Raman Microspectral Study and Classification of the Pathological Evolution of Breast Cancer Using Both Principal Component Analysis-Linear Discriminant Analysis and Principal Compo... by Heping Li, Yu Ren, Fan Yu, Dongliang Song, Lizhe Zhu, Shibo Yu, Siyuan Jiang, Shuang Wang

“…The present study demonstrates that Raman spectroscopy combined with multivariate analysis technology has considerable potential for improving the efficiency and performance of breast cancer diagnosis.…”
Get full text

Negative Expression of DSG1 and DSG2, as Prognostic Biomarkers, Impacts on the Overall Survival in Patients with Extrahepatic Cholangiocarcinoma by Shu Xu, Shengfu Huang, Daiqiang Li, Qiong Zou, Yuan Yuan, Zhulin Yang

“…In comparison to patients with negative DSG1 and/or DSG2 expression, the average overall survival time of those with positive expression was significantly longer (P=0.000). Cox multivariate analysis revealed that negative DSG1 and DSG2 expressions were independent of poor prognosis factors in EHCC patients. …”
Get full text

Vision Loss and Recovery after Baerveldt Aqueous Tube Shunt Implantation by Esther Lee Kim, Jeffrey Tran, Marc Töteberg-Harms, Jasdeep Chahal, Douglas Rhee, Vikas Chopra, Brian Francis

“…Of these 63 eyes, 18 had no identifiable cause of vision loss. On multivariate analysis, poorer Snellen VA on postoperative day 1 (POD1) was found to be a significant risk factor for long-term vision loss (p=0.005). …”
Get full text

18F-FDG-PET/CT can be used to predict distant metastasis in hypopharyngeal squamous cell carcinoma by Shinsuke Suzuki, Satoshi Toyoma, Tomoe Abe, Tentaro Endo, Teppei Kouga, Yohei Kaswasaki, Takechiyo Yamada

“…The univariate analysis showed that T and N classification, clinical stage, and SUVmax were significantly related to distant metastasis. However, in multivariate analysis, an SUVmax ≥ 13.9 was the only independent predictor of distant metastasis. …”
Get full text

Evaluation of Risk Factors for Antibiotic Resistance in Patients with Nosocomial Infections Caused by Pseudomonas aeruginosa by Meliha Cagla Sonmezer, Gunay Ertem, Fatma Sebnem Erdinc, Esra Kaya Kilic, Necla Tulek, Ali Adiloglu, Cigdem Hatipoglu

“…Various risk factors were detected for each antibiotic in the univariate analysis. In the multivariate analysis, previous cefazolin use was found as an independent risk factor for the development of imipenem resistance (OR = 3.33; CI 95% [1.11–10.0]; p = 0.03), whereas previous cerebrovascular attack (OR = 3.57; CI 95% [1.31–9.76]; p = 0.01) and previous meropenem use (OR = 4.13; CI 95% [1.21–14.07]; p = 0.02) were independent factors for the development of meropenem resistance. …”
Get full text

Stereotactic body radiation therapy for hepatocellular carcinoma: Practice patterns, dose selection and factors impacting survival by Jared R. Robbins, Ryan K. Schmid, Abdulrahman Y. Hammad, Thomas Clark Gamblin, Beth A. Erickson

“…Various factors influenced dose selection including tumor size (P < 0.001), tumor stage (P = 0.002), and facility case volume (<0.001). On multivariate analysis, low BED (<75 Gy, HR 2.537, P < 0.001; 75‐100 Gy, HR 1.986, P = 0.007), increasing tumor size (HR 1.067, P = 0.032), elevated AFP (HR 1.585, P = 0.019), stage 3 (HR 1.962, P < 0.001), low‐volume facilities (1‐5 cases HR 1.687, P = 0.006), and a longer time interval from diagnosis to SBRT (>2 to ≤4 months, HR 1.456, P = 0.048; >4 months, HR 2.192, P < 0.001) were associated with worse survival. …”
Get full text

Risk of Multidrug Resistant Bacteria Acquisition in Patients with Declared β-Lactam Allergy during Hospitalization in Intensive Care Unit: A Retrospective Cohort Study (2007-2018) by Alessio Strazzulla, Maria Concetta Postorino, Nabil Belfeki, Laura Iordache, Astrid de Pontfarcy, Aurelia Pitsch, Pierre Leroy, Sebastien Jochmans, Mehran Monchi, Sylvain Diamantis

“…Female gender was the only factor associated with β-lactam allergy at the multivariate analysis. Conclusions. This study confirms that patients with declared β-lactam allergy had not a higher risk of ESBL bacterial acquisition during hospitalization in ICU. …”
Get full text

Association of inflammatory markers and endothelial dysfunction with depression in patients with ischemic cerebrovascular disease by Julcileia Imara D De Carvalho Muenho, Marisol Peña Sanchez, Alina González-Quevedo Monteagudo, Danay Martínez Puentes, Sergio González García, Marianela Arteche Prior, Asdrubal Arias Morales

“…C-reactive protein and C3 were statistically correlated with the Hamilton test score. In the multivariate analysis, C-reactive protein showed an independent association with the degree of depression by the Hamilton test.…”
Get full text

Prognostic Impact of Potentially Curative Resection for Synchronous Peritoneal Carcinomatosis with Lavage Cytology Positivity in Colorectal Cancer: A Retrospective Observational St... by Kentaro Sato, Shimpei Matsui, Tomohiro Chiba, Tatsuki Noguchi, Takashi Sakamoto, Toshiki Mukai, Tomohiro Yamaguchi, Takashi Akiyoshi, Yosuke Fukunaga

“…Univariate analysis for 3-year recurrence revealed that lavage cytology-positive status was not an explanatory variable (hazard ratio: 1.552, 95% confidence interval: 0.83-2.902, P = 0.169). Multivariate analysis identified colon cancer as an independent risk factor of recurrence. …”
Get full text

Increased Serum ANGPTL8 Concentrations in Patients with Prediabetes and Type 2 Diabetes by Yanhua Yin, Xiaoying Ding, Liang Peng, Yanqiang Hou, Yunxia Ling, Mingyu Gu, Yufan Wang, Yongde Peng, Haiyan Sun

“…Serum ANGPTL8 was positively correlated with FPG, fasting C-peptide, and postprandial C-peptide and negatively correlated with BETA/IR when adjusted for age and BMI. Multivariate analysis suggested FPG and fasting C-peptide as independent factors associated with serum ANGPTL8 levels. …”
Get full text

Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function: The Multiethnic Study of Athero... by Jennifer S. Anderson, Jennifer A. Nettleton, W. Gregory Hundley, Michael Y. Tsai, Lyn M. Steffen, Rozenn N. Lemaitre, David Siscovick, João Lima, Martin R. Prince, David Herrington

“…Results. Results of multivariate analysis showed no statistically significant associations of plasma omega-6 or omega-3 levels with cardiac magnetic resonance imaging measures. …”
Get full text

Correlation of Serum Albumin Level to Lung Ultrasound Score and Its Role as Predictors of Outcome in Acute Respiratory Distress Syndrome Patients: A Prospective Observational Study by Souvik Chaudhuri, Sagar S. Maddani, Shwethapriya Rao, Sirish Gauni, N. R. Arjun, Pratibha Todur, Nitin Gupta

“…The cut-off value of albumin for predicting a prolonged length of ICU stay (≥10 days) in ARDS patients was <3.25 g/dL with AUC 0.623, p<0.05, sensitivity of 86.67%, specificity of 45.45%, and 95% confidence interval (CI) [0.513–0.732], and on multivariate analysis it increased the odds of prolonged ICU stay by 8.9 times (Hosmer and Lemeshow p value 0.810, 95% CI [2.760–28.72]). …”
Get full text

NON-FUNCTIONING SPORADIC PANCREATIC NEUROENDOCRINE TUMOR IS AN INDEPENDENT RISK FACTOR FOR RECURRENCE AFTER SURGICAL TREATMENT by Estela Regina Ramos Figueira, André Luis Montagnini, Jessica Okubo, Ana Gabriela Vivarelli Fernandes, Marina Alessandra Pereira, Ulysses Ribeiro Junior, Paulo Herman, José Jukemura

“…In univariate analysis, age, tumor type, tumor size, and TNM staging were identified as potential risk factors for tumor recurrence. In multivariate analysis, only the NF-PNET type was identified as an independent prognostic factor for disease recurrence. …”
Get full text

Prevalence of adherence and its impact on quality of life in oral anticoagulant users in Egypt: A cross-sectional study from two Egyptian university hospitals by Mohamed Terra, Amro Badr, Mohamed Baklola, Ibrahim Hegazy, Muhammed Elmanzlawey, Islam Elrakhawy, Ahmed Muhammed

“…Educational level, initially significant, did not persist as a predictor in multivariate analysis. Targeted strategies are needed to improve adherence and patient outcomes.…”
Get full text

Determination of Flavanones in Orange Juices Obtained from Different Sources by HPLC/DAD by Lidércia C. R. Cerqueira e Silva, Jorge M. David, Rafael dos S. Q. Borges, Sérgio L. C. Ferreira, Juceni P. David, Pedro S. dos Reis, Roy E. Bruns

“…The results were also evaluated using the principal component analysis (PCA) multivariate analysis technique which showed that poncirin, naringenin, and naringin were the principal elements that contributed to the variability in the sample concentrations.…”
Get full text

Bryophytes as Indicators of Disturbance in One of the Last Remnants of the Mountain Forests of El Oro Province, Ecuador by Ángel Benítez, Richard Nagua, Jefferson Medina, Gregorio Lapo, Erika Yangua-Solano, Rolando Andrade-Hidalgo

“…Changes in species richness and diversity were analyzed using generalized linear models (GLMs), and changes in species composition, using multivariate analysis. A total of 57 bryophyte species (36 liverworts and 21 mosses) were recorded in trunk bases. …”
Get full text

Four-Year Outcomes of Left Main Percutaneous Coronary Intervention with a Bioresorbable Scaffold in the Circumflex Ostium by Andrejs Erglis, Inga Narbute, Dace Sondore, Sanda Jegere, Indulis Kumsars, Andis Dombrovskis, Karlis Grikis, Ieva Briede, Kristine Dombrovska, Karlis Trusinskis, Alona Grave, Martins Erglis, Martins Kalejs, Peteris Stradins, Uldis Strazdins

“…Univariate predictors of the 4-year outcome were higher LDL cholesterol and BVS size ≤2.5 mm. On multivariate analysis, LCX lesion preparation with a cutting balloon and post-procedure use of intravascular ultrasound for optimization were found to be independent protective factors of MACE. …”
Get full text

Prevalence of Depressive Symptoms and Associated Factors among HIV-Positive Youth Attending ART Follow-Up in Addis Ababa, Ethiopia by Helina Abebe, Shegaye Shumet, Zebiba Nassir, Melkamu Agidew, Dessie Abebaw

“…Prevalence of depressive symptoms among HIV-positive youth was 35.5% (95% CI:31.3, 39.6). In multivariate analysis, age range between 20 and 24 years with (AOR=2.22, 95% CI: 1.33,3.62), history of opportunistic infection (AOR=1.94, 95% CI:1.15,3.27), poor medication adherence (AOR=1.73, 95%CI:1.13,2.64, low social support (AOR=2.74, 95%CI:1.13,2.64), moderate social support (AOR=1.75 95% CI: 1.03,2.98), and stigma (AOR=2.06, 95% CI: 1.35,3.14) were associated with depressive symptoms. …”
Get full text

Clinical significance of PCT, CRP, IL-6, NLR, and TyG Index in early diagnosis and severity assessment of acute pancreatitis: A retrospective analysis by Xu Xinyu, Zhou Jiang, Ai Qing, Li Lihua, Liu Xiehong, Zhou Lin

“…Alcohol consumption and hyperlipidemia were significantly linked to AP severity (P for trend < 0.0001). Multivariate analysis identified hyperlipidemia (OR = 3.030, P = 0.040), CRP (OR = 1.011, P < 0.001), and NLR (OR = 1.078, P = 0.020) as independent SAP predictors. …”
Get full text

Clinical outcomes of intravenous urography-assisted shockwave lithotripsy for radiolucent ureteral stones by Shinya Somiya, Shigeki Koterazawa, Katsuhiro Ito, Takao Haitani, Yuki Makino, Ryuichiro Arakaki, Norio Kawase, Yoshihito Higashi, Hitoshi Yamada, Toru Kanno

“…The primary outcome was a stone-free rate with one session within 30 days, defined as no residual stones without auxiliary treatment. The multivariate analysis was used to examine whether the intravenous urography use predicted treatment success. …”
Get full text