Preliminary evidence of immune infiltration and neutrophil degranulation in peripheral blood of non-obese OSA patients related to cognitive decline by Qingqing Liu, Yanru Ou, Ting Liu, Yuming He, Xiangming Quan, Ruoyun Ouyang, Zhihui Shi

“…OSA patients showed a significant decline in overall cognitive function and were associated with higher daytime sleepiness scores. Multiple signaling pathways were enriched in the non-obese OSA cohort, including upregulation of neutrophil-degranulation. …”
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EFECTO DEL RECUENTO DE CÉLULAS SOMÁTICAS SOBRE LA APTITUD QUESERA DE LA LECHE Y LA CALIDAD FISICOQUÍMICA Y SENSORIAL DEL QUESO CAMPESINO by J. A. Vásquez, C. F. Novoa, J. E. Carulla

“…Las variables de aptitud quesera fueron analizadas por regresión múltiple y los resultados de la evaluación sensorial con la prueba no paramétrica de Friedman. …”
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Sources of PM2.5 Oxidative Potential during Haze and Non-haze Seasons in Chiang Mai, Thailand by Pitakchon Ponsawansong, Tippawan Prapamontol, Kittipan Rerkasem, Somporn Chantara, Kraichat Tantrakarnapa, Sawaeng Kawichai, Guoxing Li, Cao Fang, Xiaochuan Pan, Yanlin Zhang

“…Positive matrix factorization (PMF) indicated the biomass burning factor had the highest contribution (57.9%) to PM2.5 during haze episodes, followed by SIA (26.2%), and vehicle exhausts (7.8%). Furthermore, multiple linear regression (MLR) showed that biomass burning was the highest contributor to DTTv (43.0%). …”
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Comprehensive characterization of high-risk coding and non-coding single nucleotide polymorphisms of human CXCR4 gene. by Bonoshree Sarkar, Muhammad Safiul Alam Mondal, Taibur Rahman, Md Ismail Hosen, Atiqur Rahman

“…This receptor is essential for HIV infection as well as for many vital cellular processes and is implicated to be associated with multiple pathologies, including cancers. This study employs various computational tools to investigate the molecular effects of disease-vulnerable germ-line missense and non-coding SNPs of the CXCR4 gene. …”
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Association between Axial Length to Corneal Curvature Radius Ratio and Myopia in Adult Patients by Yanyun Fan, Yikeng Huang, Xionggao Huang

“…The association between AL and AL/CR of the eye and SE was analyzed by multiple linear regression. Also, the predictive ability of AL/CR for high myopia was investigated by ROC curve. …”
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Comparison of intensity normalization methods in prostate, brain, and breast cancer multi-parametric magnetic resonance imaging by Savannah R. Duenweg, Samuel A. Bobholz, Allison K. Lowman, Aleksandra Winiarz, Biprojit Nath, Michael J. Barrett, Fitzgerald Kyereme, Stephanie Vincent-Sheldon, Peter LaViolette

“…This study used MP-MRI collected from patients with confirmed prostate, brain, or breast cancer to examine common intensity normalization methods to identify which best harmonizes intensity values across cofounds.Materials and methodsMultiple normalization methods were deployed for intensity comparison between three unique sites, MR vendors, and magnetic field strength. …”
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Factors influencing access, quality and utilisation of primary healthcare for patients living with hypertension in West Africa: a scoping review by Tolib Mirzoev, Pablo Perel, Irene Akua Agyepong, Evelyn K Ansah, Kezia Naa Amerley Akosua Amarteyfio, Eugene Paa Kofi Bondzie, Veronika Reichenberger, Nana Efua Enyimayew Afun, Albert Kofi Mensah Cofie, Mary Pomaa Agyekum, Paul Lamptey

“…These factors are interconnected and complex and should be addressed as a whole to reduce the burden of hypertension in West Africa.Conclusion Multiple complex and interrelated factors at contextual, health systems, community and patient levels act as barriers and enablers to access, utilisation and quality of primary care for hypertension in West Africa. …”
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Timely short-term specialised palliative home care for older people with frailty and their family: a mixed-methods pilot randomised controlled trial and process evaluation by Lieve Van den Block, Kim de Nooijer, Lara Pivodic, Peter Pype, Nele Van Den Noortgate, Rose Miranda, Kim Eecloo, Stefanie De Buyser, Aurelie Joos, Katlijn Van Mulders

“…The baseline mean score on the five palliative care symptoms was 6.0 and 5.6 in intervention and control group, respectively; and 4.5 and 4.1 at 8 weeks (adjusted ratio 1.0, ie, no effects on symptoms).Conclusions While Frailty+ was generally welcomed by older people with frailty, families and palliative care nurses, our process evaluation uncovered multiple barriers, mostly rooted in the current organisation of specialised palliative care that is tailored to advanced stages of illness. …”
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CST2 promotes cell proliferation and regulates cell cycle by activating Wnt-β-catenin signalling pathway in serous ovarian cancer by Xiaohua Wang, Sufen Zhao, Yanwei Guo, Chunhui Wang, Shuyu Han, Xingcha Wang

“…Background Cystatin SA (CST2) plays multiple roles in different types of malignant tumours; however, its role in serous ovarian cancer (SOC) remains unclear. …”
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Development of improved deep learning models for multi-step ahead forecasting of daily river water temperature by Mehdi Gheisari, Jana Shafi, Saeed Kosari, Samaneh Amanabadi, Saeid Mehdizadeh, Christian Fernandez Campusano, Hemn Barzan Abdalla

“…These models integrate ensemble empirical mode decomposition (EEMD) with machine learning techniques for forecasting WT across multiple time horizons (one, three, and five days). …”
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MHRA-MS-3D-ResNet-BiLSTM: A Multi-Head-Residual Attention-Based Multi-Stream Deep Learning Model for Soybean Yield Prediction in the U.S. Using Multi-Source Remote Sensing Data by Mahdiyeh Fathi, Reza Shah-Hosseini, Armin Moghimi, Hossein Arefi

“…These findings highlight the methodology’s capability to handle multiple RS data types and its role in improving yield predictions, which can be helpful for sustainable agriculture.…”
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β-Caryophyllene and Statins in Bone Fracture Healing – A Narrative Review by Marom H, Khan MA, Darvish N, Tornetta III P, Khoury A, Weil YA, Skelley NW, Allison DC, Meiron S, Ehrmann Barr T

“…Statins, known for their cholesterol-lowering effects, also promote bone formation and reduce bone resorption through multiple biochemical pathways. Both BCP and statins have shown promising results in preclinical studies, enhancing bone density and promoting fracture healing. …”
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Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers by Yuyun Zhong, Ruiqi Wang, Zijie Huang, Zhaoting Hu, Bin Peng, Bin Chen, Liyue Sun

“…Conclusions This study demonstrates that SETD4 is an immune‐oncogenic molecule in multiple cancers, with the potential to be a diagnosis, prognosis, and targeted therapy marker.…”
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Developing generic clinical trial animated explainer videos in the UK: results of a survey and case study by Clare Calvert, Vicki S. Barber, Duncan Appelbe, Kirsty Sprange, Claire Nollett, Fiona Lugg-Widger, Samantha Tanner, Duncan B. Richards

“…Via consensus survey across multiple stakeholders, we have determined a hierarchy of the importance of explaining these concepts. …”
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TAp63γ is the primary isoform of TP63 for tumor suppression but not development by Xinbin Chen, Wenqiang Sun, Xiangmudong Kong, Xin Ming, Yanhong Zhang, Wensheng Yan, Shakur Mohibi, Mingyi Chen, Keith Mitchell, Jin Zhang

“…Moreover, mice deficient in p63γ are prone to chronic inflammation in multiple organs and liver steatosis potentially via altered lipid metabolism. …”
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Determinants of Anemia among Pregnant Women at Public Hospitals in West Shewa, Central Ethiopia: A Case-Control Study by Berhanu Senbeta Deriba, Elias Teferi Bala, Gizachew Abdissa Bulto, Tinsae Abeya Geleta, Agumas Fentahun Ayalew, Addis Adera Gebru, Habtamu Oljira Desta, Mengistu Benayew Shiferaew, Lidya Zerihun Sahile

“…Descriptive statistics such as tables, graphs, and proportions were used to present the data. Binary and multiple logistic regression analyses were computed to identify the determinants of anemia. …”
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Clinical and neurological specifics of the vertebrogenic lumbosacral radiculopathy course in the patients with RS1143627 polymorphism of the <i>IL-1β</i> gene by Elena A. Statinova, Natalya V. Fominova, Maria S. Kishenya

“…In the study subjects of ≤ 41 years of age, the multiplicative model showed a higher risk of VLSRP with the minor T allele by 1.8-fold (OR 1.80; 95% CI 1.02–3.19). …”
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Computational network analysis of two popular skin cancers provides insights into the molecular mechanisms and reveals common therapeutic targets by Md Sujan Mahmud, Bikash Kumar Paul, Md. Rakibul Hasan, K.M. Tanjida Islam, Imran Mahmud, Shahin Mahmud

“…PDI network analysis identified ibuprofen as a potential therapeutic agent targeting PTGS2 and BCL2, while other proteins VDR, MMP2, MMP9, and TYR showed interactions with multiple drugs. This computational analysis provides valuable insights into the shared molecular mechanisms of BCC and AK, revealing common pathways and potential therapeutic targets for developing novel treatment strategies and repurposing existing drugs for these prevalent skin cancers. …”
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Cultural Adaptation of an Aboriginal and Torres Strait Islanders Maternal and Child mHealth Intervention: Protocol for a Co-Design and Adaptation Research Study by Sana Ishaque, Ola Ela, Chris Rissel, Karla Canuto, Kerry Hall, Niranjan Bidargaddi, Annette Briley, Claire T Roberts, Sarah Jane Perkes, Anna Dowling, Billie Bonevski

“…Participants will be recruited from multiple Aboriginal and/or Torres Strait Islander–specific health services under the local health networks around metropolitan South Australia. …”
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A Potential Protective Effect of Alcohol Consumption in Male Genital Lichen Sclerosus: A Case-Control Study by Joey El Khoury, Jessica Andraos, Anthony Kanbar, Rami Halabi, Serge Assaf, Anthony Mina, Sabine El Breidi, Charbel Dabal, Charbel El Hachem, Rodrigue Saad, Antoine Kassis, Maher Abdessater, Raghid El Khoury

“…In this study, we were able to compare multiple variables between 47 circumcised patients diagnosed with LSc and a control group. …”
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