Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study by Daniela Iacono, Serena Fasano, Ilenia Pantano, Virginia D’Abrosca, Piero Ruscitti, Domenico Paolo Emanuele Margiotta, Luca Navarini, Nicola Maruotti, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Antonella Afeltra, Roberto Giacomelli, Gabriele Valentini

“…Patients were subdivided into two groups, namely, ASA- and non-ASA-treated groups. The Kaplan–Meier curve and log-rank test were used to investigate differences in event-free survival. …”
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Angel or devil: the dual roles of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucopyranoside in the development of liver injury based on integrating pharmacological techniques: a system... by Jiajie Jiang, Jiajie Jiang, Qixiu Wang, Qiang Wu, Bobin Deng, Cui Guo, Jie Chen, Jinhao Zeng, Yaoguang Guo, Xiao Ma

“…Background and purpose2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) exhibits a dualistic pharmacological profile, acting as both a hepatoprotective and hepatotoxic agent, which is intricately linked to its interaction with multiple signaling pathways and its stereoisomeric forms, namely, cis-SG and trans-SG. The purpose of this study is to evaluate both the hepatoprotective and hepatotoxic effects of TSG and give therapeutic guidance.MethodsThis study performed a systematic search of eight databases to identify preclinical literature up until March 2024. …”
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Characterization of Essential Oils from Seven <i>Salvia</i> Taxa from Greece with Chemometric Analysis by Spyridon Tziakas, Ekaterina-Michaela Tomou, Panagiota Fraskou, Katerina Goula, Konstantina Dimakopoulou, Helen Skaltsa

“…The present study focused on the characterization of the EOs of seven <i>Salvia</i> taxa growing wild in Greece, namely <i>S. aethiopis</i> L., <i>S. argentea</i> L., and <i>S. sclarea</i> L. …”
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Rooting for Resilience: Arbuscular Mycorrhizal Fungi (AMF) Boost Citrus Tolerance to Water Scarcity in Rangpur Lime and Carrizo Citrange Rootstocks by Sajjad Hussain, Mehwish Jan, Muhammad Fasih Khalid, Sakeena Tul-Ain Haider, Muhammad Arif Ali, Shakeel Ahmad, Samreen Sabir, Mamoudou Sétamou, Raphael Morillon

“…This study aimed to evaluate the response of two different citrus rootstocks—Rangpur lime and Carrizo citrange—when subjected to three mycorrhizal treatments, namely, AMF+ (inoculated with AMF), AMF- (treated with fungicide to eliminate AMF), and a control (naturally occurring AMF), under conditions of water deficit. …”
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Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications by Fernanda Ramírez-Ruiz, Israel Núñez-Tapia, María Cristina Piña-Barba, Marco Antonio Alvarez-Pérez, Vincenzo Guarino, Janeth Serrano-Bello

“…As a function of the used technique, this work aims to offer a comprehensive overview of the benefits/limitations of PCL-based scaffolds in order to establish a relationship between scaffold composition, namely integration of other biomaterial phases’ structural properties (i.e., pore morphology and mechanical properties) and in vivo response.…”
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Maximizing Identification Precision of Hymenoptera and Brachycera (Diptera) With a Non‐Destructive DNA Metabarcoding Approach by Isabel C. Kilian, Ameli Kirse, Ralph S. Peters, Sarah J. Bourlat, Vera G. Fonseca, Wolfgang J. Wägele, Andrée Hamm, Ximo Mengual

“…The study evaluated four distinct approaches, namely clustering to Amplicon Sequence Variants (ASVs) or ASVs clustered to Operational Taxonomic Units (OTUs) coupled with subsequent filtering using the LULU algorithm at 84% and 96% minimum match. …”
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Supramolecular Organic Framework with Multidimensional Storage Spaces for Ultrahigh-Capacity Iodine Capture from Seawater by Lijuan Feng, Jun Zhang, Jiacheng Zhang, Xuewen Cao, Zhanhu Guo, Yihui Yuan, Ning Wang

“…Herein, we developed a 3-dimensional (3D) SOF, named SOF-HTNI, via the self-assembly of 2 adjustable compounds, including the internal amine bond-rotatable 5-(bis(4-carboxybenzyl)amino)isophthalic acid (HT) and the configuration-transformable 4,4′-[1,4-phenylenedi-(1E)-2,1-ethenediyl]bis-pyridine (NI), for highly efficient iodine recovery from seawater. …”
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Machine learning algorithms in constructing prediction models for assisted reproductive technology (ART) related live birth outcomes by Junwei Peng, Xiaoyujie Geng, Yiyue Zhao, Zhijin Hou, Xin Tian, Xinyi Liu, Yuanyuan Xiao, Yang Liu

“…A total of seven predictors were identified, namely maternal age, duration of infertility, basal follicle-stimulating hormone (FSH), progressive sperm motility, progesterone (P) on HCG day, estradiol (E2) on HCG day, and luteinizing hormone (LH) on HCG day. …”
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Economic feasibility, perception of farmers, and environmental sustainability index of sorghum-eucalyptus agroforestry by . Komalawati, S. Hidayat, R.H. Praptana, M.D. Pertiwi, A.S. Romdon, Y. Hidayat, R.P. Ramadhan, D. Yuniati, . Saptana, . Syahyuti, N. Khaririyatun, S. Ika, R.K. Jatuningtyas, . Subiharta, R.N. Hayati, S. Sudarto, M.P. Yufdy, B. Nuryanto, A. Prasetyo

“…This study aimed to analyze the economic feasibility, perception of farmers, and environmental sustainability of sorghum-eucalyptus agroforestry in Majalengka.METHODS: This study innovatively combined qualitative and quantitative methods to assess economic, social, and environmental aspects across five dimensions, namely business organization, actors, working mechanisms, economic impacts, and sustainability of business and environment. …”
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Peculiarities of the blood system of animals under the conditions of consumption of drinking water containing chlorates by T.E. Kravchun, L.A. Tomashevskaya, L.A. Tomashevskaya, V.A. Prokopov, T.V. Kulish, V.S. Tsytsyruk

“…Thus, the nature and features of changes in hematological indicators in the body of experimental animals during a chronic sanitary-toxicological experiment under the influence of chlorates in drinking water may indicate that chlorates affect the indicators of the blood system, being the indirect signs of disorders of other functional systems in the body, namely – slowing of redox reactions, hypoxic manifestations, reduction and weakening of the immune response and reactivity, etc.…”
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Association between body size and atrial myopathy: Investigation using the prevalence of left atrial low-voltage areas by Yasuhiro Matsuda, Masaharu Masuda, Hiroyuki Uematsu, Ayako Sugino, Hirotaka Ooka, Satoshi Kudo, Subaru Fujii, Mitsutoshi Asai, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takuya Tsujimura, Yosuke Hata, Naoko Higashino, Sho Nakao, Masaya Kusuda, Toshiaki Mano

“…BMI was divided into four groups, namely <18.5 kg/m2, 18.5–25.0 kg/m2, 25.0–30.0 kg/m2, ≥30.0 kg/m2. …”
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The Immunohistochemical Prognostic Value of Nuclear and Cytoplasmic Silent Information Regulator 1 Protein Expression in Saudi Patients with Breast Cancer by Bayan Alharbi, Alia Aldahlawi, Mourad Assidi, Fatemah Basingab, Kawther Zaher, Jehan Alrahimi, Sara Mokhtar, Jaudah Al-Maghrabi, Abdelbaset Buhmeida, Kaltoom Al-Sakkaf

“…Background: The mammalian NAD-dependent deacetylase sirtuin-1 family (named also silent information regulator or SIRT family, where NAD stands for “nicotinamide adenine dinucleotide” (NAD)) appears to have a dual role in several human cancers by modulating cell proliferation and death. …”
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Refining and conching alter the volatile composition of dark chocolate — Revealing profile changes in aroma-active volatiles and volatile organic compounds by Yvonne Guckenbiehl, Eva Ortner, Isabell Rothkopf, Andrea Buettner

“…The chocolate volatilome is formed by cocoa variety, growing region, and harvesting season but also by multiple post-harvest processes, namely fermentation, drying, roasting, and conching. …”
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Effects of dietary processed former foodstuffs on slaughter performance and meat quality in broilers by Karthika Srikanthithasan, Marta Gariglio, Elena Diaz Vicuna, Margherita Profiti, Andrea Giorgino, Edoardo Fiorilla, Marta Castrica, Dino Miraglia, Sihem Dabbou, Flavia Gasperi, Ana Cristina Barroeta Lajusticia, Iolanda Altomonte, Rosalba Roccatello, Achille Schiavone, Claudio Forte

“…Two hundred and one-day-old male chicks (ROSS-308) were divided into four dietary groups with increasing levels of cFF (0, 6.25%, 12.5% and 25%) named cFF0, cFF6.25, cFF12.5 and cFF25, respectively. …”
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The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice by Li Li, Jun Li, Hui Xu, Fengmei Zhu, Zhijun Li, Hongzhi Lu, Jinrong Zhang, Zhengsheng Yang, Yongsheng Liu

“…Current study was designed to examine the effect of pretreatment with three anthocyanins named cyanidin-3-arabinoside, cyanidin-3-glucodise, and cyaniding-3-galactoside against acute ischemia-reperfusion injury in mouse kidney. …”
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Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation by Imanuel Lerman, Yifeng Bu, Rahul Singh, Harold A. Silverman, Anuj Bhardwaj, Alex J. Mann, Alik Widge, Joseph Palin, Christopher Puleo, Hubert Lim

“…Knowledge gaps remain and likely contribute to the lack of available closed loop autonomic neuromodulation systems, namely, (1) significant exogenous and endogenous noise that must be filtered out, (2) potential drift in the signal due to temporal change in disease severity and/or therapy induced neuroplasticity, and (3) confounding effects of exogenous therapies (e.g., concurrent medications that dysregulate autonomic nervous system functions). …”
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Comparing International Guidelines for the Remission of Hypertension After Bariatric Surgery by Carina Vieira Dias, Ana Lúcia Silva, Joana Dias, Paulo Cardoso, Rute Castanheira, Andreia Fernandes, Filipa Nunes, Tina Sanai, Mercedes Sanchez, João Maia-Teixeira, Ana Luísa De Sousa-Coelho

“…Dissimilar hypertension guidelines are available for clinicians, namely those prepared by the American Heart Association (AHA) and the European Society of Cardiology (ESC), which may lead to distinctive appreciation of health outcomes of patients with obesity after bariatric and metabolic surgery, such as hypertension remission. …”
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Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach by Genbao Zhu, Genbao Zhu, Genbao Zhu, Zhiming Jiang, Niuping Zhu, Niuping Zhu, Donghui Wang, Donghui Wang, Tianpeng Guo, Tianpeng Guo, Yiqing Meng, Yiqing Meng, Yi Zhu, Yi Zhu, Kemeng Tan, Mengxue Hu, Heng Tang, Xuannian Wang, Xuannian Wang

“…Lastly, in vitro experiments were performed for validation.ResultsA least of four key targets, namely BCL2 apoptosis regulator (BCL2), estrogen receptor 1 (ESR1), hypoxia-inducible factor 1 subunit alpha (HIF1A), and signal transducer and activator of transcription 3 (STAT3) were identified in this study, and molecular docking analyses revealed that SSA stably binds to these targets. …”
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Mechanism of Threshold Voltage Instability in Double Gate &#x03B1;-IGZO Nanosheet TFT Under Bias and Temperature Stress by Muhammad Aslam, Shu-Wei Chang, Yi-Ho Chen, Yao-Jen Lee, Yiming Li, Wen-Hsi Lee

“…Given the demand for CMOS-compatible, ultra-scaled, reliable, and high-performing devices, we fabricate and analyze scaled-channel a-IGZO-TFTs with an optimal double-gate structure, a thin nanosheet-based channel, and an effective high- <inline-formula> <tex-math notation="LaTeX">$\kappa$ </tex-math></inline-formula> dielectric namely HfO2. The reliably reported double gate IGZO nanosheet TFTs (DG-IGZO-NS-TFTs) are tested under positive and negative bias stress at variant temperatures, and the resulting modulations are analyzed critically. …”
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PortNet: Achieving lightweight architecture and high accuracy in lung cancer cell classification by Kaikai Zhao, Youjiao Si, Liangchao Sun, Xiangjiao Meng

“…Method: This paper introduces a model named PortNet, designed to significantly reduce the model's parameter size and achieve lightweight characteristics without compromising classification accuracy. …”
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