Absence of Standard Modifiable Risk Factors in Middle Eastern Patients with Atherosclerotic Cardiovascular Disease. The Jordan Absence of Standard Modifiable Risk Factors (SMuRF-Le... by Hammoudeh AJ, Aldalal’ah M, Smadi EA, Alrishoud D, Alomari A, Alkhawaldeh M, Rizik A, Okour MF, Araydah M

“…One year survival in the SMuRF-less patients was significantly lower than that in the SMuRFs groups (97.7% vs.98.4% vs.98.3%, respectively, p = 0.01). Multivariate analysis showed that young age, absence of heart failure and utilization of secondary preventive medications were associated with better one year outcome.Conclusion: In this cohort of ME patients with ASCVD, nearly four in 100 were SMuRF-less. …”
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Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small... by Ratna Nurhayati, Aulia Rizka, Cleopas Martin Rumende, Noorwati Sutandyo, Arif Hanafi, Edy Rizal Wahyudi, Hamzah Shatri, Anna Mira Lubis, Em Yunir, Muhammad Firdaus, Yuniar Harris Prayitno, Nadira Nibras Taqiyya

“…Statistical analyses were performed using SPSS 20.0, employing the log-rank method for bivariate analysis and Cox regression for multivariate analysis. Results: In a cohort of 108 patients, the majority were aged 60–69 years (74.1 %), male (66.7 %), diagnosed at stage IV (80.5 %), and with adenocarcinoma subtype (75.0 %). …”
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Clinical characteristics and outcomes of surgical resection for brain metastases from lung adenocarcinoma by Ming Li, Zhiying Li, Hang Zhang, Hiroaki Wakimoto, Linlin Sun, Tiantian Wang, Shengli Zhou, Liyun Zhou

“…The median survival time was 11.5 months, and the 3-year survival rate was 15.7%. Multivariate analysis revealed that smoking history, Ki67 percentage, KPS after craniotomy, and molecular targeted therapy after craniotomy were independent factors affecting the survival time of patients.ConclusionsAlthough survival remains poor, patients who had no-smoking history, Ki67 percentage ≤30%, KPS≥80 after craniotomy, and molecular targeted therapy after craniotomy can improve the prognosis and prolong the survival time.…”
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Direct collaboration between hospitals and NGOs, an essential tool to reinforce linkage to care in people living with HIV by Teresa Aldámiz-Echevarria, Chiara Fanciulli, Mónica Lopez, Leire Perez, Francisco Tejerina, David Sanchez, Blanca Lodeiros, Juan Carlos López, Juan Berenguer, Jose Maria Bellon, Maria Ferris, Mario Blazquez, Almudena Calvo, Mario Domene, Oswaldo Vegas, Carmen Rodriguez, Patricia Muñoz, Paloma Gijon, Pedro Montilla, Elena Bermudez, Maricela Valerio, Roberto Alonso, Belen Padilla, Critina Ventimilla, Cristina Diez

“…Most of them hadn´t healthcare coverage (78%). In multivariate analysis, that included all PLHIV seen for the first time in the ID Unit between 2019 and 2022, lack of healthcare coverage was the only independent predictor of lost to FU that reached statistical significance (HR 5.19, CI 2.76–9.47). …”
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Impact of Preoperative and Intraoperative Factors on Postoperative Outcomes in Patients with Colorectal Cancer: A 10-Year Retrospective Study by Lucian Flavius Herlo, Ioana Golu, Alexandra Herlo, Claudia Raluca Balasa Virzob, Ionescu Alin, Stela Iurciuc, Ionut Eduard Iordache, Luana Alexandrescu, Doina Ecaterina Tofolean, Raluca Dumache

“…Intraoperative factors such as blood loss greater than 500 mL (<i>p</i> < 0.001) and longer operative time (<i>p</i> = 0.021) were also significant predictors of adverse outcomes. Multivariate analysis identified elevated CRP (OR 2.1, 95% CI 1.5–2.9), low albumin (OR 1.8, 95% CI 1.3–2.5), and blood loss > 500 mL (OR 2.4, 95% CI 1.7–3.4) as independent predictors of postoperative complications. …”
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Serum hsa-miR-22-3p, hsa-miR-885-5p, Lipase-to-Amylase Ratio, C-Reactive Protein, CA19-9, and Neutrophil-to-Lymphocyte Ratio as Prognostic Factors in Advanced Pancreatic Ductal Ade... by Jakub Wnuk, Dorota Hudy, Joanna Katarzyna Strzelczyk, Łukasz Michalecki, Kamil Dybek, Iwona Gisterek-Grocholska

“…Utility as prognostic biomarkers was confirmed in univariate and multivariate analysis for CA19-9, CRP, and NLR. The selected miRNAs and LAR were not confirmed as reliable prognostic markers in PC.…”
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Risk factors for new vertebral fractures after percutaneous vertebroplasty or percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fractures by Wencheng Yang, Kaiwei Zou, Xuping Lin, Yanfang Yang, Tianpei Chen, Xiuming Wu, Xiaomeng Wang, Qingjun Liu, Chunhui Huang, Wanhan Su

“…Differential analysis revealed that age, diabetes, hemoglobin (HB), total protein (TP), serum albumin (ALB), b-C-terminal telopeptide of type I collage (β-CTX), 25-hydroxyvitamin D (25-OH-D3), number of fractured vertebrae, bone mineral density (BMD), regular exercise after discharge, anti-osteoporosis treatment after discharge, cross-sectional area (CSA), and fatty degeneration ratio (FDR) were associated with new vertebral fractures (all P &lt; 0.05). Multivariate analysis showed that age (OR = 1.519, P = 0.032), diabetes (OR = 3.273, P = 0.048), and FDR (OR = 1.571, P = 0.027) were positively associated with the occurrence of new vertebral fractures, while bone mineral density (OR = 0.108, P = 0.044), 25-OH-D3 (OR = 0.871, P = 0.032), CSA (OR = 0.564, P = 0.009), regular postoperative exercise (OR = 0.259, P = 0.025), and osteoporosis treatment (OR = 0.291, P = 0.045) were negatively associated with the occurrence of new vertebral fractures.ConclusionPatients with osteoporosis fractures who are older, have poor glycemic control, lower bone mineral density, lower levels of 25-OH-D3, weaker paraspinal muscles, and higher fat infiltration are at increased risk of new vertebral fractures after undergoing PKP/PVP. …”
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Pulmonary aspergillosis in US Veterans with COVID-19: a nationwide, retrospective cohort study by Kaitlin Swinnerton, Nathanael R. Fillmore, Ikwo Oboho, Janet Grubber, Mary Brophy, Nhan V Do, Paul A Monach, Westyn Branch-Elliman

“…The 90-day mortality among aspergillosis cases was 50%. In the multivariate analysis, immune suppression (aOR 6.47, CI 3.84–10.92), chronic respiratory disease (aOR 3.57, CI 2.10–6.14), and age >70 (aOR 2.78, CI 1.64–4.80) were associated with aspergillosis. …”
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Prediction Models of Severity in Acute Biliary Pancreatitis by Iulia Ratiu, Renata Bende, Camelia Nica, Oana Budii, Calin Burciu, Andreea Barbulescu, Tudor Moga, Bogdan Miutescu, Roxana Sirli, Mirela Danila, Alina Popescu, Felix Bende

“…In univariate analysis, the following parameterswere associatedwith at least a moderate–severe form of acute pancreatitis: Balthazar score, fasting blood glucose (mg/dL), modified CTSI score, CRP values at 48 h, BISAP score at admission, CTSI score, Ranson score, duration of hospitalization (days), and the presence of leukocytosis (×1000/µL) (all <i>p</i> < 0.05).BISAP score at admission (AUC-0.91), CRP levels at 48 h (AUC-0.92), mCTSI (AUC-0.94), and CTSI score (AUC-0.93) had the highest area under the curve (AUC) for predicting the severity of acute pancreatitis. In multivariate analysis, the model including the following independent parameters was predictive for the severity of acute pancreatitis: CTSI score (<i>p</i> < 0.0001), BISAP score (<i>p</i> = 0.0082), and CRP levels at 48 h (<i>p</i> = 0.0091), respectively. …”
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Rainy and Dry Seasons Are Relevant Factors Affecting Chemical and Antioxidant Properties of Meliponini Honey by Flavia C. Lavinas, Brendo A. Gomes, Marcos V. T. Silva, Raissa Lima, Suzana G. Leitão, Mirian R. L. Moura, Rosineide C. Simas, Renata F. Barbosa, Fabricio O. Silva, Carla S. Carneiro, Igor A. Rodrigues

“…The mineral composition, particularly potassium, phosphorus, and calcium, remained stable. Multivariate analysis identified <i>m</i>/<i>z</i> ions (VIP scores > 2.5), rather than physicochemical or antioxidant capacity parameters, as critical for seasonal discrimination. …”
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SUMO-Specific Peptidase 5 Promotes Oesophageal Squamous Cell Carcinoma Growth through the NF-κB-SLC1A3 Axis by Chaoxiang Du, Yunfan Hu, Xinyu Yang, Zhe Zhang, Jianmin Gu, Tao Zhang, Renfeng Wang, Shaoyuan Zhang, Lijie Tan, Guiping Yu

“…The Kaplan‒Meier method and multivariate analysis were used to analyse the relationship between SENP5 expression and ESCC prognosis. …”
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Evaluation of Inflammatory Markers and Clinical Outcomes in COVID-19 Patients with Concurrent <i>Clostridioides difficile</i> Infection: A Comparative Cohort Analysis by Flavia Ignuta, Adrian Vlad, Teodor Cerbulescu, Stana Loredana, Felix Bratosin, Ovidiu Rosca, Lavinia Stelea, Daciana Nistor

“…Inflammatory indices correlated strongly with disease severity: elevated CAR and low PNI were associated with higher odds of ICU admission and mortality (<i>p</i> < 0.001). Multivariate analysis identified co-infection status, increased IL-6, and elevated CAR as independent predictors of severe outcomes. …”
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Analysis of cervical and breast cancer screening behavior and its influencing factors among urban and rural women in Beijing. by Yanqing Gao, Guoxin Liang, Chun Chang, Feng Pan, Fumin Huang, Litong Gong, Liyu Huang

“…The rate of cervical cancer screening behavior increased with increasing education level and family per capita monthly income, and the highest percentage of respondents had a college education or above (PCervical cancer screening = 35.2%, PBreast cancer screening = 23.6%, PAt least one = 38.2%, PBoth cancers were screened = 20.6%), as did the percentage of families whose per capita monthly income was above 15, 000 yuan (PCervical cancer screening = 34.7%, PBreast cancer screening = 27.3%, PAt least one = 38.3%, PBoth cancers were screened = 23.6%). Multivariate analysis revealed that an age range of 45 to 59 years (PAll four screening conditions were obtained<0.001), an education level of junior high school, a high school (PAll four screening conditions were obtained<0.001), a college education or above (PAll four screening conditions were obtained<0.001), a marital status of a spouse (PAll four screening conditions were obtained<0.001), a divorce status (PAll four screening conditions were obtained<0.001) or a widowhood status (PAll four screening conditions were obtained<0.001), and a medical insurance status (PAll four screening conditions were obtained<0.001) were positively correlated with the percentages of the four screening behaviors.…”
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E_N_T_R_O_P_Y: Monocentric analysis of rectal cancer radio-chemotherapy treatment in patients of young age by E. Meldolesi, A. Nicolì, N. Dinapoli, G. Chiloiro, A. Romano, R. Menghi, R. Persiani, F. Pacelli, C. Coco, C. Ratto, S. Manfrida, L. Boldrini, B. Corvari, M.A. Gambacorta

“…In patients over 55 years old, there was a clear dominance of the advanced risk class (62 % of the total). In multivariate analysis, OS and DFS decrease with increasing age and ESMO risk group. …”
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Variations in the diagnostic performance of transurethral resection of bladder tumor with photodynamic diagnosis according to surgical experience: A retrospective, single-center st... by Shuhei Suzuki, Yoshiyuki Nagumo, Kosuke Kojo, Atsushi Ikeda, Bunpei Isoda, Akane Yamaguchi, Kozaburo Tanuma, Satoshi Nitta, Masanobu Shiga, Takashi Kawahara, Shuya Kandori, Akio Hoshi, Hiromitsu Negoro, Bryan J. Mathis, Hiroyuki Nishiyama

“…In addition, the accuracy rate was also significantly lower in tangential effect areas (59.6 % vs. 80.8 %). Multivariate analysis identified urological experience as a significant factor improving accuracy rate (odds ratio [OR] 2.14) while tangential effects substantially reduced accuracy rate (OR 0.37). …”
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Determinants of infants and young children feeding practices among mothers living in Saudi Arabia: a cross-sectional study by Fatimah Alsada, Tunny Sebastian, Zainab Alzayer, Hawraa Alabbas, Narjis Alhaddad, Hawraa Abu Shahin, Atheer Alghamdi, Haya F. Alhmly, Malek J. Baassiri, Bedour Alkhalifa, Antonina N. Mutoro, Wesam A. Alyahya

“…The rate of breastfeeding within the first hour, and exclusively breastfeeding for six months was both 25%. Multivariate analysis showed that exclusive breastfeeding for at least six months was less likely in middle-income mothers were less likely to exclusively breastfeed for six months than high-income mothers (OR = 0.32; 95% CI: 0.18–0.57; p < 0.001). …”
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Real-world outcomes of maintenance therapy post-autologous stem cell transplantation in newly diagnosed multiple myeloma by Ka-Won Kang, Dae Sik Kim, Se Ryeon Lee, Mi Hwa Heo, Hyeon-Seok Eom, Jongheon Jung, Ji Hyun Lee, Sung-Hyun Kim, Youngil Koh, Chang-Ki Min, Seung Shin Lee, Sung-Nam Lim, Ho-Young Yhim, Myung-won Lee, Je-Jung Lee, Sung-Hoon Jung, Soo-Mee Bang, Kihyun Kim, the Korean Multiple Myeloma Working party [KMMWP]

“…The median progression-free survival (PFS) from the time of ASCT was 26.4 and 44.1 months in the no-maintenance and maintenance groups, respectively. In the multivariate analysis, the use of maintenance therapy was significantly associated with better PFS. …”
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Metabolic Modulation and Potential Biomarkers of the Prognosis Identification for Severe Aortic Stenosis after TAVR by a Metabolomics Study by Yanbiao Liao, Chang Liu, Tianyuan Xiong, Mingyue Zhao, Wen Zheng, Yuan Feng, Yijian Li, Yuanweixiang Ou, Zhengang Zhao, Yong Peng, Jiafu Wei, Qiao Li, Wei Meng, Xiaojing Liu, Mao Chen

“…Influential metabolites were identified by integrating the univariate test, multivariate analysis, and weighted gene coexpression network analysis (WGCNA) algorithm. …”
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Predictive factors of fibrotic interstitial lung abnormality on high-resolution computed tomography scans: a prospective observational study by Kazuya Ichikado, Hidenori Ichiyasu, Kazuhiro Iyonaga, Kodai Kawamura, Yuko Yasuda, Keisuke Anan, Hiroko Okabayashi, Kimitaka Akaike, Noritaka Higashi, Takeshi Johkoh, Kiminori Fujimoto, Tetsuo Saito, Jun Morinaga, Minoru Yoshida, Katsuhiko Mitsuzaki, Takuro Sakagami

“…Results Fibrotic interstitial lung abnormalities were observed on high-resolution computed tomography scans in 135 (82%) patients at the time of diagnosis. Multivariate analysis showed that older age (Odds ratio, 1.06; 95% confidence interval, 1.01–1.12; p = 0.021), auscultatory fine crackles (Odds ratio, 3.39; 95% confidence interval, 1.33–8.65; p < 0.01), and elevated serum surfactant protein-D (Odds ratio, 2.68; 95% confidence interval, 1.02–8.64; p = 0.045) were independent predictive factors of fibrotic interstitial lung abnormalities. …”
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Factors associated with failure of humerus nonunion surgery in patients with initial nonoperative management by Alexander Hysong, MD, Noah Harrison, MD, Samuel Posey, MD, Ziqing Yu, MS, Andrew T. Chen, MD, Patrick Pallitto, MD, Joseph R. Hsu, MD, William Obremskey, MD, Evidence-Based Musculoskeletal Injury and Trauma Collaborative (EMIT), Hassan Mir, MD, Roman M. Natoli, MD, PhD, Ishani Sharma, MD, MBA, Jenna Jones, Med, Luke A. Lopas, MD, Hassan Farooq, MD, Robert D. Zura, MD, Alexander Padovano, MD, Nathaniel Koutlas, MD, Steve Hemmerly, BS, Elsa Rodriguez, MD, Daniel E. Pereira, MD, Sharon Babcock, MD, Gabriel James Sowards, BS, Martha Holden, AAS, AA, Anna N. Miller, MD, Marc Schatz, MD, Jessica Rivera, MD, PhD, Katrina Bang, MD, Kamryn King, BS, Zachery Hong, BA, Jarrod Dumpe, MD, Gabriella Lea Stribling, BS, Merritt John Thompson, MD, Tracy Johns, MSN, RN-BC, Rachel Seymour, PhD, Susan Odum, PhD, Stephen Sims, MD, Olivia Rice, MD, Ainsley Bloomer, MD, Katheryn Peterson, BSPH, Amber Stanley, BSPH, Mario Cuadra, MD, Gisele Bailey, MS, Matthew Braswell, MD, Landon Bulloch, MD, William Haynes, MD, Josef Jolissaint, MD, Julia Mastracci, MD, Andrew Wohler, MD, Eddie Komie Afetse, BS, BA, Cara Girardi, Juliette Sweeney, BS, Benjamin Averkamp, MD, Meghan Wally, PhD, Madhav Karunakar, MD, Kevin Phelps, MD, Laurence Kempton, MD, Christine Churchill, MA, CCRP, David Macknet, MD, Hannah Pollock, BS, Rodney Arthur, MS, Samuel Cohen-Tanugi, Isaac Boateng, James Michael Ruth, BS, Joseph Michalski, MD, Anna Hemminger, BS, Kathryn Leighty, Mir Ibrahim Sajid, MD, Thea Lance, BA, William Hunter Waddell, MD, Andres Fidel Moreno Diaz, MD, Joseph Gutbrod, BS, Christopher G. Herbosa, BS

“…Moreover, 34 patients (31.48%) experienced 1 or more postoperative complications. Multivariate analysis found that the use of bone graft or bone graft substitute was not associated with successful nonunion surgery (95% odds ratio confidence interval [CI] [0.67–5.3], P = 0.23). …”
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