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Cost–consequence analysis of COPD treatment according to NICE and GOLD recommendations compared with current clinical practice in the UK
Published 2022-06-01“…Objectives The objective of this study was to model the clinical and economic impact of adapting current clinical practice in the management of patients with chronic obstructive pulmonary disease (COPD) to treatment according to national and international guideline recommendations.Design Treatment mapping was undertaken to hypothetically redistribute patients from current clinical practice, representing actual prescribing patterns in the UK, to an alternative recommendation-based treatment scenario, representing prescribing in accordance with either National Institute for Health and Care Excellence (NICE) guidance [NG115] or Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020 strategy.Setting Primary care practices in the UK (1-year time horizon).Participants Adults with COPD undergoing long-acting inhaler maintenance therapy in the UK (N=1 067,531).Interventions Inhaler maintenance therapy.Outcome measures Costs and clinical outcomes (type of treatment, rates of moderate and/or severe exacerbations, and mild-to-moderate and/or severe pneumonia events) were modelled for the two alternative pathways.Results Compared with current clinical practice, treating patients according to NICE guidance resulted in an estimated annual reduction in expenditure of £46.9 million, and an estimated annual reduction in expenditure of over £43.7 million when patients were treated according to GOLD 2020 strategy. …”
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8262
Sharing information about domestic violence and abuse in healthcare: an analysis of English guidance and recommendations for good practice
Published 2022-06-01“…Documents were identified by searching websites of national bodies in England that guide and regulate clinical practice and by backwards citation-searching documents we identified initially.Results We found 13 documents that guide practice. …”
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Cluster randomised controlled trial of screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the pilot study for the SAFER trial
Published 2022-09-01“…Dissemination will be via publications, patient-friendly summaries, reports and engagement with the UK National Screening Committee.Trial registration number ISRCTN72104369.…”
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Depressive symptoms and overwork among physicians employed at a university hospital in Japan
Published 2017-11-01“…The extent of overwork among resident physicians employed at national university hospitals in Japan is unknown and needs to be investigated. …”
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Prevalence and features of allergic bronchopulmonary aspergillosis, United States, 2016-2022.
Published 2025-01-01“…The epidemiology of allergic bronchopulmonary aspergillosis (ABPA) in the United States is not well-described. To estimate national ABPA prevalence among patients with asthma or cystic fibrosis, characterize ABPA testing practices, and describe ABPA clinical features, treatment, and 6-month outcomes. …”
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Elevated resting heart rate in adolescent men and risk of heart failure and cardiomyopathy
Published 2020-06-01“…HF and its concomitant diagnoses, as well as all CM diagnoses, were collected from the national inpatient, outpatient, and cause of death registries. …”
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The riflemen union in the Independence war
Published 1998-12-01“… The Riflemen Union (RU) of Lithuania was established on the initiative expressed by the Military Intelligence of the Ministry of National Defence and Lithuanian intelligentsia. The purpose of the organization was to consolidate society for a struggle against the enemies of Lithuania. …”
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Clinical efficacy of 0.1% cyclosporine A in dry eye patients with inadequate responses to 0.05% cyclosporine A: a switching, prospective, open-label, multicenter study
Published 2025-01-01“…Objective signs of dry eye, including the National Eye Institute (NEI) score, tear film break-up time (TF-BUT), and tear volume also improved (p < 0.0001). …”
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Exploring rural households’ knowledge and perception of acute kidney injury in the southern region of The Gambia: a mixed-method community-based cross-sectional study design
Published 2024-07-01“…Background The Acute Kidney Injury (AKI) outbreak in The Gambia is a national tragedy attracting international concern, linked to nearly 100 deaths in children. …”
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Acceptance and affordability of malaria vaccines: issues relating to hesitancy and willingness to pay amongst Nigerian parents of under-five children
Published 2025-02-01“…This study adopted a proactive approach in assessing parents' acceptance of the malaria vaccine, alongside their willingness to pay for the novel public health intervention. Methods A national cross-sectional survey was undertaken in Nigeria using a questionnaire as the data collection instrument. …”
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Innovative Approaches to Ensuring Cybersecurity and Public Safety: The Socio-Economic Dimension
Published 2025-01-01“…The paper examines the impact of socio-economic development indicators, in particular gross national income, spending and remittances, literacy and unemployment, on the dynamics of cybercrime worldwide, and analyses trends in public awareness and involvement in criminal activity in the digital space. …”
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Metabolic Syndrome and Its Associated Factors among Type 2 Diabetic Patients in Southwest Ethiopia, 2021/2022
Published 2022-01-01“…The magnitude of metabolic syndrome was determined by using the National Cholesterol Education Program Third Adult Treatment Panel III criteria. …”
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8273
Transitioning health workers from PEPFAR contracts to the Uganda government payroll
Published 2021“…At the national level, multi-sectoral engagements (incorporating the influential Ministry of Finance), developing a joint transition road map, aligning with GoU salary scales and recruitment processes emerged as facilitators of the transition process. …”
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Leveraging Digital Twin Technology for Battery Management: A Case Study Review
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8280
Identification and Characterization of Sulfur Cake from Stepnogorsk Sulfuric Acid Plant
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