The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions by Xuegang Li, Haijian Jiang, Xu Wang, Shuping Zhong

“…However, only sclerostin had correlation with the CBM scores in multivariate analysis (ρ = -0.040, p < 0.001). Conclusions In the r-axSpA patients with fatty lesions, serum sclerostin levels are declined. …”
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Role of postoperative radiotherapy in pT3N0 rectal cancer: A risk‐stratification system based on population analyses by Yun‐xia Huang, Yan‐zong Lin, Jin‐luan Li, Xue‐qing Zhang, Li‐rui Tang, Qing‐yang Zhuang, Fei‐fei Lin, Xi‐jin Lin, Jun‐xin Wu

“…The overall 5‐year CSS was 86.31%. Multivariate analysis showed that age (P < 0.001), tumor differentiation (P = 0.044), number of nodes resected (P = 0.032), marital status (P = 0.005), and radiotherapy (P = 0.006) were independent prognostic factors for CSS. …”
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Comparative efficacy of lumbar and pelvic support on pain, disability, and motor control in women with postpartum pelvic girdle pain: a three-armed randomized controlled trial by Fahimeh-Sadat Jafarian, Mahmonir Jafari-Harandi, Gillian Yeowell, Ebrahim Sadeghi-Demneh

“…Repeated-measures multivariate analysis of variance (MANOVA) was applied to determine the statistical significance between groups. …”
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Circulatory Immune Cells in Cushing Syndrome: Bystanders or Active Contributors to Atherometabolic Injury? A Study of Adhesion and Activation of Cell Surface Markers by Gloria Aranda, Cristina Lopez, Rebeca Fernandez-Ruiz, Yaiza Esteban, Guillermo Garcia-Eguren, Mireia Mora, Irene Halperin, Gregori Casals, Joaquim Enseñat, Felicia A. Hanzu

“…NK-Lym correlated with c-LDL (r = 0.433, p=0.039) and CD15+ N with hs-CRP (r = 0.446, p=0.037). In multivariate analysis, Leuc, N, and MN depended on BMI (p=0.021), WC (p=0.002), and WHR (p=0.014), while CD15+ and CD15+CD16+ N on hypercortisolism and CS (p=0.035). …”
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Circulating Galectin-3 and Aldosterone for Predicting Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation by Zhong-bao Ruan, Run-feng Gao, Fei Wang, Ge-cai Chen, Jun-guo Zhu, Yin Ren, Li Zhu

“…Univariate and multivariate analysis showed that Gal-3 (HR=1.28, 95% CI: 1.04-1.56, p=0.02) and ALD (OR=1.02, 95% CI: 1.00-1.03, p<0.03) were significantly associated with AF recurrence after RFCA. …”
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Ultrasound Features of <i>Helicobacter pylori</i>-Related Gastritis by Fulvia Terracciano, Antonella Marra, Veronica Nassisi, Chiara Lillo, Fabrizio Bossa, Sonia Carparelli, Francesco Cocomazzi, Maria Rosa Valvano, Giuseppe Losurdo, Alfredo Di Leo, Francesco Perri

“…<b>Results</b>: SLT and reduced gastric motility were significantly increased in the <i>H. pylori</i> gastritis group (<i>p</i> < 0.001). Multivariate analysis identified SLT as the only significant independent predictor of <i>H. pylori</i> gastritis (<i>p</i> < 0.001). …”
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Plasma S100A8/A9 level predicts response to immune checkpoint inhibitors in patients with advanced non-small cell lung cancer by Tadahiro Kuribayashi, Rie Kinoshita, Kiichiro Ninomiya, Go Makimoto, Toshio Kubo, Kammei Rai, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Yoshinobu Maeda, Katsuyuki Kiura, Shinichi Toyooka, Masakiyo Sakaguchi, Kadoaki Ohashi

“…The TTF and OS were worse in patients with high plasma S100A8/A9 levels (≥ 2.475 µg/mL) (median TTF: 4.3 vs. 8.5 months, p = 0.009; median OS: 15.4 vs. 38.0 months, p = 0.001). Multivariate analysis revealed that PS ≥ 2, liver metastasis, and high plasma S100A8/A9 levels were significantly associated with short TTF and OS. …”
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Prevalence of anaemia and its associated factors among HIV-infected adults at the time of ART initiation at Debre Markos Comprehensive Specialized Hospital, Northwest Ethiopia: a r... by Agazhe Aemro, Belayneh Shetie Workneh, Enyew Getaneh Mekonen, Mulugeta Wassie, Basazinew Chekol

“…The overall prevalence of anaemia among HIV-infected adults at the time of ART initiation was 35.04% (95% CI: 30.84% to 39.49%). After multivariate analysis, an increased risk of anaemia was seen among males (adjusted OR (AOR)=2.45; 95% CI: 1.51 to 3.98); those not attending formal education (AOR=2.38; 95% CI: 1.12 to 5.05); those who had baseline CD4+ T cell count ≤200 cells/mm3 (AOR=4.67; 95% CI: 2.78 to 7.85); had body mass index (BMI) &lt;18.5 kg/m2 (AOR=2.43; 95% CI: 1.42 to 4.16) and had ambulatory/bedridden baseline functional status (AOR=2.69; 95% CI: 1.41 to 5.12).Conclusion The current study showed that a significant proportion of HIV-infected adults developed anaemia at the time of ART initiation. …”
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The significance of risk stratification through nomogram-based assessment in determining postmastectomy radiotherapy for patients diagnosed with pT1 − 2N1M0 breast cancer by Chao Wei, Jie Kong, Huina Han, Xue Wang, Zimeng Gao, Danyang Wang, Andu Zhang, Jun Zhang, Zhikun Liu

“…Result The median follow-up period was 98 months, Patients who received PMRT demonstrated significantly improved 5-year and 8-year OS and DFS compared to those who did not (P < 0.001). Multivariate analysis revealed that age, primary tumor site, positive lymph node, stage, and Ki-67 level independently influenced OS, while age, primary tumor site, and stage independently affected DFS. …”
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Clinical Characteristics and Short-Term Outcomes of HIV Patients Admitted to an African Intensive Care Unit by Arthur Kwizera, Mary Nabukenya, Agaba Peter, Lameck Semogerere, Emmanuel Ayebale, Catherine Katabira, Samuel Kizito, Cecilia Nantume, Ian Clarke, Jane Nakibuuka

“…The mean Acute Physiologic and Chronic Health Evaluation (APACHE II) score was 24. At multivariate analysis, APACHE II (OR 1.24 (95% CI: 1.1–1.4, P=0.01)), mechanical ventilation (OR 1.14 (95% CI: 0.09–0.76, P=0.01)), and ARDS (OR 4.5 (95% CI: 1.07–16.7, P=0.04)) had a statistically significant association with mortality. …”
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A Novel Nomogram for Predicting the Risk of Pneumonia After Intracerebral Hemorrhage by Sun Y, Zhang L, Huang B, He Q, Hu B

“…Thirty percent of qualified patients were placed in the validation group (n=763) while seventy percent of them were randomly placed in the training group (n=1784). In the multivariate analysis, ten variables were included in the model: age (β= 0.023, P< 0.001), hospital days (β=0.392, P< 0.001), baseline mRS score (β=0.484, P< 0.001), baseline GCS score (β=− 0.285, P< 0.001), hs-CRP (β=0.328, P< 0.001), hematoma volume (β=0.376, P< 0.001), brainstem hemorrhage (β=0.956, P=0.002), intraventricular hemorrhage (β=0.629, P=0.001), and β-blocker (β=0.899, P< 0.001) In the training subset, the areas under curve were 0.805 (95% CI, 0.773– 0.833). …”
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Association between TCF7L2 Genotype and Glycemic Control in Diabetic Patients Treated with Gliclazide by Martin Javorský, Eva Babjaková, Lucia Klimčáková, Zbynek Schroner, Jozef Židzik, Mária Štolfová, Ján Šalagovič, Ivan Tkáč

“…No significant difference in ΔHbA1c between the patients with CC genotype and the T-allele carriers was observed in Group 2. In the multivariate analysis, only the TCF7L2 genotype (P=0.006) and the baseline HbA1c (P<0.001) were significant predictors of ΔHbA1c. …”
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Cross-Sectional Relationship between Carotid-Femoral Pulse Wave Velocity and Biomarkers in Vascular-Related Diseases by Jinbo Liu, Kuanting Wang, Huan Liu, Hongwei Zhao, Wei Huang, Na Zhao, Lihong Li, Hongyu Wang

“…Positive correlation between CFWV and Hcy, Log UAE, and Log NT-proBNP was found in the entire study group (r = 0.109, 0.196, and 0.119, all p<0.05). Multivariate analysis showed that pulse pressure, age, fasting plasma glucose, diastolic blood pressure, body mass index, and Log UAE were independent associating factors of CFPWV in all subjects (β = 0.334, p<0.001; β = 0.333, p<0.001; β = 0.126, p=0.004; β = 0.137, p=0.003; β = −0.142, p=0.002; and β = 0.098, p=0.031). …”
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Characterization of meat quality, storage stability, flavor-related compounds, and their relationship in Korean Woorimatdag No. 2 chicken breast meat during cold storage by Yousung Jung, Soomin Oh, Sangrok Lee, Hee-Jeong Lee, Hyo-Jun Choo, Cheorun Jo, Ki-Chang Nam, Jun-Heon Lee, Aera Jang

“…Interestingly, multivariate analysis highlighted several volatile compounds, including methyl salicylate (day 1), dodecanal (day 3), naphthalene (day 5), and 2,4-decadienal (day 7) as potential biomarkers to distinguish between WRMD2 and CB on each storage day. …”
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Tracheostomy-related indications, early complications and their predictors among patients in low resource settings: a prospective cohort study in the pre-COVID-19 era by Nyanzi, Daniel J., Daniel, Atwine, Kamoga, Ronald, Birungi, Caroline, Nansubuga, Caroline A., Nyaiteera, Victoria, Nakku, Doreen

“…For predictors of early tracheostomy complications, bivariate and multivariate analysis models were ftted using binomial regression in STATA 13.0 software. …”
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Primary Angioplasty in a Catastrophic Presentation: Acute Left Main Coronary Total Occlusion—The ATOLMA Registry by A. Gutiérrez-Barrios, L. Gheorghe, S. Camacho-Freire, F. Valencia-Serrano, D. Cañadas-Pruaño, G. Calle-Pérez, I. Alarcón de la Lastra, E. Silva, D. García-Molinero, A. Agarrado-Luna, R. Zayas-Ruedas, R. Vázquez-García, A. Serra

“…At one-year and at the final follow-up, 18 patients (39%) were alive, including four cases successfully transplanted. Multivariate analysis showed that postprocedural TIMI flow was the only independent predictor of in-hospital mortality (OR 0.23, (95% CI 0.1–0.36), p<0.001). …”
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A preliminary study on the prognostic significance of cysteine-rich EGF ligand domain 2 protein (CRELD2) in patients with triple negative breast cancer by Mehmet Zahid Kocak, Murat Araz, Siddika Findik, Aykut Demirkiran, Mustafa Korkmaz, Melek Karakurt Eryilmaz, Mehmet Artac

“…The median OS was 17.2 (95% CI: 13.7–22.3) months in the CRELD2-positive group and 24.7 (95% CI: 21.8–29.6) months in the CRELD2-negative group (P = 0.02). In multivariate analysis, CRELD2 status (negative vs positive) (hazard ratio [HR]: 0.50, 95% CI: 0.38–0.96, P = 0.02) was determined to be a risk factor for OS and CRELD2 status (negative vs positive) (HR: 0.82, 95% CI: 0.33–0.96, P = 0.01) was defined as a risk factor for PFS in patients with metastatic TNBC. …”
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Knowledge and attitudes towards Alzheimer’s disease and related dementias among Nigerian medical and nursing students: a comparative study by Tobi Olajide, Favour Ajao, Inioluwa Joshua, Abigail Oyedokun, Ayosubomi Odubiyi, Oluwadabira Adewara, Feziechi Anele, Ayomide Fatola, Samuel Ayeni, Nneka Amakom, Oluwanifemi Osakuade, Oluwabunmi Adeyeye, Chidera Ezeh, Gbenga Shittu, Rashidat Mufutau, Serena Atoyebi, Michael Apata, Sandra Obatowon, Aminat Abdul, Jesufemi Adeyeye, Akin Ojagbemi

“…Data were collected using the Alzheimer’s Disease Knowledge Scale (ADKS) and Dementia Care Attitude Scale (DCAS). Multivariate analysis of variance (MANOVA) was used to compare mean scores between these students. …”
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Evaluation of Health Science Students&rsquo; Knowledge, Attitudes, and Practices Toward Artificial Intelligence in Northern Saudi Arabia: Implications for Curriculum Refinement and... by ALruwail BF, Alshalan AM, Thirunavukkarasu A, Alibrahim A, Alenezi AM, Aldhuwayhi TZA

“…Additionally, multivariate analysis was employed to identify associated factors.Results: The present study demonstrated low knowledge, attitude, and practices among 55.7%, 37.0%, and 50.3% of health science students. …”
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KLRB1 expression in nasopharyngeal mucosa as a prognostic biomarker in COVID-19 patients by Marilina García-Aranda, María Ángeles Onieva, Desirée Martín-García, Raúl Quirós, Inmaculada López, María Padilla-Ruiz, Teresa Téllez, Beatriz Martínez-Gálvez, María Luisa Hortas, Alberto García-Galindo, José González-Gomariz, Rubén Armañanzas, Francisco Rivas-Ruiz, Alfonso Serrano, Isabel Barragán-Mallofret, Maximino Redondo

“…Comparative analysis identified four genes, with KLRB1 (Killer cell lectin like receptor B1) (Odds Ratio OR 0.5, 95% CI: 0.27–0.96), along with age (OR 3.3, 95% CI: 1.25–8.93) emerging as independent prognostic markers in multivariate analysis. These findings were validated using qRT-PCR in an independent cohort of 168 patients hospitalized in 2022. …”
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