ENO1 promotes PDAC progression by inhibiting CD8+ T cell infiltration through upregulating PD-L1 expression via HIF-1α signaling by Aziguli Tulamaiti, Shu-Yu Xiao, Yan Yang, Musitaba Mutailifu, Xia-Qing Li, Shi-Qi Yin, Hong-Tai Ma, Hong-Fei Yao, Lin-Li Yao, Li-Peng Hu, Jun Li, Shu-Heng Jiang, Zhi-Gang Zhang, Yan-Miao Huo, Dong-Xue Li, Xue-Li Zhang

“…ENO1 was found to be overexpressed in multiple types of cancers. Here, we investigated the role of ENO1 in modulating the PDAC microenvironment.Using bioinformatic analyses, we demonstrated that ENO1 was highly expressed in PDAC patients, which was related to a poor prognosis. …”
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Altered expression of miRNA profile in peripheral blood mononuclear cells following the third dose of inactivated COVID-19 vaccine by Guanguan Qiu, Ruoyang Zhang, Huifeng Qian, Ruoqiong Huang, Jie Xia, Ruoxi Zang, Zhenkai Le, Qiang Shu, Jianguo Xu, Guoping Zheng, Jiangmei Wang

“…Bioinformatic analysis suggested that miR-25-5p, miR-34c-3p, and miR-206 may target multiple pathways involved in immune regulation and inflammation. …”
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Chemical Composition and Antimicrobial Activity of Essential Oil of <i>Camphora glanduliferum</i> ‘Honganzhang’ by Yang Yang, Qiuting Xiang, Yinan Yang, Donglv Shu, Jiawen Yan, Lijun Huang, Xiumei Yang, Jing Peng, Xingliang Chen, Guoqun Yang

“…Based on the main chemical components contained in <i>C. glanduliferum</i> ’Honganzhang’ and its remarkable antibacterial effect, this study is expected to provide a theoretical basis for the wide application of <i>C. glanduliferum</i> ’Honganzhang’ in multiple fields such as medicine, health care, food, and industry.…”
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Forecasting insect abundance using time series embedding and machine learning by Gabriel R. Palma, Rodrigo F. Mello, Wesley A.C. Godoy, Eduardo Engel, Douglas Lau, Charles Markham, Rafael A. Moral

“…However, another layer of complexity is added when other covariates are considered in the forecasting, such as climate time series collected along the monitoring system. Multiple combinations of climate time series and their lags can be used to build a forecasting method. …”
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Mortality and functional outcomes in elderly adults treated surgically by hemiarthroplasty for femoral neck fractures by Ankush Ratanpal, Katapadi Ramachandra Kamath, Preetham Raj V Salian, Saiprasad Sarvothama Baliga, Rajendra Annappa, Sayak Banerjee

“…Background: Despite multiple studies, less recent literature and data regarding the mortality associated with hip fractures in the elderly population are available. …”
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Pericardial Involvement in Hereditary Hemorrhagic Telangiectasia by Abir Derbel, Mouna Snoussi, Raida Ben Salah, Faten Frikha, Leila Abid, Imed Frikha, Sameh Marzouk, Zouhir Bahloul

“…Abdominal tomography showed multiple arterio-venous shunts of the liver. Liver involvement due to Rendu Osler Weber disease was retained. …”
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Association between higher mortgage payment-to-income ratio and greater psychological distress among high-income homeowners in Japan: A cross-sectional study by Kazuya Ogawa, Keiichi Shimatani, Ryotaro Iwayama, Norimichi Suzuki

“…We performed modified log Poisson regression analyses, incorporating income stratification, with missing data handled by multiple imputation. Results: For both overall respondents (PR = 1.22, 95 % CI 1.11–1.35) and the high-income group (PR = 1.23, 95 % CI 1.09–1.39), individuals with mortgage payment ratios ≥30 % were more likely to report psychological distress compared with those <30 %. …”
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Associations between intake of different types of vegetables and metabolic dysfunction-associated fatty liver disease: a population-based study by Chong Liu, Yubo Liu, Jie Liu, Jia Liu, Ting Lu, Jingjia Yu, Guogang Zhang, Kai Xu

“…Methods We investigated the associations between various types of vegetable consumption and the risk of MAFLD, utilizing data sourced from the National Health and Nutrition Examination Survey (NHANES) 2017–2018 cycle. Employing multiple logistic regression and subgroup analyses, we estimated odds ratios (ORs) and 95% confidence intervals (CIs). …”
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Monitoring Bone Healing: Integrating RF Sensing With AI by Ahmad Aldelemy, Ebenezer Adjei, Prince O. Siaw, Ali Al-Dulaimi, Viktor Doychinov, Nazar T. Ali, Rami Qahwaji, John G. Buckley, Pete Twigg, Raed A. Abd-Alhameed

“…Utilising MATLAB simulations, we created a comprehensive dataset enhanced with variations in bone diameter, muscle thickness, fat thickness, and hematoma size, augmented with multiple sensor configurations (two, four, six, and eight sensors). …”
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Exploring offshore wind’s potential to enhance energy security in nations with limited land and fuel resources by Kenji Shiraishi, Umed Paliwal, Nikit Abhyankar, Daniel M Kammen, Amol Phadke, Won Young Park

“…Each scenario incorporated three technology cost sensitivities and was assessed on multiple criteria including affordability, energy security, and land-use change. …”
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Complementary Non‐invasive Fish Monitoring Distinguishes Depth‐Dependent Fish Communities by Ewan Burns, Vijini Mallawaarachchi, Thomas M. Clarke, Belinda Martin, Joseph D. DiBattista, Jamie Hicks, Danny Brock, Elizabeth A. Dinsdale, Charlie Huveneers, Michael P. Doane

“…These findings emphasize the value of integrating multiple approaches for enhanced fish species detection, offering valuable insights into future biodiversity monitoring and conservation efforts.…”
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An open-label study evaluating the safety and efficacy of AMO-01 for the treatment of seizures in Phelan-McDermid syndrome by Tess Levy, J. Lloyd Holder, Jr., Joseph P. Horrigan, Michael F. Snape, Alison McMorn, Christina Layton, Hailey Silver, Kate Friedman, Hannah Grosman, Slayton Underwood, Danielle Halpern, Jessica Zweifach, Paige M. Siper, Alexander Kolevzon

“…Treatment of epilepsy in PMS may require multiple anticonvulsants, and in a minority of cases, seizures remain poorly controlled. …”
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Accurate identification of snoRNA targets using variational graph autoencoder to advance the redevelopment of traditional medicines by Zhina Wang, Zhina Wang, Yangyuan Chen, Hongming Ma, Hongming Ma, Hong Gao, Hong Gao, Yangbin Zhu, Hongwu Wang, Nan Zhang, Nan Zhang

“…Furthermore, these diseases often involve multiple targets, making the redevelopment of traditional medicines highly promising. …”
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CHI study: protocol for an observational cohort study on ageing and mental health in community-dwelling older adults by Lei Feng, Lieng Hsi Ling, Qiushi Feng, Rachael Zhi Yi Lee, Junhong Yu, Iris Rawtaer, Patrick Finbarr Allen, Zhiming Bao, Jeong Kyu Lee, Chin Tat Lim, Leng Leng Thang, Thet Naing, D Y Wang, Kai Zhen Yap, EH Kua, Rathi Mahendran

“…The Community Health and Intergenerational study aims to holistically examine ageing in place by investigating the resilience and vulnerability factors of the ageing process in the biological, psychological and social domains within the environment.Methods and analysis Using a cohort multiple randomised controlled trial design, comprehensive health profiles of community-dwelling older adults will be collected. …”
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A Novel Construction of Substitution Box Based on Polynomial Mapped and Finite Field With Image Encryption Application by Abid Mahboob, Muhammad Asif, Imran Siddique, Aysha Saleem, Muhammad Nadeem, Dariusz Grzelczyk, Jan Awrejcewicz

“…This scheme based on polynomial mapped and finite field which work only for even integers without multiple of 4 in the range (2-254). Firstly, we take a quadratic polynomial mapped for the construction of S-box from the newly designed map. …”
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Sociocultural and Socioeconomic Influences on Type 2 Diabetes Risk in Overweight/Obese African-American and Latino-American Children and Adolescents by Rebecca E. Hasson, Tanja C. Adam, Jay Pearson, Jaimie N. Davis, Donna Spruijt-Metz, Michael I. Goran

“…., integration, assimilation, separation, and marginalization), household social position and FSIGT parameters were assessed using multiple linear regression. Results. For African-Americans, integration (integrating their family’s culture with those of mainstream white-American culture) was positively associated with AIRG (β=0.27±0.09, r=0.48, P<0.01) and DI (β=0.28±0.09, r=0.55, P<0.01). …”
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Metallicity Dependence of Giant Planets around M Dwarfs by Tianjun Gan, Christopher A. Theissen, Sharon X. Wang, Adam J. Burgasser, Shude Mao

“…With the refined stellar and planetary parameters, we examine the stellar metallicities and the masses of giant planets where we find no significant correlation. M dwarfs with multiple giant planets or with a single giant planet have similar stellar metallicities. …”
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Association between prognostic nutritional index and all-cause mortality and cardiovascular disease mortality in American adults with non-alcoholic fatty liver disease by Yuqing Lei, Shaohong Tao, Yubo Yang, Fang Xie, Weining Xie

“…To examine the relationship between PNI and both all-cause and cardiovascular mortality, we employed weighted Cox regression models with multiple variables. Kaplan–Meier survival curves were utilized to visualize the survival distribution across different levels of PNI. …”
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Human Health, Ecosystem Quality, and Resource Scarcity Burdens Inflicted by Livestock Production Across Chinese Regions by Yixuan Shao, Qilin Cao, Junnian Song, Jiahao Xing, You Wu, Cheng Sun, Pan He, Wei Yang

“…Herein, we construct a life cycle framework covering multiple livestock species, feeding regimes, and activities to evaluate nine environmental impacts ending up as human health, ecosystem quality and resource scarcity burdens in Chinese provincial regions. …”
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Development of Cross-Sector Collaboration Indicators for Accelerating the Reduction of Stunting in South Sulawesi, Indonesia by Balqis Balqis, Suci Rahmadani, Muh. Yusri Abadi, St. Rosmanely, Arif Anwar, Laksmi Trisasmita, Ni Made Viantika Sulianderi, Faizal Fahmi, Arsunan Arsin, Muh. Amri Arfandi, Nur Annisa Hamka, Amaliah Amriani. AS

“…Background: To reduce stunting, the government of Indonesia, which has the fifth-highest prevalence of stunting in toddlers, launched the National Strategy for the Acceleration of Stunting Prevention (StraNas Stunting). Despite involving multiple sectors, stunting rates remain high. This research aimed to develop cross-sector collaboration indicators to assess the effectiveness of cross-sector efforts in reducing stunting. …”
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