marie-Agnès Wiss-Laurent, Carla Zonca, Nissrine Erraji, Matthieu Chanard, Fabienne Peretz, Catherine Beseme, Antonio Correira Dos Santos, Héla Saïdi, Lynda Saïl

    Published 2025-01-01
    “…Our qualitative study aimed to identify barriers to establishing diagnosis in the natural history of this condition.Methods An inductive thematic analysis was performed on structured interviews with patients, general practitioners (GPs) and pulmonologists in France. …”
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    Identification of a pathogenic founder variant in the WFS1 gene that causes Wolfram syndrome in the Druze population by Inbal Halabi, Inbal Halabi, Yardena Tenenbaum-Rakover, Yardena Tenenbaum-Rakover, Lena Sagi-Dain, Lena Sagi-Dain, Lena Sagi-Dain, Ilana Koren, Ilana Koren, Ilana Koren

    Published 2025-01-01
    “…It is characterized by central diabetes insipidus, juvenile-onset diabetes mellitus (DM), optic atrophy (OA), and deafness. The natural history of WS is variable, even within the same family and with the same variant.ObjectiveTo report the phenotypes of five patients of Druze origin, all carrying the same autosomal recessive pathogenic variant in the WFS1 gene.Patients & methodsFive patients belonging to three core families were enrolled. …”
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  12. 492

    Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study by Seyed Moayed Alavian, Mohammad Tasavon Gholamhoseini, Heidar Sharafi, Helena HL Borba, Asma Sabermahani, Behzad Hajarizadeh

    Published 2022-06-01
    “…This study evaluated the cost-effectiveness of genotype-dependent and pan-genotypic DAA regimens in Iran as an example of a resource-limited setting.Methods A Markov model was developed to simulate HCV natural history. A decision tree was developed for HCV treatment, assuming four scenarios, including scenario 1: genotyping, sofosbuvir/ledipasvir (SOF/LDV) for genotype 1, and sofosbuvir/daclatasvir (SOF/DCV) for genotype 3; scenario 2: genotyping, SOF/LDV for genotype 1, and sofosbuvir/velpatasvir (SOF/VEL) for genotype 3; scenario 3: no genotyping and SOF/DCV for all; and scenario 4: no genotyping and SOF/VEL for all. …”
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    Impact of a potential Chlamydia vaccine in the USA: mathematical modelling analyses by Hiam Chemaitelly, Laith J Abu-Raddad, Houssein H Ayoub, Susanne F Awad, Monia Makhoul

    Published 2024-05-01
    “…The model’s parameters were chosen based on current knowledge from the literature on CT’s natural history and epidemiology. The model’s calibration used age-specific CT prevalence data sourced from the biannual rounds of the National Health and Nutrition Examination Surveys. …”
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    Insulin Resistance and Chronic Kidney Disease in Patients with Type 1 Diabetes Mellitus by Mihaela Vladu, Diana Clenciu, Ion Cristian Efrem, Mircea-Cătalin Forțofoiu, Anca Amzolini, Simona Tudorică Micu, Maria Moţa, Maria Forțofoiu

    Published 2017-01-01
    “…Insulin resistance plays an important role in the natural history of type 1 diabetes. The purpose of the study was to determine the prevalence of CKD in T1DM and the correlation with insulin resistance (IR) in patients with CKD. …”
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