Self-reported health complaints and healthcare-seeking behaviour among adult people in rural Bangladesh: results from a cross-sectional study by Ashraful Kabir, Baki Billah, Md Nazmul Karim

“…These factors are crucial for understanding health challenges and designing effective healthcare services in rural areas.Design A cross-sectional survey was conducted from May to October 2021.Setting Four randomly selected administrative districts/regions of Bangladesh.Participants A total of 1645 rural participants aged 18 years and older.Outcome measures The study assessed the prevalence of self-reported health complaints and healthcare-seeking behaviours.Results Among the participants, 66% (1084 out of 1645) reported experiencing health complaints, with 80% seeking care and 20% either not seeking care or opting for self-care. Multivariable analysis revealed that participants with formal occupations (adjusted OR (aOR) = 0.609; 95% CI 0.396 to 0.938; p=0.025), those from the second (aOR=1.742; 95% CI 1.014 to 2.991; p=0.044) and fifth quintiles (aOR=1.210; 95% CI 0.726 to 2.019; p=0.465), with non-communicable disease (NCD) related complaints (aOR=5.299; 95% CI 3.673 to 7.643; p <0.001), and those living more than 5 km from healthcare facilities (aOR=1.725; 95% CI 1.040 to 2.861; p=0.034), were more likely to seek healthcare. …”
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Predictive value of different baseline optical coherence tomography biomarkers for visual acuity changes in neovascular age-related macular degeneration by Hamid Riazi-Esfahani, Hooshang Faghihi, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Hassan Khojasteh, Ahmed Husein Ahmed, Shahin Faghihi, Ali Fakhraie, Mohammad Hossein Zamani, Samin Ghasemi, Esmaeil Asadi Khameneh, Elias Khalili Pour

“…Baseline IRF was associated with poorer visual acuity improvement at month 12, with patients showing a mean improvement of 1.6 ± 18.2 ETDRS letters versus 11.1 ± 10 ETDRS letters in those without IRF (P = 0.002). Multivariable analysis indicated SIPED was linked to lower visual gains at month 3 (P = 0.025). …”
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DMMR status and synchronous lesions predicts metachronous lesions after curative resection for rectal cancer by Xijie Chen, Xijie Chen, Xijie Chen, Junguo Chen, Junguo Chen, Junguo Chen, Liang Xu, Liang Xu, Dezheng Lin, Dezheng Lin, Dezheng Lin, Xiaoling Hong, Xiaoling Hong, Xiaoling Hong, Junsheng Peng, Junsheng Peng, Junsheng Peng, Xiaowen He, Xiaowen He, Xiaowen He, Jiancong Hu, Jiancong Hu, Jiancong Hu

“…Univariable and multivariable analysis showed dMMR status, synchronous adenomas/polyps, surveillance time > 3, and longer surveillance period patients were significant risk factors for development of metachronous lesions; in subgroup analysis, we also found that among rectal cancer patients with synchronous adenomas, adenomas located in the left colon and rectum, and longer surveillance period were independent risk factors for detecting metachronous adenomas.ConclusionsThis study underscored the importance of extended follow-up protocols and targeted surveillance for identifying and managing metachronous lesions in dMMR rectal cancer patients, especially with synchronous adenomas. …”
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Polypharmacy and self-medication among older adults in Indian urban communities—a cross-sectional study by Saibal Das, Pavithra Gnanavel, Shalini Smanla, Anku Moni Saikia, Shilpi Mishra, Shweta Khare, S. Arun Murugan, Vadanere Nidhi Prakash, Parimita Roychoudhury, Ishteyaque Ahmad, Vishal Diwan, J. Rajesh, K. Sathish Kumar, Jugal Kishore, Namita Srivastava, Sabrina Yasmin, Mahmuda Nasrin, Rinku Borah, Mandeep Sarma Basistha, Chetanjit Baruah, Manoj Kalita, Shambo Samrat Samajdar, Jerin Jose Cherian, Ashish Pathak, Samiran Panda, Santanu Kumar Tripathi, Cecilia Stålsby Lundborg

“…Descriptive statistics, binary logistic regression, and multivariable analysis were used. The prevalence of polypharmacy was 33.7% (95% CI 29.9–37.6%), with significant associations to multiple comorbidities [adjusted odds ratio (aOR) 2.5 (95% CI 1.1–4.1)], recent transition of care [aOR 3.3 (95% CI 1.4–5.7)], and recent hospitalization [aOR 4.6 (95% CI 2–7.7)]. …”
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Comprehensive Assessment of the Risk of Symptomatic Embolism in Patients With Infective Endocarditis by Sebastian D. Santos‐Patarroyo, Juan A. Quintero‐Martinez, Brian D. Lahr, Supavit Chesdachai, Daniel C. DeSimone, Hector R. Villarraga, Hector I. Michelena, Larry M. Baddour

“…In total, 234 patients had a symptomatic embolic event, a 30‐day cumulative incidence of 30.2%. In multivariable analysis, a highly mobile vegetation was the strongest predictor of embolism (P<0.001). …”
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Serum uric acid level and subclinical left ventricular dysfunction: a community‐based cohort study by Koki Nakanishi, Masao Daimon, Yuriko Yoshida, Jumpei Ishiwata, Naoko Sawada, Megumi Hirokawa, Hidehiro Kaneko, Tomoko Nakao, Yoshiko Mizuno, Hiroyuki Morita, Marco R. Di Tullio, Shunichi Homma, Issei Komuro

“…The prevalence of abnormal LVGLS (greater than –18.6%) was greatest in the upper quartile of SUA. In multivariable analysis, SUA as a continuous variable was significantly associated with abnormal LVGLS [adjusted odds ratio (OR), 1.26 per 1 mg/dL; P = 0.008] independent of traditional cardiovascular risk factors, pertinent laboratory parameters and echocardiographic measures, and medications. …”
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Association of epidural labor analgesia with maternal and neonatal outcomes in women with preeclampsia: a propensity score-matched single-center retrospective cohort study by Xi-Zhu Wu, Tuan-Fang Fang, Yi-Han Zheng, Su-Jing Zhang, Yi Xie, Xiang Gao, Guo-Lin Lu

“…Of these, 126 (18.4%) had a higher incidence of CS in the ELA group than in the NA group (22.7% vs. 16.0%, P = 0.020). Multivariable analysis indicated greater risks of CS [adjusted Odds Ratio (aOR) = 1.71; 95% CI, 1.07–2.74; P = 0.025] and operative vaginal delivery (aOR = 2.810; 95% CI, 1.379–5.725; P = 0.004) in the ELA group than that of NA group. …”
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Surgical margins of the oral cavity: is 5 mm really necessary? by James Fowler, Yael Campanile, Andrew Warner, Francisco Laxague, Naif Fnais, Kevin Fung, Adrian Mendez, Danielle MacNeil, John Yoo, David Palma, Anthony Nichols

“…Patients with surgical margins > 1 mm experienced similar outcomes to those with margins > 5 mm. Multivariable analysis identified age of diagnosis, alcohol consumption, pathological tumour and nodal category as predictors of local recurrence free survival. …”
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Cerebral Microhemorrhages in Children With Congenital Heart Disease: Prevalence, Risk Factors, and Association With Neurodevelopmental Outcomes by Kristen N. Andersen, Sicong Yao, Brian R. White, Marin Jacobwitz, Jake Breimann, Jharna Jahnavi, Alexander Schmidt, Wesley B. Baker, Tiffany S. Ko, J. William Gaynor, Arastoo Vossough, Rui Xiao, Daniel J. Licht, Evelyn K. Shih

“…We found no significant risk factors for preoperative CMH. In multivariable analysis, neurodevelopmental duration (P<0.0001), use of extracorporeal membrane oxygenation support (P<0.0005), postoperative seizure(s) (P=0.02), and lower birth weight (P=0.03) were associated with new or worsened CMH postoperatively. …”
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Factors associated with the detection of atrial fibrillation in patients with embolic stroke of undetermined source by Jae-Han Bae, Jae-Chan Ryu, Sang Hee Ha, Min Soo Cho, Myung-Jin Cha, Jun Young Chang, Dong-Wha Kang, Sun U. Kwon, Jong S. Kim, Bum Joon Kim

“…Patients with AF had a higher prevalence of LAE, NSAT, and the imaging pattern of confluent plus additional lesions in a single vascular territory. Multivariable analysis showed that ILR implantation (hazards ratio 11.497 [95% confidence interval 3.795–34.818]), LAE (3.204 [1.096–9.370]), NSAT (4.070 [1.378–12.018]), and confluent plus additional lesions (4.977 [1.649–15.019]) were independent predictors of AF detection. …”
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A New Risk Prediction Model for the Assessment of Myocardial Injury in Elderly Patients Undergoing Non-Elective Surgery by Vedat Cicek, Mert Babaoglu, Faysal Saylik, Samet Yavuz, Ahmet Furkan Mazlum, Mahmut Salih Genc, Hatice Altinisik, Mustafa Oguz, Berke Cenktug Korucu, Mert Ilker Hayiroglu, Tufan Cinar, Ulas Bagci

“…<b>Results:</b> In total, 13% (48 out of 370 patients) of the patients developed MINS. Multivariable analysis revealed that creatinine, lymphocyte, aortic regurgitation (moderate-severe), stroke, hemoglobin, ejection fraction, and D-dimer were independent determinants of MINS. …”
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Cefazolin Alone Versus Cefazolin With Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Total Joint Arthroplasty by Meera M. Dhodapkar, MD, MHS, Scott J. Halperin, MD, MHS, Zachary Radford, MD, Lee E. Rubin, MD, FAAOS, FAOA, Jonathan N. Grauer, MD, Mengnai Li, FAAOS, MD, PhD

“…On univariable and multivariable analysis, no 90-day outcomes varied significantly. …”
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Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study by Daniela Iacono, Serena Fasano, Ilenia Pantano, Virginia D’Abrosca, Piero Ruscitti, Domenico Paolo Emanuele Margiotta, Luca Navarini, Nicola Maruotti, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Antonella Afeltra, Roberto Giacomelli, Gabriele Valentini

“…The CV event-free rate was longer in ASA-treated patients than in non-ASA-treated patients (log-rank test 12.8; p=0.0003). At multivariable analysis, arterial hypertension (HR 9.3) and hypercholesterolemia (HR 2.8) resulted to be positive predictors and ASA (HR 0.09) and hydroxychloroquine (HCQ) (HR 0.22) to be negative predictors. …”
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Clinical and microbiological analysis of risk factors for breakthrough bloodstream infection during Tigecycline Therapy by Sol Jin, So Yun Lim, Yun Woo Lee, Heungsup Sung, Mi-Na Kim, Seongman Bae, Jiwon Jung, Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Eun Hee Song, Yong Pil Chong

“…Intraabdominal (33.9%), catheter-related (30.4%), and hepatobiliary (19.1%) infections were the main sources of breakthrough BSI. In multivariable analysis, independent risk factors for breakthrough BSI during tigecycline therapy were liver cirrhosis (adjusted odds ratio [aOR], 3.09), indwelling catheter (aOR, 3.42), previous Candida colonization (aOR, 14.95), and previous multi-drug resistant bacteria colonization (aOR, 10.30). …”
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Ursodeoxycholic acid relieves clinical severity of COVID-19 in patients with chronic liver diseases by Tiantian Hu, Tiantian Hu, Jie Tong, Yunhui Yang, Changrong Yuan, Jiming Zhang, Jiming Zhang, Jiming Zhang, Jinyu Wang, Jinyu Wang

“…After performing a 1:1 age-and sex-matching, the analysis proceeded with 309 patients from each group for further evaluation.ResultsIn the UDCA-treated cohort, the incidence of asymptomatic SARS-CoV-2 infections was significantly higher, with 30.1% of patients affected, compared to 6.47% in the non-UDCA group (p &lt; 0.0001). Multivariable analysis identified UDCA as a protective factor against symptomatic infections, yielding an odds ratio (OR) of 4.77 (95% CI: 2.70–8.44, p &lt; 0.001). …”
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Changes in payer mix of new and established trauma centers: the new trauma center money grab? by Patrick Kim, Elinore Kaufman, Jeremy W Cannon, Justin Hatchimonji, Patrick M Reilly, Satvika Kumar, Diane N Haddad

“…New TCs treated more blunt trauma and less severely injured patients (p&lt;0.001). In multivariable analysis, patients presenting to new TCs were more likely to have Medicare (OR 2.0, 95% CI 1.9 to 2.1) and commercial insurance (OR 1.6, 95% CI 1.5 to 1.6) compared with Medicaid. …”
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Adjuvant chemotherapy followed by concurrent chemoradiation is associated with improved survival for resected stage I‐II pancreatic cancer by Sung Jun Ma, Gregory M. Hermann, Kavitha M. Prezzano, Lucas M. Serra, Austin J. Iovoli, Anurag K. Singh

“…Results Among 5667 patients, median follow‐up was 34.7, 45.2, and 39.7 months for the C, CRT, and C + CRT cohorts, respectively. By multivariable analysis for all patients, C and CRT had worse OS compared to C + CRT. …”
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High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor? by Stian Magnus Staurung Orlien, Tekabe Abdosh Ahmed, Nejib Yusuf Ismael, Nega Berhe, Trine Lauritzen, Svein Gunnar Gundersen, Asgeir Johannessen

“…ANA was excluded from multivariable analysis since there was no seropositive in the reference group. …”
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Local Recurrence of Rectal Cancer After Transanal Total Mesorectal Excision and Risk Factors: A Nationwide Multicenter Cohort Study in Japan by Takeru Matsuda, MD, PhD, Ichiro Takemasa, MD, PhD, Hideki Endo, MD, MPH, Shinichiro Mori, MD, PhD, Suguru Hasegawa, MD, PhD, Koya Hida, MD, PhD, Takuya Tokunaga, MD, PhD, Keitaro Tanaka, MD, PhD, Toshiki Mukai, MD, PhD, Jun Watanabe, MD, PhD, Junichiro Kawamura, MD, PhD, Kei Kimura, MD, PhD, Yoshihiro Kakeji, MD, PhD, Masahiko Watanabe, MD, PhD, Seiichiro Yamamoto, MD, PhD, Takeshi Naitoh, MD, PhD, Ta-Ta-Mi study group collaboratives in Japan Society of Laparoscopic Colorectal Surgery

“…Tumor height from the anal verge, pathological T4 disease, pathological stage III/IV, positive perineural invasion, and R1 resection were significant risk factors for LR in multivariable analysis. Conclusions:. In this selected cohort in which intersphincteric resection or abdominoperineal resection was performed in more than half of cases, oncological outcomes were acceptable during a median follow-up of more than 3 years.…”
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Clinical Utility of a Structured Program to Reduce the Risk of Health-Related Quality of Life Impairment after Discharge from Intensive Care Unit: A Real-World Experience by Angelica Venni, Francesca Ioia, Silvia Laviola, Francesca Frigieri, Alessandra Pieri, Simona Marilli, Daniela Balzi, Piercarlo Ballo, Stefano Gori, Diletta Guarducci

“…Similar good results were found by the questionnaire of memories. In multivariable analysis, no variable was found to predict the risk of PICS in our population. …”
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