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17661
Oleuropein in olive leaf, branch, and stem extracts: stability and biological activity in human cervical carcinoma and melanoma cells
Published 2023-12-01“…Olive leaves as a main byproduct of olive oil and fruit industry are a valuable source of phytochemicals such as polyphenols, with multiple biomedical effects. Apart from leaves, olive branches and stems make up a significant amount of olive waste. …”
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17662
Neuropathic Pain Management: Prescription Strategies in a Tertiary Care Setting
Published 2025-01-01“…While these strategies align with clinical guidelines, they also underscore the need for careful management to minimize the risks associated with multiple drug regimens. Future research should focus on optimizing treatment protocols and integrating non-pharmacological interventions to improve patient outcomes.…”
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17663
Improved Systemic Inflammation is Associated with Functional Prognosis in Post-Stroke Patients
Published 2024-12-01“…The primary outcomes were the motor items of the Functional Independence Measure (FIM-motor) at discharge. We applied multiple linear regression analysis to examine whether reduced systemic inflammation was associated with outcomes after adjusting for confounding factors. …”
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17664
Development and Application of a LC-MS/MS Method for Simultaneous Quantification of Four First-Line Antituberculosis Drugs in Human Serum
Published 2020-01-01“…MS detection was performed by a triple quadrupole tandem mass spectrometer in the multiple reaction monitoring mode with a positive electrospray ionization source. …”
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17665
Cocaine-Induced Giant Bullous Emphysema
Published 2020-01-01“…A 50-year-old male with a history of chronic cocaine abuse was found unresponsive in the field and given multiple doses of naloxone without any improvement in mental status. …”
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17666
Pressure-relief and anti-impact technology of near-fault blasting by high-level roadway in deep pressure bumps mine
Published 2024-12-01“…Anti-rockburst effect of the new pressure relief blasting technology is comprehensively evaluated from multiple dimensions. The results show that: the maximum expansion radius of the explosive fracture zone obtained by in-situ monitoring was 1.5 m, and the hole bottom distance and the charge quantity designed accordingly can ensure the breaking effect of the fault; the microseismic event of 104 energy level decreased from 5.2 % before stopping mining to 1.5 % after recovering mining, and no 105 and 106 energy level events occurred. …”
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17667
A structural analysis of ordered Cs3Sb films grown on single crystal graphene and silicon carbide substrates
Published 2025-01-01“…We found that Cs3Sb films grew with flat, fiber-textured surfaces on 3C-SiC and with multiple ordered domains and sub-nanometer surface roughness on graphene-coated 4H-SiC under our growth conditions. …”
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17668
Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment
Published 2023-03-01“…We used single-cell analysis with encoded peptide-human leukocyte antigen (HLA) tetramers to analyze HPV16+ and HPV33+ OPSCC tumors, characterizing the ex vivo cellular responses to HPV-derived antigens presented in major Class I and Class II HLA alleles.Results We identified robust cytotoxic T-cell responses to HPV16 proteins E1 and E2 that were shared across multiple patients, particularly in HLA-A*01:01 and HLA-B*08:01. …”
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17669
DR Loss-Free Dithering-Based Digital Background Linearity Calibration for SAR-Assisted Multi-Stage ADCs With Digital Input-Interference Cancellation
Published 2024-01-01“…We also describe a capacitor-scanning dither method to accomplish simultaneous and independent identification of multiple bit weights. In addition, a digital-domain input-interference cancellation (IIC) technique is proposed to accelerate the convergence speed of the correlation-based calibration. …”
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17670
Advanced progress in the genetic modification of the oncolytic HSV-1 virus
Published 2025-01-01“…Its large genome can accommodate insertions over 30 kb or deletions of multiple virulence genes without compromising lytic replication in tumor cells. …”
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17671
Prevalence, characteristics, and treatment outcome of congenital malaria in Nigeria: a systematic review
Published 2025-01-01“…Studies were retrieved from multiple electronic databases such as PubMed, EMBASE, Google Scholar, Scopus, Web of Science, African Journals Online (AJOL), and Cochrane Library and subjected to a multistage screening per established eligibility criteria. …”
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17672
Exploring the impact of occupational exposure: A study on cardiovascular autonomic functions of male gas station attendants in Sri Lanka
Published 2024-11-01“…These workers are exposed to hydrocarbon fuels associated with multiple health effects by modulation of the autonomic nervous system. …”
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17673
Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda
Published 2025-02-01“…Microsatellites 313, Poly-α, and 383 exhibited the highest diversity, while PfPK2 and Poly-α revealed elevated multiplicity of infection (MOI) across all sites. The 3/3 match-counting algorithm classified significantly fewer recrudescences than both the ≥ 2/3 and Bayesian algorithms at probability cutoffs of ≥ 0.7 and ≥ 0.8 (P < 0.05). …”
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17674
Light and dark biofilm adaptation impacts larval settlement in diverse coral species
Published 2025-01-01“…Although these taxa were generally specific to each coral species, we observed bacteria classified as Flavobacteriaceae, Rhodobacteraceae, Rhizobiaceae and Pirellulaceae to be consistently correlated with larval settlement across multiple coral species. Conclusions Our work identifies novel microbial groups that significantly influence coral larval settlement, which can be targeted for the discovery of settlement-inducing metabolites for implementation in reef restoration programs. …”
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17675
Comparative Genomic Analysis of <i>Campylobacter</i> Plasmids Identified in Food Isolates
Published 2025-01-01“…The mega plasmids carry multiple genes (e.g., <i>aph</i>(3’)-III, type IV and VI secretion systems, and type II toxin–antitoxin systems) important for plasmid mobilization, virulence, antibiotic resistance, and the persistence of <i>Campylobacter</i>. …”
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17676
Cochlear implantation and cognitive function in the older adult population: current state of the art and future perspectives
Published 2025-05-01“…Given the narrative nature of this review, no strict inclusion or exclusion criteria were applied, allowing for a broad overview of the current state-of-the-art literature on the effects of cochlear implantation on cognitive functioning, the challenges of studying cognition in this population and future research directions. Results: Multiple studies have been able to demonstrate an improvement of cognitive functioning in older adults with severe-to-profound hearing loss after cochlear implantation. …”
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17677
Assessing the impact of climate and land use change on flood vulnerability: a machine learning approach in coastal region of Tamil Nadu, India
Published 2025-01-01“…To identify flooded areas, the study utilised Google Earth Engine (GEE), Sentinel-1 data, and 12 geospatial datasets from multiple sources. A random forest algorithm was used for LULC change and flood susceptibility mapping. …”
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17678
Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions
Published 2018-01-01“…Presence of WML, hypertension, or diabetes mellitus was not found to be correlated with storage urinary symptoms or OAB-V8 total score. Multiple logistic regression analysis did not show the presence of WML to be associated with the diagnosis of OAB (adjusted OR 1.13, 95% CI 0.65–1.96, p=0.659). …”
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17679
Development of a 50K SNP array for whole-genome analysis and its application in the genetic localization of eggplant (Solanum melongena L.) fruit shape
Published 2024-11-01“…IntroductionCurrent eggplant variety breeding is still mainly based on conventional methods, and there remains a lack of effective molecular breeding systems for complex traits controlled by multiple genes, such as yield and quality. To accelerate the research progress of eggplant genetics and molecular breeding, it is necessary to implement a genome-based breeding strategy.MethodsTherefore, in this study, a SNP array containing 50K liquid-phase probes was designed on the basis of the resequencing data of 577 eggplants.ResultsThe developed 50K liquid-phase probes were used to perform targeted capture sequencing on 12 eggplant lines, and the efficiency of probe capture exceeded 99.25%. …”
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17680
Cost-effectiveness of metacognitive therapy for cardiac rehabilitation participants with symptoms of anxiety and/or depression: analysis of a randomised controlled trial
Published 2024-12-01“…Missing data were imputed using multiple imputation. Uncertainty was explored by probabilistic bootstrapping. …”
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