Delirium at the intensive care unit and long-term survival: a retrospective study by Ignazio De Trizio, Maria Angeliki Komninou, Jutta Ernst, Reto Schüpbach, Jan Bartussek, Giovanna Brandi

“…Overall, patients in the group D had a significantly lower probability of survival than patients in the group ND (p < 0.0001, ARD = 11.8%). In the multivariable analysis, ICU-delirium was confirmed as independently associated with long-term survival. …”
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Non-cancerous CT findings as predictors of survival outcome in advanced non-small cell lung cancer patients treated with first-generation EGFR-TKIs. by Pakorn Prakaikietikul, Pattraporn Tajarenmuang, Phumiphat Losuriya, Natee Ina, Thanika Ketpueak, Thanat Kanthawang

“…MPA size, MPA size > 29 mm, and total adiposity ≤85 cm2 remained significant in multivariable analysis, adjusted by BMI [HR 1.14 (1.07-1.21), p < 0.001; 3.10 (1.81-5.28), p < 0.001; 3.91 (1.63-9.40), p = 0.002]. …”
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Identifying key signs of motor neurone disease in primary care: a nested case–control study using the QResearch database by Aleksandar Radunović, Carol Coupland, Julia Hippisley-Cox, Christopher J McDermott, Tom A Ranger, Judith Burchardt, Xue W Mei

“…The nested case–control data set comprised of 6437 cases of MND diagnosed between January 1998 and December 2019, matched by year of birth, gender, general practice and calendar year to 62 003 controls.Main outcome measures Clinically recognised symptoms and signs of MND prior to diagnosis and symptoms and factors which are relevant in primary care setting.Results This study identified 17 signs and symptoms that were independently associated with MND diagnosis in a multivariable analysis. Of these, seven were new to the Red Flag tool: ataxia, dysphasia, weight loss, wheeze, hoarseness of voice, urinary incontinence and constipation. …”
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Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dyna... by Yuhui Guo, Chengsi Li, Haichuan Guo, Peiyuan Wang, Xuebin Zhang

“…Results A total of 1430 patients were included in model development, with 41 cases (2.87%) of superficial SSI and 6 cases (0.42%) of deep SSI. Multivariable analysis identified traditional prognostic factors older age (OR = 1.08, 95% CI 1.04–1.12), ASA class III-IV (OR = 2.46, 95% CI 1.32–4.56), surgical delay ≥ 6 days (OR = 3.59, 95% CI 1.36–9.47), surgical duration > 180 min (OR = 2.72, 95% CI 1.17–6.35), and systemic inflammation biomarkers Platelet-to-lymphocyte ratio (PAR) ≥ 6.6 (OR = 2.25, 95% CI 1.17–4.33) and Systemic Immune-Inflammation Index (SII) ≥ 541.1 (OR = 2.24, 95% CI 1.14–4.40) as independent predictors of SSI. …”
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Practice of balanced scorecard implementation and its contributing factors among public primary hospital professionals in Central Gondar zone, Northwest Ethiopia by Seid Yeshaw, Seid Yeshaw, Geta Asrade, Asebe Hagos, Muluken Genetu Chanie, Nigusu Worku

“…The strength of associations was measured using the adjusted odds ratio (AOR) at 95% CI and a p-value of less than 0.05 in the multivariable analysis to declare significant factors. Thematic analysis was applied for the qualitative data using open code 4.03 version software.ResultsThe implementation practice of BSC was found at 48.5% (95% CI: 43.6, 53.4%) with a response rate of 95.28%. …”
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Discharge against Medical Advice (DAMA) from an Emergency Department of a Tertiary Care Hospital in Saudi Arabia by Ashraf El-Metwally, Nesreen Suliman Alwallan, Ali Amin Alnajjar, Nida Zahid, Khalid Alahmary, Paivi Toivola

“…The prevalence of DAMA in our study was 1%. In a multivariable analysis, after adjusting for the other covariates, we observed a significant interaction between age and gender. …”
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Left Ventricular End-Systolic Volume Is a Reliable Predictor of New-Onset Heart Failure with Preserved Left Ventricular Ejection Fraction by Marina Kato, Shuichi Kitada, Yu Kawada, Kosuke Nakasuka, Shohei Kikuchi, Yoshihiro Seo, Nobuyuki Ohte

“…A correlation analysis revealed that LVESVI was significantly associated with log BNP level (r = 0.356, p<0.001), +dP/dt (r = −0.324, p<0.001), −dP/dt (r = 0.391, p<0.001), and tau (r = 0.337, p<0.001). Multivariable analysis with a stepwise procedure using the variables with statistical significance in the univariable analysis revealed that aging, an increase in BNP level, and enlargement of LVESVI were significant prognostic indicators (age: HR: 1.071, 95% CI: 1.009–1.137, p=0.024; log BNP : HR : 1.533, 95% CI: 1.090–2.156, p=0.014; LVESVI : HR : 1.051, 95% CI: 1.011–1.093, p=0.013, respectively). …”
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Right ventricular–pulmonary artery coupling in cardiac resynchronization therapy: evolution and prognosis by Jan Stassen, Xavier Galloo, Kensuke Hirasawa, Surenjav Chimed, Nina Ajmone Marsan, Victoria Delgado, Pieter van derBijl, Jeroen J. Bax

“…Survival rates at 3 and 5 year follow‐up were significantly lower for patients with a TAPSE/PASP ratio <0.45 mm/mmHg (76% and 58%, respectively), compared with those with a TAPSE/PASP ratio ≥0.45 mm/mmHg (91% and 82%, respectively) (P < 0.001). On multivariable analysis, TAPSE/PASP ratio <0.45 mm/mmHg (hazard ratio 1.437; 95% confidence interval: 1.145–1.805; P = 0.002) was independently associated with all‐cause mortality, whereas TAPSE <17 mm (hazard ratio 1.237; 95% confidence interval: 0.990–1.546; P = 0.061) was not. …”
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Low transthyretin is associated with the poor prognosis of colorectal cancer by Zhe Zhang, Zhe Zhang, Zhe Zhang, Chenhao Hu, Chenhao Hu, Chenhao Hu, Feiyu Shi, Feiyu Shi, Feiyu Shi, Lei Zhang, Lei Zhang, Lei Zhang, Ya Wang, Ya Wang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Junjun She, Junjun She, Junjun She

“…Comparative analysis revealed that the TTR-higher group exhibited a younger demographic, a higher prevalence of low colorectal cancers, an elevated R0 resection rate, superior differentiation, earlier stage and lower levels of carcinoembryonic antigen (CEA) in contrast to the TTR-lower group. The Cox multivariable analysis underscored the significance of TTR and various clinicopathological factors, encompassing age, tumor location, R0 resection status, differentiation grade, disease stage, postoperative chemoradiotherapy, and preoperative CEA levels, as substantial prognostic indicators. …”
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Parasitic infection prevalence in tuberculosis patients and their household contacts in the Littoral Region of Cameroon by Lucy Cho Nchang, Chefor Magha, Patience Agwa Fonong, Narcisse Victor Tchamatchoua Gandjui, Nancielle Mbiatong Tchatat, Desmond Akumtoh Nkimbeng, Frank Noel Nietcho, Juluis Visnel Foyet, Fanny Fri Fombad, Tatiana Djikeussi Katcho, Jerome Fru Cho, Achim Hoerauf, Manuel Ritter, Samuel Wanji

“…Descriptive analysis was performed, bivariate analysis was computed and a multivariable analysis was done to provide adjusted odds ratios (AOR). …”
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A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score by Xi Liu, Yiran Hu, Wei Hua, Shengwen Yang, Min Gu, Hong-Xia Niu, Li-Gang Ding, Jing Wang, Shu Zhang

“…Among 387 patients, 109 (28.2%) met super-response. In multivariable analysis, 5 independent predictors (QQ-LAE) were identified: prior no fragmented QRS (odds ratio (OR) = 3.10 (1.39, 6.94)), QRS duration ≥170 ms (OR = 2.37 (1.35, 4.12)), left bundle branch block (OR = 2.57 (1.04, 6.37)), left atrial diameter <45 mm (OR = 3.27 (1.81, 5.89)), and left ventricular end-diastolic dimension <75 mm (OR = 4.11 (1.99, 8.48)). …”
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Diffuseness of coronary artery disease impacts on immediate hemodynamic and predicted clinical outcomes by Shigetaka Kageyama, Pruthvi Chenniganahosahalli Revaiah, Tsai Tsung-Ying, Kotaro Miyashita, Akihiro Tobe, Neil O’Leary, Johan H. C. Reiber, Shengxian Tu, Azfar Zaman, Manel Sabaté, Helge Möllmann, Faisal Sharif, Julien Lemoine, Adrian Wlodarczak, Scot Garg, Yoshinobu Onuma, Patrick W. Serruys

“…A “Predominantly diffuse” pattern with a major gradient had a higher risk of a post-PCI QFR < 0.91 (OR 1.52,95%CI 1.47–1.58). In multivariable analysis, low QFR PPG index (diffuse disease) was an independent determinant of a post-PCI QFR < 0.91 (per 0.1 decrease of QFR PPG index, OR:9.8, 95% CI 3.0–32.2, p < 0.001). …”
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The association of physical activity and carotid intima-media-thickness in adolescents—data of the prospective early vascular ageing-tyrol cohort study by Bernhard Winder, Bernhard Winder, Bernhard Winder, Sophia J. Kiechl, Sophia J. Kiechl, Benoît Bernar, Benoît Bernar, Nina Gande, Anna Staudt, Anna K. Stock, Anna K. Stock, Christoph Hochmayr, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Stefan Kiechl, Ursula Kiechl-Kohlendorfer, Michael Knoflach, Michael Knoflach, the Early Vascular Ageing (EVA)-Tyrol Study Group, Carmen Reiter, Christina Schreiner Julia Klingenschmid, Julia Marxer, Martina Kothmayer, Maximilian Pircher, Manuela Bock-Bartl, Mandy Asare, Maximilian Bohl, Raimund Pechlaner

“…PA was rated by an in-person interview on the basis of average minutes of moderate- or vigorous sports per day and by the Baecke questionnaire expressed as Baecke score (BS).ResultsComplete data set was available for 1,001 adolescents with a mean age of 17.8 years (standard deviation ±0.9 years). 558 (55.7%) of participants were female. cIMT was positively associated with both measures of PA in univariate (minutes sports per day: p &lt; 0.001; BS: p &lt; 0.001) as well as multivariable analysis adjusting for established cardiovascular risk factors (minutes sports per day: p = 0.001; BS: p = 0.002). …”
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Age‐related longitudinal change in cardiac structure and function in adults at increased cardiovascular risk by Fei Fei Gong, Jennifer M. Coller, Michele McGrady, Umberto Boffa, Louise Shiel, Danny Liew, Simon Stewart, Alice J. Owen, Henry Krum, Christopher M. Reid, David L. Prior, Duncan J. Campbell

“…Age was associated with longitudinal increase in left ventricular (LV) mass index (LVMI); decrease in LV volumes; increase in LV ejection fraction; decrease in mitral annular systolic velocity; decrease in diastolic function (decreased mitral early diastolic annular velocity (e′); and increase in left atrial volume index, mitral peak early diastolic flow velocity (E)/e′ ratio, and tricuspid regurgitant velocity (TRVmax) in men and women, except for TRVmax in men). In multivariable analysis, longitudinal increase in LVMI was explained by CVD risk factors alone, whereas age, together with CVD risk factors, independently predicted longitudinal change in all other echocardiographic parameters. …”
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Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest by Hao-Wei Lee, Ming-Jen Kuo, Pai-Feng Hsu, I-Hsin Lee, Chih-Yu Yang, Teh-Fu Hsu, Chorng-Kuang How, Yenn-Jiang Lin, Chin-Chou Huang

“…Among patients without ESRD, 82.5% developed AKI, of which 31.0% achieved AKI recovery, while 61.0% were discharged with impaired renal function. Multivariable analysis using regression models revealed that unfavorable neurological outcomes at discharge and higher mortality at 2 years were associated with AKI (odds ratio [OR] 7.684, 95% confidence interval (CI) 2.683–22.010, P < 0.001; hazard ratio [HR] 2.159, 95% CI 1.272–3.664, P = 0.004), AKI without recovery (OR 5.275, 95% CI 2.049–13.583, P < 0.001; HR 5.470, 95% CI 3.304–9.862, P < 0.001), and impaired pre-discharge renal function (OR 3.164, 95% CI 1.442–6.940, P = 0.004; HR 2.876, 95% CI 1.861–4.443, P < 0.001). …”
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Prognosis of nodal micrometastasis in resectable pN0 non-small cell lung cancer by Sophon Siwachat, Sophon Siwachat, Sophon Siwachat, Apichat Tantraworasin, Apichat Tantraworasin, Apichat Tantraworasin, Nirush Lertprasertsuke, Somcharoen Saeteng, Somcharoen Saeteng

“…Among pN0 patients, nodal micrometastasis was found in 21 cases (21.43%), distributed as follows: 2 (2.04%) in hilar and interlobar regions (N1), 17 (17.35%) in the mediastinal region (N2), and 2 in both hilar and mediastinal regions (N1+N2) (2.04%).Univariable analysis revealed that male sex and the presence of tumor necrosis increased both the recurrence rate of lung cancer and the mortality rate, whereas larger tumor size, intra-tumoral vascular invasion, and pleural invasion were associated solely with cancer recurrence. However, multivariable analysis showed no statistically significant difference in disease-free survival and overall survival between pN0 patients with and without NMM, with hazard ratios of 0.98 (95% CI: 0.31-3.08, P=0.973) and 1.11 (95% CI: 0.23-5.42, P=0.900), respectively.ConclusionNodal micrometastasis was identified in 21.43% of pN0 resectable NSCLC patients. …”
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Abnormal Liver Tests during Hospitalization Predict Mortality in Patients with COVID-19: A Multicenter Study from South America by Domingo Balderramo, Angelo Z. Mattos, Victoria Mulqui, Talita Chiesa, Zuly Plácido-Damián, Jaysoom Abarca, Andrea Bolomo, Yanina Carlino, Isadora Z. Bombassaro, Denusa Wiltgen, Laura Tenorio Castillo, Karina Díaz, Johana Acuña, Estela Manero, Jhon Prieto, Enrique Carrera, Javier Díaz-Ferrer, Jose D. Debes

“…Patients were followed until hospital discharge or death. Multivariable analysis was used to evaluate the association between ALEx2 on admission and during hospitalization and mortality. …”
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Poor sleep quality and associated factors among HIV-positive and negative postpartum women in Addis Ababa, Ethiopia: a comparative cross-sectional study by Milen Mihertabe, Alehegn Bishaw Geremew, Alehegn Bishaw Geremew, Elsa Awoke Fentie, Gidey Rtbey

“…Variables having a p-value of less than 0.05 in multivariable analysis were considered statistically significant and an adjusted odds ratio with a 95% confidence interval (CI) was computed.ResultsIn this study, the overall prevalence of poor sleep quality among postpartum women was 56.3% [95% CI (51.9, 60.6)]. …”
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Suicidal ideation and suicide attempt among pregnant adolescent girls in Ghana: a cross-sectional study by Kwaku Oppong Asante, Emmanuel Nii-Boye Quarshie, Erica Danfrekua Dickson, Sandra Naa-Shasha Quarshie, Sophia Ewuenye Adwoa Kpebu

“…We applied bivariable and multivariable analysis techniques to the data.Results Overall, 28.51% (95% confidence interval (CI) 24.37% to 32.93%) reported suicidal ideation, and 18.04% (95% CI 14.59% to 21.91%) reported suicide attempt during the current pregnancy. …”
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Delays in health care seeking for diarrheal disease and associated factors among caregivers of under five children in health centers of northwest Ethiopia: a mixed-method study by Asnakech Marew, Zenebe Jebero Zaza, Shiferaw Birhanu, Amare Belachew, Tsehaynew Kasse

“…Variables with a p- value < 0.05 in the multivariable analysis were considered to be significantly associated. …”
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