Significados permanentes e mutantes: sociabilidades e significações no cotidiano de um café by Letícia Dias Fantinel, Neusa Rolita Cavedon, Tânia Maria Diederichs Fischer

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LEA Gene Expression Assessment in Advanced Mutant Rice Genotypes under Drought Stress by Zarifth Shafika Kamarudin, Mohd Rafii Yusop, Mohd Razi Ismail, Mahmud Tengku Muda Mohamed, Abdul Rahim Harun, Oladosu Yusuff, Usman Magaji, Arolu Fatai

“…This indicates that these advanced mutant genotypes have better tolerance to drought stress. …”
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Elucidating the effects of manganese on the growth and cadmium accumulation of OsNRAMP5 mutant rice by Xian’an Yu, Qiuqin Zhou, Xin-Yuan Huang, Mingxue Chen, Jiawen Zhou, Tong Zhou, Pengjie Hu, Xia Pan, Miaomiao Cheng, Yongming Luo, Peter Christie, Longhua Wu

“…Here, hydroponics and pot experiments were used to investigate the growth and Cd accumulation of an OsNRAMP5 mutant rice, Zhong’an 7 (ZA7), and the wild type, Zhongzao 35 (ZZ35), under different Mn supply conditions, and the Mn thresholds for ZA7 were determined. …”
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Drosophila Mutant Model of Parkinson’s Disease Revealed an Unexpected Olfactory Performance: Morphofunctional Evidences by Francescaelena De Rose, Valentina Corda, Paolo Solari, Patrizia Sacchetti, Antonio Belcari, Simone Poddighe, Sanjay Kasture, Paolo Solla, Francesco Marrosu, Anna Liscia

“…In spite of the above reported results, the behavioural response to olfactory stimuli in mutant flies is impaired compared to that obtained in wild type flies. …”
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Induced protein expression in Leptospira spp. and its application to CRISPR/Cas9 mutant generation by L. G. V. Fernandes, A. L. T. O. Nascimento, J. E. Nally

“…This system was applied for regulated expression of dead Cas9 (dCas9) to generate knockdown mutants, and Cas9 to produce knockout mutants by inducing double-strand breaks (DSB) into desired targets. …”
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Genetic diversity and population structure of cowpea mutant collection using SSR and ISSR molecular markers by Sara Diallo, François Abaye Badiane, Badji-N’Poneh Ange Kabkia, Issa Diédhiou, Made Diouf, Diaga Diouf

Subjects: “…Cowpea mutants…”
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Gemistocytic tumor cells programmed for glial scarring characterize T cell confinement in IDH-mutant astrocytoma by Levi van Hijfte, Marjolein Geurts, Iris de Heer, Santoesha A. Ghisai, Hayri E. Balcioglu, Youri Hoogstrate, Wies R. Vallentgoed, Rania Head, Rosa Luning, Thierry van den Bosch, Bart Westerman, Pieter Wesseling, Johanna A. Joyce, Pim French, Reno Debets

“…Abstract Isocitrate dehydrogenase 1/2 mutant (IDHmt) astrocytoma is considered a T cell-deprived tumor, yet little is known regarding the phenotypes underlying T cell exclusion. …”
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Hsp90 mutants with distinct defects provide novel insights into cochaperone regulation of the folding cycle. by Rebecca Mercier, Danielle Yama, Paul LaPointe, Jill L Johnson

“…Here we used those mutants to dissect Hsp90 and cochaperone interactions. …”
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Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability by Valerie Haller, Carina Reiff, Rainer Hamacher, Karina Kostbade, Moritz Kaths, Juergen Treckmann, Stefanie Bertram, Yasmin Zaun, Sebastian Bauer, Johanna Falkenhorst

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PluxI mutants with different promoting period and their application for quorum sensing regulated protein expression by Zhuoning Cao, Zhen Liu, Guilin Zhang, Xiangzhao Mao

“…Therefore, the PluxI mutants with different promoting periods and/or different strengths show great potential in both laboratory and industrial scale for protein expression.…”
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Lack of GAGA protein in Trl mutants causes massive cell death in Drosophila spermatogenesis and oogenesis by N. V. Dorogova, A. E. Zubkova, E. V. Fedorova, E. U. Bolobolova, E. M. Baricheva

“…Thus, GAF lack in Trl mutants leads to increased germ cell death through apoptosis and autophagy. …”
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Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease by Mahdi Bagherpoor Helabad, Irina Matlahov, Raj Kumar, Jan O. Daldrop, Greeshma Jain, Markus Weingarth, Patrick C. A. van der Wel, Markus S. Miettinen

“…Abstract Neurodegeneration in Huntington’s disease (HD) is accompanied by the aggregation of fragments of the mutant huntingtin protein, a biomarker of disease progression. …”
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Distinct cellular toxicity of two mutant huntingtin mRNA variants due to translation regulation. by Haifei Xu, Juan Ji An, Baoji Xu

“…To assay roles of two HTT mRNA variants in cell bodies, we expressed mRNA harboring HTT exon1 containing 23x or 145x CAGs with the short or long 3'UTR. We found that mutant mRNA containing the short 3'UTR produced more protein aggregates and caused more apoptosis in both cultured neurons and HEK293 cells, compared with mutant mRNA containing the long 3'UTR. …”
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A New gcrR-Deficient Streptococcus mutans Mutant for Replacement Therapy of Dental Caries by Wenting Pan, Tiantian Mao, Qing-an Xu, Jin Shao, Chang Liu, Mingwen Fan

“…S. mutans UA159 and the mutant MS-gcrR-def were inoculated, respectively, or together for competitive testing in vitro and in rat model. …”
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Phytoalexin deficient 4 is associated with the lesion mimic trait in watermelon clalm mutant (Citrullus lanatus) by Jiale Shi, Congji Yang, Yuanyuan Qin, Qingqing Liu, Shengqi Hua, Defeng Wu, Wei Dong

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Targeting KRAS‐mutant pancreatic cancer through simultaneous inhibition of KRAS, MEK, and JAK2 by Satoru Miyazaki, Masato Kitazawa, Satoshi Nakamura, Makoto Koyama, Yuta Yamamoto, Nao Hondo, Masahiro Kataoka, Hirokazu Tanaka, Michiko Takeoka, Daisuke Komatsu, Yuji Soejima

“…Accordingly, simultaneous inhibition of KRAS, MEK, and JAK2 could be an innovative therapeutic strategy against KRAS‐mutant pancreatic cancer.…”
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BRAF mutant appendiceal adenocarcinoma differs from colorectal cancer but responds to BRAF-targeted therapy by Vinay K. Pattalachinti, Emaan Haque, Mahmoud Yousef, Abdelrahman Yousef, Saikat Chowdhury, Michael Overman, Christine M. Parseghian, Van K. Morris, Bryan Kee, Ryan W. Huey, Kanwal Raghav, Colin M. Court, John Paul Shen

“…Here, we retrospectively compare BRAF-mutant AA and colorectal cancer (CRC). BRAF mutation is rare in AA (3%). …”
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Salvage pathway of vitamin B12 absorption in chickens with mutant tumor virus a receptor by Yun Ji Shin, Jin-Kyoo Kim, Seung Je Woo, Byung Chul Park, Jae Yong Han

“…These results suggest a mechanism by which mutant TVA chickens with a disrupted TVA protein acquire natural resistance to ALV-A -K, with no impairment of vitamin B12 metabolism.…”
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Homozygous mice with mutant protein FUS[1-359] overexpression: Innovative possibilities for ALS treatment by Nikita S. Zhunusov

“…Introduction: This study investigates a mouse model with overexpression of the mutant FUS[1-359] protein, which can be used to evaluate the effectiveness of gene therapy and other pharmacological interventions for amyotrophic lateral sclerosis (ALS). …”
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Principal component analysis (PCA) as a genetic diversity tool to understand the variation of rice mutant culture by S. Palaniyappan1, P. Arunachalam1*, S. Banumathy1 and S. Muthuramu2

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