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1541
Anti-Interleukin-22-Neutralizing Antibody Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Mice
Published 2017-01-01“…In addition, angiotensin II-treated mice received an injection of anti-IL-22-neutralizing antibody (nAb) to investigate the effects of IL-22 nAb on myocardial hypertrophy, cardiac function, and cardiac fibrosis; the activation of the signaling pathway and the prohypertrophic inflammatory cytokine mRNA levels was detected. …”
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1542
A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction
Published 2025-02-01“…On flow cytometry, myocarditis was associated with an increase of most myocardial immune cell populations, including multiple T cell and macrophage subsets, corroborating the notion that T. brucei-associated cardiac damage is an immune-mediated event. …”
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1543
Clinical Implications of Bifurcation Angles in Left Main Bifurcation Intervention Using a Two-Stent Technique
Published 2020-01-01“…The primary outcome was target lesion failure (TLF), a composite of cardiac death, myocardial infarction, and target lesion revascularization (TLR). …”
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1544
Efferocytosis and inflammation: a bibliometric and systematic analysis
Published 2025-02-01“…Keyword analysis identified “activation,” “tam receptors,” “docosahexaenoic acid” “systemic lupus erythematosus,” “myocardial infarction” and “alveolar macrophages” as core topics, indicating a concentrated trend in the mechanism of physiological state and inflammatory diseases such as autoimmune, cardiovascular, and pulmonary diseases. …”
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1545
Randomized controlled trial on effect of different routes of dexmedetomidine on Haemodynamics in patients undergoing saphenectomy under epidural anaesthesia
Published 2025-01-01“…The secondary outcomes were diastolic blood pressure (DBP) and heart rate (HR) at T0 − 8, plasma norepinephrine (NE), myocardial oxygen consumption (MVO2) and anesthesia efficacy. …”
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1546
From bench to bedside: elucidating VEGF(R) inhibitor-related heart failure in cancer treatment
Published 2025-01-01“…Experimental studies in mice revealed that both acute and chronic VEGF(R)i administration resulted in reduced left ventricular EF, cardiomyocyte hypertrophy, and myocardial fibrosis. Transcriptomic analysis identified significant dysregulation of multiple key signaling pathways, including DNA repair (R = 0.46), mitochondrial ATP synthesis (R = 0.39), glycogen metabolism regulation (R = 0.45), and proteasome-mediated protein degradation (R = 0.45). …”
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1547
Composite cardiac computed tomography angiography score for improved risk assessment in chronic coronary syndromes
Published 2025-01-01“…The primary endpoint encompassed all-cause mortality, myocardial infarction, and coronary revascularization (> 60 days after the CCTA scan) during follow-up. …”
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1548
Effects of exercise intensity and diet on cardiac tissue structure and FGF21/β-Klotho signaling in type 2 diabetic mice: a comparative study of HFD and HFD + STZ induced type 2 dia...
Published 2025-01-01“…Additionally, the results of the myocardial tissue qualitative analyses differed between the diabetic mouse models and the ET groups. …”
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1549
Echocardiography indicators in patients with atherosclerosis of peripheral arteries of the lower extremities dependent on T(–786)C polymorphism of the endothelial nitric oxide synt...
Published 2018-03-01“…Results. 54 patients had signs of left ventricular myocardial hypertrophy (LVMH), while in the 2nd group the patients with C allele (p = 0.02) were dominant. …”
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1550
Nationwide observational study of incidence, management and outcome of spontaneous coronary artery dissection: a report from the Swedish Coronary Angiography and Angioplasty regist...
Published 2022-06-01“…Patients with non-SCAD myocardial infarction (MI) (n=32 601) were used for comparison.Outcome measures Outcomes included all-cause mortality, reinfarction or acute coronary reangiography.Results This study found 147 SCAD patients, rendering an incidence of 0.74 per 100 000 per year and a prevalence of 0.43% of all MIs. …”
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1551
A comparison of drug‐eluting stent and coronary artery bypass grafting in mildly to moderately ischemic heart failure
Published 2022-06-01“…Patients with a history of CABG, presented with acute ST‐elevation myocardial infarction (MI) or acute heart failure, and patients who had undergone CABG concomitant valvular or aortic surgery were excluded. …”
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1552
Clinical Characteristics and Outcomes of Elderly Patients Undergoing Primary Percutaneous Coronary Intervention: An Observational Cohort Study
Published 2024-12-01“…Primary percutaneous coronary intervention (pPCI) is the standard of care for ST-elevation myocardial infarction (STEMI) without an upper age limit. …”
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1553
Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model
Published 2025-02-01“…Introduction: Salidroside (SAL), extracted from Rhodiola rosea, has been widely used in coronary heart disease and myocardial ischemia for decades. Previous studies have demonstrated that SAL could reduce arteriosclerosis, and thus combat ischemic brain damage. …”
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1554
Comprehensive profiling of serum microRNAs in normal and non-alcoholic fatty liver disease (NAFLD) patients
Published 2025-01-01“…Furthermore, activation of the miR-122/Sirt-6/ACE2 axis may contribute to myocardial necrosis, highlighting its potential role in NAFLD-associated cardiovascular risks. …”
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1555
Associations of Serum Urate and Cardiovascular Events in a Clinical Trial of Interleukin-1β Blockade
Published 2025-03-01“…Methods: This study is a subanalysis of the Canakinumab Antiinflammatory Thrombosis Outcome Study (CANTOS), which randomized 10,061 patients with prior myocardial infarction and elevated high-sensitivity C-reactive protein to 3 doses of canakinumab or placebo. …”
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1556
The role of oxidized non-coding RNAs of the epigenome in the development of human diseases (literature review)
Published 2023-09-01“…Circulating micro RNAs that are sensitive to oxidative stress are reported to be potential biomarkers of cardiovascular diseases, including myocardial infarction, hypertrophy, ischemia/reperfusion, and heart failure. …”
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1557
Biomimetic Versatile Anisotropic, Electroactive Cellulose Hydrogel Scaffolds Tailored from Fern Stem Serving as Nerve Conduit and Cardiac Patch
Published 2025-01-01“…Abstract Peripheral nerve injury (PNI) and myocardial infarction (MI) are the two most clinically common soft excitable tissue injuries. …”
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1558
Association of C1q/TNF-Related Protein-9 (CTRP9) Level with Obstructive Sleep Apnea in Patients with Coronary Artery Disease
Published 2020-01-01“…From August 2016 to March 2019, consecutive eligible patients with CAD (n=154; angina pectoris, n=88; acute myocardial infarction [AMI], n=66) underwent cardiorespiratory polygraphy. …”
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1559
The Association between Type-2 Diabetes Duration and Major Adverse Cardiac Events after Percutaneous Coronary Intervention
Published 2021-01-01“…A significantly higher rate of myocardial infarction (MI) in diabetic patients with the longest diabetes duration (7.7% vs. 0% and 0.6%, P=0.001) was observed compared with groups of shorter duration. …”
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1560
Monozygotic twins with myocarditis and a novel likely pathogenic desmoplakin gene variant
Published 2020-06-01“…The twins and their family were extensively examined including electrocardiograms (ECG), biochemistry, multimodal cardiac imaging, myocardial biopsy, genetic analysis, repeated cardiac magnetic resonance (CMR) and echocardiography over time. …”
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