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2921
A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus
Published 2025-02-01“…In this study, we explored an mRNA vaccine based on a modified pre-F protein called LC2DM-lipid nanoparticle (LC2DM-LNP). This vaccine features a truncated version of the pre-F protein that is anchored to the cell membrane. …”
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2922
THE EFFECT OF ZNO/CUO-WATER- HYBRID NANOFLUID CONCENTRATION RATIO ON HEAT TRANSFER CHARACTERISTICS IN ELECTRONIC EQUIPMENT COOLING SYSTEMS
Published 2025-01-01“…At a particular configuration of flowrate and nanoparticle ratio, the hybrid nanofluid has more than 2.5 times higher coefficient of convection than distilled water. …”
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2923
Is Breath Best? A Systematic Review on the Accuracy and Utility of Nanotechnology Based Breath Analysis of Ketones in Type 1 Diabetes
Published 2025-01-01“…A comprehensive search across 5 databases identified 11 studies meeting inclusion criteria, showcasing various breath analysis techniques, such as semiconducting gas sensors, colorimetry, and nanoparticle-based chemo-resistive sensors. These studies report high sensitivity and correlation between breath acetone (BrAce) levels and blood ketones, with some demonstrating accuracies up to 94.7% and correlations reaching R<sup>2</sup> values as high as 0.98. …”
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2924
Numerical simulation of rotating flow of CNT nanofluids with thermal radiation, ohmic heating, and autocatalytic chemical reactions
Published 2025-02-01“…The repercussions of flow factors on velocity, temperature, nanoparticle concentration, skin friction coefficients, and local Nusselt number are provided via tables and graphs. …”
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2925
Investigation of the anti-aging effects of active components of Artemia franciscana loaded in hyalurosome
Published 2025-01-01“…The physicochemical properties of the hyalurosomes were characterized, revealing nanoparticle sizes ranging from 100 to 130 nm, zeta potential between − 57 and − 41.2 mV. …”
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2926
A cGAMP‐Containing Hydrogel for Prolonged SARS‐CoV‐2 Receptor‐Binding Domain Subunit Vaccine Exposure Induces a Broad and Potent Humoral Response
Published 2025-01-01“…Specifically, through coencapsulation of cGAMP and RBD in an injectable polymer‐nanoparticle (PNP) hydrogel, the cGAMP‐adjuvanted hydrogel vaccine elicits more potent, durable, and broad antibody responses with improved neutralization as compared to dose‐matched bolus controls and hydrogel‐based vaccines lacking cGAMP. …”
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2927
Computational analysis of thermo-solutal Marangoni convective unsteady stagnation point flow of tetra hybrid nanofluid past rotating sphere with activation energy
Published 2025-01-01“…Thermal distribution and rate of heat transfer improve but concentration distribution declines as nanoparticle volume friction rises.…”
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2928
Mucosal immune response in biology, disease prevention and treatment
Published 2025-01-01“…Innovative therapies, such as nanoparticle vaccines and inhalable antibodies, show promise in enhancing mucosal immunity and offer potential for improved disease prevention and treatment.…”
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2929
Highly Sensitive Amperometric α-Ketoglutarate Biosensor Based on Reduced Graphene Oxide-Gold Nanocomposites
Published 2020-01-01“…Herein, a rapid and highly sensitive amperometric biosensor for the detection of α-ketoglutarate (α-KG) was constructed via an electrochemical approach, in which the glutamate dehydrogenase (GLUD) was modified on the surface of reduced graphene oxide-gold nanoparticle composite (rGO-Aunano composite). The rGO-Aunano composite was one-step electrodeposited onto glassy carbon electrode (GCE) surface and was characterized by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), and electrochemical techniques. …”
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2930
Navigating the frontier: Comprehensive insights into CRISPR technology advancements, delivery strategies, and ethical considerations in cancer research
Published 2024-03-01“…A significant portion of the review is dedicated to the integration of nanotechnology with CRISPR for cancer treatment, discussing nanoparticle systems and their effectiveness in enhancing delivery precision. …”
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2931
Heat Transfer Enhancement of Laminar Nanofluids Flow in a Circular Tube Fitted with Parabolic-Cut Twisted Tape Inserts
Published 2014-01-01“…The results also revealed that the heat transfer enhancement increases with an increase in the volume fraction of the CuO nanoparticle. Furthermore, the twisted tape with twist ratio (y = 2.93) and cut depth w = 0.5 cm offered 10% enhancement of the average Nusselt number with significant increases in friction factor than those of Classical twisted tape.…”
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2932
Nanocomposites of various shapes in trihybrid nanofluid flow past a Riga plate with electroosmotic effects
Published 2025-02-01“…Thermal distribution under the impacts of Lorentz forces is examined graphically for ternary nanofluid with carbon nanotubes as nanoparticle in spherical shape, Al2O3in platelet shape and graphene nano particles in cylindrical shape over the convectively heated Riga plate. …”
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2933
Phenolic compounds and biological activities of grape (Vitis vinifera L.) seeds at different ripening stages: insights from Algerian varieties
Published 2025-01-01“…Antioxidant activities were assessed via (DPPH), (ABTS), phenanthroline, reducing power, and silver nanoparticle assays. Additionally, anti-tyrosinase activity and photoprotective effects were evaluated. …”
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2934
Sulforaphane in alternative cancer chemotherapy: From carcinogenesis suppression to drug resistance reversal
Published 2025-01-01“…In conclusion, SFN shows significant promise in cancer therapy by targeting multiple molecular pathways, improving the efficacy of chemotherapy, and overcoming drug resistance, particularly when incorporated into advanced nanoparticle delivery systems.…”
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2935
Conductive Composite Biosensor System for Electrochemical Indinavir Drug Detection
Published 2015-01-01“…The biosensor platform consisted of CYP3A4 immobilized onto a gold nanoparticle (GNP) overoxidized polypyrrole (OvOxPpy) carrier matrix. …”
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2936
Plasma-derived exosomal miR-326, a prognostic biomarker and novel candidate for treatment of drug resistant pediatric acute lymphoblastic leukemia
Published 2024-01-01“…Exosomes were isolated from plasma samples of 30 patients and B-ALL cell lines followed by characterization, using nanoparticle tracking analysis, immunoblotting assay and electron microscopy. qPCR showed significantly increased levels of miR-326 in patients exosomes compared with non-cancer controls (P < 0.05, AUC = 0.7500). …”
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2937
Machine learning-driven analysis of heat transfer in chemically reactive fluid flow considering Soret-Dufour effects
Published 2025-01-01“…Objective: The study investigates tangent hyperbolic nanofluid flow across an extended media, emphasizing magnetohydrodynamic influences, mixed convection, and nanoparticle transport with the help of an innovative and advanced technique. …”
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2938
Global scenario of silica-associated diseases: A review on emerging pathophysiology of silicosis and potential therapeutic regimes
Published 2025-06-01“…In recent periods, a lot of attention has been focused on the development and fabrication of suitable nanocarriers for improved and sustained drug delivery in the pulmonary system. Nanoparticle-based therapeutic modality has been evaluated in in-vitro and ex-vivo silicosis models for prolongation of drug activity and improved therapeutic outcomes. …”
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2939
Inhibitory effects of cadmium and hydrophilic cadmium telluride quantum dots on the white rot fungus Phanerochaete velutina
Published 2025-01-01“…The different EC50 values indicate that the nanoparticle coatings have a strong influence on the inhibitory effects, as the organic ligands used for surface passivation prevented the leaching of acute toxic Cd ions from the metallic QD core. …”
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2940
High-Affinity Detection of Alpha-Synuclein by Aptamer-Gold Conjugates on an Amine-Modified Dielectric Surface
Published 2019-01-01“…In addition, a gold nanoparticle-conjugated aptamer was used to enhance the detection limit. …”
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