Cardiac Dedifferentiated Liposarcoma Requiring a Mitral Valve Replacement Complicated by Severe Paravalvular Leak: A Rare Case Report with Literature Review by Anju Adhikari, Adam Hafeez, Alexandra Halalau

“…However, when symptomatic, their presentation can differ based on the localized structural effects on the endocardium, myocardium, pericardium, and valves as well as on dynamic effects on the cardiac function. …”
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Chronic coronary occlusions in patients after coronary artery bypass grafting. Morphological features and a review of possible interventions by S.М. Furkalo

“…In view of the difficulty of access, spastic reactions, small diameter of the artery and a large area of myocardium that feeds IMA, use of the IMA for the chronic total occlusion (CTO) recanalization is limited. …”
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PET-CT Imaging in Hypertrophic Cardiomyopathy: A Narrative Review on Risk Stratification and Prognosis by Patrícia Marques-Alves, Lino Gonçalves, Maria João Ferreira

“…Positron emission tomography (PET), through the evaluation of myocardial blood flow (MBF) and metabolism using fluorodeoxyglucose (FDG) uptake, can reveal microvascular dysfunction, ischemia, and increased metabolic demands in the hypertrophied myocardium. These abnormalities are linked to several factors influencing disease progression, including arrhythmia development, ventricular dilation, and myocardial fibrosis. …”
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Rare Case of Rapidly Worsening REM Sleep Induced Bradycardia by Ayyappa S. Duba, Suneetha Jasty, Ankit Mahajan, Vijay Kodadhala, Raza Khan, Prithviraj Rai, Mohammad Ghazvini

“…Sinoatrial arrest also known as sinus pause occurs when sinoatrial node of the heart transiently ceases to generate the electrical impulse necessary for the myocardium to contract. It may last from 2.0 seconds to several minutes. …”
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Immunological Regulation of Fibrosis During Heart Failure: It Takes Two to Tango by Vinay Kumar, Shyam S. Bansal

“…Incomplete resolution coupled with sustained low-grade inflammation during dilated cardiomyopathy precipitates a “frustrated” immune cell response resulting in unconstrained pro-fibrotic and pro-hypertrophic signaling to induce maladaptive structural and functional changes in the myocardium. The aims of this review are to (i) briefly summarize the role of key immune cells that regulate wound healing during MI and fibrosis during LV remodeling; (ii) underscore phenotypic diversities in immune cells and their subsets to underscore their role in regulating fibrotic responses, and, last but not the least, (iii) highlight gaps in our understanding that restrict the translation of immuno-modulatory therapies from the preclinical models to heart failure patients.…”
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Hyaluronan and Collagen in Human Hypertrophic Cardiomyopathy: A Morphological Analysis by Martin Hellström, Anna Engström-Laurent, Stellan Mörner, Bengt Johansson

“…CD44 was not detected in the myocardium of patients or controls. Collagen I showed the same general localisation as HA but detailed distribution differed. …”
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Cardiovascular rehabilitation. Results in the cardiology service. by Juan José Navarro López, Roberto S. Vega Hernández., Claudio González Rodríguez., Teresa Rodríguez Rodríguez

“…<strong><br />Results </strong>: Out of the total of patient, 25 are males (83.3%), the diagnoses were: myocardium sharp attack, arterial hypertension with angina, myocardial revascularization and stable angina. …”
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Persistent Hiccups as the Only Presenting Symptom of ST Elevation Myocardial Infarction by Nasreen Shaikh, Rishi Raj, Srinivas Movva, Charles Mattina

“…He underwent diagnostic catheterization which demonstrated 100% right coronary artery occlusion and a thallium viability study which confirmed nonviable myocardium; hence, he did not undergo percutaneous coronary intervention. …”
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Stem Cells for Cardiac Repair: Status, Mechanisms, and New Strategies by Ren Mingliang, Zhang Bo, Wang Zhengguo

“…It is expected to replace and repair damaged myocardium. But many clinical trials have shown that the stem cell therapy of heart failure is modest or not effective. …”
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Fabrication of a Lead Head Made of the Carbon-Fiber-Reinforced Composite for the Temporary Cardiac Pacemaker by Yucheng Zhou, Xuming Lin, Zhao Yang, Xiaotong Han, Meng Liu

“…The results showed that the resistivity of the whole lead did not change significantly after modification, and the carbon fiber bundle was stable and easily deformed under lower stress to reduce the damage to the myocardium, which had excellent clinical application value.…”
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An Unusual Presentation of a Myocardial Crypt in Hypertrophic Cardiomyopathy by Danny A. J. P. van de Sande, Jan Hoogsteen, Luc J. H. J. Theunissen

“…CMR confirmed the diagnosis of HCM in the anteroseptal myocardium with a thickness of 23 mm and also revealed large and deep myocardial crypts in the anterior wall. …”
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Acute Ventricular Wall Thickening: Sepsis, Thrombotic Microangiopathy, or Myocarditis? by Nicolas De Schryver, Delphine Hoton, Diego Castanares-Zapatero, Philippe Hantson

“…Echocardiography revealed an impressive diffuse thickening of the whole myocardium (interventricular septum 18 mm; posterior wall 16 mm) with diffuse hypokinesia and markedly reduced left ventricular ejection fraction (31%). …”
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T2-Weighted Cardiac Magnetic Resonance Imaging of Edema in Myocardial Diseases by Yasuo Amano, Masaki Tachi, Hitomi Tani, Kyoichi Mizuno, Yasuhiro Kobayashi, Shinichiro Kumita

“…T2-weighted MRI of edema identifies myocardial edema associated with ischemia, inflammation, vasculitis, or intervention in the myocardium and provides information complementary to delayed-enhancement MRI.…”
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miRNAs in Extracellular Vesicles from iPS-Derived Cardiac Progenitor Cells Effectively Reduce Fibrosis and Promote Angiogenesis in Infarcted Heart by Wanling Xuan, Lei Wang, Meifeng Xu, Neal L. Weintraub, Muhammad Ashraf

“…Amongst the highly enriched miRNAs, miR-373 was strongly antifibrotic, targeting 2 key fibrogenic genes, GDF-11 and ROCK-2. miR-373 mimic itself was highly efficacious in preventing scar formation in the infarcted myocardium. Together, these novel findings have important implications with regard to prevention of postinfarction remodeling.…”
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Treinta y seis horas de cambios eléctricos en la miocarditis fulminante by Ignacio Morales-Rey, Sara Vázquez, Brayan Rubio, Elena Sandoval, Daniel Pereda

“…Despite adequate medical therapy and mechanical circulatory support, the myocardium never recovered, and she needed an urgent heart transplant.…”
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Protective Role of Platelets in Myocardial Infarction and Ischemia/Reperfusion Injury by Kornela Hałucha, Alina Rak-Pasikowska, Iwona Bil-Lula

“…The standard therapy for ischemia is revascularization and restoration of blood flow to previously ischemic myocardium. Paradoxically, reperfusion may result in further tissue damage called ischemia/reperfusion injury (IRI). …”
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Microtissues in Cardiovascular Medicine: Regenerative Potential Based on a 3D Microenvironment by Julia Günter, Petra Wolint, Annina Bopp, Julia Steiger, Elena Cambria, Simon P. Hoerstrup, Maximilian Y. Emmert

“…However, current stem cell therapies using single-cell suspensions have failed to demonstrate long-lasting efficacy due to the overall low retention rate after cell delivery to the myocardium. To overcome this obstacle, the concept of 3D cell culture techniques has been proposed to enhance therapeutic efficacy and cell engraftment based on the simulation of an in vivo-like microenvironment. …”
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Inhibition of TNF-α and JNK Signaling Pathway Can Reduce Paclitaxel-Induced Apoptosis of Mouse Cardiomyocytes by Shuang Ren, Tianwen Huang, Danyan Ou, Luhuai Feng, Sisi Huang, Chaonan Zhou, Lianying Ge

“…In this study, we initially injected PTX into mice to establish a myocardial cell apoptosis model to observe the degree of damage to mouse myocardium caused by PTX. Upon determining the levels of mouse myocardial creatine phosphokinase (CK), myokinase isoenzyme (CK-MB), aspartate transaminase (AST), and lactate dehydrogenase (LDH), we found that all of these levels showed apparent increases in mice treated with PTX. …”
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Atrioventricular heart valves of indigenous cattle (bos indicus): the morphology and morphometry by Md. Nazrul Islam, Ferdaus Mohd. Altaf Hossain, Shahena Akhtar, Masud Alam

“…The tricuspid and bicuspid valves were harvested by opening the four chambers of the collected heart specimen by placing finger tightly into the cusps of the valves and then the ventricular myocardium muscle trimmed out by scissor slowly. Harvested valves were gently packed with cotton wool to maintain the normal architecture of the leaflets and then preserved in 10% formalin solution.…”
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Changes and Relationship of PAF and TNF in Rats with Myocardial Ischaemia and Reperfusion Injury by Ya-Ling Han, Shao-Ha Li, Qin-Yue Zheng, Hong-Bin Wang, Guo-Yan Zhang, Zhong-Gui Wu, Si-Cong Chen

“…The present results indicate that PAF and TNF may be important mediators involved in myocardial ischaemia and reperfusion injury, and that PAF antagonists may exert a protective effect on ischaemic or reperfused myocardium by inhibiting the interaction of PAF and TNF.…”
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