Revisiting Hemicraniectomy: Late Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Stroke and the Role of Infarct Growth Rate by Saadat Kamran, Naveed Akhtar, Abdul Salam, Ayman Alboudi, Kainat Kamran, Arsalan Ahmed, Rabia A. Khan, Mohsin K. Mirza, Jihad Inshasi, Ashfaq Shuaib

“…Functional outcome analyzed as mRS 0–4 versus mRS 5-6 showed no difference in this split between early and late operated on patients [P=0.140] and mortality [P=0.975]. Multivariate analysis showed that age ≥ 55 years, MCA with additional infarction, septum pellucidum deviation ≥1 cm, and uncal herniation were independent predictors of poor functional outcome at three months. …”
Get full text

Colonic strictures in Crohn’s disease: a non-surgical survival by Sarra Laabidi, Hamed Aboubecrine, Salma Souissi, Donia Gouiaa, Asma Labidi, Nadia Ben Mustapha, Anis Haddad, Amine Sebai, Meriem Serghini, Monia Fekih, Hanene Jaziri, Jalel Boubaker

“…Complications such as collections or internal fistulas (p = 0.03), parietal ulceration on imaging (p = 0.01), and acute intestinal obstruction (p = 0.01) were associated with reduced surgery-free survival. In multivariate analysis, biologic therapy was the only independent protective factor against surgery (p = 0.001, OR = 0.19).Conclusion The early introduction of biologic therapy is crucial for increasing surgery-free survival in patients with colonic stenosis in CD, given the limited effectiveness of conventional treatments.…”
Get full text

A nomogram for predicting prognosis for young cervical neuroendocrine carcinoma: A SEER-based study and external validation by Ning Xie, Haijuan Yu, Jie Lin, Sufang Deng, Linying Liu, Yang Sun

“…Finally, a simplified scoring system for clinical use was constructed by dividing patients into high-risk and low-risk groups.ResultsPathological type, FIGO stage, and surgery were independent risk factors by univariate and multivariate analysis (P < 0.05). The prognostic nomogram consisting of the above three independent risk factors had high accuracy. …”
Get full text

Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma by Heike Loeser, Max Kraemer, Florian Gebauer, Christiane Bruns, Wolfgang Schröder, Thomas Zander, Hakan Alakus, Arnulf Hoelscher, Reinhard Buettner, Philipp Lohneis, Alexander Quaas

“…We found a strong positive correlation of IDO-positive TILs, CD3-positive T lymphocytes, and INF-γ mRNA-producing TILs in the tumor microenvironment of EACs showing significantly better overall survival (47.7 vs. 22.7 months, p<0.001) with emphasis on early tumor stages (pT1/2: 142.1 vs. 37.1 months, p<0.001). In multivariate analysis, IDO is identified as an independent prognostic marker. …”
Get full text

The Risk Factors of Self-Management Behavior among Chinese Stroke Patients by Huang Shuqi, Li Siqin, Wu Xiaoyan, Yang Rong, Zhao Lihong

“…The score of self-management among Chinese stroke patients was 151.07 ± 18.53. Multivariate analysis showed that the way of paying medical expenses (OR = 3.215, 95% CI (1.130, 7.769)), self-management efficacy (OR = 2.467, 95% CI (1.534, 3.968)), health education before discharge (OR = 2.354, 95% CI (1.457, 3.802)), age (elder) (OR = 2.060, 95% CI (1.265, 3.355)), educational level (OR = 1.869, 95% CI (1.169, 2.988)), and mRS score (OR = 1.850, 95% CI (1.129, 3.031)) were statistically significant (P < 0.05). …”
Get full text

Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation in relation to the Patients’ Age: Results from a Large Real-World Multicenter Observational Project by Luigi Sciarra, Saverio Iacopino, Giuseppe Arena, Claudio Tondo, Paolo Pieragnoli, Giulio Molon, Massimiliano Manfrin, Antonio Curnis, Antonio Dello Russo, Giovanni Rovaris, Giuseppe Stabile, Leonardo Calò, Gabriele Boscolo, Roberto Verlato

“…In the univariate and multivariate analysis, age did not result in a significant predictor of AF recurrence during follow-up; however, a trend toward higher AF recurrences rates in patients ≥67 years was observed. …”
Get full text

Prevalence and correlates of facemask usage during the second wave of COVID-19 pandemic in Uganda. by Nelson Onira Alema, Christopher Okot, Emmanuel Olal, Eric Nzirakaindi Ikoona, Freddy Wathum Drinkwater Oyat, Steven Baguma, Denish Omoya Ochula, Patrick Odong Olwedo, Johnson Nyeko Oloya, Francis Pebalo Pebolo, Pamela Okot Atim, Godfrey Smart Okot, Ritah Nantale, Judith Aloyo, David Lagoro Kitara

“…The reported prevalence of facemask wearing in public among respondents was high [88.7%,95%CI:86%,-91%]. A multivariate analysis found that obese respondents and those who were receptive (agreed) to the lockdown measures were respectively,1.12 times more likely to wear facemasks [aPR = 1.12,95%CI:1.04-1.19;p < 0.01], and1.23 times more likely to wear facemasks [aPR = 1.23, 95%CI:1.07-1.41;p < 0.01]. …”
Get full text

Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA by Ming-Chin Lan, Stanley Yung-Chuan Liu, Ming-Ying Lan, Yun-Chen Huang, Tung-Tsun Huang, Yen-Bin Hsu

“…Results Univariate analysis revealed that non-positional dependency was correlated with a higher BMI (p < 0.001), neck circumference (p < 0.001), modified Mallampati score (p = 0.003), AHI (p < 0.001), degree of velum concentric collapse (p = 0.004), degree of oropharyngeal lateral wall collapse (p < 0.001), and degree of tongue base anteroposterior collapse (p = 0.004). Multivariate analysis revealed that oropharyngeal lateral wall collapse (OR = 1.90, p = 0.027) was the only anatomical factor significantly predicted non-positional dependency in OSA patients. …”
Get full text

Derivation of Sa-MoDEI score from DEI. Tak for prognostication in Buerger's Disease - Preliminary data of a prospective observational cohort by Gregory Pathrose, Albert A Kota, Prabhu Premkumar, Prasanna Samuel, Shivraj Padiyar, Deepak Selvaraj, Prasanta Padhan, Debashish Danda

“…Independent factors associated with bad outcome on multivariate analysis were age of onset below 39 years (Hazard Ratio [HR] = 6.00, 95% confidence interval [CI] (1.35–26.67), P = 0.019) and Sa-MoDEI score above 8 (HR = 9.77, 95% CI (2.60–36.71), P = 0.001). …”
Get full text

Association of Metabolic Syndrome or Weather Conditions with the Severity and Prognosis of Sudden Sensorineural Hearing Loss by Yixi Xu, Yao Zhang, Qi Yan, Chen Chen, Bin Zhu, Ying Wang

“…According to the multivariate analysis, MetS was significantly associated with a poorer prognosis of SSNHL; a high ambient temperature difference at onset and hypertension were correlated with a poor prognosis. …”
Get full text

Serum Albumin Is Independently Associated with Persistent Organ Failure in Acute Pancreatitis by Wandong Hong, Suhan Lin, Maddalena Zippi, Wujun Geng, Simon Stock, Zarrin Basharat, Bicheng Cheng, Jingye Pan, Mengtao Zhou

“…Decreased albumin levels were also proportionally associated with prolonged hospital stay (Ptrend<0.001) and the risk of death (Ptrend<0.001). Multivariate analysis suggested that biliary etiology, chronic concomitant diseases, hematocrit, blood urea nitrogen, and the serum albumin level were independently associated with persistent organ failure. …”
Get full text

10 Fr S-Type Plastic Pancreatic Stents in Chronic Pancreatitis Are Effective for the Treatment of Pancreatic Duct Strictures and Pancreatic Stones by Ken Ito, Naoki Okano, Seiichi Hara, Kensuke Takuma, Kensuke Yoshimoto, Susumu Iwasaki, Yui Kishimoto, Yoshinori Igarashi

“…During the follow-up period, pancreatic cancer developed in three patients (5.1%). Multivariate analysis revealed that the presence of remnant stones after stenting treatment was significantly associated with a higher rate of main pancreatic duct restenosis (p=0.03). …”
Get full text

Prior Appendectomy and the Onset and Course of Crohn’s Disease in Chinese Patients by Dafan Chen, Jing Ma, Qiwen Ben, Lungen Lu, Xinjian Wan

“…Appendectomy was a risk factor for the onset of CD independent of smoking in the multivariate analysis (OR: 1.878; 95% CI: 1.111–3.174; P=0.019). …”
Get full text

Diagnosis and clinical significance of prostate calcification using computed tomography by Seong Cheol Kim, Tae Young Lee, Woocheol Kang, Hoyoung Bae, Ji Hyung Yoon, Sungchan Park, Kyung Hyun Moon, Sang Hyeon Cheon, Taekmin Kwon

“…Only a small number of calcifications were observed in the peripheral zone (0.9%). Multivariate analysis revealed that both age and prostate calcification were significant predictors of urinary symptoms. …”
Get full text

Influence of Nursing Time and Staffing on Medication Errors: A Cross-Sectional Analysis of Administrative Data by Mutsuko Moriwaki, Michiko Tanaka, Masayuki Kakehashi, Masato Koizumi, Hiromasa Horiguchi, Kenshi Hayashida

“…Data for 27,629 ward days with 88,475 patients were analyzed. Multivariate analysis was performed to determine the impact of factors on medication errors. …”
Get full text

Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors by Lorena R. S. Almeida, Guilherme T. Valença, Nádja N. Negreiros, Elen B. Pinto, Jamary Oliveira-Filho

“…The prevalence of recurrent falls was 30% (95% CI 24%–38%). In multivariate analysis, independent risk factors for recurrent falls were (P<0.05) levodopa equivalent dose (OR = 1.283 per 100 mg increase; 95% CI = 1.092–1.507), UPDRS-ADL > 16 points (OR = 10.0; 95% CI = 3.6–28.3), FES-I > 30 points (OR = 6.0; 95% CI = 1.6–22.6), and Berg ≤ 48 points (OR = 3.9; 95% CI = 1.2–12.7).We encourage the utilization of these modifiable risk factors in the screening of fall risk.…”
Get full text

Demographic disparities in unimproved drinking water and sanitation in Ghana: a nationally representative cross-sectional study by Felix Boakye Oppong, Divine Darlington Logo, Dennis Boateng, Ephraim Kumi Senkyire

“…Open defecation was practised by 15.2% of Ghanaian households, with a prevalence of 58.8%, 6.7% and 12.5% in the Northern, Middle and Coastal zones, respectively. In the multivariate analysis, rural households (p&lt;0.001), households with more than five members (p&lt;0.001), households with heads less than 25 years (p=0.018), male-headed households (p&lt;0.001) and household heads with no/low level of education (p&lt;0.001) were significantly associated with drinking unimproved water. …”
Get full text

Prognostic Utility of the Combination of Platelet Count with Neutrophil-to-Lymphocyte Ratio in Aged Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Inter... by Xiao-Qing Quan, Hong-Yan Ji, Jie Jiang, Jia-Bao Huang, Cun-Tai Zhang

“…The Kaplan–Meier analysis showed that the combination of high platelet count and high neutrophil-to-lymphocyte ratio had a greater risk of death in short- and long-term endpoints (log-rank p=0.046, p<0.001, respectively). Moreover, by multivariate analysis, both high platelet count and high neutrophil-to-lymphocyte ratio groups were an independent predictor (hazard ratio: 2.132, 95% confidence interval: 1.020–4.454, p=0.044) and long-term mortality (hazard ratio: 2.791, 95% confidence interval: 1.406–5.538, p=0.003). …”
Get full text

To do or not to do? – Endometrial biopsy in younger women with abnormal uterine bleeding by Sandra Lynn Jaya-Bodestyne, Marlene Samantha Goh, Madeline Chan Hiu Gwan, Sonali Prashant Chonkar, Khurshid Merchant, Manisha Mathur

“…The data analysis included demographics, investigations undertaken, ultrasound findings, biopsy results, and treatment. Multivariable analysis was performed using modified Poisson regression models to compare women with endometrial hyperplasia (EH) (with or without atypia) and endometrial cancer (EC), to those with benign pathology, to identify risk factors for endometrial pathology. …”
Get full text

Assessment of correlation of fatigue in patients of rheumatoid arthritis using bristol rheumatoid arthritis fatigue multidimensional questionnaire score with disease activity – An... by Harpreet Singh, Kusum Yadav, Ritu Sangwan

“…There was a positive significant correlation (P value < 0.001) between BRAF-MDQ score and DAS-28 score (r = 0.503; 0.687 and 0.680) and CDAI score (r = 0.642,0.728 and 0.732) at baseline, 1 month, and 3 months, respectively. Multivariate analysis showed that CDAI (M0) was a significant factor affecting BRAF-MOQ score at follow-up of 3 months (M3) with beta coefficient of 0.872, P < 0.0001. …”
Get full text