Lack of GAGA protein in Trl mutants causes massive cell death in Drosophila spermatogenesis and oogenesis by N. V. Dorogova, A. E. Zubkova, E. V. Fedorova, E. U. Bolobolova, E. M. Baricheva

“…Thus, GAF lack in Trl mutants leads to increased germ cell death through apoptosis and autophagy. …”
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A New gcrR-Deficient Streptococcus mutans Mutant for Replacement Therapy of Dental Caries by Wenting Pan, Tiantian Mao, Qing-an Xu, Jin Shao, Chang Liu, Mingwen Fan

“…S. mutans UA159 and the mutant MS-gcrR-def were inoculated, respectively, or together for competitive testing in vitro and in rat model. …”
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Phytoalexin deficient 4 is associated with the lesion mimic trait in watermelon clalm mutant (Citrullus lanatus) by Jiale Shi, Congji Yang, Yuanyuan Qin, Qingqing Liu, Shengqi Hua, Defeng Wu, Wei Dong

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Targeting KRAS‐mutant pancreatic cancer through simultaneous inhibition of KRAS, MEK, and JAK2 by Satoru Miyazaki, Masato Kitazawa, Satoshi Nakamura, Makoto Koyama, Yuta Yamamoto, Nao Hondo, Masahiro Kataoka, Hirokazu Tanaka, Michiko Takeoka, Daisuke Komatsu, Yuji Soejima

“…Accordingly, simultaneous inhibition of KRAS, MEK, and JAK2 could be an innovative therapeutic strategy against KRAS‐mutant pancreatic cancer.…”
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BRAF mutant appendiceal adenocarcinoma differs from colorectal cancer but responds to BRAF-targeted therapy by Vinay K. Pattalachinti, Emaan Haque, Mahmoud Yousef, Abdelrahman Yousef, Saikat Chowdhury, Michael Overman, Christine M. Parseghian, Van K. Morris, Bryan Kee, Ryan W. Huey, Kanwal Raghav, Colin M. Court, John Paul Shen

“…Here, we retrospectively compare BRAF-mutant AA and colorectal cancer (CRC). BRAF mutation is rare in AA (3%). …”
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Principal component analysis (PCA) as a genetic diversity tool to understand the variation of rice mutant culture by S. Palaniyappan1, P. Arunachalam1*, S. Banumathy1 and S. Muthuramu2

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Synergetic effect of fungal pretreatment and lignin modification on delignification and saccharification: a case study of a natural lignin mutant in mulberry by James Paul T. Madigal, Masami Terasaki, Masatsugu Takada, Shinya Kajita

Subjects: “…Lignin mutant…”
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BRAF Inhibitors for BRAF V600E Mutant Colorectal Cancers: Literature Survey and Case Report by Yasar Subutay Peker, Mehmet Fatih Can, Ismail Hakki Ozerhan, Gokhan Yagci, Nazif Zeybek, Kutan Kavakli, Sedat Gurkok, Alper Gozubuyuk, Onur Genc, Gokhan Erdem, Ahmet Ozet, Mustafa Gerek, Yusuf Peker

“…BRAF inhibitors, which are accepted as standard treatment for V600E mutant malign melanomas, are the newest approach for targeted treatment of V600E mutant colorectal cancers. …”
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Advanced mutant receptor activator of nuclear factor kappa‐Β ligand development with low affinity for osteoprotegerin by Yuria Jang, Yongjin Cho, Youngjong Ko, Yeonhee Moon, Chang‐Moon Lee, Wonbong Lim

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CYTOLOGICAL AND GENETIC CHARACTERIZATION OF A NEW MUTANT OF VEGETABLE PEPPER CAPSICUM ANNUUM VAR. ANNUUM L. by O. Yu. Timin, O. O. Timina, P. Yu. Montvid, A. P. Samovol

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The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice by Lu Zhang, Li Chen, Xuqiang Zhang, Yang Li, Qingfeng Zheng, Yun Li, Ning Li, Qiumei Shi, Yanying Zhang, Tonglei Wu

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A software module to assess the metabolic potential of mutant strains of the bacterium <i>Corynebacterium glutamicum</i> by F. V. Kazantsev, M. F. Trofimova, T. M. Khlebodarova, Yu. G. Matushkin, S. A. Lashin

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Correction: Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability by Valerie Haller, Carina Reiff, Rainer Hamacher, Karina Kostbade, Moritz Kaths, Juergen Treckmann, Stefanie Bertram, Yasmin Zaun, Sebastian Bauer, Johanna Falkenhorst

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Safety and immunogenicity in humans of enterotoxigenic Escherichia coli double mutant heat-labile toxin administered intradermally by Marcela F. Pasetti, Patricia L. Milletich, Jessica A. White, Jessica Butts, Rebecca C. Brady, Michelle D. Dickey, Cassandra Ballou, Nicole Maier, Marcelo B. Sztein, Shahida Baqar, A. Louis Bourgeois, David I. Bernstein

“…A Phase 1, double-blind, dose-escalation (0.1-2.0 µg) study was conducted to evaluate the safety and immunogenicity of double mutant heat-labile toxin LTR192G/L211A (dmLT) delivered intradermally (ID) to healthy adults. …”
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Anthracyclines disaggregate and restore mutant p63 function: a potential therapeutic approach for AEC syndrome by Fabiana Boncimino, Ludovica D’Auria, Kristina Todorova, Sabina Y. van der Zanden, Jacques Neefjes, Anna Mandinova, Caterina Missero, Stefano Sol

“…Our findings identify compounds that can partially resolve mutant p63 aggregation, increase its monomeric isoform, and reactivate its transcriptional function. …”
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Common vetch (<i>Vicia sativa</i>) multi-podded mutants for enhanced commercial seed production by Aleksandar Mikić, Vojislav Mihailović, Đura Karagić, Branko Milošević, Dragan Milić, Sanja Vasiljević, Snežana Katanski, Dalibor Živanov

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Derivation and Characterization of Isogenic <i>OPA1</i> Mutant and Control Human Pluripotent Stem Cell Lines by Katherine A. Pohl, Xiangmei Zhang, Johnny Jeonghyun Ji, Linsey Stiles, Alfredo A. Sadun, Xian-Jie Yang

“…In comparison to the isogenic controls, the heterozygous mutant PSCs expressed the same OPA1 protein isoforms but at reduced levels; whereas the homozygous mutant PSCs showed a loss of OPA1 protein and altered mitochondrial morphology. …”
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Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report by Hannah Haile, Pavan S. Upadhyayula, Esma Karlovich, Michael B. Sisti, Brian J. A. Gill, Laura E. Donovan

“…In this case report, we describe the management of a 67-year-old male with BRAFV600E -mutant GBM, who experienced both local clonal and distant non-clonal BRAFV600E -mutant recurrences. …”
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A Novel P53-Related Activity in a Colon Adenocarcinoma Cell Line With Mutant P53 by Andrei L. Gartel, Eugene Goufman, Charlotte Hurth, Angela L. Tyner

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Identification of Potential Calorie Restriction-Mimicking Yeast Mutants with Increased Mitochondrial Respiratory Chain and Nitric Oxide Levels by Bin Li, Craig Skinner, Pablo R. Castello, Michiko Kato, Erin Easlon, Li Xie, Tianlin Li, Shu-Ping Lu, Chen Wang, Felicia Tsang, Robert O. Poyton, Su-Ju Lin

“…Analysis of the top 17 mutants demonstrates a correlation between increased NO, mitochondrial respiration, and longevity. …”
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