Cost-effectiveness Analysis of Radium-223 Dichloride in Metastatic Castration-Resistant Prostate Cancer Patients Without Previous Chemotherapy Treatment in Spain by Eva Tirado Mercier, Daniel Callejo Velasco, Marta Rubio Cabezas, Cristina Moretones Agut, Meritxell Granell Villalón

“…**Conclusions:** Although results must be assessed with caution, from the Spanish National Health System perspective and based on the results of the present analysis, radium-223 could be a suitable option of health resources’ utilization for end of life mCRPC without previous docetaxel treatment, subject to a moderate level of uncertainty.…”
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Coproducing healthcare service improvement for people with common mental health disorders including psychotic experiences: a study protocol of a multiperspective qualitative study by Alexandros Georgiadis, Robbie Duschinsky, Jesus Perez, Peter B Jones, Debra Russo, Clare Knight, Emma Soneson, Mary Dixon-Woods

“…Data analysis will be based on the constant comparative method.Ethics and dissemination The study has been approved by the London Harrow Research Ethics Committee (reference: 18/LO/0642), and all National Health Service Trusts have granted permissions to conduct the study. …”
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Health Benefits Due to Reduction in Respirable Particulates during COVID-19 Lockdown in India by Anubha Goel, Pallavi Saxena, Saurabh Sonwani, Shubham Rathi, Ananya Srivastava, Akash Kumar Bharti, Supreme Jain, Shubhanshi Singh, Anuradha Shukla, Anju Srivastava

“…PM2.5 concentrations in nonattainment cities (NACs) in Uttar Pradesh and the Delhi-National Capital Region (NCR) in North India were studied. …”
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Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study by Mengye Zhang, Hao Lin, Xue Xu

“…Methods This study involves a cross-sectional analysis on data from the National Health and Nutrition Examination Survey (NHANES) during the period from 2011 to 2014. …”
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Biomonitoring potential of trace metal accumulation and bioavailability in coral skeletons and reef sediments of Persian Gulf: A comparative study by Seyed Hassan Mousavi, Mehdi Gholamalifard, Seyed Mahmoud Ghasempouri

“…Nayband Marine National Park in the northern Persian Gulf is an important ecological areas, significantly impacted by industrial activites that poses risk of trace metal pollution to living organisms. …”
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The theoretical cognition and research paradigm of land system science by LONG Hualou, CHEN Kunqiu, ZHENG Yuhan, ZHANG Yingnan

“…The needs of national strategies, the dilemmas of urban-rural development and the shortcomings in disciplinary development put urgent requirement for the establishment of land system science. …”
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Trend of skin cancer mortality and years of life lost in China from 2013 to 2021 by Jingyi Li, Jiaqi Zeng, Yuanchao Yang, Biran Huang

“…This study aimed to estimate the mortality trends of skin cancer in China within 2013–2021.MethodsA retrospective analysis of skin cancer deaths within 2013–2021 was performed using the China death cause surveillance dataset compiled by the National Health Commission Statistics Information Center and the China Center for Disease Control and Prevention Chronic Non-Communicable Diseases Prevention and Control Center. …”
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Cost Analysis of the Use of Voriconazole, Posaconazole and Micafungin in the Primary Prophylaxis of Invasive Fungal Infections in Recipients of Allogeneic Hematopoietic Stem Cell T... by Santiago Grau, Carlos Solano, Carol García-Vidal, Isidro Jarque, Jon A. Barrueta, Carmen Peral, Irene Rodríguez, Darío Rubio-Rodríguez, Carlos Rubio-Terrés

“…**Objectives:** Compare the cost of the primary prophylaxis of invasive fungal infections (IFI) with voriconazole, posaconazole, and micafungin in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) in hospitals of the National Health System (NHS) in Spain. **Methods:** A cost analysis was made for 100 days and 180 days of prophylaxis and a decision tree model was developed. …”
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Challenges in exercising the right to annual leave for workers on long-term sick leave in the Republic of Croatia by Bjelić-Gaćeša Dragana

“…As such, it is incorporated in a number of legal acts, both at the international and regional, as well as at the national levels. The purpose of this right is to enable the workers to rest from physical and/or mental work, to enable them to enjoy relaxation and leisure in order to restore their working abilities. …”
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Factors that influence the feasibility and implementation of a complex intervention to improve the treatment of peripheral arterial disease in primary and secondary care: a qualita... by Athanasios Saratzis, Vanessa Lawrence, Ruth Benson, Emma Watson, Prakash Saha, Clair Le Boutillier, Bernadeta Bridgwood

“…Objectives Our aim was to examine the feasibility and implementation of a complex intervention to improve the care of patients with peripheral arterial disease (the LEGS intervention) from the perspective of patients, general practitioners and secondary care clinicians.Design A qualitative study involving semistructured individual interviews with patients and providers to gain an understanding of the feasibility of the LEGS intervention as well the barriers and facilitators to implementation in secondary and primary care.Setting Primary and secondary care settings across two National Health Service Trusts.Participants Twenty-five semistructured telephone interviews were conducted with (1) patients who had received the intervention (n=11), (2) secondary care clinicians responsible for delivering the intervention (n=8) and (3) general practitioners (n=6).Analysis Data were initially analysed using inductive descriptive thematic analysis. …”
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Pembentukan Perda Berbasis Syari’ah dalam Bingkai Negara Hukum Pancasila by Thomas Febria, Dendi Kurniawan

“…Sociologically, the cultural pluralism of the Indonesian nation is always related to religion. Juridically, the provisions in Article 10 paragraph (1) letter f of Constitution Number 23 of 2014 concerning Regional Government have been amended several times, most recently by Law Number 11 of 2020 concerning Job Creation and their explanations. …”
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ACCESSING FINANCE FOR INNOVATIVE EU SMES – KEY DRIVERS AND CHALLENGES by Laura Vasilescu

“…In order to improve the access to finance for SMEs, the efforts should be focused at the European and national levels on solving the problems regarding working capital, improving entrepreneurship and financial environment in the long term, attracting new financial resources, facilitating dialogue and consultation between governments, SMEs and financial institutions. …”
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A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer by Yu Xiaoqian, Hu Jiwei, Zhou Lizhi, Guo Baojia, Guo Luyan, Xu Huiqian, Li Hong, Fan Yijing

“…Methods: Overall, 108 patients with peripheral neuropathy after chemotherapy for breast cancer were randomly divided into the control group (routine nursing), experimental group 1 (compression therapy), and experimental group 2 (compression therapy and EXCAP). The National Institute of Cancer Drug Toxicity Rating Scale and the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool were assessed and compared between groups. …”
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Evaluating ChatGPT-4's performance on oral and maxillofacial queries: Chain of Thought and standard method by Kaiyuan Ji, Zhihan Wu, Jing Han, Guangtao Zhai, Guangtao Zhai, Jiannan Liu

“…This study evaluated the performance of ChatGPT-4 in addressing oral and maxillofacial disease questions using standard approaches and the Chain of Thought (CoT) method, aiming to gain a deeper understanding of its capabilities, potential, and limitations.Materials and methodsThree experts, drawing from their extensive experience and the most common questions in clinical settings, selected 130 open-ended questions and 1,805 multiple-choice questions from the national dental licensing examination. These questions encompass 12 areas of oral and maxillofacial surgery, including Prosthodontics, Pediatric Dentistry, Maxillofacial Tumors and Salivary Gland Diseases, and maxillofacial Infections.ResultsUsing CoT approach, ChatGPT-4 exhibited marked enhancements in accuracy, structure, completeness, professionalism, and overall impression for open-ended questions, revealing statistically significant differences compared to its performance on general oral and maxillofacial inquiries. …”
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Predicting the risk of cardiovascular disease in adults exposed to heavy metals: Interpretable machine learning by Meiyue Shen, Yine Zhang, Runqing Zhan, Tingwei Du, Peixuan Shen, Xiaochuan Lu, Shengnan Liu, Rongrong Guo, Xiaoli Shen

“…We aimed to construct an interpretable machine learning model utilizing National Health and Nutrition Examination Survey data to investigate the relationship between heavy metal exposure and cardiovascular disease (CVD). …”
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The distribution, phenology, host range and pathogen prevalence of Ixodes ricinus in France: a systematic map and narrative review by Perez, Grégoire, Bournez, Laure, Boulanger, Nathalie, Fite, Johanna, Livoreil, Barbara, McCoy, Karen D., Quillery, Elsa, René-Martellet, Magalie, Bonnet, Sarah I.

“…Understanding its distribution, phenology, and host species use, along with the distribution and prevalence of associated pathogens at a national scale is essential for developing prevention strategies. …”
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Security Challenges: Appraisal of Threats to Nigeria’s Sovereignty in the Fourth Republic (1999-2019) by Olanrewaju Rafiu Memud, Solomon A. Ojo

“…The study concludes that emergence of popularly elected action-centered or functional leadershipwith good economic development blueprintand national integration strategies can reduce identified insecurity issues. …”
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Impact of COVID-19 Event on the Air Quality in Iran by Parya Broomandi, Ferhat Karaca, Amirhossein Nikfal, Ali Jahanbakhshi, Mahsa Tamjidi, Jong Ryeol Kim

“…Conversely, O3 and PM2.5 increased by 0.5–103% and 2–50%. In terms of the national air quality, SO2 and NO2 levels decreased while AOD increased during the lockdown. …”
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Antimicrobial use regulations are associated with increased susceptibility among bovine Salmonella isolates from a U.S. surveillance system by Claudia Cobo-Angel, Maya Craig, Marwan Osman, Kevin J. Cummings, Casey L. Cazer

“…This study aimed to assess the impact of the 2012 and 2017 regulations on antimicrobial use in cattle in the United States by analyzing 18,627 bovine Salmonella AMR susceptibility patterns using data from the National Antimicrobial Resistance Monitoring System (NARMS). …”
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“When you provide abortion services, you are looked upon as a bad guy”: experiences of abortion stigma by health providers in Nigeria by Friday Okonofua, Lorretta Ntoimo, Louise Bury, Suzanna Bright, Lesley Hoggart

“…Participants attributed stigma to cultural and religious beliefs, the restrictive national abortion law, and pointed to hypocrisy. Some reported effects of stigma on providers included a feeling of insecurity, social exclusion, secrecy, and insincerity in clinical practice, discouragement, and guilt feelings. …”
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