Causal relationship between immune cells and risk of heart failure: evidence from a Mendelian randomization study by Wenjing Cao, Zefu Yang, Liumei Mo, Zhenhao Liu, Jiawei Wang, Zhenhong Zhang, Kui Wang, Wei Pan

“…Sensitivity analyses were conducted to validate the strength and reliability of the MR findings.ConclusionsOur study suggests that there appears to be a causal effect between multiple immune cells on heart failure. This discovery provides a new avenue for the development of therapeutic treatments for HF and a new target for drug development.…”
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Study of Health-Related Quality of Life and Healthcare Utilization among Type 2 Diabetic Population in an Urban Area of Eastern Nepal by Sangita Shah, Nilambar Jha, Deepak Kumar Yadav, Prajjwal Pyakurel, Sanjib Kumar Sharma, Suman Bahadur Singh

“…Five wards were selected by systematic random sampling, and the population was proportionate according to the sample size. Multiple linear regressions were conducted to identify the factors associated with quality of life and its domains. …”
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The use of strong analgesics for prehospital pain management in children in the region of Southern Denmark: a register-based study by Josefine Tvede Colding-Jørgensen, Gina Maj Graven Brandstrup, Vibe Maria Laden Nielsen, Josefine Gradman, Line Anker Bang Thybo, Peter Martin Hansen, Daniel Wittrock, Stig Nikolaj Fasmer Blomberg, Helle Collatz Christensen, Søren Mikkelsen

“…Abstract Background Acute pain in the prehospital setting is frequent and prehospital pain management presents multiple challenges, especially in children. There is a lack of high-level evidence regarding prehospital pain management in the paediatric population worldwide. …”
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Chromatin environment-dependent effects of DOT1L on gene expression in male germ cells by Manon Coulée, Alberto de la Iglesia, Mélina Blanco, Clara Gobé, Clémentine Lapoujade, Côme Ialy-Radio, Lucia Alvarez-Gonzalez, Guillaume Meurice, Aurora Ruiz-Herrera, Pierre Fouchet, Julie Cocquet, Laïla El Khattabi

“…Abstract The H3K79 methyltransferase DOT1L is essential for multiple aspects of mammalian development where it has been shown to regulate gene expression. …”
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Learning and Teaching Geological Field Skills in a Virtual World: Insights From an Undergraduate Virtual Fieldtrip in Kinlochleven, Scotland by Matthew J. Genge, Valentin Laurent, Philippa J. Mason, Alan R. T. Spencer, Mark D. Sutton, Alex C. Whittaker

“…A major limitation of the virtual fieldtrip was in the development of skills requiring spatial visualisation, in particular, the spatial association of features across multiple scales. The virtual fieldtrip had benefits for inclusivity, making fieldwork more accessible than its outdoor equivalent. …”
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Flexible reproductive seasonality in Africa-dwelling papionins is associated with low environmental productivity and high climatic unpredictability by Dezeure, Jules, Dagorrette, Julie, Burtschell, Lugdiwine, Chowdhury, Shahrina, Lukas, Dieter, Swedell, Larissa, Huchard, Elise

“…Our results demonstrate wide variation in the intensity of birth seasonality between and within species. Across multiple measures of climatic variation, we found rainfall unpredictability to be the only clear predictor of the intensity of reproductive seasonality across populations, i.e., greater year-to-year variation in the amount of rainfall was associated with lower to no reproductive seasonality. …”
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Spatial Downscaling of GPM Annual and Monthly Precipitation Using Regression-Based Algorithms in a Mountainous Area by Chesheng Zhan, Jian Han, Shi Hu, Liangmeizi Liu, Yuxuan Dong

“…In this study, we investigated two downscaling algorithms based on the Multiple Linear Regression (MLR) and the Geographically Weighted Regression (GWR), respectively. …”
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Application of the AHP and PROMETHEE II individual decision-making methods and the Condorcet group decision-making method in the Selection of a multipurpose armored wheeled combat... by Miša D. Živković, Darko I. Božanić, Milija M. Suknović, Boris V. Delibašić

“…Conclusion: Solving the problem involves taking into account the views of military experts regarding the optimization of multiple criteria to provide the best performance vehicle suitable for use in various missions. …”
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Comparison of BCG Tokyo172 Strain Induction Therapy Between Low Dose and Standard Dose for Non-Muscle Invasive Bladder Cancer: Intravesical Instillation of BCG Tokyo172 Strain by Hideyuki Isobe, Fumitaka Shimizu, Takeshi Ieda, So Nakamura, Naoko Takazawa, Hanna Suetsugu, Kazunori Kajino, Shu Hirai, Hisashi Hirano, Katsuhito Yuzawa, Shigeo Horie

“…However, younger patients had significantly lower recurrence rates with standard-dose BCG compared to low-dose BCG. Multiple Cox regression analysis confirmed that older age, low-dose BCG, greater than three tumors, and a history of recurrence were significant predictors of recurrence. …”
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Providing medically tailored groceries and food resource coaching through the charitable food system to patients of a safety-net clinic in Dallas, Texas: a randomised controlled tr... by Michael Bowen, Sandi L Pruitt, Jaclyn Albin, Tammy Leonard, Willis Wong, Milette Siler, Carolyn Haskins, Jessica Turcios, Carla Pezzia, Alisha Ford, Bianca Schinzer, Kelseanna Hollis-Hansen

“…Analyses will include multiple regression models to analyse changes from baseline to follow-up as well as changes between groups over time. …”
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WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus aureus for Lysosomal Degradation by Mario Mauthe, Wenqi Yu, Oleg Krut, Martin Krönke, Friedrich Götz, Horst Robenek, Tassula Proikas-Cezanne

“…By confocal and electron microscopy we provide evidence that single- and multiple-Staphylococci entrapped undergo cell division. …”
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MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…Abstract Epithelial‒mesenchymal transition (EMT) is a process in which polar epithelial cells transform into active mesenchymal cells and acquire invasion and migration capabilities (Cano CE, Motoo Y, Iovanna JL in Sci World J 10, 2010). EMT is involved in multiple physiological and pathological processes in the human body. …”
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Arbuscular mycorrhizal fungi mitigate cadmium stress in maize by Qiqiang Kuang, Yujie Wu, Yamin Gao, Tingting An, Shuo Liu, Liyan Liang, Bingcheng Xu, Suiqi Zhang, Min Yu, Sergey Shabala, Yinglong Chen

“…Overall, AM symbiosis alleviated Cd toxicity in maize through multiple mechanisms, including enhanced photosynthesis, nutrient uptake, antioxidant defenses, and modulation of Cd transport and accumulation. …”
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Soil Surface Roughness in Temperate Forest During SMAPVEX19-22 by Victoria A. Walker, Michael H. Cosh, William A. White, Andreas Colliander, Victoria R. Kelly, Paul Siqueira

“…Data were collected across multiple forested domains during the Soil Moisture Active Passive Validation Experiment 2019–2022 to improve understanding of soil moisture retrievals under dense vegetation. …”
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Synchronous clonally related anaplastic large cell lymphoma and malignant histiocytosis by Mirvate Harb, Tom Abrassart, Laurent Dewispeleare, Pierre Sidon, Natacha Dirckx, Anne-laure Trepant, Julie Castiaux, Pierre Heimann, Jean-Francois Emile, Hussein Farhat

“…Patient died in the intensive care unit from a multiple-organ failure related to lymphohistiocytic hemophagocytosis. …”
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Sex steroid hormones mediate the association between neonicotinoids and obesity among children and adolescents by Qian Su, Jinzhu Luo, You Zhou, Miao Liu, Shaohua Zeng, Yin Li, Jieying Gao

“…The interaction effects of multiple neonicotinoids were determined by Chi-squared Automatic Interaction Detection method. …”
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Multi-spatial urban function modeling: A multi-modal deep network approach for transfer and multi-task learning by Zhaoya Gong, Chenglong Wang, Bin Liu, Binbo Li, Wei Tu, Yuting Chen, Zhicheng Deng, Pengjun Zhao

“…A range of data-driven models based on the representation learning of multiple data sources have focused on extracting spatially explicit characteristics at the feature level for urban function inference. …”
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Serum microRNAs as Diagnostic Markers in Polycystic Ovary Syndrome: A Narrative Review by K Lavanya, N Palaniappan, VM Vinodhini, Santhi Silambanan

“…Increased androgen production, recurrent anovulatory cycles and ovaries with multiple cysts are symptoms of this multiorgan endocrine condition. …”
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Medication burden in patients with dialysis-dependent CKD: a systematic review by Xuemei Liu, Ping Chen, Yun Liu, Xiaoyan Jia, Dongmei Xu

“…Data extraction and combining from multiple groups of number (n), mean, and standard deviation (SD) were performed using R programming language (version4.3.1; R Core Team, Vienna, Austria). …”
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Lucidin from <i>Rubia cordifolia</i> Outperforms FDA-Approved Lapatinib as a Potential Multitargeted Candidate for Breast Cancer Signalling Proteins by Akram Ahmed Aloqbi, Hadil Alahdal, Amany I. Alqosaibi, Mashael M. Alnamshan, Ibtesam S. Al-Dhuayan, Ahood A. Al-Eidan, Hind A. S. Alzahrani, Nouf K. ALaqeel, Fatmah Hazza Alsharif, Abeer Al Tuwaijri

“…<b>Results:</b> Lucidin demonstrated significant binding affinity and interaction potential with multiple breast cancer targets, outperforming Lapatinib in stability and binding interactions. …”
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