Los mutantes de la escuela by Diego Armando Jaramillo-Ocampo, Napoleón Murcia-Peña

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Ovarian Abnormalities in the Staggerer Mutant Mouse by Jean-Marie Guastavino, Salima Boufares, Wim E. Crusio

“…These results indicate a pleiotropic effect on fertility of the Rorasg gene underlying the cerebellar abnormalities of the staggerer mutant.…”
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Role of silent mutations in KRAS-mutant tumors by Jun Lu, Chao Zhou, Feng Pan, Hongyu Liu, Haohua Jiang, Hua Zhong, Baohui Han, Xiangxiang Pan

“…Moreover, investigations into the clinical implications of silent mutations in KRAS-mutant tumors suggest potential diagnostic and therapeutic strategies. …”
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Histological Characterization of the Dicer1 Mutant Zebrafish Retina by Saeed Akhtar, Sarita Rani Patnaik, Rakesh Kotapati Raghupathy, Turki M. Al-Mubrad, John A. Craft, Xinhua Shu

“…In this study, we characterized a Dicer1 mutant fish line, which carries a nonsense mutation (W1457Ter) induced by N-ethyl-N-nitrosourea mutagenesis. …”
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Mutant glycosidases for labeling sialoglycans with high specificity and affinity by Shuyu Liang, Qi Tang, Xunzi Guo, Zi’an Li, Yilan Guo, Jinghan Chang, Bo Cheng, Qitao Song, Jiayu Sun, Peng Dai, Xing Chen

“…Here we report the development of glycan recombinant affinity binders (GRABs) based on mutant bacterial sialidases, which are enzymatically inactive but preserve stringent specificity for sialoglycan substrates. …”
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EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia by Álvaro Taus, Flavio Zuccarino, Carlos Trampal, Edurne Arriola

“…We present a case of a 77-year-old man with an initial PET-CT scan showing high 18F-FDG intake, suggesting a bilateral pneumonia, who was finally diagnosed of an EGFR-mutant lung adenocarcinoma. EGFR-activating mutation allowed us to start treatment with the oral tyrosin kinase inhibitor Gefitinib, obtaining a rapid and sustained response. …”
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IDH Mutant Cholangiocarcinoma: Pathogenesis, Management, and Future Therapies by Alexander Bray, Vaibhav Sahai

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Navigating the Evolving Treatment Paradigm for _EGFR_-Mutant NSCLC by Sebastian Kraus

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The relationship between IDH, P53 mutations, MGMT methylation with characteristics in high grade glioma patients by Duc Anh Tran, Ba Van Nguyen, Bac Thanh Nguyen, Hoe Van Vu, Lien Duc Nguyen

Subjects: “…mutant IDH…”
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Lens Extrusion from Laminin Alpha 1 Mutant Zebrafish by Mallika Pathania, Elena V. Semina, Melinda K. Duncan

“…We report analysis of the ocular lens phenotype of the recessive, larval lethal zebrafish mutant, lama1a69/a69. Previous work revealed that this mutant has a shortened body axis and eye defects including a defective hyaloid vasculature, focal corneal dysplasia, and loss of the crystalline lens. …”
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Oncogenic mutant KRAS inhibition through oxidation at cysteine 118 by Maximilian Kramer‐Drauberg, Ettore Petrini, Alessia Mira, Enrico Patrucco, Rossella Scardaci, Ilenia Savinelli, Haiyun Wang, Keying Qiao, Giovanna Carrà, Marie‐Julie Nokin, Zhiwei Zhou, Kenneth D. Westover, David Santamaria, Paolo E. Porporato, Chiara Ambrogio

“…Our study shows for the first time the vulnerability of human mutant KRAS to oxidation, thereby paving the way to explore oxidation‐based anti‐KRAS treatments in humans.…”
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STUDY OF THE THERMAL STABILITY OF BARNASE PROTEIN MUTANTS WITH MOLKERN SOFTWARE by E. S. Fomin, N. A. Alemasov

“…A thermal stability study of several barnase mutants has been carried out by the λ dynamics method. …”
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Comprehensive evaluation of spring barley mutants according to their yield components by A. A. Belozerova, D. A. Bazyuk, N. A. Bome

“…Mutant plant samples with stable manifestation of those traits, irrespective of the growing season conditions, were selected. …”
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Fixation Probabilities of Evolutionary Graphs Based on the Positions of New Appearing Mutants by Pei-ai Zhang

“…However the position of the new mutant is important to its fixation probability. Here the position of the new mutant is laid emphasis on. …”
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IDH-mutant gliomas in children and adolescents - from biology to clinical trials by Louise Evans, Sarah Trinder, Sarah Trinder, Andrew Dodgshun, Andrew Dodgshun, David D. Eisenstat, David D. Eisenstat, David D. Eisenstat, James R. Whittle, James R. Whittle, James R. Whittle, Jordan R. Hansford, Jordan R. Hansford, Jordan R. Hansford, Santosh Valvi, Santosh Valvi, Santosh Valvi

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STUDY OF SYMBIOSIS FORMATION CONTROL IN PEA MUTANTS BY THE VEGETATIVE GRAFT METHOD by E. Yu. Vlasova, K. K. Sidorova, M. N. Glyanenko, T. M. Mishchenko

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Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy by Mafalda Bacalhau, Filipa C. Ferreira, Marcelo Folhadella M. F. Azevedo, Talita P. Rosa, Camilla D. Buarque, Miquéias Lopes-Pacheco

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Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin by Jeonghyun Oh, Christy Catherine, Eun Seon Kim, Kwang Wook Min, Hae Chan Jeong, Hyojin Kim, Mijin Kim, Seung Hae Ahn, Nataliia Lukianenko, Min Gu Jo, Hyeon Seok Bak, Sungsu Lim, Yun Kyung Kim, Ho Min Kim, Sung Bae Lee, Hyunju Cho

“…Using yeast toxicity-based screening with a random mutant library, we identify two yeast PEX19 variants and engineer equivalent mutations into human PEX19 (hsPEX19). …”
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The Mutant Problem: X-Men, Confirmation Bias, and the Methodology of Comics and Identity by Martin Lund

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Neratinib as a Potential Therapeutic for Mutant RAS and Osimertinib-Resistant Tumours by Paul Dent, Laurence Booth, Andrew Poklepovic, John F. Hancock

“…Neratinib rapidly disrupted mutant RAS nanoclustering, which was followed by mutant rat sarcoma virus proteins translocating via LC3-associated phagocytosis into the cytosol where they were degraded by macroautophagy. …”
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