DELLA MUTATIONS IN PLANTS WITH SPECIAL EMPHASIS ON WHEAT by G. A. Chebotar, S. V. Chebotar, Yu. M. Sivolap

“…A number of dominant mutations in highly conserved orthologous DELLA genes are known in various plant species. …”
Get full text

IPEX as a Result of Mutations in FOXP3 by Hans J. J. van der Vliet, Edward E. Nieuwenhuis

“…Immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare disorder caused by mutations in the FOXP3 gene that result in the defective development of CD4+CD25+ regulatory T cells which constitute an important T cell subset involved in immune homeostasis and protection against autoimmunity. …”
Get full text

Role of silent mutations in KRAS-mutant tumors by Jun Lu, Chao Zhou, Feng Pan, Hongyu Liu, Haohua Jiang, Hua Zhong, Baohui Han, Xiangxiang Pan

“…Kirsten-RAS (KRAS) mutations, predominantly oncogenic, are pivotal drivers in various cancers. …”
Get full text

Nonmotor Symptoms in Patients with PARK2 Mutations by Asako Yoritaka, Yumi Shimo, Yasushi Shimo, Yuichi Inoue, Hiroyo Yoshino, Nobutaka Hattori

“…Of 12 patients with PARK2 mutations, 4 patients, who were older than patients without abnormal uptake, exhibited decreased MIBG uptake. …”
Get full text

Synergistic effects of mutation and glycosylation on disease progression by Shodai Suzuki, Motoyuki Itoh, Motoyuki Itoh, Motoyuki Itoh

Subjects: Get full text

Pathology and gene mutations of aldosterone-producing lesions by Koshiro Nishimoto, Tadashi Ogishima, Yuki Sugiura, Makoto Suematsu, Kuniaki Mukai

Get full text

Alternate mutation modalities in models of population dynamics by Jonathan Bartlett

“… Most comprehensive simulations of population dynamics use origin-fixation approaches to modeling mutations, specifically modeling mutation using the framework of the modern synthesis. …”
Get full text

The mutational spectrum of NRAS gene discovers a novel frameshift mutation (E49R) in Saudi colorectal cancer patients by Mahmood Rasool, Absarul Haque, Mohammed Alharthi, Abdulrahman Sibiany, Mohammed Saad Alamri, Samer Mohammed Hassan Alqarni, Irfan A. Rather, Adeel G. Chaudhary, Sajjad Karim, Peter Natesan Pushparaj

Subjects: Get full text

A singular limit for an age structured mutation problem by Jacek Banasiak, Aleksandra Falkiewicz

Subjects: “…mutation model…”
Get full text

A mathematical model for treatment-resistant mutations of HIV by Helen Moore, Weiqing Gu

Subjects: Get full text

An Ethic-of-Care Critique of Induced Genetic Mutation in Animals by Josephine Donovan

“… This article proposes an ethic-of-care critique of the current laboratory practice of gene-editing – that is, inducing genetic mutation in animals. An ethic-of-care approach requires taking into consideration the animal’s standpoint or opinion on the procedure. …”
Get full text

Characterization of Somatic Mutations in Malaysian Luminal Breast Cancer by Yock Ping Chow, Ryia Illani Mohd Yunos, Isa Mohd Rose, Norlia Abdullah, Rohaizak Muhammad, Shahrun Niza Abdullah Suhaimi, Saladina Jaszle Jasmin, Norshahidah Mahamad Nadzir, Nurul-Syakima Ab Mutalib, Rahman Jamal

“…PIK3CA is the most frequently mutated gene in our discovery cohort of patients (n=4/9). …”
Get full text

Mutation at the Human D1S80 Minisatellite Locus by Kuppareddi Balamurugan, Martin L. Tracey, Uwe Heine, George C. Maha, George T. Duncan

“…The purpose of this study is to examine repeat mutations from the D1S80 minisatellite locus by sequence analysis to elucidate the mutational process at this locus. …”
Get full text

Environnement et géomatique : des métiers en mutation by Nathalie Vanara, Cécile Huet, Nicolas Payet, Pierre Pech, Lydie Goeldner-Gianella

Get full text

Urticaria unveiled in hereditary angioedema with carboxypeptidase N mutation by Pedro Giavina-Bianchi, MD, PhD, Mara Giavina-Bianchi, MD, PhD, Jorge Kalil, MD, PhD

Get full text

Impact of NRAS Mutations on the Diagnosis of Follicular Neoplasm of the Thyroid by Ja-Seong Bae, Seung Kyu Choi, Sora Jeon, Yourha Kim, Sohee Lee, Youn Soo Lee, Chan Kwon Jung

“…Most patients with a preoperative diagnosis of thyroid follicular neoplasm (FN) undergo diagnostic surgery to determine whether the nodule is benign or malignant. Point mutations at NRAS codon 61 are the most common mutations observed in FN. …”
Get full text

Orders of Magnitude Change in Phenotype Rate Caused by Mutation by Ping Ao

Get full text

Orders of Magnitude Change in Phenotype Rate Caused by Mutation by Peter Duesberg, Ruhong Li, Alice Fabarius, Ruediger Hehlmann

Get full text

Nonfamilial, MPL S505N-Mutated Essential Thrombocythaemia by Ruth Morrell, Stephen E. Langabeer, Liam Smyth, Meegahage Perera, Gerard Crotty

“…Another exon 10 mutation, MPL S505N, has been shown to be a founder mutation in several pedigrees with familial thrombocythaemia where it is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis. …”
Get full text

Multipyrene Tandem Probes for Point Mutations Detection in DNA by Svetlana A. Kholodar, Darya S. Novopashina, Mariya I. Meschaninova, Alya G. Venyaminova

“…Here we report design, synthesis and characterization of highly sensitive, specific and stable in biological systems fluorescent probes for point mutation detection in DNA. The tandems of 3′- and 5′-mono- and bis-pyrene conjugated oligo(2′-O-methylribonucleotides), protected by 3′-“inverted” thymidine, were constructed and their potential as new instruments for genetic diagnostics was studied. …”
Get full text