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17521
Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA)
Published 2025-12-01“…Identified CpGs and/or nearby genes have been implicated in cellular development pathways, transcription factor binding, cancer and multiple autoimmune and/or inflammatory diseases. Of the identified CpGs (7 individual CpGs and 11 within DMRs), two CpGs and one CpG within a DMR were associated with expression of cis genes NDUFS5, AK1RIN1, NCF4 and ADSSL1. …”
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17522
Projected Spatiotemporal Evolution of Urban Form Using the SLEUTH Model with Urban Master Plan Scenarios
Published 2025-01-01“…This study aims to assess the spatiotemporal patterns of urban growth and morphological evolution in mainland Shanghai from 2016 to 2060 using the SLEUTH model under multiple growth scenarios based on the Shanghai Urban Master Plan (2017–2035). …”
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17523
A multiresolution approach with method-informed statistical analysis for quantifying lymphatic pumping dynamics
Published 2025-01-01“…This approach not only offers detailed insights into lymphatic pumping behaviors across species, sex and age, but also significantly boosts the reliability of these measurements by incorporating multiple regions of interest and evaluating the lymphatic system under various gravitational loads. …”
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17524
Harnessing the power of proteins in modulation of miRNAs for targeting Iron deficiency Anemia: Opinion for future implications and strategies
Published 2025-01-01“…Proteins, acting as modulators of miRNA activity, present innovative pathways for intervention by influencing erythropoiesis at multiple stages, from stem cell proliferation to red blood cell maturation. …”
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17525
Predictive modeling and optimization of noise emissions in a palm oil methyl ester-fueled diesel engine using response surface methodology and artificial neural network integrated...
Published 2025-03-01“…By employing different engine speeds and loads within the low to high range, noise emissions were recorded from multiple engine components to evaluate the performance of each predictive model. …”
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17526
Effect of cooling medium temperature on cooling curve and microstructure of Ti65 alloy
Published 2025-01-01“…The effect of oil temperature on the cooling curve is mainly attributed to changes in oil viscosity and fluidity, while the effect of air temperature on the cooling curve is mainly attributed to multiple complex factors such as air density and temperature gradient.…”
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17527
Downregulation of RIPK4 Expression Inhibits Epithelial-Mesenchymal Transition in Ovarian Cancer through IL-6
Published 2021-01-01“…RIPK4 has been implicated in multiple cancer types, but its role in ovarian cancer (OC) has not been clearly elucidated. …”
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17528
Molecular Epidemiology of SARS-CoV-2 Variants in Vaccinated and Non-Vaccinated Patients of Erbil Province, Kurdistan Region-Iraq
Published 2024-06-01“…Multiple new SARS-CoV-2 variants of concern (VOC) have emerged globally since the onset of the COVID-19 pandemic. …”
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17529
Pattern of Bacterial Pathogens and Their Susceptibility Isolated from Surgical Site Infections at Selected Referral Hospitals, Addis Ababa, Ethiopia
Published 2016-01-01“…More than 58 (75%) of the Gram negative isolates showed multiple antibiotic resistance (resistance ≥ 5 drugs). …”
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17530
Evaluating a large language model’s ability to answer clinicians’ requests for evidence summaries
Published 2025-01-01“…Methods: Questions were extracted from an in-house database of clinical evidence requests previously answered by medical librarians. Questions with multiple parts were subdivided into individual topics. …”
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17531
Pathological Features of Mitochondrial Ultrastructure Predict Susceptibility to Post-TIPS Hepatic Encephalopathy
Published 2018-01-01“…A score ≤2 (no or low damage) was defined as group A, and a score >2 (high damage level) was defined as group B; routine follow-up was required at 1 and 2 years; the incidence of PSE and multiple clinical data were recorded. Results. A total of 78 cases in group A and 42 in group B completed the study. …”
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17532
Phage vB_KlebPS_265 Active Against Resistant/MDR and Hypermucoid K2 Strains of <i>Klebsiella pneumoniae</i>
Published 2025-01-01“…Horizontal transfer even involved conservative genes and led to clear genomic mosaicism, indicating multiple recombination events in the ancestral phages during evolution.…”
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17533
Trifarotene alleviates skin photoaging injury by inhibition of JNK/c-Jun/MMPs
Published 2024-09-01“…Long-term exposure to ultraviolet (UV) radiation induces skin photoaging, which manifests as oxidative stress, inflammation, and collagen degradation. Multiple approaches (topical or systemic retinoids, antioxidants, alpha-hydroxy acids, laser, surgery) are used in the treatment of photoaged skin, and the use of topical retinoids is currently a primary clinical treatment. …”
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17534
Oxidative stress and dysregulated long noncoding RNAs in the pathogenesis of Parkinson’s disease
Published 2025-01-01“…LncRNAs and oxidative stress are correlated during neurodegenerative processes: oxidative stress affects the expression of multiple lncRNAs, while lncRNAs regulate many genes involved in oxidative stress responses. …”
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17535
First Clinical Evidence About the Use of a New Silver-Coated Titanium Alloy Instrumentation to Counteract Surgical Site Infection at the Spine Level
Published 2025-01-01“…The patients were re-evaluated at multiple endpoints in order to assess the rate of reinfection and the local and general complications. …”
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17536
Effect of sleep quality on the severity of perimenstrual symptoms in Japanese female students: a cross-sectional, online survey
Published 2025-02-01“…The MDQ scores were compared between two groups (normal-sleep quality and low-sleep quality) using Mann-Whitney U test. In addition, multiple logistic regression analysis was performed, and the MDQ subscales that showed significant differences between the groups were used as independent variables. …”
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17537
Metal Biomonitoring Through Arboreal Species in Riparian Ecosystems: <i>Pithecellobium dulce</i> as a Bioindicator Species
Published 2025-01-01“…However, it is polluted by multiple wastewater discharges from different origins, with toxic metals being the main pollutants. …”
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17538
Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity
Published 2025-01-01“…In this study, we performed an integrative analysis of multiple single-cell RNA sequencing datasets to interrogate the cellular heterogeneity and fibroblast-like entities in degenerative human NP specimens. …”
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17539
Intraocular Foreign Bodies: Clinical Characteristics and Prognostic Factors Influencing Visual Outcome and Globe Survival in 373 Eyes
Published 2019-01-01“…Excellent visual outcome (defined as ≥0.5 logMAR) was associated with age <50 years (P=0.003); better presenting visual acuity (PVA) (P<0.001); wound length <4 mm (P=0.005); absence of vitreous hemorrhage (P=0.026) and retinal breaks (P<0.001); nonvitrectomy surgery (P=0.043); and use of balanced saline (P=0.029). Conclusions. Multiple prognostic factors were identified that may predict visual outcome and globe survival after IOFBs injury. …”
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17540
Mosquito‐derived ingested DNA as a tool for monitoring terrestrial vertebrates within a peri‐urban environment
Published 2025-01-01“…Furthermore, the study also examined the influence of a human blocking primer and the application of multiple primers on the detection of the targeted taxa. …”
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