scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria by Collins M. Morang’a, Riley S. Drake, Riley S. Drake, Riley S. Drake, Riley S. Drake, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Nancy K. Nyakoe, Dominic S. Y. Amuzu, Vincent Appiah, Yaw Aniweh, Yaw Bediako, Saikou Y. Bah, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Gordon A. Awandare, Thomas D. Otto, Lucas Amenga-Etego

“…Further, in the patients, we identified more putative interactions between antigen-presenting cells and proliferating CD4 T cells, and naïve CD8 T cells driven by MHC-I and MHC-II signaling pathways, respectively. …”
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Phase I study of intratumoral administration of CV8102 in patients with advanced melanoma, squamous cell carcinoma of the skin, squamous cell carcinoma of the head and neck, or ade... by Lucie Heinzerling, Michael Fluck, Caroline Robert, Celeste Lebbe, Erika Richtig, Sven D Koch, Ulrike Gnad-Vogt, Tobias Seibel, Thomas Eigentler, Juan Martin-Liberal, Sebastian Ochsenreither, Peter Mohr, Patrick Terheyden, Carsten Weishaupt, Michael Erdmann, Lukas Koch, Ainara Soria, Igor Samoylenko, Jürgen Krauß, Peter Brossart, Franz Georg Bauernfeind, Marina Gonzalez, Peter Wengenmayer, Ioannis Thomas, Artem Poltoratskiy, Marina Sekacheva, Beate Schmitt-Bormann, Gianluca Quintini, Martin Falk, Paula Codó, Arjun Oberoi, Jana Hess, Yulia Semiletova, Casilda Llacer Perez, Oliver Schönborn-Kellenberger

“…We investigated intratumoral (IT) administration of CV8102 in patients with anti-programmed cell death protein-1 (PD-1) therapy-naïve or anti-PD-1 therapy-refractory cutaneous melanoma (cMEL) and in patients with advanced cutaneous squamous cell carcinoma, head and neck squamous cell carcinoma and adenoid cystic carcinoma.Methods This open-label, cohort-based, phase I dose escalation study aimed to establish the maximum tolerated dose (MTD), recommended dose (RD), safety and preliminary efficacy of CV8102 as monotherapy or in combination with a PD-1 inhibitor. …”
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Development, validation, and clinical application of a machine learning model for risk stratification and management of cervical cancer screening based on full-genotyping hrHPV tes... by Binhua Dong, Zhen Lu, Tianjie Yang, Junfeng Wang, Yan Zhang, Xunyuan Tuo, Juntao Wang, Shaomei Lin, Hongning Cai, Huan Cheng, Xiaoli Cao, Xinxin Huang, Zheng Zheng, Chong Miao, Yue Wang, Huifeng Xue, Shuxia Xu, Xianhua Liu, Huachun Zou, Pengming Sun

“…Methods: We developed, compared and validated four machine learning models (eXtreme gradient boosting [XGBoost], support vector machine [SVM], random forest [RF], and naïve bayes [NB]) for cervical cancer prediction, using data from a national cervical cancer screening project conducted in 267 healthcare centers in China. …”
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The Bioethics-CSR Divide by Caio Caesar Dib

“…Proper training enables the bioethicist to avoid falling into traps of subjectivism or moralism, which are unable to address the complexity of decision-making. It also prevents the naïve seduction of “scientifying” ethics.[33] This is the starting point of a multitude of roles that can be attributed to the bioethicists. …”
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Análise crítica dos processos de intervenção psicossocial em comunidades e favelas by Nadir Lara Junior, Cynara Teixeira Ribeiro

“…The aim is to critically analyze the professionals acting in communities and favelas and how they accept certain concepts naively, maintaining logic of domination in capitalist society. …”
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Call and Response by Jesse Foster Honsa

“… A "housing crisis" is often naively understood as a simple market imbalance between supply and demand, frequently occurring within cities in a capitalist mode of development. …”
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Les voix post-humaines : Le thème de l’infestation extra-terrestre et la poétique de la subjectivité by Elana Gomel

“…Je suggère également que, plutôt que d’être catégorisées comme de naïves allégories politiques, ces œuvres doivent être lues en termes de tensions discursive et idéologique au sein de l’humanisme.…”
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Compact scheme with two-sided estimates for nonlinear convection-diffusion-reaction equations by Chinedu Nwaigwe

“…This is challenging, especially due to the convection term which can easily lead to oscillatory solutions if naively approximated. This paper proposes a spatially second-order scheme which is able to simulate purely-convection problems with high-order accuracy on minimal stencil. …”
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Subset-Selection Weight Post-Training Quantization Method for Learned Image Compression Task by Jinru Yang, Xiaoqin Wang, Qiang Li, Shushan Qiao, Yumei Zhou

“…Post-training quantization(PTQ) has been widely studied in recent years because it does not require retraining the network or the entire training dataset. However, naively applying the PTQ method to quantize low-level image tasks such as learned image compression(LIC) usually incurs significant accuracy degradation. …”
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DM-KD: Decoupling Mixed-Images for Efficient Knowledge Distillation by Jongkyung Im, Younho Jang, Junpyo Lim, Taegoo Kang, Chaoning Zhang, Sung-Ho Bae

“…However, we discover that naively applying mixed-augmentation to KD impacts the student model’s learning through knowledge distillation negatively. …”
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Efficient calculation of self magnetic field, self-force, and self-inductance for electromagnetic coils with rectangular cross-section by Matt Landreman, Siena Hurwitz, Thomas M. Antonsen

“…For these force, inductance, energy, and internal field calculations, the coils cannot be naively approximated as infinitesimally thin filaments due to divergences when the source and evaluation points coincide, so more computationally demanding calculations are usually required, resolving the finite cross-section of the conductors. …”
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Prompt Conditioned Batik Pattern Generation Using LoRA Weighted Diffusion Model With Classifier-Free Guidance by Rahmatulloh Daffa Izzuddin Wahid, Novanto Yudistira, Candra Dewi, Irawati Nurmala Sari, Dyanningrum Pradhikta, Fatmawati

“…A pretrained LDM was subsequently fine-tuned on its denoising U-Net part, either by naively fine-tuned the entire layer or by employing using LoRA. …”
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