Faktor Yang Mempengaruhi Kepatuhan Berobat Pasien Yang Diterapi Dengan Tamoxifen Setelah Operasi Kanker Payudara by Arif Budiman, Daan Khambri, Hafni Bachtiar

“…Of the 61 patients we found 9 patients not adherent tamoxifen therapy, the results bivariant a significant association between adherence to the age, level of education, familyIncome, availability of health insurance and medical care (p<0.05). Multivariate analysis found that the most influential factor is the care of medical personnel with p=0.06. …”
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Evaluation of Inflammatory, Cardiac and Hematological Parameters in Hospitalized Children with COVID-19 by Damla Geçkalan, Rahmi Özdemir, Zülal Yılmaz, Onur Sivas, Yasin Yılmaz, Cemile Hilal Çelik

“…There was a statistically significant difference in the length of hospitalization, age, white blood cell and troponin values between the patients with COVID-19 pneumonia and those without pneumonia (p<0.001, p=0.008, p=0.048, and p=0.003, respectively). When multivariate analysis was performed for these parameters, the probability of pneumonia was found to be 1.17 times higher for every additional year of age. …”
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Revisiting ABC Transporters and Their Clinical Significance in Glioblastoma by Brandon Wee Siang Phon, Shalini Sundramurthi Chelliah, Dina El-Rabie Osman, Saatheeyavaane Bhuvanendran, Ammu Kutty Radhakrishnan, Muhamad Noor Alfarizal Kamarudin

“…Using the datasets in The Cancer Genome Atlas and Gene Expression Omnibus, we found upregulated ABC transporters that either negatively impacted survival in univariate analyses (ABCA1, ABCA13, ABCB9, ABCD4) or were independent negative prognosis factors for patients with GBM (ABCA13, ABCB9). Our multivariate analysis further demonstrated three ABC transporters, ABCA13 (Hazard Ratio (HR) = 1.31, <i>p</i> = 0.017), ABCB9 (HR = 1.26, <i>p</i> = 0.03), and ABCB5 (HR = 0.77, <i>p</i> = 0.016), with the administration of alkylating agents (HR = 0.41, <i>p</i> < 0.001), were independent negative prognosis factors for patients with GBM. …”
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Does binge drinking between the age of 18 and 25 years predict alcohol dependence in adulthood? A retrospective case–control study in France by Marie-Pierre Tavolacci, Joel Ladner, Pierre Déchelotte, Quentin Berthon, Damiano Cerasuolo, Alexandre Baguet

“…Frequent binge drinking between 18 and 25 years occurred in 75.9% of cases and 41.0% of controls (p&lt;0.0001). After multivariate analysis, frequent binge drinking between 18 and 25 years was a risk factor for alcohol dependence between 25 and 45 years: adjusted OR=2.83, 95% CI 1.10 to 7.25.Conclusions Frequent binge drinking between 18 and 25 years appears to be a risk factor for alcohol dependence in adulthood. …”
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Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease by Adilia Mirela Pereira Lima Cid, Davi de Sá Cavalcante, Marcela Lima Gurgel, Ana Carolina Saraiva, Ana Alicia Sales Ricardo, Lúcio Mitsuo Kurita, Paulo Goberlânio de Barros Silva, Catarina Brasil d’Alva, Ana Rosa Pinto Quidute, Fabio Wildson Gurgel Costa

“…In the PHPT group, low BMD was linked to an increased average TBSP length (p = 0.025) and a higher frequency of elongated TBSP (p = 0.022). Multivariate analysis revealed an inverse relationship between the T-score of the femoral neck and TBSP length in the PHPT group (p = 0.028). …”
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Prognostic Impact of miR-224 and RAS Mutations in Medullary Thyroid Carcinoma by Elisabetta Cavedon, Susi Barollo, Loris Bertazza, Gianmaria Pennelli, Francesca Galuppini, Sara Watutantrige-Fernando, Simona Censi, Maurizio Iacobone, Clara Benna, Federica Vianello, Stefania Zovato, Davide Nacamulli, Caterina Mian

“…Patients whose MTCs had a low miR-224 expression tended to have a shorter overall survival (log-rank test p=0.005). On multivariate analysis, miR-224 represented an independent prognostic marker. …”
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Development and validation of a nomogram for predicting cough variant asthma diagnosis by Jiao Min, Xiaomiao Tang, Di Zhang, Jin Yang, Fei Li, Wei Lei

“…Results Of the 241 outpatients, 156 (64.7%) were diagnosed with CVA. Multivariate analysis identified several independent predictors of CVA, including cough triggered by cold air (OR = 12.493, P = 0.019), exposure to pungent odors (OR = 3.969, P = 0.002), cough phasing (OR = 4.515, P < 0.001), history of allergic rhinitis (OR = 3.231, P = 0.018), and the percentage of the predicted value of maximum mid-expiratory flow (MMEF%pred) (OR = 0.981, P = 0.039) were independent predictors of CVA. …”
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A Circulating Subpopulation of Monocytic Myeloid-Derived Suppressor Cells as an Independent Prognostic/Predictive Factor in Untreated Non-Small Lung Cancer Patients by Eleni-Kyriaki Vetsika, Filippos Koinis, Marianthi Gioulbasani, Despoina Aggouraki, Anna Koutoulaki, Eirini Skalidaki, Dimitris Mavroudis, Vassilis Georgoulias, Athanasios Kotsakis

“…Increased percentages of monocytic-MDSCs were associated with worse response to treatment (P=0.02) and patients with normal levels of CD14+CD15+CD11b+CD33+HLA-DR−Lin− had longer overall survival and progression free-survival compared to those with high levels (P=0.008 and P=0.005, resp.). Multivariate analysis revealed that the increased percentages of CD14+CD15+CD11b+CD33+HLA-DR−Lin− MDSCs were independently associated with decreased progression free-survival and overall survival. …”
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Prevalence, correlates of postpartum depression during the COVID-19 pandemic; and validation of the arabic edinburgh postnatal depression scale among Lebanese women by Christian El Kahwaji, Elie Barakat, Feten Fekih-Romdhane, Camille Akkari, Savio Barakat, Souheil Hallit

“…A total of 239 women (59.5%) had potential postpartum depression. Multivariate analysis showed that perceived childbirth experience (as “normal” (Beta= -2.57), “good” (Beta= -3.45) and “very good” (Beta= -4.14)), with worries that the newborn will get hurt/die during labor (“rarely” (Beta = 1.43) and “never” (Beta = 1.24)), a lower financial burden (Beta = − 0.19) and a higher social support (Beta = − 0.02) were significantly associated with lower rates of PPD; while higher levels of anxiety (Beta = 0.32) were associated with increased symptoms of PPD. …”
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Correlates of Calcaneal Quantitative Ultrasound Parameters in Patients with Diabetes: The Study on the Assessment of Determinants of Muscle and Bone Strength Abnormalities in Diabe... by Francesco Conti, Stefano Balducci, Luca Pugliese, Valeria D’Errico, Martina Vitale, Elena Alessi, Gerardo Salerno, Carla Iacobini, Stefano Menini, Lucilla Bollanti, Antonio Nicolucci, Giuseppe Pugliese

“…Among surrogate measures of complications, sensory and motor nerve amplitude and heart rate response to cough test and standing correlated with QUS parameters at univariate analysis, together with age, body mass index (BMI), waist circumference, lipid profile, and renal function. Multivariate analysis revealed that BUA, SOS, QUI, and BMD were independently associated with age, male gender, hemoglobin A1c, BMI (or fat, but not fat-free mass), and somatic and autonomic nerve function parameters. …”
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Postoperative Morbidity and Mortality of Perforated Peptic Ulcer: Retrospective Cohort Study of Risk Factors among Black Africans in Côte d’Ivoire by Soro Kountele Gona, Mahassadi Kouamé Alassan, Koffi Gnangoran Marcellin, Kissi Ya Henriette, Coulibaly Adama, Assohoun Toussaint, Ehua Adjoba Manuela, Seu Gagon Sylvain, Afum-Adjei Awuah Anthony, Ehua Somian Francis

“…Follow-up results were the incidence of complications and mortality of 6.4 (95% CI: 4.9–8.0) per 100 person-days and 3.0 (95% CI: 1.9–4.0) per 100 person-days for incidence of mortality. In multivariate analysis, risk factors of postoperative complications or mortality were comorbidities (HR = 2.1, P=0.03), tachycardia (pulse rate > 100/minutes) (HR = 2.4, P=0.02), purulent intra-abdominal fluid collection (HR = 2.1, P=0.04), hyponatremia (median value ≤ 134 mEq/L) (HR = 2.3, P=0.01), delayed time of hospital admission > 72 hours (HR = 2.6, P<0.0001), and delayed time of surgical intervention between 24 and 48 hours (HR = 3.8, P<0.0001). …”
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Arterial Thromboembolism in Patients With Advanced Lung Cancer: Secondary Analyses of the Rising‐VTE/NEJ037 Study by Naoki Furuya, Yukari Tsubata, Takamasa Hotta, Toshihide Yokoyama, Masahiro Yamasaki, Nobuhisa Ishikawa, Kazunori Fujitaka, Tetsuya Kubota, Kunihiko Kobayashi, Takeshi Isobe

“…The most common location for ATE was cerebral infarction (N = 31, 75.6%), followed by myocardial infarction (N = 4, 9.8%). Multivariate analysis determined the incidence of VTE, D‐dimer, a comorbidity of atrial fibrillation, and four other factors as independent risk factors of ATE. …”
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Value of C-Reactive Protein in Predicting Left Ventricular Remodelling in Patients with a First ST-Segment Elevation Myocardial Infarction by Iwona Swiatkiewicz, Marek Kozinski, Przemyslaw Magielski, Tomasz Fabiszak, Adam Sukiennik, Eliano Pio Navarese, Grazyna Odrowaz-Sypniewska, Jacek Kubica

“…The prevalence of LVR was higher in patients from the highest quartile of CRP concentrations at 24 h as compared to those from any other quartile (odds ratio (OR) 3.48, 95% confidence interval (95% CI) 1.76–6.88). Multivariate analysis identified CRP concentration at 24 h (OR for a 10 mg/L increase 1.29, 95% CI 1.04–1.60), B-type natriuretic peptide at discharge (OR for a 100 pg/mL increase 1.21, 95% CI 1.05–1.39), body mass index (OR for a 1 kg/m2 increase 1.10, 95% CI 1.01–1.21), and left ventricular end-diastolic volume (OR for a 1 mL increase 0.98, 95% CI 0.96-0.99) as independent predictors of LVR. …”
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Low expression of TOX predicts poor prognosis of patients with breast cancer in the real world: A retrospective study by Chunlei Tan, Danping Wu, Xiaotian Yang, Shiyuan Zhang, Shuqiang Liu, Boqian Yu, Xiao Yu, Yuting Xiu, Yuanxi Huang

“…Based on Cox regression analyses, multivariate analysis indicated that TOX was the potential prognostic factor for both DFS (HR: 0.412, 95 % CI: 0.248–0.684, P = 0.001) and OS (HR: 0.395, 95 % CI: 0.237–0.660, P < 0.0001). …”
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Efficacy and safety of FOLFIRI/aflibercept in second‐line treatment of metastatic colorectal cancer in a real‐world population: Prognostic and predictive markers by Ana Fernández Montes, Nieves Martínez Lago, Marta Covela Rúa, Juan de la Cámara Gómez, Paula González Villaroel, José Carlos Méndez Méndez, Mónica Jorge Fernández, Mercedes Salgado Fernández, Margarita Reboredo López, Guillermo Quintero Aldana, María Luz Pellón Augusto, Begoña Graña Suárez, Jesús García Gómez

“…Development of hypertension (any grade) was significantly associated with a reduced risk of progression by multivariate analysis (HR = 2.7; 95%CI 1.3‐5.4; P = 0.001). …”
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Analisis Karakteristik Keluarga dan Pemanfaatan Posyandu Lansia terhadap Psychological Well Being Lansia di Kecamatan IV Angkek Kabupaten Agam Tahun 2014 by Rosmery ., Rizanda Machmud, Kuswardani Susari Putri

“…The result of psychological well-being level showed high 78,7% and 21,3% was low and there was connected between family education level of activities community service, sports events and religious activities. On multivariate analysis gets Ekp 7,785 in the utilization of health services, health service means 7,785 times greater than effect elderly psychological well-being.The conclution of this variabel have effect to psychologicall well-being in Kecamatan IV Angkek Kabupaten Agam. …”
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Surgical Outcomes and Clinicopathological Characteristics of Patients Who Underwent Potentially Noncurative Endoscopic Resection for Gastric Cancer: A Report of a Single-Center Exp... by Hiroaki Ito, Haruhiro Inoue, Haruo Ikeda, Noriko Odaka, Akira Yoshida, Hitoshi Satodate, Manabu Onimaru, Daisuke Takayanagi, Esperanza Grace Santi, Shin-ei Kudo

“…Fisher's exact test was used for univariate analysis. For multivariate analysis, stepwise multiple linear regression was used to identify independent predictors related to lymph node metastasis and remnant of primary tumor. …”
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Prognostic Value of the Red Blood Cell Distribution Width-to-Albumin Ratio in Critically Ill Older Patients with Acute Kidney Injury: A Retrospective Database Study by Lei Guo, Dezhun Chen, Bihuan Cheng, Yuqiang Gong, Benji Wang

“…After controlling for ethnicity, gender, age, and other confounding variables in multivariate analysis, higher RA was significantly associated with an increased risk of 30-day, 90-day, and one-year all-cause mortality as opposed to the reduced levels of RA (tertile 3 vs. tertile 1: hazard ratios (HRs), 95% confidence intervals (CIs): 1.70, 1.43–2.01; 1.90, 1.64–2.19; and 1.95, 1.72–2.20, respectively). …”
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The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions by Xuegang Li, Haijian Jiang, Xu Wang, Shuping Zhong

“…However, only sclerostin had correlation with the CBM scores in multivariate analysis (ρ = -0.040, p < 0.001). Conclusions In the r-axSpA patients with fatty lesions, serum sclerostin levels are declined. …”
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Role of postoperative radiotherapy in pT3N0 rectal cancer: A risk‐stratification system based on population analyses by Yun‐xia Huang, Yan‐zong Lin, Jin‐luan Li, Xue‐qing Zhang, Li‐rui Tang, Qing‐yang Zhuang, Fei‐fei Lin, Xi‐jin Lin, Jun‐xin Wu

“…The overall 5‐year CSS was 86.31%. Multivariate analysis showed that age (P < 0.001), tumor differentiation (P = 0.044), number of nodes resected (P = 0.032), marital status (P = 0.005), and radiotherapy (P = 0.006) were independent prognostic factors for CSS. …”
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