Grazoprevir and Elbasvir in Patients with Genotype 1 Hepatitis C Virus Infection: A Comprehensive Efficacy and Safety Analysis by Yinan Yao, Ming Yue, Jie Wang, Hongbo Chen, Mei Liu, Feng Zang, Jun Li, Yun Zhang, Peng Huang, Rongbin Yu

“…Results. 568 (73%) patients were treatment-naive. Overall, 95% (95% CI: 93–96) patients achieved SVR12, 95% (95% CI: 92–96) for treatment-naive and 96% (95% CI: 92–98) for previously treated patients, respectively. …”
Get full text

Trichostatin A Promotes the Generation and Suppressive Functions of Regulatory T Cells by Cristian Doñas, Macarena Fritz, Valeria Manríquez, Gabriela Tejón, María Rosa Bono, Alejandra Loyola, Mario Rosemblatt

“…Here we show that the foxp3 gene promoter becomes hyperacetylated in in vitro differentiated Tregs compared to naïve CD4+ T cells. We also show that the histone deacetylase inhibitor TSA stimulated the in vitro differentiation of naïve CD4+ T cells into Tregs and that this induction was accompanied by a global increase in histone H3 acetylation. …”
Get full text

Preprocessing Data dan Klasifikasi untuk Prediksi Kinerja Akademik Siswa by Takhamo Gori, Andi Sunyoto, Hanif Al Fatta

“…Sebelum CFS, model Naïve Bayes menunjukkan accuracy sebesar 89.27%, dengan recall, precision, danf1-score masing-masing sebesar 89.27%, 89.86%, dan 89.47%. …”
Get full text

Secukinumab Treatment in Patients With Hidradenitis Suppurativa in Real-World Clinical Settings: A Multicenter Study by Ece Erbağcı, Özge Sevil Karstarlı Bakay, Fatma Aslı Hapa

“…Nine (29%) patients were biologic-naive and 10 (32.3%) were adalimumab-naive. Disease severity was Hurley I in 7 patients (22.6%), Hurley II in 9 patients (29%), and Hurley III in 15 patients (48.4%). …”
Get full text

Machine learning-assisted cancer diagnosis in patients with paraneoplastic autoantibodies by Alireza Maleki, Mohammad Mahdi Mirza Ali Mohammadi, Shahab Gholizadeh, Behnaz Dalvandi, Mohammad Rahimi, Aidin Tarokhian

“…The study included participants who tested positive for at least one autoantibody. Naive Bayes model was used to predict cancer presence. …”
Get full text

Use of Anabolic-Androgenic Steroids and Male Fertility: A Systematic Review and Meta-analysis by Prashant Motiram Mulawkar, Pankaj N. Maheshwari, Vineet Gauhar, Sumeet Gopal Agrawal, Taofiq Olayinka Mohammed, Abhishek Gajendra Singh, Gopal Ramdas Tak, Utsav Shailesh Shah, Deepali Parthsarthi Shukla, Deepali Mamankar

“…One year after stopping AAS, the users and naïve population had insignificant differences in FSH and LH values. …”
Get full text

Treatment of neovascular age-related macular degeneration: one year real-life results with intravitreal Brolucizumab by Settimio Rossi, Carlo Gesualdo, Ernesto Marano, Raffaele Perrotta, Maria Consiglia Trotta, Antonio Del Giudice, Francesca Simonelli

“…We identified two groups: group 1 (24 treatment-naïve eyes) that received a loading dose of 3 monthly intravitreal injections of Broluciziumab 6 mg (0.05 mL solution) + Q8w/Q12w regimen, and a Group 2 (20 non-naïve eyes) which performed 1 injection + ProReNata (PRN) scheme. …”
Get full text

Real-world satisfaction and experience with injection and autoinjector device for ofatumumab indicated for multiple sclerosis by Amy Perrin Ross, Jacqueline Nicholas, Ming-Hui Tai, Stephen Yeung, Nazneen Fatima Shaikh, Helen Chen, Mariana Fernandes, Aaron Cortright, Kevin Hawkins

“…The overall mean (SD) satisfaction score with Sensoready device was 4.4 (0.7), with a higher device satisfaction reported in the DMT-experienced vs. DMT-naïve group (4.6 [0.66] vs. 4.1 [0.69]). A higher proportion of DMT-experienced patients reported high satisfaction scores as compared to DMT-naïve patients (90.8% vs. 80.0%). …”
Get full text

PREDICTION OF TELECOM SERVICES CONSUMERS CHURN BY USING MACHINE LEARNING ALGORITHMS by Edin Osmanbegović, Anel Džinić, Mirza Suljić

“…Some of the most commonly used machine learning algorithms for this issue are Logistic Regression, Gaussian Naive Bayes, Bernoulli Naive Bayes, Decision Tree, and Random Forest. …”
Get full text

PREDICTION OF TELECOM SERVICES CONSUMERS CHURN BY USING MACHINE LEARNING ALGORITHMS by Edin Osmanbegović, Anel Džinić, Mirza Suljić

“…Some of the most commonly used machine learning algorithms for this issue are Logistic Regression, Gaussian Naive Bayes, Bernoulli Naive Bayes, Decision Tree, and Random Forest. …”
Get full text

Optical Coherence Tomography Angiography to Distinguish Changes of Choroidal Neovascularization after Anti-VEGF Therapy: Monthly Loading Dose versus Pro Re Nata Regimen by Alexandra Miere, Hassiba Oubraham, Francesca Amoroso, Pauline Butori, Polina Astroz, Oudy Semoun, Elsa Bruyere, Alexandre Pedinielli, Manar Addou-Regnard, Camille Jung, Salomon Y. Cohen, Eric H. Souied

“…Conclusion. Treatment-naïve and treated eyes with CNV secondary to neovascular AMD respond differently to anti-VEGF therapy. …”
Get full text

Commensal bacteria education history calibrates the naivety and activation threshold of adaptive antiviral immune system by Baohua Li, Zhou Sha, Li Mou, Feng Zhang, Lifeng Jia, Yan Zhu, Yan Guo, Guohong Deng, Haibo Wu, Hong Wei, Yuzhang Wu, Lilin Ye, Changjiang Liu, Jian Li, Yanyan Zhang, Yanyan Zhang, Yanyan Zhang

“…Interestingly, the naive GF immune system showed robust T-cell responses, with more potent memory T cells established for long-term protection, even in the condition of primary lower T-cell levels for naive GF mice. …”
Get full text

Patient Preference for Once-Weekly Dosing in Type 2 Diabetes Mellitus in Japan by Rohini Sen, Alan L. Shields, Koichiro Atsuda

“…Daily dosing was preferred over QW dosing in the overall population, however, preference for QW was higher in younger, full-time working, treatment naïve subjects, who are/or currently taking 0 or 1 drugs or more than 6 drugs.…”
Get full text

Value of Systematic and MRI‐Ultrasound Fusion Prostate Biopsy in Different Prostate Specific Antigen (PSA) Levels by Solmaz Ohadian Moghadam, Mohammad Haddadi, Erfan Amini, Seyed Ali Momeni, Masoud Bitaraf, Mohammad Reza Nowroozi

“…This study aims to determine the optimal approach in biopsy‐naïve men, according to their PSA levels. Methods and Results A retrospective chart review of clinically suspicious biopsy‐naïve men who underwent both TRUS‐Bx and MRI‐TBx was done. …”
Get full text

Statistical Analysis of Public Sentiment on the Ghanaian Government: A Machine Learning Approach by John Andoh, Louis Asiedu, Anani Lotsi, Charlotte Chapman-Wardy

“…This study statistically assessed the performance of Naive Bayes, support vector machine (SVM), and random forest algorithms on sentiment text classification task. …”
Get full text

Economic Evaluation of Boceprevir for the Treatment of Patients with Genotype 1 Chronic Hepatitis C Virus Infection in Hungary by Raymond Odhiambo, Jagpreet Chhatwal, Shannon Allen Ferrante, Antoine El Khoury, Elamin Elbasha

“…The objective of this study was to evaluate the cost-effectiveness of triple therapy in both treatment-naive and treatment-experienced patients in Hungary. …”
Get full text

Dark Side of the Career: Reflections from an Online Discussion Platform by Zeynep Görgülü, Hasan Bozgeyikli

“…In naïve cluster, users expressed how different their expectations in working life from reality. …”
Get full text

Sztuki plastyczne w naiwnych teoriach uczniów edukacji wczesnoszkolnej by Dorota Sobierańska, Aleksandra Szyller

“…From the earliest years, thanks to the interpretation of the observed events and on the basis of social and cultural messages, children have been independently building naive theories of the world referring to concepts from the visual arts fi eld. …”
Get full text

The Effects of Affinity Mediated Clonal Expansion of Premigrant Thymocytes on the Periphery T-Cell Repertoire by Guanyu Wang

“…The model was basedon the assumption that the clone size is uniformly distributed inthe naive T-cell repertoire. However, recent biological findingshave indicated that the naive T-cell repertoire is highly skewed,due to the uneven proliferation of premigrant single-positivethymocytes. …”
Get full text

Spinal neuromodulation using ultra low frequency waveform inhibits sensory signaling to the thalamus and preferentially reduces aberrant firing of thalamic neurons in a model of ne... by Martyn G. Jones, Martyn G. Jones, Liam A. Matthews, Liam A. Matthews, Scott Lempka, Scott Lempka, Scott Lempka, Nishant Verma, James P. Harris, Stephen B. McMahon

“…On-going activity unrelated to hindlimb stimulation, observed in 17 of 39 neurons in naïve animals (44%), was reduced by lumbar epidural ULF current in only 3 of 14 (21%) neurons tested with ULF. …”
Get full text