Nanobodies: From Discovery to AI-Driven Design by Haoran Zhu, Yu Ding

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Computational nanobody design through deep generative modeling and epitope landscape profiling by Liyun Huo, Tian Tian, Yanqin Xu, Qin Qin, Xinyi Jiang, Qiang Huang

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A nanobody-based blocking enzyme-linked immunosorbent assay for detecting antibodies against pseudorabies virus glycoprotein E by Huanhuan Lü, Pinpin Ji, Siyu Liu, Ziwei Zhang, Lei Wang, Yani Sun, Baoyuan Liu, Lizhen Wang, Qin Zhao

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AI-enabled alkaline-resistant evolution of protein to apply in mass production by Liqi Kang, Banghao Wu, Bingxin Zhou, Pan Tan, Yun (Kenneth) Kang, Yongzhen Yan, Yi Zong, Shuang Li, Zhuo Liu, Liang Hong

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Development of potent humanized TNFα inhibitory nanobodies for therapeutic applications in TNFα-mediated diseases by Tao Yin, Aubin Ramon, Matthew Greenig, Pietro Sormanni, Luciano D’Adamio

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Recombinant PASylated nanobody probes with improved blood circulation and tumor targeting by Yicheng Yang, Lingyue Jin, You Zhang, Siyu Zhou, Weijun Wei, Gang Huang, Changfeng Wu

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Generation of nanobodies against the F protein of respiratory syncytial virus and establishment of an indirect immunofluorescence assay by Qianqian Wang, Dongxiang Hong, Entao Li, Zekai Cheng, Jiachen Zhang, Tengchuan Jin, Sandra Chiu

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Small but Mighty: Nanobodies in the Fight Against Infectious Diseases by Wenning Jiang, Chundong Huang, Serge Muyldermans, Lingyun Jia

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Generation of Site‐Specifically Labeled Affinity Reagents via Use of a Self‐Labeling Single Domain Antibody by Stanley Fayn, Swarnali Roy, Chino C. Cabalteja, Woonghee Lee, Hima Makala, Kwamena Baidoo, Divya Nambiar, Julia Sheehan‐Klenk, Joon‐Yong Chung, Jesse Buffington, Mitchell Ho, Freddy E. Escorcia, Ross W. Cheloha

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Nanobody-Based Immunoassays for the Detection of Food Hazards—A Review by Wenkai Li, Zhihao Xu, Qiyi He, Junkang Pan, Yijia Zhang, El-Sayed A. El-Sheikh, Bruce D. Hammock, Dongyang Li

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GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

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A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies by Thomas Balligand, Claire Carpenet, Sergi Olivé Palau, Tom Jaspers, Pavana Suresh, Xin Liu, Himadri Medhi, Yoon Ho Lee, Mohammad Rashidian, Bart De Strooper, Hidde L Ploegh, Maarten Dewilde

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Research Progress on the Application of Neutralizing Nanobodies in the Prevention and Treatment of Viral Infections by Qingling Duan, Tong Ai, Yingying Ma, Ruoyu Li, Hanlin Jin, Xingyi Chen, Rui Zhang, Kunlu Bao, Qi Chen

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EvoNB: A protein language model-based workflow for nanobody mutation prediction and optimization by Danyang Xiong, Yongfan Ming, Yuting Li, Shuhan Li, Kexin Chen, Jinfeng Liu, Lili Duan, Honglin Li, Min Li, Xiao He

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Polyethyleneimine-polyethylene glycol copolymer targeted by anti-HER2 nanobody for specific delivery of transcriptionally targeted tBid containing construct by Batoul Saqafi, Fatemeh Rahbarizadeh

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Nanobodies targeting the tumor microenvironment and their formulation as nanomedicines by Liudmyla Maksymova, Yannick A. Pilger, Lutz Nuhn, Jo A. Van Ginderachter

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Applications and challenges in designing VHH-based bispecific antibodies: leveraging machine learning solutions by Michael Mullin, James McClory, Winston Haynes, Justin Grace, Nathan Robertson, Gino van Heeke

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Modular DNA barcoding of nanobodies enables multiplexed in situ protein imaging and high-throughput biomolecule detection by Shilin Zhong, Ruiyu Wang, Xinwei Gao, Qingchun Guo, Rui Lin, Minmin Luo

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Phage-displayed synthetic library and screening platform for nanobody discovery by Baolong Xia, Ah-Ram Kim, Feimei Liu, Myeonghoon Han, Emily Stoneburner, Stephanie Makdissi, Francesca Di Cara, Stephanie E Mohr, Aaron Ring, Norbert Perrimon

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Interleukin 21-Armed EGFR-VHH-CAR-T Cell Therapy for the Treatment of Esophageal Squamous Cell Carcinoma by Chenglin Zhang, Yanyan Liu, Haoran Guo, Ying Peng, Lei Huang, Shuangshuang Lu, Zhimin Wang

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