Comparison of clinicopathological characteristics and prognosis between primary squamous cell carcinoma of the thyroid and squamous cell carcinoma combined with papillary thyroid c... by Wanyun Yan, Huiying Chen, Xiaoyu Lin, Ruifa Zhou, Feng Zhao, Jiping Su

“…The prognostic factors were different between the two groups. Multivariable analysis shows that the N stage, M stage, radiotherapy, and tracheal invasion were related to the prognosis of PSCCT, while only the T stage was associated with the prognosis in SCC-PTC.ConclusionsClinicopathological characteristics and prognosis were not identical in patients with SCC-PTC and PSCCT. …”
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The Utility of Point of Care Test for Soluble ST2 in Predicting Adverse Cardiac Events during Acute Care of ST-Segment Elevation Myocardial Infarction by Anggoro Budi Hartopo, Indah Sukmasari, Ira Puspitawati

“…Among subjects with STEMI, the supramedian group had higher incidence of adverse cardiac events than the inframedian group (38.3% versus 12.5%, p=0.004). Multivariable analysis showed that supramedian sST2 level was independently associated with increased incidence of adverse cardiac events (adjusted OR 6.27; 95% CI: 1.33–29.47, p=0.020). …”
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Prevalence and predictors of confirmed infection in patients receiving empiric antimicrobials in the intensive care unit: a retrospective cohort study by Luis Carlos Maia Cardozo Júnior, Larissa Bianchini, Jakeline Neves Giovanetti, Luiz Marcelo Almeida de Araújo, Yuri de Albuquerque Pessoa dos Santos, Bruno Adler Maccagnan Pinheiro Besen, Marcelo Park

“…Primary outcome was infection status, defined as confirmed, probable, possible, or discarded. In a multivariable analysis, we explored variables associated with confirmed infection. …”
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Effect of preoperative right ventricular dysfunction and dilatation on survival after left ventricular surgical restoration by Abdelhameed Elsayed, Murtadha H. Alawami, Ismail M. Elnaggar, Tamer N. Mohamed, Musab Kiddo, Mostafa A. Shalaby, Khaled A. Alotaibi, Amr A. Arafat

“…Long-term follow-up revealed no significant reduction in RV diameter after surgery. Multivariable analysis revealed that EuroSCORE II [HR, 1.05; P < 0.01], atrial fibrillation [HR, 3.34; P < 0.01], left ventricular longitudinal diameter [HR, 0.97; P < 0.01], and right ventricular basal diameter [HR, 1.06, P < 0.01] were independent predictors of long-term mortality. …”
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Clinical implications of proximal tubular multicilia in glomerular diseases by Bohye Kim, Boram Weon, Evonne Kim, Sohee Park, Wencheng Jin, Nayeon Shin, Yun Kyu Oh, Chun Soo Lim, Jung Pyo Lee, Obin Kwon, Jeonghwan Lee

“…Patients with higher MCC ratios had a significantly higher risk of end-stage kidney disease (ESKD) and composite outcomes with death. In multivariable analysis, MCC ratios were significantly correlated with an increased risk of ESKD (hazard ratio [HR], 1.413; 95 % confidence interval [CI], 1.012–1.972) and composite outcome (HR, 1.401; 95 % CI, 1.028–1.909). …”
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Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect by Swetha Reddi, Liliia Senyshyn, Maryam Ebadi, Daniel Podlesny, Samuel S. Minot, Ted Gooley, Amanda J. Kabage, Geoffrey R. Hill, Stephanie J. Lee, Alexander Khoruts, Armin Rashidi

“…Donor 3 yielded a median engraftment rate of 66%, higher than donors 1 (P = 0.02) and 2 (P = 0.03) in multivariable analysis. Three patients developed severe aGVHD; all 3 had received FMT from donor 1. …”
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Association of Serum Melatonin Level with Mild Cognitive Impairment in Type 2 Diabetic Patients: A Cross-Sectional Study by Jichen Zhang, Jiancan Lu, Hongling Zhu, Xinglu Zhou, Xijuan Wei, Mingjun Gu

“…Melatonin level was negatively correlated with age (r = −0.202; P = 0.001), diabetes duration (r = −0.282; P < 0.001), serum HbA1c (r = −0.195; P = 0.002), hs-CRP (r = −0.324; P < 0.001), and TSH (r = −0.184; P = 0.004) levels and positively correlated with MoCA score, serum HDL-C (r = 0.145; P < 0.001), FT3 (r = 0.241; P < 0.001), and FT4 (r = 0.169; P = 0.008) levels. The multivariable analysis indicated that fewer years of formal education, longer diabetes duration, higher serum HbA1c, higher serum hs-CRP, and lower serum melatonin are the predisposing factors for MCI. …”
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Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation by Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Toshio Horiuchi, Takahiko Omameuda, Kiichiro Takadra, Ryosuke Akimoto, Yasuharu Onishi, Yasunaru Sakuma, Koichi Mizuta

“…We collected information on the occurrence and timing of episodes of CMV infections, methylprednisolone (mPSL) pulse therapy, patient characteristics, and peri- and postoperative data. Results Multivariable analysis identified mPSL pulse therapy (Odds Ratio (OR): 4.43), CMV serostatus (D+/R−) (OR: 6.03), and underlying IMDs (OR: 3.28) as independent risk factors for CMV infection. …”
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Total Psoas Area Predicts Complications following Radical Cystectomy by Timothy D. Lyon, Nicholas J. Farber, Leo C. Chen, Thomas W. Fuller, Benjamin J. Davies, Jeffrey R. Gingrich, Ronald L. Hrebinko, Jodi K. Maranchie, Jennifer M. Taylor, Tatum V. Tarin

“…TPA was significantly lower for patients who experienced any complication (7.8 cm2/m2 versus 8.8 cm2/m2, P=0.023) and an infectious complication (7.0 cm2/m2 versus 8.7 cm2/m2, P=0.032) than those who did not. On multivariable analysis, TPA (adjusted OR 0.70 (95% CI 0.56–0.89), P=0.003) and Charlson comorbidity index (adjusted OR 1.34 (95% CI 1.01–1.79), P=0.045) were independently associated with 90-day complications. …”
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FAN score predicts prognosis after platinum-based first-line chemotherapy in patients with metastatic urothelial carcinoma by Yu Ishizuya, Atsunari Kawashima, Yuki Horibe, Akinaru Yamamoto, Masaru Tani, Akihiro Yoshimura, Liu Yutong, Sassi Nesrine, Toshiki Oka, Yohei Okuda, Toshihiro Uemura, Gaku Yamamichi, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Norio Nonomura

“…The median PFS and overall survival (OS) were 6.3 months (95% confidence interval [CI] 4.5–8.0) and 14.0 months (95% CI 11.1–16.9), respectively. Multivariable analysis showed that Fib-4 index (HR 3.85, 95% CI 1.09–13.58, p = 0.036), ALBI score (HR 1.53, 95% CI 1.01–2.31, p = 0.045), and NLR (HR 1.76, 95% CI 1.14–2.71, p = 0.010) were independently associated with PFS. …”
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Oral Hygiene Practices and Associated Factors among Patients Visiting Private Dental Clinics at Hawassa City, Southern Ethiopia, 2018 by Desalegn Humna Beyene, Bereket Beyene Shashamo, Lankamo Ena Digesa, Eshetu Zerihun Tariku

“…Crude and adjusted OR with 95% confidence level was estimated, and variables having P value ≤0.05 in multivariable analysis were considered as significant. Results. 393 study participants participated making a response rate of 97.52%. …”
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Risk Factors for Rebleeding after Emergency Endoscopic Treatment of Dieulafoy Lesion by Yongkang Lai, Jianfang Rong, Zhenhua Zhu, Wangdi Liao, Bimin Li, Yin Zhu, Youxiang Chen, Xu Shu

“…In the univariable analysis, endoscopic treatment, prothrombin time, gender, Rockall score, and leukocyte count were the risk factors for rebleeding. In the multivariable analysis, pure injection endoscopic treatment, white blood cells (>10 × 109/L), and prothrombin time >12 seconds were the independent risk factors for rebleeding. …”
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Magnitude and Determinants of Antenatal Care Utilization in Kandahar City, Afghanistan by Muhammad Haroon Stanikzai, Mohammad Hashim Wafa, Abdul Wahed Wasiq, Hadia Sayam

“…Factors that remained significantly associated with antenatal care services’ utilization in multivariable analysis included women’s educational status (adjusted odds ratio (AOR) = 2.0, 95% CI: 1.0–4.3), pregnancy intention (AOR = 2.1, 95% CI: 1.1–3.4), and place of residence (AOR = 1.7, 95% CI: 1.1–2.6). …”
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New-onset Diabetes Mellitus among adults as sequelae of COVID-19 in selected tertiary care hospital, Puducherry – A cohort study by Venkatachalam Jayaseelan, Sitanshu Sekhar Kar, Mahadevan Duraiswamy, Manju Rajaram, Vikas Menon, Mukta Wyawahare, D.R. Veda Priya, Ravivarman Lakshmanasamy, Vanessa Ravel, Renjana Sivaji

“…Results: Among the study participants, the relative risk of developing Diabetes Mellitus was 2.83 (95 % CI: 1.98–4.06) for the exposed group (moderate/severe cases) compared to the comparison group (mild/asymptomatic). Multivariable analysis further confirmed a relative risk of 2.01 (95 % CI: 1.26–3.20, p = 0.003) for moderate/severe COVID-19 cases, with significant associations for age, smoking, and comorbidities. …”
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Serum Galectin-3 Predicts Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients by Jianlong Zhu, Dehui Guo, Liying Liu, Jing Zhong

“…Compared with the nonsurvivors, survivors had lower acute physiology and chronic health evaluation (APACHE) II scores (p < 0.001), increased left ventricular ejection fraction (p < 0.05), lower Gal-3 levels at 24 and 72 h (both p = 0.001), lower BNP levels at 24 and 72 h (both p = 0.001), and higher platelet counts (p = 0.009). Further multivariable analysis showed that APACHE II score, BNP-T72, and Gal-3-T72 were independent risk factors for death in VA-ECMO patients. …”
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Prevalence and Clinical Characteristics including Patterns of Antihypertensive Drug Administration of the Different Home Blood Pressure Phenotypes in Treated Hypertensive Patients by Chavalit Chotruangnapa, Tossaporn Thammarux, Piyawan Thongdang

“…Classical BP control status was 35.21% well-controlled hypertension, 30.01% white-coat uncontrolled hypertension, 9.74% masked uncontrolled hypertension, and 25.04% sustained uncontrolled hypertension. The multivariable analysis showed the significantly associated factor of MoHT was the presence of previous cardiovascular disease (adjusted OR 5.54, 95% CI (2.02–15.22); p value = 0.001). …”
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Prevalence and Correlates of Hypertension Unawareness among Lebanese Adults: The Need to Target Those “Left Behind” by Fatima Ghaddar, Lama Hammad, Rania A. Tohme, Tamar Kabakian-Khasholian, Nahla Hwalla, Abla M. Sibai

“…A total of 369 subjects were unaware of their condition, representing 51.8% of all hypertensives and 15.9% of the apparently healthy. Multivariable analysis controlling for a number of confounders showed that, among apparently healthy participants, insurance coverage and contact with healthcare services were not associated with higher likelihood for hypertension awareness. …”
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Undernutrition and Associated Factors among Lactating Women: Community-Based Cross-Sectional Study in Moyale District, Borena Zone, Southern Ethiopia by Hailu Bekele, Gebi Husein Jima, Ashenafi Habtamu Regesu

“…Descriptive statistics like frequency, mean, and percentage were computed to describe characteristics of the sample. Multivariable analysis was carried out, association between independent and dependent variables were measured using adjusted odds ratios, and its 95% confidence interval and P value below 0.05 were considered statistically significant. …”
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Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning by Shuxian Pan, Zibing Wang

“…The impact of influencing factors on irAEs (immune-related adverse events) was validated using Decision Curve Analysis (DCA). Both uni/multivariable analysis were accomplished by Chi-square/Fisher’s exact tests. …”
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RESILSTIGMA. Resilience to self-stigmatization experienced by people living with HIV: Which self-reported factors improve awareness among health workers? by Christine Jacomet, Cécile Miele, Emilie Goncalves, Céline Lambert, Clément Belletier, Françoise Linard, Josiane Phalip-Le Besnerais, Pierre Dellamonica, Michaël Dambrun

“…A total of 279 PLHIV (42%) reported items of self-stigmatization. Multivariable analysis showed that self-stigmatization was significantly associated with major depression (OR: 3.59, 95% CI: 1.19 to 10.80, p = 0.02), psychological inflexibility (OR: 1.53, 95% CI: 1.19 to 1.97, p = 0.001), and parental support deficit in childhood (OR parental support: 0.63, 95% CI: 0.40 to 0.98, p = 0.04). …”
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