HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients by Floran Begue, Bryan Veeren, Philippe Rondeau, Aline-Marie Florence, Simon Jamard, Philippe Montravers, Sébastien Tanaka, Olivier Meilhac, on behalf of French COVID Study Group

“…Despite the crucial role that these nanoparticles play in SARS-CoV-2 infection, few studies have examined their structure during COVID-19 beyond HDL quantity. …”
Get full text

An ATP-activated spatiotemporally controlled hydrogel prodrug system for treating multidrug-resistant bacteria-infected pressure ulcers by Xiaoliang Qi, Yajing Xiang, Ying Li, Jiajia Wang, Yuxi Chen, Yulong Lan, Jinsong Liu, Jianliang Shen

“…Herein, we present an endogenous ATP-activated prodrug system (termed ISD3) consisting of nanoparticles (indole-3-acetic acid/zeolitic imidazolate framework-8@polydopamine@platinum, IZPP) embedded in a silk fibroin-based hydrogel, aimed at treating multidrug-resistant (MDR) bacteria-infected pressure ulcers. …”
Get full text

GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia by Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H

“…However, there have been no reports on its efficacy in treating limb ischemia through promoting angiogenesis.Materials and Methods: In this study, we prepared AST-loaded lignin nanoparticles (LNP/AST) with sustained-release functionality, which were mixed with GelMA hydrogel (GelMA@LNP/AST). …”
Get full text

Unraveling the laser decal transfer-based printing of ZnO ceramic towards FEP-ZnO-based Piezo-Tribo hybrid nanogenerators by Arpit Kumar Singh, Anshu Sahu, Palani Iyamperumal Anand

“…The selectively transferred nanoparticles in various patterns are further grown using a hydrothermal technique. …”
Get full text

Lipid Coating Modulates Effects of Nanoceria on Oxidative Metabolism in Human Embryonic Lung Fibroblasts: A Case of Cardiolipin by Elena V. Proskurnina, Madina M. Sozarukova, Elizaveta S. Ershova, Ekaterina A. Savinova, Larisa V. Kameneva, Natalia N. Veiko, Maria A. Teplonogova, Vladimir P. Saprykin, Vladimir K. Ivanov, Svetlana V. Kostyuk

“…Lipid modifiers of the nanoparticle surface change their biochemical properties and bioavailability. …”
Get full text

A synthetic cyclic peptide for promoting antigen presentation and immune activation by Jiahui Zhang, Harrison Y. R. Madge, Asmaa Mahmoud, Lantian Lu, Wanyi Wang, Wenbin Huang, Prashamsa Koirala, Jazmina L. Gonzalez Cruz, Wei Yang Kong, Sahra Bashiri, Ahmed O. Shalash, Waleed M. Hussein, Zeinab G. Khalil, James W. Wells, Istvan Toth, Rachel J. Stephenson

“…All vaccine candidates self-assembled into sub-500 nm nanoparticles and induced high antigen-specific systemic IgG titers and opsonic potential compared to the antigen co-administered with a commercial adjuvant, complete Freund’s adjuvant. …”
Get full text

Advanced Amperometric Microsensors for the Electrochemical Quantification of Quercetin in <i>Ginkgo biloba</i> Essential Oil from Regenerative Farming Practices by Elena Oancea, Ioana Adina Tula, Gabriela Stanciu, Raluca-Ioana Ștefan-van Staden, Jacobus (Koos) Frederick van Staden, Magdalena Mititelu

“…The sensor configurations utilized two forms of carbon material as a foundation: graphite (G) and carbon nanoparticles (CNs). These base materials were modified with paraffin oil, chitosan (CHIT), and cobalt(II) tetraphenylporphyrin (Co(II)TPP) to enhance sensitivity. …”
Get full text

Numerical assessment of heat transfer and entropy generation of a mixed convection ferrofluid flow under the effect of a non-uniform magnetic field by Kamel Zitouni, Messaouda Boumaaza, Lakhdar Aidaoui, Yahia Lasbet, Houssam Eddin Abdellatif, Shan Ali Khan, Yazid Chetbani, Ahmed Belaadi, Ibrahim M.H. Alshaikh, Djamel Ghernaout

“…., the Grashof number (Gr) (40 ≤ Gr ≤ 4 × 105), the Hartmann number (Ha) ranged from 0 to 50, Reynolds number (Re = 200) and volume fraction of Fe3O4 nanoparticles (Ø = 0.02). The effect of the various factors in the problem on heat transfer presented by Nusselt number (Nu) and the friction coefficient along the entropy generation have been discussed graphically. …”
Get full text

PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors by Lan Zou, Rujing Wang, Mengnan Zhao, Yuke Li, Chen Sun, Jinjin Xie, Yan Chen, Qian Jing, Dandan Mi, Sanjun Shi

“…In this study, we took a deliberate approach devoid of any chemical alterations to develop a novel photosensitizer called “pharmaceutical-dots (pharm-dots)” by combining nonemissive polymers (Poly (lactic-co-glycolic acid), PLGA) with nonfluorescent invisible molecules like curcumin, berberine, oridonin into PLGA nanoparticles (PLGA-NPs). Initially, our research commenced with a comprehensive mechanistic comparison study, consolidating fragmented information on optical mechanisms. …”
Get full text

Harnessing the Dual photocatalytic and electrochemical capabilities of pure and Ni-Doped MgO nanostructures for diclofenac detection by V. Bhoomika, K.T. Monalisa, Syed Khasim, T.M. Sharanakuamr, C.R. Ravikumar, N. Basavaraju, T.R. Shashi Shekhar, H.C. Ananda Murthy, K.U. Aravind

“…The average energy gap (Eg) value of NiO doped MgONPs(Ni:MgONPs)was found to be 4.29 eV.The preparedNi:MgONPsexhibited good electrochemical characteristics. These nanoparticles were successfully used for the detection of diclofenac molecule using the modified graphite electrodes with 0.1 N HCl as an electrolyte.The results shows an oxidation peak at 0.19 V before diclofenac was added, later it is migrated significantly towards the positive potential (0.07 V) after diclofenac was added. …”
Get full text

Evaluation of the antidiabetic and antinephritic effects of Pueraria tuberosa and Pterocarpus santalinus extracts co-encapsulated in nanostructured lipid carriers in streptozotocin... by Gyamcho Tshering Bhutia, Asit Kumar De, Manas Bhowmik, Pavia Bera, Tanmoy Bera

“…Animals were sacrificed for histopathological and biochemical analysis after eight weeks of therapy. Nanoparticles were characterized by their morphology, zeta potential, drug loading capacity, particle size, and release profile. …”
Get full text

Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering by Marshall S. Padilla, Kaitlin Mrksich, Yiming Wang, Rebecca M. Haley, Jacqueline J. Li, Emily L. Han, Rakan El-Mayta, Emily H. Kim, Sofia Dias, Ningqiang Gong, Sridatta V. Teerdhala, Xuexiang Han, Vivek Chowdhary, Lulu Xue, Zain Siddiqui, Hannah M. Yamagata, Dongyoon Kim, Il-Chul Yoon, James M. Wilson, Ravi Radhakrishnan, Michael J. Mitchell

“…Abstract Lipid nanoparticles (LNPs) are the preeminent non-viral drug delivery vehicle for mRNA-based therapies. …”
Get full text

DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge by Victoria Gnazzo, Hanaa Saleh, Ítalo A. Castro, Adrianus C. M. Boon, Amelia K. Pinto, James D. Brien, Carolina B. López

“…DDO268 when co-packaged with mRNA in lipid nanoparticles is sensed by RIG I-like receptors and safely induces local type I interferon (IFN) production followed by dendritic cells type 1 activation and migration to the draining lymph nodes. …”
Get full text

Preparation of an Intelligent pH Film Based on Biodegradable Polymers for Monitoring the Food Quality and Reducing the Microbial Contaminants by Kumaran Subramanian, Deivasigamani Balaraman, Kumaravel Kaliyaperumal, V. Devi Rajeswari, K. Balakrishnan, P. Ronald Ross, Elumalai Perumal, Pugazhvendan Sampath Renuga, Mani Panangal, Y. Swarnalatha, S. Velmurugan

“…Hydrogel comes in a variety of physical shapes, including slabs, microparticles, nanoparticles, coatings, and films. Due to its ease of manufacture and self-application in clinical and fundamental applications, hydrogel has been widely exploited as a drug carrier. …”
Get full text

Composites Based on Poly(ortho-toluidine) and WS₂ Sheets for Applications in the Supercapacitor Field by Teodora Burlanescu, Ion Smaranda, Andreea Androne, Cristina Stefania Florica, Madalina Cercel, Mirela Paraschiv, Adelina Udrescu, Adam Lőrinczi, Petru Palade, Andrei Galatanu, Catalin Negrila, Elena Matei, Monica Dinescu, Radu Cercel, Mihaela Baibarac

“…In this work, three methods for the synthesis of composites based on poly(ortho-toluidine) (POT) and WS₂ are reported: (a) the solid-state interaction (SSI) of POT with WS₂ nanoparticles (NPs); (b) the in situ chemical polymerization (ICP) of ortho-toluidine (OT); and (c) the electrochemical polymerization (ECP) of OT. …”
Get full text

Evaluation of Airborne Particulate Matter and Volatile Organic Compounds Released by Three Types of Mosquito Repellents by Soyeon Lee, Jongmin Park, Myoungho Lee, Minjung Kim, Boowook Kim, Kiyoung Lee, Kyungduk Zoh, Chungsik Yoon

“…However, the percentage of nanoparticles was highest in the liquid-type (50%), followed by the mat (46%) and coil-types (33%) (p < 0.05). …”
Get full text

Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review by Irfan Anjum, Ayesha Nasir, Faiza Naseer, Faiza Naseer, Ahsan Ibrahim, Bisma Rehman, Fawad Bashir, Qura Tul Ain

“…The coupling of phytotherapy with novel drug delivery systems such as nanoparticles, liposomes, nanotubes, quantum dots, etc. can help translate these beneficial effects of phytochemicals into clinical practice. …”
Get full text

Enhanced Photodecomposition of Methylene Blue in Water with Sr1−xKxTiO3−δ@PC-polyHIPEs under UV and Visible Light by Yonghua Gao, Tao Zhang, Qipeng Guo, Lizhen Gao

“…Sr1-xKxTiO3-δ (x = 0–0.5) nanoparticles were incorporated and adhered to PC-polyHIPEs to form Sr1-xKxTiO3-δ@PC-polyHIPEs for the first time. …”
Get full text

Evaluation of a PCR-based lateral flow device for detecting Aspergillus and Candida species from clinical specimens by Ariff Khalid, Jacinta Santhanam, Mohd Nizam Tzar, Ang-Lim Chua, Sharifah Fadilah Abdul Wahid, Wan Rahiza Wan Mat, Raha Abd Rahman, Petrick Periyasamy

“…The LFA dipstick, in a modified sandwich format, utilises immobilised antibodies complementary to the fluorophore labels on the PCR products, and gold nanoparticles to form a visible red line that indicates the presence of the targeted fungus. …”
Get full text

Functional nanocrystal as effective contrast agents for dual-mode imaging: Live-cell sonoluminescence and contrast-enhanced echography by V. Vighetto, E. Pascucci, N.M. Percivalle, A. Troia, K.M. Meiburger, M.R.P. van den Broek, T. Segers, V. Cauda

“…A prolonged over time and bright imaging effect is observed when adopting the developed nanoparticles. Furthermore, their nanometric size and potential targeting with biomolecules would allow ease extravasation and tissue or even cell penetration, achieving enhanced-contrast imaging. …”
Get full text