Arterial Stiffness Is More Associated with Albuminuria than Decreased Glomerular Filtration Rate in Patients with Type 2 Diabetes Mellitus: The REBOUND Study by Jong Ho Kim, Sang Soo Kim, In Joo Kim, Bo Hyun Kim, Ja Young Park, Chang Won Lee, Ji Hye Suk, Sun Hae Shin, Sung Pyo Son, Min Chul Kim, Jun Hyeob Ahn, Kwang Jae Lee, Min Jung Kwon, Soon Hee Lee, Jeong Hyun Park

“…A univariate analysis revealed that maximal baPWV was significantly associated with both the ACR (r=0.297, P<0.001) and eGFR (r=−0.220, P<0.001). A multivariate analysis adjusted for significant clinical variables and eGFR showed that baPWV remained significantly correlated with the ACR (r=0.150, P<0.001). …”
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Prevalence and Determinants of Peripheral Neuropathy among Type 2 Adult Diabetes Patients Attending Jimma University Medical Center, Southwest Ethiopia, 2019, an Institutional-Base... by Daba Abdissa, Nigusse Hamba, Kumsa Kene, Deriba Abera Bedane, Guluma Etana, Dassalegn Muleta, Asfaw Gerbi

“…A variable having a p value of < 0.25 in the bivariate model was subjected to multivariate analysis to avoid confounding variable’s effect. …”
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Incidence and predictors of seizure-related injuries among epileptic patients undergoing follow-up treatment at public hospitals in Central Ethiopia by Selamawit Wondale Begizew, Bethelhem Birhanu Muluneh, Taye Mezgebu Ashine, Asnakech Zekiwos Heliso, Getachew Ossabo Babore, Elias Ezo Ereta, Sentayehu Admasu Saliya, Awoke Girma Hailu, Elias Nigusu Abdisa

“…The incidence density rate of seizure-related injuries among epileptic patients was 11.97 per 100 person-months of observation (95% CI 10.61, 13.50). In multivariate analysis, epileptic patients who had generalized tonic–clonic seizures (adjusted hazard ratio 1.4, 95% CI 1.07–1.84), comorbidities (adjusted hazard ratio 1.3, 95% CI 1.11–1.71), were on polytherapy drug regimens (adjusted hazard ratio 1.80, 95% CI 0.30–2.49), and consumed alcoholic drinks (adjusted hazard ratio 1.5, 95% CI 1.21–1.89) were identified as independent predictors of seizure-related injuries. …”
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Outcomes of Idecabtagene Vicleucel Therapy in Patients with Relapsed/Refractory Multiple Myeloma: A Single-Institution Experience by Aaron Trando, Farid Ghamsari, Philip Yeung, Caitlin Costello, Ila Saunders, Ah-Reum Jeong

“…Univariate and multivariate analysis revealed no significant predictors of ORR, PFS, or OS. …”
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Incidence, prevalence, and predictors of osteoporotic fracture in adult lung transplant recipients by Elisabeth Ng, Shanal Kumar, Eldho Paul, Daniel Bennett, Luisa Rosi, Louise Fuller, Lauren Chiu, Shoshana Sztal-Mazer, Steven Ivulich, Greg Snell, Leon A. Bach, Kathryn L. Hackman

“…Antiresorptive therapy was received by 47% pre- and 89% post-LT. On multivariate analysis, risk factors for osteoporotic fracture were pre-LT osteoporotic fracture (hazard ratio (HR) 2.32 (95% confidence interval (CI) 1.09-4.96)), female sex (HR 2.08 (95% CI 1.09-3.94)), glucocorticoid use pre-LT (HR 2.08 (95% CI 1.09-3.99)), and time (months) to first ZA infusion post-LT (HR 1.04 (95% CI 1.01-1.06)). …”
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Evolution of Treatment Outcomes and Prognostic Factors in Esophageal Cancer Surgery: A Retrospective Analysis of 1500 Consecutive Esophagostomies by Yasue Kimura, MD, PhD, Eiji Oki, MD, PhD, Tomonori Nakanoko, MD, PhD, Qingjiang Hu, MD, PhD, Keita Natsugoe, MD, Sho Nanbara, MD, PhD, Ryota Nakanishi, MD, PhD, Yuichiro Nakashima, MD, PhD, Mitsuhiko Ota, MD, PhD, Tomoharu Yoshizumi, MD, PhD

“…The prognosis improved over time. Multivariate analysis revealed that depth of invasion, lymph node metastasis, the extent of lymph node resection, curative resection, pulmonary complications, and anastomotic leakage were significant independent prognostic factors. …”
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Liver Transplantation without Perioperative Transfusions Single-Center Experience Showing Better Early Outcome and Shorter Hospital Stay by Nicolás Goldaracena, Patricio Méndez, Emilio Quiñonez, Gustavo Devetach, Lucio Koo, Carlos Jeanes, Margarita Anders, Federico Orozco, Pablo D. Comignani, Ricardo C. Mastai, Lucas McCormack

“…While median MELD was significantly higher in Yes-Transfusion (11 versus 21; P=0.0001) group, platelet count, prothrombin time, and hemoglobin were significantly lower. On multivariate analysis, the unique independent risk factor associated with P-RBC transfusions was preoperative hemoglobin (P<0.001). …”
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Knowledge of prevention and treatment of infectious diarrhea among parents of children under five with diarrhea in Anhui province: an outpatient-clinic-based questionnaire survey by Yuanfang SUN, Yongkang XIAO, Lei GONG, Hongyuan WEI, Wanwan MA, Shuo FENG, Qiang ZHANG, Linlin LI, Qile WU, Jiabing WU

“…A self-developed questionnaire was used in the survey, which included the parental demographic information, general awareness of infectious diarrhea, and knowledge of infectious diarrhea prevention (10 questions with one point for each correct answer and a total score of 8 was defined as knowledge of the disease prevention) and treatment. A multivariate analysis of factors influencing parental knowledge of diarrhea prevention was performed using binary logistic regression, adjusting for potential confounders. …”
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Minimal disease activity and associated factors in patients with psoriatic arthritis: cross-sectional study from a single center by Murat Bektas, Berk Çelik, Burak İnce, Yasemin Yalçınkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç

“…In univariate analysis, MDA was associated with higher patient age, longer psoriasis duration, late-onset PsA, and continued use of first TNFi. In multivariate analysis, higher patient age, late-onset PsA, and higher continuation rate of first TNFi were associated with MDA. …”
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Prevalence of Diabetes and Associated Risk Factors among a Group of Prisoners in the Yaoundé Central Prison by Sylvain Raoul Simeni Njonnou, Jérôme Boombhi, Martine Claude Etoa Etoga, Aimée Tiodoung Timnou, Ahmadou Musa Jingi, Kevin Nkem Efon, Esther Astrid Mbono Samba Eloumba, Marie-Josiane Ntsama Essomba, Odette Kengni Kebiwo, Alice Ninon Tsitsol Meke, Stéphane Talbit Ndjonya, Mesmin Dehayem Yefou, Eugène Sobngwi

“…Hypertension (p=0.005), obesity (p=0.0006), smoking (p=0.04), sedentary lifestyle (p=0.04), major crime (p=0.007), and minor crime (p=0.003) were associated with diabetes in univariate analysis. In multivariate analysis, only obesity and sedentary lifestyle were associated with diabetes. …”
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A Randomized Trial of Ionic Silver Dressing to Reduce Surgical Site Infection After Gastrointestinal Surgery by Chihiro Kosugi, MD, Keiji Koda, MD, Hiroaki Shimizu, MD, Masato Yamazaki, MD, Kiyohiko Shuto, MD, Mikito Mori, MD, Akihiro Usui, MD, Hiroyuki Nojima, MD, Satoshi Endo, MD, Hiroo Yanagibashi, MD, Hidehito Arimitsu, MD, Toru Tochigi, MD, Tetsutaro Sazuka, MD, Mihono Hirota, MD, Hideyuki Kuboki, MD

“…There was no significant difference in superficial SSI rates between the groups in patients undergoing upper gastrointestinal surgery; however, the rate was significantly lower in the study group in patients undergoing lower gastrointestinal surgery (P = 0.042). Multivariate analysis identified Aquacel Ag Hydrofiber dressings as an independent factor for reducing superficial SSIs (odds ratio, 0.602; 95% confidence interval, 0.367–0.986; P = 0.044). …”
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Impact of Helicobacter pylori infection on neoadjuvant chemotherapy in locally advanced gastric cancer: a retrospective analysis by Bin Zhong, Zhizhong Xiong, Jiabo Zheng, Saddam Ahmed Mohamed, Jiachen Sun, Dayin Huang, Zijian Deng, Jianping Guo, Junsheng Peng, Huashe Wang, Lei Lian

“…Further analysis revealed that H. pylori infection was significantly associated with the major pathological response (P = 0.009). Multivariate analysis showed that factors related to major pathological response included; age ≤ 50 (OR: 0.423, 95% CI: 0.194–0.925), H. pylori infection (OR: 0.396, 95% CI: 0.183–0.854), pathological stage T 3/4 (OR: 0.524, 95% CI: 0.288–0.954), and CA12-5 > 35 U/mL (OR: 0.345, 95% CI: 0.132–0.904). …”
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The Clinical Characteristics, Patterns of Recurrence, and Long-Term Survival Outcomes of Dual-Phenotype Hepatocellular Carcinoma After Curative Liver Resection by Yu ZC, Fang ZK, Yu Y, Liu SY, Wang KD, Shi ZJ, Jin LM, Huang XK, Lu Y, Shen GL, Liu JW, Huang DS, Zhang CW, Liang L

“…Meanwhile, among patients with tumor recurrence after surgery, patients with DPHCC have a higher proportion of advanced-stage tumors, and extrahepatic metastasis (all P < 0.05). Moreover, multivariate analysis showed that DPHCC is an independent risk factor for both OS (HR 1.399, 95% CI 1.061– 1.845, P = 0.017) and RFS (HR 1.313, 95% CI 1.033– 1.669, P = 0.026).Conclusion: DPHCC, an aggressive HCC subtype with poor differentiation and high invasiveness, shows inferior RFS and OS post-liver resection compared to CHCC. …”
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Acute Infusion-Related Side Effects of Amphotericin B Lipid Complex (ABLC) in Oncohematological Patients: Real-World Data from Brazilian Reference Centers by Francelise Bridi Cavassin, Marcello Mihailenko Chaves Magri, Ariela Victoria Borgmann, Isabela Dombeck Floriani, Marina Rachid Barreto, Tania Zaleski, Fabianne Altruda de Moraes Costa Carlesse, Giovanni Luís Breda, Fábio de Araújo Motta, Diego Rodrigues Falci, Ana Verena Almeida Mendes, Hugo Paz Morales, Patrícia Silva Montes, Mariane Taborda, Talita Teles Teixeira Pereira, João Luiz Baú-Carneiro, Flávio Queiroz-Telles

“…Statistical significance was found for premedication use from the first dose of ABLC in relation to the onset of infusion reactions (P = 0.006). Multivariate analysis revealed that ABLC, when compared to liposomal AMB (L-AMB), and neutropenia were associated with a higher risk of developing IRSE (odds ratio [OR] 3.04, P = 0.008; and OR 11.02, P = 0.025, respectively). …”
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Characterization of adult T-cell leukemia/lymphoma patients with specific skin lesions in a tertiary dermatological service in Brazil by Mariana Valente, José Antonio Sanches, Youko Nukui, Jade Cury-Martins, Bruno Castro Souza, Juliana Pereira, Denis Miyashiro

“…Acute and chronic unfavorable forms had worse prognoses, with median overall survival of 23.3 and 34.1 months, respectively (p = 0.0011). After multivariate analysis, Shimoyama classification (acute) and urea levels were associated with poorer prognoses.ConclusionWe described a large Brazilian cohort of ATLL with cutaneous involvement. …”
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Evaluating risk factors for Trastuzumab-Deruxtecan Pneumonitis in patients with metastatic breast cancer by Jonathan Henricks, Tyler Haddad, Omair Ahmed, Jonathan Schoenhals, Pavnesh Kumar, Ryan Wilson, Jianing Ma, Jing Gennie Wang, Michael Wert, Vincent Esguerra, Ian Bentley, Kai Johnson, Daniel Stover, Sachin R. Jhawar, Margaret Gatti-Mays, Kevin Ho

“…Multiple pre-treatment variables were not found to be associated with T-DXd pneumonitis, including chest imaging abnormalities (41.9% vs. 47.8%, p = 0.59), prior immune checkpoint inhibitor treatment (16.0% vs. 8.7%, p = 0.50) and prior chest or breast radiation (61.5% vs. 47.8%, p = 0.20). On multivariate analysis, prior treatment with abemaciclib remained significantly associated with T-DXd pneumonitis (OR 3.25 [1.07–9.11], p = 0.04), while neither pre-treatment chest imaging abnormalities nor prior chest or breast radiation were associated (OR 1.60 [0.62–4.20], p = 0.33); OR 0.51 [0.20–1.33], p = 0.17). …”
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Modified Endothelial Activation and Stress Index: A New Predictor for Survival Outcomes in Classical Hodgkin Lymphoma Treated with Doxorubicin-Bleomycin-Vinblastine-Dacarbazine-Bas... by Fazıl Çağrı Hunutlu, Hikmet Öztop, Vildan Gürsoy, Tuba Ersal, Ezel Elgün, Şeyma Yavuz, Selin İldemir Ekizoğlu, Azim Ali Ekizoğlu, Vildan Özkocaman, Fahir Özkalemkaş

“…Additionally, multivariate analysis showed that the independent variables affecting PFS included the nodular sclerosing subtype (HR: 0.4), bone marrow involvement (HR: 2.6), and elevated mEASIX (HR: 3.1). …”
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Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon by Xiaogang Zhu, Hua Shen, Fei Gao, Sijing Wu, Qian Ma, Shuo Jia, Ziwei Zhao, Shan Tong, Zhihao Zhang, Yujie Zhou

“…The major adverse cardiovascular events (MACE) occurred in 39 patients (9.3%) out of 421 patients. Multivariate analysis showed that the risk of MACE approximately doubles with age >50 years (hazard ratio (HR) = 2.2, 95% CI: 1.0 to 4.9, and P=0.042), hypertension (HR = 2.1, 95% CI: 1.1 to 4.2, and P=0.021), and dyslipidemia (HR = 2.0, 95% CI: 1.0 to 3.9, and P=0.042). …”
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Early Changes in Blood Urea Nitrogen (BUN) Can Predict Mortality in Acute Pancreatitis: Comparative Study between BISAP Score, APACHE-II, and Other Laboratory Markers—A Prospective... by Elizabeth Pando, Piero Alberti, Rodrigo Mata, María José Gomez, Laura Vidal, Arturo Cirera, Cristina Dopazo, Laia Blanco, Concepción Gomez, Mireia Caralt, Joaquim Balsells, Ramón Charco

“…Rise in BUN was the only score related to mortality on the multivariate analysis (p=0.000, OR: 12.7; CI 95%: 4.2−16.6). …”
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Development and validation of a nomogram for predicting immune-mediated colitis in lung cancer patients treated with immune checkpoint inhibitors: a retrospective cohort study in C... by Qianjie Xu, Xiaosheng Li, Yuliang Yuan, Guangzhong Liang, Zuhai Hu, Wei Zhang, Ying Wang, Haike Lei

“…On the basis of the results of the multivariate analysis, a nomogram prediction model was developed. …”
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