Correlation Between Systemic Inflammation, Gut Microbiome Dysbiosis and Postoperative Complications After the Modified Whipple Procedure by Gelu Mihai Breaza, Florin Emil Hut, Octavian Cretu, Simona-Alina Abu-Awwad, Ahmed Abu-Awwad, Laurențiu Vasile Sima, Radu Gheorghe Dan, Cristina Ana-Maria Dan, Raluca Maria Closca, Flavia Zara

“…Patients exhibiting both dysbiosis and elevated inflammation had the highest complication rate (60%). Multivariate analysis identified diabetes, elevated IL-6, and dysbiosis as independent predictors of adverse outcomes. (4) Conclusions: Postoperative complications after the modified Whipple procedure are influenced by systemic inflammation and gut dysbiosis. …”
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A Study of Correlation of Adiponectin Levels in Metabolic Syndrome by Apurv Singhal, Vedpal Singh Punia, Akash Bharti, Shaavi Mittal, Praveen Raman Mishra, Prem Kuma

“…The authors discovered that lower adiponectin levels were statistically significantly linked with the majority of the characteristics. In a multivariate analysis, the serum adiponectin content was found to be significantly inversely associated to systolic blood pressure (r=-0.262; p<0.050), BMI (r=-0.288; p<0.050), total cholesterol (r=-0.515; p<0.001), and low-density lipoprotein (r=-0.305; p<0.050) in the study participants. …”
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Incidence of seroma and postoperative complications after breast surgery before and during the Covid-19 pandemic: results from a retrospective multicenter analysis by Maximilian Heinz Beck, Izabela A. Brachaczek, Pimrapat Gebert, Jens-Uwe Blohmer, Askin C. Kaya, Julia S. M. Zimmermann, Julia C. Radosa, Maria M. Karsten

“…However, complications such as erythema, wound infection, and wound healing disorders were notably more frequent during the SARS-CoV-2 pandemic. Multivariate analysis revealed that increasing patient age, smoking, breast implant reconstruction, axillary lymph node dissection, and previous radiation were significant clinical risk factors for seroma development. …”
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Free Fatty Acids in CSF and Neurological Clinical Scores: Prognostic Value for Stroke Severity in ICU by Sayed Gaber, Sherine Ibrahim ElGazzar, Mahmoud Qenawi, Nora Ismail Mohamed Abbas

“…Univariate and multivariate analysis were used to evaluate the stroke outcome according to FFA levels in CSF. …”
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Pan-cancer characterization of m6A-mediated regulation of T cell exhaustion dynamics and clinical relevancies in human cancers by Weiping Ji, Ye Fang, Liwei Chen, Yitong Zheng, Yifei Pei, Changqiu Mei, Meng Zhou

“…The TexLm6AL subtype, characterized by low m6A activity and low TEX, correlated with high immune infiltration, increased cytolytic activity, and favorable survival, whereas the TexLm6AH and TexHm6AH subtypes with higher m6A activity were associated with poorer survival. Multivariate analysis confirmed the prognostic value of this classification independent of traditional clinical factors. …”
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Evaluation of in-office tooth whitening treatment with violet LED: protocol for a randomised controlled clinical trial by Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Maria Fernanda Setúbal Destro Rodrigues, Ana Eliza Castanho Garrini dos Santos, Marcelo Mendes Pinto, Dácio Antonio Pantano Junior, Aldo Brugnera Jr, Fátima Antonia Aparecida Zanin

“…After determining the normality of the data, the Kruskal-Wallis test will be used for non-parametric data. Multivariate analysis of variance (MANOVA) and the Wilcoxon test will be used for comparing data from the PIDAQ.Ethics and dissemination This protocol has been approved by the Human Research Ethics Committee of UniversidadeNove de Julho (certificate: 2.034.518). …”
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Predictors of failure of DISE-directed adenotonsillectomy in children with sleep disordered breathing by Noura Alsufyani, Andre Isaac, Manisha Witmans, Paul Major, Hamdy El-Hakim

“…Small tonsil size on DISE correlated with treatment failure (r = −0.180, p < 0.001). Multivariate analysis identified age greater than 7 years (OR = 1.799, [95% CI 1.040–3.139], p = 0.039), obesity (OR = 2.032, [95% CI 1.043–3.997], p = 0.040), chronic rhinitis (OR = 1.334, [95% CI 1.047–1.716], p = 0.025), deviated nasal septum (OR = 1.745, [95% CI 1.062–2.898], p = 0.031) and tonsil size (OR = 0.575, [95% CI 0.429–0.772], p < 0.01) as independent predictors of treatment failure. …”
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Clinical Aspects and Prognosis Evaluation of Cirrhotic Patients Hospitalized with Acute Kidney Injury by Célio Geraldo de Oliveira Gomes, Marcus Vinicius Melo de Andrade, Ludmila Resende Guedes, Henrique Carvalho Rocha, Roberto Gardone Guimarães, Fernando Antônio Castro Carvalho, Eduardo Garcia Vilela

“…Mortality was 28.6% in 30 days and 44.9% in three months. In multivariate analysis, variables that were associated independently to mortality were lack of response to expansion treatment and Child-Pugh score. …”
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Hubungan Faktor Risiko dengan Kejadian Pre-Eklampsia Berat di RSUP Dr. M. Djamil Padang by Nurulia Muthi Karima, Rizanda Machmud, Yusrawati .

“…While the results of the multivariate analysis using logistic regression found that maternal age&gt; 35 years was a risk factor for the incidence of severe pre-eclampsia with p = 0.034. …”
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Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China by Xiao-Juan YU, Feng YU, Di Song, Su-Xia Wang, Yan Song, Gang Liu, Ming-Hui Zhao

“…During followup, 8 patients died due to severe infection, 17 patients had doubling of serum creatinine, and 44 had end-stage renal disease. In multivariate analysis, male, elevated serum creatinine, and decreased hemoglobin were independently associated with poor renal outcomes. …”
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Potential Risk Factors for In-Hospital Mortality in Patients with Moderate-to-Severe Blunt Multiple Trauma Who Survive Initial Resuscitation by Neslihan Yucel, Tuba Ozturk Demir, Serdar Derya, Hakan Oguzturk, Murat Bicakcioglu, Funda Yetkin

“…Forty-three (22%) of the 195 patients died in hospital. Multivariate analysis identified low blood pH (odds ratio [OR] 6.580, 95% confidence interval [CI] 1.12-38.51), high serum lactate level (OR 1.041, 95% CI 1.01-1.07), high ISS (OR 1.109, 95% CI 1.06-1.16), high APACHE II score (OR 1.189, 95% CI 1.07-1.33), traumatic brain injury (TBI) (OR 4.358, 95% CI 0.76-24.86), severe hemorrhage (OR 5.314, 95% CI 1.07-26.49), and coagulopathy (OR 5.916, 95% CI 1.17-29.90) as useful predictors of acute in-hospital mortality. …”
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Risk factors for malignancy in pediatric subacute/chronic focal craniocervical lymphadenopathy by Yishai Haimi-Cohen, Yishai Haimi-Cohen, Yishai Haimi-Cohen, Eyal Elron, Eyal Elron, Lital Oz-Alcalay, Lama Hejly, Roy Hod, Roy Hod, Liat Ashkenazi-Hoffnung, Liat Ashkenazi-Hoffnung, Liat Ashkenazi-Hoffnung

“…Twenty percent of the children older than 12.5 years and 12% of those with a lymph node diameter &gt;31 mm were diagnosed with malignancy. Multivariate analysis showed associations with malignancy of older age and larger lymph nodes; the respective odds ratios were 1.649 (95%CI: 1.197–2.349, p = 0.004) for every 3 years and 2.080 (95%CI: 1.292–3.330, p = 0.002) for every one centimeter.ConclusionsOlder age and increased nodal size can help identify children with focal craniocervical lymphadenopathy who are at increased risk for malignancy and for whom surgical intervention should be strongly considered.…”
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Prognostic evaluation of non-muscle invasive bladder cancer with P-CRP and its nomogram by Junyun Wu, Zhixuan Deng, Xu Lei, Zhiyao Xu, Chenxi Tan, Yunqiao Tang, Xi Sheng, Ning Yang

“…Then, the Nomogram was used to visualize the results of the multivariate analysis that were statistically significant and related to the RFS of NMIBC patients. …”
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CT-based skeletal muscle loss predicts long term prognosis in patients with distal cholangiocarcinoma undergone pancreaticoduodenectomy by Guangzhen Qu, Shao-Cheng Lyu, Yong Zhang, Kun Gao, Chuanguo Zhou

“…The best cut-off values of SML were − 4.01% and − 5.99% for OS and RFS. In multivariate analysis, tumor size  > 2.0 cm (hazard ratio (HR) = 1.90, P = 0.017), poor differentiation (hazard ratio (HR) = 2.80, P > 0.001), higher SML (SML ≤ − 4.01%) (hazard ratio (HR) = 3.60, P  < 0.001), lymph metastasis (hazard ratio (HR) = 4.00, P  < 0.001) and vascular invasion (hazard ratio (HR) = 2.10, P  = 0.013) were independent risk factors forOS. …”
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Assessment of Atrial Conduction Times in Patients with Newly Diagnosed Parkinson’s Disease by Yiğit Çanga, Ayşe Emre, Gülbün Asuman Yüksel, Mehmet Baran Karataş, Nizamettin Selçuk Yelgeç, Ufuk Gürkan, Ali Nazmi Çalık, Hülya Tireli, Sait Terzi

“…There were significant positive correlations between disease severity (UPDRS score) and PWD (r=0.34, p=0.041), left intra-atrial (r=0.39, p=0.005), and interatrial EMD (r=0.35, p=0.012). By multivariate analysis, PWD (OR: 1.13, 95% CI: 1.02–1.25; p=0.017), LA volume index (OR: 1.19, 95% CI: 1.02–1.37; p=0.021), left intra-atrial (OR: 1.12, 95% CI: 1.01–1.24; p=0.041), and interatrial EMD (OR: 1.08, 95% CI: 1.01–1.16; p=0.026) were found as independent predictors of PD. …”
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Impact of Nasal Anatomical Variation Subtype on Surgical Outcomes for Rhinogenic Contact Point Headache by Salvatore Lavalle, Annalisa Pace, Giuseppe Magliulo, Mario Lentini, Jerome Rene Lechien, Christian Calvo-Henriquez, Federica Maria Parisi, Giannicola Iannella, Antonino Maniaci, Daniela Messineo

“…All nasal subtypes improved with surgery but concha bullosa had worse VAS outcomes (4.0) than septal deviation (1.8, <i>p</i> < 0.001) or spur (1.73, <i>p</i> < 0.001). Multivariate analysis found nasal anomalies predicted postoperative VAS scores (<i>p</i> < 0.001) but not headache frequency (<i>p</i> = 0.255). …”
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Predictors of Cardiovascular Autonomic Neuropathy Onset and Progression in a Cohort of Type 1 Diabetic Patients by M. Matta, A. Pavy-Le Traon, S. Perez-Lloret, C. Laporte, I. Berdugo, N. Nasr, H. Hanaire, J. M. Senard

“…A bivariate analysis indicated that only BMI and exposure to selective serotonin reuptake inhibitors (SSRIs) were significantly different in both groups. A multivariate analysis indicated that lower BMI (OR: 0.15, CI 95%: 0.05–0.48, p=0.003) and SSRI exposure (OR: 4.18, CI 95%: 1.03–16.97, p=0.04) were the sole predictors of CAN deterioration. …”
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Non-carbapenem-producing carbapenem-resistant Pseudomonas aeruginosa in children: Risk factors, molecular epidemiology, and resistance mechanism by Lijun Yin, Lu Lu, Leiyan He, Gangfeng Yan, Guoping Lu, Xiaowen Zhai, Chuanqing Wang

“…Methods: To assess epidemiology, molecular characteristics, and resistance mechanisms, virulence-associated genes were analyzed, alongside multi locus sequence typing (MLST), PCR, and qRT-PCR. Finding: Multivariate analysis identified prolonged hospitalization (OR: 1.026; 95 % CI: 1.004–1.049; P = 0.023) and increased exposure to enzyme inhibitor complex preparations (OR: 3.165; 95 % confidence interval [CI]: 1.113–8.999; P = 0.031) as independent risk factors for CRPA healthcare-associated infections (HAIs). …”
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Factors Associated with HIV Testing among Male Students Who Have Engaged in Sexual Behaviour in Zhejiang Province, China by Zhongrong Yang, Hui Wang, Qiaoqin Ma, Weiyong Chen, Xiang Zhao, Tingting Jiang, Wanjun Chen, Xin Zhou, Lin Chen

“…The results of multivariate analysis demonstrated that the participants who were in the junior grade level (adjusted odds ratio (AOR) = 1.59, 95% confidence interval (95% CI): 1.10–2.30) exhibited acceptance to male homosexual behaviour (AOR = 1.73, 95% CI: 1.19–2.52), had been exposed to testing publicity in the previous year (AOR = 1.51, 95% CI: 1.06–2.15), had been exposed to self-risk assessment for HIV infection (AOR = 2.66, 95% CI: 1.99–3.55), had male or bisexual partners (AOR = 1.60, 95% CI: 1.05–2.46), had a score for the scale indicating awareness of different testing methods between 2 and 5 (AOR = 2.19, 95% CI: 1.51–3.16) or greater than 6 (AOR = 1.49, 95% CI: 1.01–2.66), and had a score for the scale indicating knowledge of different testing facilities between 3 and 5 (AOR = 1.63, 95% CI: 1.00–2.66) were inclined to engage in HIV testing. …”
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The correlation between coagulation biomarkers, bone turnover markers, and bone mineral density in Chinese adults aged ≥ 50 years by Zhengming Wang, Rui Wang, Haiya Ge, Yong Gu, Sicheng Xian, Laijun Yan, Guoqing Du, Zhibi Shen, Shuaijie Lv, Hongsheng Zhan, Zhengyan Li

“…D-dimer exhibited the most significant positive association with age and the most pronounced negative correlation with the BMD of Ward’s triangle (r = 0.322, p < 0.001; r = –0.298, p < 0.001; respectively). 25-(OH)D and calcium were related to coagulation biomarkers. Multivariate analysis demonstrated that age was positively associated with D-dimer levels (odd ratio [OR] = 1.046, p = 0.007), while the BMD of Ward’s triangle was negatively related to D-dimer levels (OR = 0.004, p = 0.0017). …”
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