Identification of C-Kit-Positive Interstitial Cells in the Dog Lower Urinary Tract and Relationship with Smooth Muscle and Nerves. Hypotheses for a Likely Pacemaker Role. by Silvana Arrighi, Giampaolo Bosi, Debora Groppetti, Fausto Cremonesi

“…The relationship with antiactin positive smooth muscle cells and PGP9.5-positive intramural innervation was also investigated by confocal microscopy. …”
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Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential by Sun Jeong Kim, Sang Eon Park, Jang Bin Jeong, Shin Ji Oh, Alee Choi, Yun Hee Kim, Suk-joo Choi, Soo-young Oh, Gyu Ha Ryu, Hong Bae Jeon, Jong Wook Chang

“…Moreover, AURKA from human WJ-MSCs regulated the antiapoptotic effect of skeletal muscle cells by upregulating the chemokine (C motif) ligand (XCL1); this was further confirmed in the mdx mouse model. …”
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The Use of Regenerative Medicine in the Management of Invasive Bladder Cancer by Matthew E. Hyndman, Deborah Kaye, Nicholas C. Field, Keith A. Lawson, Norm D. Smith, Gary D. Steinberg, Mark P. Schoenberg, Trinity J. Bivalacqua

“…Clinical trials using neourinary conduits (NUC) seeded with autologous smooth muscle cells are currently in progress and may represent a significant surgical advance, potentially eliminating the complications associated with the use of gastrointestinal segments in the urinary reconstruction, simplifying the surgical procedure, and greatly facilitating recovery from cystectomy.…”
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Predicting oxytocin binding dynamics in receptor genetic variants through computational modeling by Preeti Dubey, Yingye Fang, K. Lionel Tukei, Shobhan Kuila, Xinming Liu, Annika Sahota, Antonina I. Frolova, Erin L. Reinl, Manasi Malik, Sarah K. England, Princess I. Imoukhuede

“…To address this, we developed a mathematical model examining the effects of five OXT receptor (OXTR) variants (V45L, P108A, L206V, V281M, and E339K) on OXT–OXTR binding dynamics in human embryonic kidney cells (HEK293T) and myometrial smooth muscle cells. The model was parameterized using experimentally derived, cell-specific OXTR surface localization measurements and literature-reported OXT-OXTR-binding kinetics. …”
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Caffeine's Vascular Mechanisms of Action by Darío Echeverri, Félix R. Montes, Mariana Cabrera, Angélica Galán, Angélica Prieto

“…Nitric oxide is diffused to the vascular smooth muscle cell to produce vasodilation. In vascular smooth muscle cells its effect is predominantly a competitive inhibition of phosphodiesterase, producing an accumulation of cAMP and vasodilation. …”
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Isoliquiritigenin Inhibits Atherosclerosis by Blocking TRPC5 Channel Expression by Jie Qi, Jianguo Cui, Baobin Mi, Xiaohong Yan, Wenwen Xu, Hui Ma, Qingtan Zhang, Fang Xu

“…In this study, we used apolipoprotein E (ApoE) knockout mouse model and angiotensin II- (Ang II-) stimulated vascular smooth muscle cells (VSMCs) to elucidate the pharmacological mechanism of ISL to inhibit atherosclerosis. …”
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Intravascular Leiomyomatosis as a Rare Cause of Nonthrombotic Pulmonary Embolism by Julie Van Maercke, Anne-Sophie Van Rompuy, Willy Poppe, Tom Verbelen, Marion Delcroix, Catharina Belge

“…It is characterized by the proliferation of benign smooth muscle cells within vascular structures without invasion of these tissues. …”
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Vasorelaxant effects and its mechanisms of the rhizome of Acorus gramineus on isolated rat thoracic aorta by Jueon Lee, Sujin Shin, Junkyu Park, Ho-Young Choi, Kyungjin Lee

“…The findings suggested that the mechanism of this effect was independent of endothelial cells and was associated with vascular smooth muscle cells (VSMC). Since vasodilatory mechanisms associated with VSMC are predominantly influenced by K+ and Ca2+ channels, we explored various channels, including calcium-activated K+, voltage-dependent (delayed rectifier) K+, ATP-sensitive K+, inwardly rectifying K+, receptor-operated Ca2+ (ROCC), and voltage-dependent Ca2+ channels (VDCC). …”
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Mesenchymal Stem Cells Combined with Tissue Fusion Technology Promoted Wound Healing in Porcine Bowel Anastomosis by Hong Pan, Ping Keun Lam, See W. Tong, Kevin K. Leung, Anthony Y. Teoh, Enders K. Ng

“…Labeled MSCs were found in the mucosal layer, villus, and lamina propria, as well as in the lamina muscularis mucosae, where they exhibited characteristics of smooth muscle cells. Conclusions. Grafted MSCs significantly promoted epithelial and connective cell proliferation and maintained their cell migration capacity and differentiation potential in the fused anastomotic tissues, without causing severe postoperative complications.…”
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Dulaglutide Protects Mice against Diabetic Sarcopenia-Mediated Muscle Injury by Inhibiting Inflammation and Regulating the Differentiation of Myoblasts by Fengyi Deng, Wenyan Wu, Xingyu Fan, Xing Zhong, Nuojin Wang, Yue Wang, Tianrong Pan, Yijun Du

“…Moreover, C2C12 cells were induced to enable their differentiation into skeletal muscle cells, and muscle factor levels were then detected. …”
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Changing of expression actinbinding proteins in the kidney under dehydration by I. I. Khegay

“…The constant reorganization of actin cytoskeleton takes place in non-muscle cells. Fibrillar actin, organized by globular monomers, interacts with the actin-binding proteins. …”
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Photofunctional Co-Cr Alloy Generating Reactive Oxygen Species for Photodynamic Applications by Kang-Kyun Wang, Bong-Jin Kim, Mi Hee Lee, Byeong-Ju Kwon, Dong Hoon Choi, Jong-Chul Park, Yong-Rok Kim

“…To open the possibility for its application as a photodynamic material to biological system, the fabricated photofunctional Co-Cr alloy is applied to the decomposition of smooth muscle cells.…”
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Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling by Qishan Chen, Min Jin, Feng Yang, Jianhua Zhu, Qingzhong Xiao, Li Zhang

“…During angiogenesis and vascular remodeling, behaviors of stem/progenitor cells, endothelial cells (ECs), and vascular smooth muscle cells (VSMCs) and its interaction with extracellular matrix (ECM) play a critical role in the processes. …”
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Comparative and Developmental Anatomy of Cardiac Lymphatics by A. Ratajska, G. Gula, A. Flaht-Zabost, E. Czarnowska, B. Ciszek, E. Jankowska-Steifer, J. Niderla-Bielinska, D. Radomska-Lesniewska

“…In most mammalian species the collectors run along major branches of coronary arteries, have valves and a discontinuous layer of smooth muscle cells.…”
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In Vitro Differentiation of First Trimester Human Umbilical Cord Perivascular Cells into Contracting Cardiomyocyte-Like Cells by Peter Szaraz, Matthew Librach, Leila Maghen, Farwah Iqbal, Tanya A. Barretto, Shlomit Kenigsberg, Andrée Gauthier-Fisher, Clifford L. Librach

“…Myocardial infarction (MI) causes an extensive loss of heart muscle cells and leads to congestive heart disease (CAD), the leading cause of mortality and morbidity worldwide. …”
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GLP-1 Relaxes Rat Coronary Arteries by Enhancing ATP-Sensitive Potassium Channel Currents by Qian-Feng Xiong, Shao-Hua Fan, Xue-Wen Li, Yu Niu, Jing Wang, Xin Zhang, Yi-Fan Chen, Ya-Wei Shi, Li-Hui Zhang

“…Furthermore, GLP-1 increased outward K+ currents by enhancing the KATP channel in rat coronary arterial smooth muscle cells (RCASMCs). These results show that GLP-1 is an endothelial-dependent vasospasmolytic agent in the RCA and imply that the relaxant effect is regulated by enhancing KATP rather than KV or KCa currents in RCASMCs.…”
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Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes by Chunzi Liang, Benjamin J. Curry, Patricia L. Brown, Michael B. Zemel

“…Previous studies from this laboratory demonstrate that dietary leucine protects against high fat diet-induced mitochondrial impairments and stimulates mitochondrial biogenesis and energy partitioning from adipocytes to muscle cells through SIRT1-mediated mechanisms. Moreover, β-hydroxy-β-methyl butyrate (HMB), a metabolite of leucine, has been reported to activate AMPK synergistically with resveratrol in C2C12 myotubes. …”
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An Alternative Method for Long-Term Culture of Chicken Embryonic Stem Cell In Vitro by Li Zhang, Yenan Wu, Xiang Li, Shao Wei, Yiming Xing, Zhengxing Lian, Hongbing Han

“…These cells also exhibited the capability to differentiate into cardiac myocytes, smooth muscle cells, neural cells, osteoblast, and adipocyte in vitro. …”
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Does Branched-Chain Amino Acids Supplementation Modulate Skeletal Muscle Remodeling through Inflammation Modulation? Possible Mechanisms of Action by Humberto Nicastro, Claudia Ribeiro da Luz, Daniela Fojo Seixas Chaves, Luiz Roberto Grassmann Bechara, Vanessa Azevedo Voltarelli, Marcelo Macedo Rogero, Antonio Herbert Lancha

“…The proinflammatory status of muscle cells, observed in pathological conditions such as cancer, aging, and sepsis, can directly modulate protein translation initiation and muscle proteolysis, contributing to negative protein turnover. …”
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Influence of Inflammatory Cytokines IL-1β and IFNγ on Sarcoplasmic Aggregation of p62 and TDP-43 in Myotubes by Bryony McCord, Richard M. Day

“…None of the cytokine treatments affected TDP-43 protein expression, size, or frequency of TDP-43 aggregates or localization, suggesting IL-1β and IFNγ may influence TDP-43 processing in human skeletal muscle cells. TDP-43 was localized to the sarcoplasm under control conditions, suggesting this may not be a pathological feature. …”
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