Combination of Hotspot Mutations With Methylation and Fragmentomic Profiles to Enhance Multi‐Cancer Early Detection by Thi Hue Hanh Nguyen, Giang Hoang Vu, Tu Thi Nguyen, Tuan Anh Nguyen, Vu Uyen Tran, Luyen Thi Vu, Giang Thi Huong Nguyen, Nhat Duy Nguyen, Trung Hieu Tran, Van Thien Chi Nguyen, Thanh Dat Nguyen, Trong Hieu Nguyen, Dac Ho Vo, Thi Tuong Vi Van, Thanh Thi Do, Minh Phong Le, Le Anh Khoa Huynh, Duy Sinh Nguyen, Hung Sang Tang, Hoai‐Nghia Nguyen, Minh‐Duy Phan, Hoa Giang, Lan N. Tu, Le Son Tran

“…Method A targeted amplicon sequencing approach was developed to profile 700 hotspot mutations in cell‐free DNA and integrated into the SPOT‐MAS assay, creating a single‐blood draw workflow. This workflow, namely SPOT‐MAS Plus was retrospectively validated in a cohort of 255 non‐metastatic cancer patients (breast, colorectal, gastric, liver, and lung) and 304 healthy individuals. …”
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The optimal neoadjuvant treatment strategy for HR+/HER2 + breast cancer: a network meta-analysis by Shiwei Liu, Miao Yu, Exian Mou, Meihua Wang, Shuanghua Liu, Li Xia, Hui Li, Hao Tang, Yajing Feng, Xin Yu, Kun Mi, Hao Wang

“…In pCR analysis, three neoadjuvant regimens sequentially ranked at the top, namely those comprising T-DM1, pertuzumab with trastuzumab, and tyrosine kinase inhibitor with trastuzumab, demonstrating significantly higher pCR rates than monotherapies. …”
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MultiTax-human: an extensive and high-resolution human-related full-length 16S rRNA reference database and taxonomy by Zhiwei Bao, Bin Zhang, Jianhua Yao, Ming D. Li

“…In this study, we developed an automatic system, named MultiTax pipeline, for generating de novo taxonomy from full-length 16S rRNA sequences using the Genome Taxonomy Database and other existing reference databases. …”
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Synthesis and characterization of zinc oxide nanoparticles-carbon composite derived from pineapple peel wastes for adsorption of methylene blue from solution and photocatalytic act... by Salsa Putri Alzura, Vienna Saraswaty, Safri Ishmayana, Yudha Prawira Budiman, Diana Rakhmawaty Eddy, Evyka Setya Aji, Diah Ratnaningrum, Een Sri Endah, Hanny Meirinawati, Henry Setiyanto

“…In this work, a biosorbent derived from pineapple peels and modified with zinc oxide nanoparticles namely ZnONPs/PPWB, was prepared for the removal of cationic dyes, specifically methylene blue (MB), from aqueous solution. …”
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Multi-task aquatic toxicity prediction model based on multi-level features fusion by Xin Yang, Jianqiang Sun, Bingyu Jin, Yuer Lu, Jinyan Cheng, Jiaju Jiang, Qi Zhao, Jianwei Shuai

“…Furthermore, to validate the advantages of multi-task learning, we independently construct prediction models, named ATFPGT-single, for each fish species. We employ cross-validation in our experiments to assess the performance and generalization ability of ATFPGT-multi. …”
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Six new species of zombie-ant fungi from Yunnan in China by Dexiang Tang, Ou Huang, Weiqiu Zou, Yuanbing Wang, Yao Wang, Quanying Dong, Tao Sun, Gang Yang, Hong Yu

“…Six novel species of Ophiocordyceps with hirsutella-like asexual morphs exclusively infecting ants were presented herein, namely, Ophiocordyceps acroasca, Ophiocordyceps bifertilis, Ophiocordyceps subtiliphialida, Ophiocordyceps basiasca, Ophiocordyceps nuozhaduensis and Ophiocordyceps contiispora. …”
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A Performance Evaluation and Inter-laboratory Comparison of Community Face Coverings Media in the Context of COVID-19 Pandemic by Soleiman Bourrous, Mathieu Barrault, Victor Mocho, Stéphane Poirier, Nathalie Bardin-Monnier, Augustin Charvet, Dominique Thomas, Alexandre Bescond, Axel Fouqueau, Tatiana Mace, François Gaie-Levrel, François-Xavier Ouf

“…Abstract During the recent pandemic of SARS-CoV-2, and as a reaction to the worldwide shortage of surgical masks, several countries have introduced new types of masks named “community face coverings” (CoFC). To ensure the quality of such devices and their relevance to slow down the virus spreading, a quick reaction of the certification organisms was necessary to fix the minimal acceptable performances requirements. …”
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A comparison of development methods used to define portion sizes in food-based dietary guidelines around the world by Fanny Salesse, Fanny Salesse, Alison L. Eldridge, Tsz Ning Mak, Eileen R. Gibney, Eileen R. Gibney

“…Analyses across regions revealed that portion recommendations were generally consistent, with significant differences found only for one food group, namely, Fish & shellfish, where portion size recommendations were significantly higher in Europe compared to those in Latin America and the Caribbean.DiscussionResults indicate little variation in the recommendations for portion size across development methods, and for most food groups, across global regions. …”
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A novel framework to predict ADHD symptoms using irritability in adolescents and young adults with and without ADHD by Saeedeh Komijani, Dipak Ghosal, Manpreet K. Singh, Julie B. Schweitzer, Julie B. Schweitzer, Prerona Mukherjee, Prerona Mukherjee

“…Using a non-parametric-based approach, employing the Random Forest (RF) method, we found that among both adolescents and young adults, irritability in adolescent females significantly contributes to predicting impulsive symptoms in subsequent years, achieving a performance rate of 86%.ConclusionOur results corroborate and extend prior findings, allowing for an in-depth examination of longitudinal relations between irritability and ADHD symptoms, namely hyperactivity, impulsivity, and inattentiveness, and the unique association between irritability and ADHD symptoms in females.…”
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Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite by Xi Zhang, Xi Zhang, Yankun Ma, Yankun Ma, Mingye Hu, Aohan Zhao, Aohan Zhao, Wenwang Yang, Wenwang Yang

“…The results show that (1) there are three stages, namely, compression, pore development, and post-peak failure, which promote the development and evolution of medium pore and macropores in lignite. (2) Under uniaxial compression, the permeability of the lignite sample shows a “V-shaped” trend, first decreasing and then increasing. …”
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Causal relationship of familial hypercholesterolemia with risk of intestinal vascular disorders: A mendelian randomization study by Gang Wei, Cheng Zhang, Feng-Jie Shen, Hua-Qi Guo, Lin Liu

“…Rs7575840 in 6.5kda upstream of ApoB gene, rs11591147 in PCSK9 gene and rs9644862 in the CDKN2B-AS1 (or named ANRIL; p15AS; PCAT12; CDKN2BAS; CDKN2B-AS; NCRNA00089) gene were illustrated to mostly influence the risk of intestinal vascular diseases. …”
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Forensic-medical determination of the severity of closed injuries of the hyoid-laryngeal complex according to the data of a specialized clinic by M.V. Gubin, V.O. Olkhovskyi, G.I. Garyuk, V.M. Gubin

“…Injuries of the hyoid-laryngeal complex in 3 (4.8%) patients with the occurrence of life-threatening phenomena, namely acute respiratory failure, were assessed as serious ones. …”
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BenchAMRking: a Galaxy-based platform for illustrating the major issues associated with current antimicrobial resistance (AMR) gene prediction workflows by Nikolaos Strepis, Dennis Dollee, Donny Vrins, Kevin Vanneste, Bert Bogaerts, Catherine Carrillo, Amrita Bharat, Kristy Horan, Norelle L. Sherry, Torsten Seemann, Benjamin P. Howden, Saskia Hiltemann, Leonid Chindelevitch, Andrew P. Stubbs, John P. Hays

“…Further, comparative benchmarking studies are difficult to perform due to differences in AMR gene prediction accuracy and a lack of agreement in the naming of AMR genes (semantic conformity) for the results obtained. …”
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Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China by Haoling Tang, Zhiwei Chen, Tianquan Huang, Pingping Yu, Qiao Tang, Yue Qiu, Yunling Xue, Jing Tang, Nan Cai, Hong Ren, Mingli Peng, Peng Hu

“…The aim of this study is to investigate the clinical characteristics observed during and after Omicron infection among a specific population, namely healthcare workers (HCWs). Methods From November 4, 2022, to January 15, 2023, HCWs in our hospital were enrolled to document clinical symptoms, prevention, and treatment for COVID‐19 using a structured questionnaire. …”
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Equalizer Design: HBOA-DE-trained radial basis function neural networks by Santosh Kumar Das, Satya Ranjan Pattanaik, Pradyumna Kumar Mohapatra, Saroja Kumar Rout, Abdulaziz S. Almazyad, Muhammed Basheer Jasser, Guojiang Xiong, Ali Wagdy Mohamed

“…As an optimization algorithm, a nature-inspired hybrid algorithm is applied, namely BOA/DE, which is a combination of the Butterfly optimization algorithm (BOA) and differential evolution (DE). …”
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Infection of nonclassic monocytes by respiratory syncytial virus induces an imbalance in the CD4+ T-cell subset response by Lianlian Han, Danyang Li, Conghui Wang, Lili Ren, Li Guo, Jianwei Wang

“…To investigate whether RSV affects the imbalance of CD4+ T-cells through monocytes, we examined the effects of the RSV-infected monocyte subset on CD4+ T-cell subsets, namely, Th1, Th2, Th17, and regulatory T (Treg) subsets, on proliferation in vitro and identified key monocyte-derived cytokines. …”
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Pollution Characteristics and Source Analysis of Carbonaceous Components in PM2.5 in a Typical Industrial City by Liyan Ma, Dongmei Hu, Yulong Yan, Yueyuan Niu, Xiaolin Duan, Yafei Guo, Wanhua Li, Lin Peng

“…In this study, online observation data from September 1, 2022, to August 31, 2023, were used to analyze the carbonaceous components, namely, organic carbon (OC) and elemental carbon (EC), in PM2.5 in Jincheng, which is a typical industrial city. …”
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Comparisons of adverse events associated with immune checkpoint inhibitors in the treatment of non-small cell lung cancer: a real-world disproportionality analysis based on the FDA... by Ruichen Gao, Wenjun Liang, Jintao Chen, Mingxia Yang, Xiaowei Yu, Xiaohua Wang

“…Results We analyzed 13,580 reports of AEs associated with five ICIs, namely, durvalumab, pembrolizumab, ipilimumab, atezolizumab, and nivolumab from January 2013 to October 2022. …”
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Isolation and Characterization of Indigenous <i>Acetobacter</i> Strains from Cashew Apple and Their Potential Use in Vinegar Production by Yaya Anianhou Ouattara, Doudjo Soro, Kouakou Romain Fossou, Ahou Cinthia Ines Yebouet, Ismael Abraham Cissé, Dogbo Marius Akissi, Adolphe Zézé, Emmanuel Assidjo, Kouassi Benjamin Yao

“…Phenotypic and phylogenetic analysis revealed that four of them, namely OYA2, OYA6, OYA9, and OYA10, belong to the <i>A. tropicalis</i>/<i>A. senegalensis</i> species complex with 99.7% or 100% similarity. …”
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Students Perceptions, Satisfactions and Challenges on Problem-Based Learning (PBL): A Survey Study Among Final Year Pharmacy Students by Engku Nuraishah Huda E. Zainudin, Fakhira Damia Khaidir, May Khin Soe, Nurul Asyiqin Yusof, Khairool Azizul Mohammad

“…Although, most findings highlight positive aspects of PBL, this study also identified three major challenges in PBL implementation, namely 1) insufficient time for PBL preparation, 2) lack of teamwork, and 3) difficulty in finding adequate reading materials. …”
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