Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol by Alison B Rushton, Nicola R Heneghan, Taweewat Wiangkham, Uchukarn Boonyapo, Piyameth Dilokthornsakul, Nattawan Phungwattanakul

“…A network of traditional pairwise meta-analysis allows comparisons of multiple interventions from both direct and indirect evidence to provide a hierarchal establishment for enhancing decision making of clinical practitioners.Ethics and dissemination Ethic approval is not required as the study is a literature review. …”
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Blue applicability grade index assessment and response surface modelling to synchronous determination of metformin hydrochloride, vildagliptin and dapagliflozin propanediol monohyd... by Pintu Prajapati, Krutika Patil, Dhrumi Naik, Veera Shakar Pulusu, Anzarul Haque, Mohd Abul Kalam, Shailesh Shah

“…The developed method was applied for synchronous assay of multiple combinations of metformin, vildagliptin and dapagliflozin using single chromatographic condition to save time, cost and resources for analysis. …”
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The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer by XiaoJun Duan, Rihan Wu, Mingyang Zhang, Kexin Li, Lei Yu, Huirong Sun, Xingxia Hao, Changshan Wang

“…In this study, the data originated from the Genotype-Tissue Expression (GTEx) and the Cancer Genome Atlas (TCGA) databases were input into multiple online bioinformatic tools to study the characteristics of NOTCH1 in pan-cancer. …”
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Recording of Falls in Elderly Fallers in Northern Greece and Evaluation of Aging Health-Related Factors and Environmental Safety Associated with Falls: A Cross-Sectional Study by Dimitrios Lytras, Evaggelos Sykaras, Paris Iakovidis, Konstantinos Kasimis, Ioannis Myrogiannis, Anastasios Kottaras

“…Severity of each fall event across a variety of locations was examined using the Kruskal-Wallis one-way analysis of variance. Multiple linear regression was applied to examine the effect of the mean values of functional tests and medical records on the number of fall events. …”
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Cesarean delivery in Nigeria: prevalence and associated factors―a population-based cross-sectional study by Asa Auta, Emmanuel O Adewuyi, Vishnu Khanal, Samson J Tapshak, Yun Zhao

“…Factors associated with increased odds of CS were urban residence (adjusted OR (AOR): 1.51, 95% CI 1.15 to 1.97), maternal age ≥35 years (AOR: 2.12, 95% CI 1.08 to 4.11), large birth size (AOR: 1.39, 95% CI 1.10 to 1.74) and multiple births (AOR: 4.96, 95% CI 2.84 to 8.62). Greater odds of CS were equally associated with maternal obesity (AOR: 3.16, 95% CI 2.30 to 4.32), Christianity (AOR: 2.06, 95% CI 1.58 to 2.68), birth order of one (AOR: 3.86, 95% CI 2.66 to 5.56), husband’s secondary/higher education level (AOR: 2.07, 95% CI 1.29 to 3.33), health insurance coverage (AOR: 2.01, 95% CI 1.37 to 2.95) and ≥4 antenatal visits (AOR: 2.84, 95% CI 1.56 to 5.17).Conclusions The prevalence of CS was low, indicating unmet needs in the use of caesarean delivery in Nigeria. …”
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Effect of delayed sea ice retreat on zooplankton communities in the Pacific Arctic Ocean: a generalized dissimilarity modeling approach by Yuya Hibino, Kohei Matsuno, Kohei Matsuno, Amane Fujiwara, Yoshiyuki Abe, Nanami Hosoda, Motoyo Itoh, Atsushi Yamaguchi, Atsushi Yamaguchi

“…Under significant warming scenarios (Shared Socioeconomic Pathway [SSP]1-2.6 and SSP5-8.5), GDM-based multiple effects predicted that the zooplankton communities in high latitudes will be more affected than those on the southern shelf (northern Bering Sea to southern Chukchi Sea). …”
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Study on the crack propagation morphology and initiation law of coal rock under the action of underwater electric pulse by XianKai Bao, Bin Jiang, GuangQin Cui, XiaoFan Zhang, Tong Zhang, Wu Zhang

“…When the impact load of the high-voltage electric pulse is small(3 MPa hydrostatic pressure, 7 kV discharge voltage), cracks crack symmetrically around the drilling hole, and when the impact load is large(3 MPa hydrostatic pressure, 13 kV discharge voltage), most of the cracks inside the specimen crack symmetrically along the radial or tangential wings of the drilling hole, and the cracks change from multiple pairs of double-wing cracks to a pair of double-wing cracks with the weakening of the shock wave energy until only one single wing crack remains. …”
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Metagenomic analysis of DNA viruses from posttransplant lymphoproliferative disorders by Vikas R. Dharnidharka, Marianna B. Ruzinova, Chun‐Cheng Chen, Priyanka Parameswaran, Harry O'Gorman, Charles W. Goss, Hongjie Gu, Gregory A. Storch, Kristine Wylie

“…In EBV‐positive PTLD, EBNA‐LP, EBNA1 and EBNA3C had significantly higher levels of nonsynonymous gene variants compared to the other EBV genes. Multiple viruses are detectable in PTLD tissues by MSS. …”
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The bioinfomatics analysis of the M1 macrophage-related gene CXCL9 signature in cervical cancer by Wenxin Liao, Tingting Liu, Yang Li, Hua Liang, Juexiao Deng, Fujin Shen

“…Then we constructed the protein–protein interaction networks by STRING database and performed functional enrichment analysis to investigate the biological effects of the coexpression genes. Next, we used multiple bioinformatics databases and experiments to overall investigate coexpression gene CXCL9, including western blot assay and immunohistochemistry assay, GeneMANIA, Kaplan-Meier Plotter, Xenashiny, TISCH2, ACLBI, HPA, TISIDB, GSCA and cBioPortal databases.Results There were 77 positive coexpression genes and 5 negative coexpression genes in M1 macrophage. …”
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A Review of Needle Navigation Technologies in Minimally Invasive Cardiovascular Surgeries—Toward a More Effective and Easy-to-Apply Process by Katharina Steeg, Gabriele Anja Krombach, Michael Horst Friebe

“…For instance, fusion technologies overlay information from multiple visual approaches within a single interface to overcome individual limitations. …”
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Potential alternative and novel biomarkers for paediatric MAFLD: exploratory evidence from a Chinese cohort by Fan Yang, Mengyuan Hu, Lulian Xu, Xiaowei Zheng, Lihong Zhu, Le Zhang, Haoyang Zhang

“…Abstract Background While the associations between pediatric non-obese metabolic dysfunction-associated fatty liver disease (MAFLD) and multiple diagnostic biomarkers are well-established, the role of a broader range of blood-based, urine-based, and body composition-based biomarkers for monitoring MAFLD are needed. …”
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Evaluating handgrip strength and functional tests as indicators of gait speed in older females by Valentina Muollo, Samuel D’Emanuele, Laura Ghiotto, Doriana Rudi, Federico Schena, Cantor Tarperi

“…Pearson's correlation (r) was used to assess the strength of associations between HGS and functional variables, while multiple linear regression models identified determinants of GS. …”
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Strength training for osteoporosis prevention during early menopause (STOP-EM): a pilot study protocol for a single centre randomised waitlisted control trial in Canada by Leigh Gabel, Lauren A Burt, Christina J Alexander, Leah Kaluta, Patrick W Whitman, Emma O Billington

“…Feasibility will be assessed based on a priori criterion for success and secondary outcomes will be assessed via multiple linear regressions. The study will be considered feasible if>50% of interested and eligible participants are recruited, if there is>60% adherence to the two times per week, 9-month exercise intervention and if at least 65% of the sample complete the final study visit. …”
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Increasing Quantity and Internal Quality of Japanese Quail (Coturnix coturnix japonica) Eggs by Shooting Laser Puncture at Reproductive Acupuncture Points by Sunaryo Hadi Warsito, Tatang Santanu Adikara, Septiana Megasari, Ilham Radifan Pratama, Mirni Lamid, Herry Agoes Hermadi

“…Then, the research results were analyzed using Analysis of Variance and followed by Duncan’s Multiple Range Test. Laser puncture shooting at the reproductive acupuncture point of Japanese quail (Coturnix coturnix japonica) can increase the quantity of eggs (p<0.05). …”
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Poor COVID-19 Preventive Practice among Healthcare Workers in Northwest Ethiopia, 2020 by Belayneh Ayanaw Kassie, Aynishet Adane, Eskeziaw Abebe Kassahun, Amare Simegn Ayele, Aysheshim Kassahun Belew

“…Overall compliance towards COVID-19 preventive practice among healthcare workers was found to be low. Multiple education and training platforms with focus on COVID-19 preventive measures and adequate personal protective equipment and supplies should be provided for healthcare providers.…”
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RET Inhibitor SPP86 Triggers Apoptosis and Activates the DNA Damage Response Through the Suppression of Autophagy and the PI3K/AKT Signaling Pathway in Melanoma Cells by Zhang Y, Liu H, Wang K, Zheng J, Luan H, Xin M

“…Concurrently, the underlying mechanisms, including the PI3K/AKT signaling pathway and autophagy modulation, were also elucidated.Results: The study demonstrated that SPP86 exerts anti-tumor effects in melanoma cells through multiple mechanisms: it induces apoptosis, causes DNA damage, inhibits cell proliferation, and suppresses the PI3K/AKT signaling pathway. …”
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Machine learning algorithms in constructing prediction models for assisted reproductive technology (ART) related live birth outcomes by Junwei Peng, Xiaoyujie Geng, Yiyue Zhao, Zhijin Hou, Xin Tian, Xinyi Liu, Yuanyuan Xiao, Yang Liu

“…We conducted a retrospective study by using a database includes a total of 11,938 couples who underwent in vitro fertilization (IVF) treatment between January 2015 and December 2022 in a medical institution of southwest China Yunnan province. Multiple candidate predictors were screened out by using the importance scores. …”
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A Clinical Prediction Model for Pathologic Upgrade to Invasive Carcinoma Following Conization of Cervical High‐Grade Squamous Intraepithelial Lesions by Qiao Liu, Jing Yang, Hui Cheng, Chuqiang Shu, Yi Tang, Jing Zhao

“…Conclusion We developed and validated a nomogram incorporating multiple clinically relevant variables to better identify cases of HSIL progressing to early cervical cancer, providing a basis for individualized treatment and surgical approach selection.…”
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Systematic review of reviews on interventions to engage men and boys as clients, partners and agents of change for improved sexual and reproductive health and rights by Sanyukta Mathur, Julie Pulerwitz, Ann Gottert, Jesse Werner, Renay Weiner, Chantalle Okondo, Sarah Magni

“…We conducted a review of the effectiveness of interventions to engage men and boys across SRHR domains, lessons learnt about successful programming, and about harms/unintended consequences, in low- and middle-income countries (LMIC).Design Systematic review of reviews following Cochrane guidelines.Data sources PubMed, Cumulative Index to Nursing and Allied Health Literature, Web of Science and Cochrane were searched (18 October–9 November 2022; 9 September 2024).Eligibility criteria Eligible reviews were published since 2015, covered WHO-defined SRHR domain(s) and focused mostly on LMIC.Data extraction and synthesis Data extraction by multiple reviewers focused on intervention effectiveness, implementation best practices, unintended consequences, and quality/risk of bias.Results Thirty-five systematic reviews were included, comprising ~960 primary studies. …”
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Complications after autologous fat grafted into residual capsular sac after removal of breast prosthesis: Case reports by Ting Li, Yi Sun, Sufan Wu, Ce Zhang

“…In a word, while performing the procedure of breast prosthesis removal, it is imperative to thoroughly excise the capsular sac to prevent the creation of residual capsular sac; Autologous fat should be inserted in multiple directions and correct layers. Prior to surgery, thorough preoperative positioning examinations should be conducted to avert the inadvertent injection of autologous fat.…”
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