Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson’s Disease Patients by William Haylett, Chrisna Swart, Francois van der Westhuizen, Hayley van Dyk, Lize van der Merwe, Celia van der Merwe, Ben Loos, Jonathan Carr, Craig Kinnear, Soraya Bardien

“…However, published results reporting on patient-derived parkin-mutant fibroblasts have been inconsistent. This study aimed to functionally compare parkin-mutant fibroblasts from PD patients with wild-type control fibroblasts using a variety of assays to gain a better understanding of the role of mitochondrial dysfunction in PD. …”
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Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer by Soomin Kim, Jaemoon Koh, Tae Min Kim, Songji Oh, Soyeon Kim, Jeonghwan Youk, Miso Kim, Bhumsuk Keam, Yoon Kyung Jeon, Dong-Wan Kim, Dae Seog Heo

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Mutagenesis and Identification of Sugarcane Mutants Using Survival on Polyethylene Glycol and Leaf Damage under Managed Water Stress by Napa Weksanthia, Tanapon Chaisan, Wannasiri Wannarat, Songyos Chotchutima, Peeranuch Jompuk

“…Both healthy mutant sugarcane plants (2,086) and non-mutant plants (234) were cultured on the media with 20% PEG for 16 weeks. …”
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Mutant Prevention Concentrations of Doripenem and Meropenem Alone and in Combination with Colistin (Polymyxin E), Levofloxacin and Tobramycin in Pseudomonas aeruginosa by George G Zhanel, Vibhu Vishisht, Ed Tam, Daryl J Hoban, James A Karlowsky

“…In the present study, the mutant prevention concentration (MPC) of doripenem was examined and compared with meropenem for its ability to prevent resistant mutant selection for P aeruginosa when used alone and in combination with the other antipseudomonal agents colistin (polymyxin E), levofloxacin and tobramycin. …”
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Naturally Occurring Hepatitis B Virus B-Cell and T-Cell Epitope Mutants in Hepatitis B Vaccinated Children by Yu-Min Lin, Guey-Mei Jow, Shu-Chi Mu, Bing-Fang Chen

“…Several immune-epitope mutants, such as S45T/A, N131T, I194V, and S207N in S, were detected in all isolates. …”
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A Case Presentation of a Patient with Microsatellite Instability and BRAF Mutant Metastatic Colon Cancer and Bibliography Update by K. Thomopoulou, M. Tzardi, D. Mavroudis, I. Souglakos

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Changes in the content of proteins and lipids and in the state of the antioxidant system in mutant forms of <i>Amaranthus cruentus</i> L. by R. M. Taipova, V. N. Nesterov, O. A. Rozentsvet, B. R. Kuluev

“…An increase in salt tolerance compared to the control was observed in mutants No. 2 and No. 3. Mutant No. 2 under salinization demonstrated higher peroxidase activity and mutant No. 3 higher catalase activity; both mutants showed a reduced rate of superoxide anion formation compared to the control.Conclusion. …”
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Marker-Assisted Selection for Recognizing Wheat Mutant Genotypes Carrying HMW Glutenin Alleles Related to Baking Quality by Mohammad Javad Zamani, Mohammad Reza Bihamta, Behnam Naserian Khiabani, Zahra Tahernezhad, Mohammad Taher Hallajian, Marzieh Varasteh Shamsi

“…It showed that mutation had effect on the amount of seed storage protein on the mutant seeds (which showed polymorphism).…”
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Assessment of the quality of life in metastatic colorectal cancer patients with KRAS gene mutant: a case-control study by Fahmideh Bagrezaei, Bahram Pourghassem Gargari, Reza Eghdam Zamiri, Abdolrasoul Safaiyan, Mohammad Alizadeh

“…This research investigated the association between KRAS mutant status and various aspects of QOL in mCRC patients. …”
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Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SS^LepR Mutant Rats? by Abdulmohsin Alhashim, Kim Capehart, Jocelyn Tang, Karim M. Saad, Rafik Abdelsayed, Marion A. Cooley, Jan M. Williams, Ahmed A. Elmarakby

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Variation of fatty acid composition in seed oil in the collection of induced oil flax (Linum humile Mill.) mutants by A. V. Tigova, A. I. Soroka

“…The statistical analysis showed significant distinctions between the mutant lines in the biochemical composition of the oil. …”
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Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants by Steven J. Smith, Xue Zhi Zhao, Stephen H. Hughes, Terrence R. Burke

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The role of plastid genes in a heterosis effect and the formation of morphophysiological traits in sunflower plants by A. V. Usatov, M. S. Makarenko, A. A. Kovalevich, A. М. Gubaidullina

Subjects: “…chlorophyll mutants…”
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Studies on mutagenic effect of phosphemide in barley by N. V. Tetyannikov, N. A. Bome

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Variation in mitochondrial genome primary sequence among whole-genome-sequenced strains of Neurospora crassa by K. McCluskey

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Real-world data of dacomitinib as first-line treatment for patients with EGFR-mutant non-small-cell lung cancer by Ji Eun Shin, Hyun Ae Jung, Sehhoon Park, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Byoung Yong Shim

Subjects: “…Epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC)…”
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Mutant Prevention Concentration of Ciprofloxacin against Klebsiella pneumoniae Clinical Isolates: An Ideal Prognosticator in Treating Multidrug-Resistant Strains by B. Aditi Priyadarshini, Krishnan Mahalakshmi, Venkatesan Naveen Kumar

“…Fluoroquinolone-resistant Klebsiella pneumoniae poses a therapeutic challenge when implicated in urinary tract infections, pyelonephritis, pneumonia, skin infections, osteomyelitis, and respiratory infections. The mutant prevention concentration (MPC) represents a concentration threshold above which increase of resistant mutants occurs rarely. …”
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Tetrahydroxy Cyclic Urea-Potent Inhibitor for HIV-1 Protease Wild Type and Mutant Type—A Computational Design by S. Sree Kanth, M. Vijjulatha

“…The designed molecules were compared with the known cyclic urea molecules by performing docking studies on six of wild type protein and three mutant protein varieties and calculating their ADME properties. …”
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Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway by Xing Luo, Yi Duan, Jinwei He, CongGai Huang, Jun Liu, Yifan Liu, Mengdei Xu, Qiong Dai, Zhihui Yang

“…Combining DHT, BRAF inhibitors, and MEK inhibitors can help treat treatment-resistant BRAF mutant melanoma cells. Experimental results both in vitro and in vivo have shown that the combination of DHT and an inhibitor of the MAPK pathway is safer and more successful than using an inhibitor of the MAPK pathway alone when treating BRAF mutant melanoma.…”
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Establishment of a Mutant Library for Infection Cushion Development and Identification of a Key Regulatory Gene in <i>Botrytis cinerea</i> by Maoyao Tang, Kexin Wang, Pan Zhang, Jie Hou, Xiaoqian Yu, Hongfu Wang, Yangyizhou Wang, Guihua Li

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