Memories of a young student: the early days of splicing regulation with François Gros by Libri, Domenico

“…In particular, I was interested in how secondary structures of the RNA influence the recognition of exons specifically used in muscle cells. I will recall a few memories on how interacting with François on this project shaped my perception of the scientific process and of the relationships between models and data. …”
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Facts about Carbohydrate by Nancy J. Gal, Amanda L. Ford, Wendy J. Dahl

“…Some glucose is stored in the liver and muscle cells for later use when required. Children need carbohydrate for growth, and adults need carbohydrate to maintain their weight. …”
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Stem cells (neoblasts) and positional information jointly dominate regeneration in planarians by Xuhui Chen

“…Positional information in muscle cells governs the polarity and patterning of the body plan during homeostasis and regeneration. …”
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Paraurethral Leiomyoma in a Postmenopausal Woman: First European Case by Susy Shim, Camilla Skovvang Borg, Huda Galib Majeed, Peter Humaidan

“…Leiomyomas are benign tumors extending from smooth muscle cells and only few cases of paraurethral leiomyomas have been described in the literature. …”
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Signaling Required for Blood Vessel Maintenance: Molecular Basis and Pathological Manifestations by Masahiro Murakami

“…While signaling pathways such as VEGF, FGF, and angiopoietin-Tie2 are important for endothelial cell survival and junction stabilization, PDGF and TGF-β signaling modify mural cell (vascular smooth muscle cells and pericytes) functions, thus they fortify vessel integrity. …”
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Iatrogenic Ascending Aorta Dissection during Diagnostic Coronary Angiography: Rare but Life-Threatening by Marc Lambelin, Luc Janssens, Luc Haenen

“…A biopsy from the excised aorta showed loss of smooth muscle cells and accumulation of basophilic ground substance, clear features of cystic media necrosis. …”
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The Molecular Genetics and Cellular Mechanisms Underlying Pulmonary Arterial Hypertension by Rajiv D. Machado

“…The small pulmonary arteries of patients exhibit luminal occlusion resultant from the uncontrolled growth of endothelial and smooth muscle cells. This vascular remodelling is comprised of hallmark defects, most notably the plexiform lesion. …”
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Heparan sulphate inhibition of cell proliferation induced by TGFβ and PDGF by lan E. Silber, Jeanine M. Walenga, Jawed Fareed, Elizabeth J. Kovacs

“…The effect of glycosaminoglycans (GAGs) on the proliferation of smooth muscle cells (SMC) and fibroblasts was assessed by culturing cells with or without GAGs. …”
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Renal Replacement Therapy in Acute Kidney Failure due to Rhabdomyolysis by G. Maggi, F. Quinteros Hinojosa, M. J. Villagran, E. Guasch Arévalo, F. Gilsanz Rodríguez

“…Rhabdomyolysis is a syndrome caused by skeletal muscle cells destruction which can occur for many reasons, including prolonged immobilization. …”
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Acetylcholine in irritable bowel syndrome pathogenesis and the role of cholineblockers by Yu. O. Shulpekova

“…Experimental data allow to assume, that «subclinical inflammation» within intestinal wall at IBS, disturbances of peristaltic activity and hyperalgesia, are related to altered response of immune and smooth-muscle cells to acetylcholine stimulation.Conclusion. …”
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Is There a Metabolic Program in the Skeletal Muscle of Obese Individuals? by Joseph A. Houmard, Walter J. Pories, G. Lynis Dohm

“…These metabolic derangements are retained in human skeletal muscle cells raised in culture. Together, these findings are indicative of a dysfunctional global metabolic program with severe obesity which is of an epigenetic or genetic origin. …”
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Rationale for Antioxidant Supplementation in Sarcopenia by Francesco Cerullo, Giovanni Gambassi, Matteo Cesari

“…The molecular mechanisms leading to sarcopenia are not completely identified, but the increased oxidative damage occurring in muscle cells during the course of aging represents one of the most accepted underlying pathways. …”
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Hepatic Abnormal Secretion of Apolipoprotein C3 Promotes Inflammation in Aortic Dissection by Xinghui Zhuang, Mohammad Zarif, Yue Shen, Zhaofeng Zhang, Jian He, Linfeng Xie, Qingsong Wu, Xinfan Lin, Keyuan Chen, Yue Tian, Yong Lin, Yuling Zhang, Ziwen Cai, Zhihuang Qiu, Liangwan Chen

“…Additionally, the effect of apo C3 on the function of aortic endothelial and smooth muscle cells was explored. Apo C3 in the aortas of AD mice was found to originate from abnormal hepatic secretion, which enters the bloodstream and subsequently deposits in the aorta. …”
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The Urodele Limb Regeneration Blastema: The Cell Potential by Kenyon S. Tweedell

“…Muscle satellite reserve stem cells that are active in repair of injured muscle may also dedifferentiate and contribute new muscle cells to the limb blastema. Other cells from the dermis act as multipotent stem cells that replenish dermal fibroblasts and differentiate into cartilage. …”
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Pathophysiological and Genetic Aspects of Vascular Calcification by Luis Fernando Escobar Guzman, Cristian Andres Escobar Guzman, Neuza Helena Moreira Lopes

“…New studies point out the existence of a complex physiopathological mechanism that involves inflammation, oxidation, the release of chemical mediators, and genetic factors that promote the osteochondrogenic differentiation of vascular smooth muscle cells (VSMC). This review will evaluate the main mechanisms involved in the pathophysiology and genetics modulation of the process of vascular calcification. …”
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Insulin Resistance: A Proinflammatory State Mediated by Lipid-Induced Signaling Dysfunction and Involved in Atherosclerotic Plaque Instability by Fabrizio Montecucco, Sabine Steffens, François Mach

“…Recent studies suggest that the pathophysiology of insulin resistance is closely related to interferences with insulin-mediated intracellular signaling on skeletal muscle cells, hepatocytes, and adipocytes. Strong evidence supports the role of free fatty acids (FFAs) in promoting insulin resistance. …”
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17β-estradiol upregulates striatin protein levels via Akt pathway in human umbilical vein endothelial cells. by Shuhui Zheng, Peng Sun, Haimei Liu, Runmei Li, Lingli Long, Yuxia Xu, Suiqing Chen, Jinwen Xu

“…We previously demonstrated that E2 increases striatin levels and inhibits migration in vascular smooth muscle cells. The objective of the present study was to investigate the effects of E2 on the regulation of striatin expression in human umbilical vein endothelial cells (HUVECs). …”
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Hepatic Angiomyolipoma: A Case Report and Review of the Literature by Jekaterina Strelčenko, Justas Kuliavas, Eugenijus Stratilatovas, Audrius Dulskas

“…Hepatic angiomyolipomas are uncommon non-cancerous mesenchymal tumors that belong to the perivascular epithelioid cell tumour group. Smooth muscle cells, fat cells and blood vessels can be observed in these types of neoplasm. …”
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Endothelin but Not Angiotensin II May Mediate Hypertension-Induced Coronary Vascular Calcification in Chronic Kidney Disease by Simon W. Rabkin

“…Increased cellular phosphate may induce CAC through increased Ca x phosphate product, transformation of vascular smooth muscle cells into a bone-producing phenotype or cell apoptosis that releases procalcific substances. …”
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Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components by Laween Meran, Anna Baulies, Vivian S. W. Li

“…The cellular microenvironment including the adjacent Paneth cells, stromal cells, smooth muscle cells, and neural cells as well as the extracellular matrix together constitute the intestinal stem cell niche. …”
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