Reply to: Comments on “a comparative study of sexual behavior, dysfunction, satisfaction, relationship, and sexual quality of life amongst treatment naïve and abstinent men (buprenorphine-maintained) with opioid (heroin) dependence syndrome” by Mahadev Singh Sen, Ankita Chattopadhyay, Nishtha Chawla, Ragul Ganesh, Suraj Verma, Siddharth Sarkar, Atul Ambekar

Get full text

Dosing intervals in Comparison of one-year real-world outcomes between red (670 nm) subthreshold micropulse laser treatment and intravitreal aflibercept injection for treatment-naïve diabetic macular edema by Kai Ching Peter Leung, Sunny, Chi Lik Au

Get full text

Anomaly Detection in Network Traffic Using Advanced Machine Learning Techniques by Stephanie Ness, Vishwanath Eswarakrishnan, Harish Sridharan, Varun Shinde, Naga Venkata Prasad Janapareddy, Vineet Dhanawat

Subjects: Get full text

Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naïve Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-Month, Single-Arm, Multicentre Trial by Jose Garcia-Arumi, Francisco Gómez-Ulla, Navea Amparo, Enrique Cervera, Alex Fonollosa, Luis Arias, Javier Araiz, Juan Donate, Marta Suárez de Figueroa, Lucia Manzanas, Jaume Crespí, Roberto Gallego

“…Phase IV, prospective, open-label, single-arm trial in 11 Spanish hospitals. Treatment-naïve patients with <6 month diagnosis of MO secondary to CRVO and best-corrected visual acuity (BCVA) of 73-24 ETDRS letters were included between 23 January 2015 and 17 March 2016. …”
Get full text

Liver Enzymes Abnormalities among Highly Active Antiretroviral Therapy Experienced and HAART Naïve HIV-1 Infected Patients at Debre Tabor Hospital, North West Ethiopia: A Comparative Cross-Sectional Study by Melashu Balew Shiferaw, Ketema Tafess Tulu, Amtatachew Moges Zegeye, Amarech Asratie Wubante

“…Hence, liver enzyme abnormalities among highly active antiretroviral therapy (HAART) experienced and HAART naïve patients were assessed in this study. A total of 164 HAART experienced and 164 HAART naïve patients were studied. …”
Get full text

Transformer les conceptions naïves à l'aide de clips vidéo. Analyser puis scénariser une vidéo aide les futurs ingénieurs à intégrer le système de pensée newtonien by Benoît Raucent, Christian Ritter, Jim Plumat, Pascale Corten-Gualtieri

“…This paper presents an experiment in collaborative learning with small teams aiming at helping students to relinquish their naïve intuitions about dynamics. An important aspect of this experiment is that students were asked to both critically analyze the contents of video clips illustrating mechanical dynamics and design and realize their own video clip. …”
Get full text

Body mass index, proteinuria and total lymphocyte counts in predicting treatment responses among ART naïve individuals with HIV initiated on antiretroviral treatment in Dar es Salaam, Tanzania, 2019: a cohort study by Ellen Hertzmark, Patricia Munseri, Lazaro Jassely, Basil Tumaini

Get full text

Application of machine learning in the fake user identification of IoT by Rongfang ZHANG, Dandan XU, Yuanguang WANG, Siyu PAN, Zhengmao LI

Subjects: Get full text

Machine Learning with Tunicate Swarm Optimization for Improved Disc Herniation Prediction by Theofilos Gofas, Argyros Maris

Subjects: Get full text

HANDLING OF STUDENT FEEDBACK BASED ON TEXT CLASSIFICATION by Phạm Thị Kim Ngoan, Nguyễn Hải Triều

Subjects: “…naive bayesian classification (nbc)…”
Get full text

Exploring SLEEPINESS through home monitoring with ultra-long-term subcutaneous EEG and ecological momentary assessment in sleepy treatment naïve obstructive sleep apnea patients starting CPAP treatment—A study protocol article by Mathias Sarkez-Knudsen, Martin Ballegaard, Martin Ballegaard, Henning Piilgaard, Esben Ahrens, Martin Christian Hemmsen, Tobias Søren Andersen, Jakob Eyvind Bradram, Preben Homøe, Preben Homøe

“…We hypothesize that the high-frequency testing from ULT-EEG, in combination with an ecological momentary assessment (EMA), can provide the information to develop new electrophysiological monitoring of sleep propensity as an alternative to the well-established, yet subjective, ESS.MethodsThis clinical exploratory and experimental study will include 15 treatment-naïve patients with severe OSA, with a baseline ESS score above 10. …”
Get full text

Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-label, phase II, randomised controlled trial by Ying Zhu, Jianwei Zhou, Zhigang Zhang, Jiaojiao Zhang, Jing Fei, Xiaoqing Zhu

“…The NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr(NAIVE) study aims to assess the clinical efficacy and safety of NACT in combination with tislelizumab (a monoclonal antibody for programmed cell death protein 1) for advanced EOC.Methods and analysis The NAIVE study is an investigator-initiated, prospective, single-centre, open-label, randomised controlled trial for advanced EOC with the International Federation of Gynaecology and Obstetrics (FIGO) stage IIIc with a Suidan CT score of 3 or greater or a Fagotti laparoscopic score of 8 or greater; or FIGO stage IV. …”
Get full text

IoT-Based Multisensors Fusion for Activity Recognition via Key Features and Hybrid Transfer Learning by Ahmad Jalal, Danyal Khan, Touseef Sadiq, Moneerah Alotaibi, Sultan Refa Alotaibi, Hanan Aljuaid, Hameedur Rahman

Subjects: Get full text

Efficacy and safety of surufatinib plus toripalimab in treatment-naive, PD-L1-positive, advanced or metastatic non-small-cell lung cancer and previously treated small-cell lung cancer: an open-label, single-arm, multicenter, multi-cohort phase II trial by Ying Cheng, Panpan Zhang, Ming Lu, Zhendong Chen, Lijie Song, Si Shi, Feng Ye, Xing Zhang, Baorui Liu, Dongmei Ji, Yanqiao Zhang, Weiguo Su, Michael Shi, Songhua Fan, Panfeng Tan, Chen Zhong

“…Methods This open-label, single-arm phase II study included patients with treatment-naive advanced or metastatic PD-L1-positive NSCLC or previously treated SCLC in China. …”
Get full text

TROPION-Breast04: a randomized phase III study of neoadjuvant datopotamab deruxtecan (Dato-DXd) plus durvalumab followed by adjuvant durvalumab versus standard of care in patients with treatment-naïve early-stage triple negative or HR-low/HER2− breast cancer by Heather L. McArthur, Sara M. Tolaney, Rebecca Dent, Peter Schmid, Jamil Asselah, Qiang Liu, Jane Lowe Meisel, Naoki Niikura, Yeon Hee Park, Gustavo Werutsky, Giampaolo Bianchini, Jay C. Andersen, Robert Kozarski, Nana Rokutanda, Barbara Pistilli, Sibylle Loibl

Get full text

Profitability Analysis of Price-Taking Strategy in Disequilibrium by Weihong Huang

“…Conventional economic assumption that more sophistication in decision making is better than less is challenged with a profitability analysis conducted with an oligopolistic model consisting of a naive firm and a group of sophisticated firms. While the naive firm is assumed to adopt a simple Cobweb strategy by equating its marginal cost of current production to the last period's price, the sophisticated firms can take either individually or collusively any conventional sophisticated strategy such as Cournot and Stackelberg strategies. …”
Get full text

Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model... by HyeJu Jeong, Ok Joon Kim, Seung-Hun Oh, Sanghoon Lee, Han A. Reum Lee, Kee Ook Lee, Boo-Yong Lee, Nam Keun Kim

“…Extracellular vesicles (EVs) were equally observed in the hippocampus in the naïve and NEP-enhanced hUC-MSC groups. However, the EVs of NEP-enhanced hUC-MSCs contained higher amounts of NEP as compared to the EVs of naïve hUC-MSCs. …”
Get full text

Switch of Intravitreal Therapy for Macular Edema Secondary to Retinal Vein Occlusion from Anti-VEGF to Dexamethasone Implant and Vice Versa by Amelie Pielen, Anima Desiree Bühler, Sonja Ute Heinzelmann, Daniel Böhringer, Thomas Ness, Bernd Junker

“…Functional gain was limited compared to treatment naïve eyes, probably due to worse BCVA and CFT at baseline in treatment naïve eyes.…”
Get full text

Comparison of bison and elk susceptibility to experimental challenge with Brucella abortus strain 2308 by S. C. Olsen, P. M. Boggiatto, E. J. Putz

“…Vaccinated bison had lower (p &lt; 0.002) abortion rates and recovery of Brucella from fetal or uterine/mammary tissues when compared to naïve bison. Vaccinated elk had reduced (p &lt; 0.01) rates of maternal infection, but rates of abortion and fetal or uterine/mammary infection did not differ (p &gt; 0.05) from naïve elk. …”
Get full text

Microbiota alterations in patients treated for susceptible or drug-resistant TB by M. Hauptmann, B. Kalsdorf, J.E. Akoh-Arrey, C. Lange, U.E. Schaible

“…RESULTS: From September 2018 to December 2019, 5 participants with treatment-naïve TB, 6 participants with DS-TB, 10 participants with DR-TB-inj–, and 4 participants with DR-TB-inj+ were recruited. …”
Get full text