Two new species of Plagiostomum (Prolecithophora, Plagiostomidae) from China with its morphology, phylogeny, and reproductive strategy by Leyuan Feng, Shiyan Zhang, Ming Tao, Ting Sun, Antai Wang

“…Additionally, Plagiostomum plagae sp. nov. can be distinguished from P. nanhaiensis sp. nov. and other congeneric species by its two connected dorsal stripes, multiple spherical testes arranged along the ventral midline, a hemispherical vesicula seminalis located on the right ventral side, and grain-shaped sperm. …”
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NF-κB/AP-1-Targeted Inhibition of Macrophage-Mediated Inflammatory Responses by Depigmenting Compound AP736 Derived from Natural 1,3-Diphenylpropane Skeleton by Van Thai Ha, Heung Soo Beak, Eunji Kim, Kwang-Soo Baek, Muhammad Jahangir Hossen, Woo Seok Yang, Yong Kim, Jun Ho Kim, Sungjae Yang, Jeong-Hwan Kim, Yung Hyup Joo, Chang Seok Lee, Joonho Choi, Hong-Ju Shin, Sungyoul Hong, Song Seok Shin, Jae Youl Cho

“…Furthermore, AP736 also downregulated the expression of multiple inflammatory genes, such as inducible NO synthase (iNOS), cyclooxygenase- (COX-) 2, and interleukin- (IL-) 1β in LPS-treated RAW264.7 cells. …”
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Regulation of reactive oxygen species and the role of mitochondrial apoptotic-related genes in rheumatoid arthritis by Conghui Gao, Chengqiang Zhang, Lixing Wen, Gailian Zhang, Xiaoping Liu, Jie Wang, Luping Cui, Rui Li, Tingting Nie, Jiaoniu Duan, Yingying Guo

“…In addition, biomarkers are expressed in plasmablasts, with CD74 as a key receptor binding multiple ligands. RA biomarkers (MRPS10, EEF2, HSPA9, TUFM) linked to energy & ROS, progression tied to AMPK/mTOR, CD74-MIF crucial. …”
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Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo by Rui D. Alvites, Mariana V. Branquinho, Ana C. Sousa, Irina Amorim, Rui Magalhães, Filipa João, Diogo Almeida, Sandra Amado, Justina Prada, Isabel Pires, Federica Zen, Stefania Raimondo, Ana L. Luís, Stefano Geuna, Artur S. P. Varejão, Ana C. Maurício

“…Despite the existence of multiple possible therapeutic approaches, until now, there is no consensus regarding the advantages of each option or the best methodology in promoting nerve regeneration. …”
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A LASSO-derived clinical score to predict severe acute kidney injury in the cardiac surgery recovery unit: a large retrospective cohort study using the MIMIC database by Qi Guo, Jingjing Huang, Yuewei Li, Hongwei Li, Jingfeng Wang, Yong Xie, Tucheng Huang, Wanbing He, Wenyu Lv, Jieping Huang, Yangxin Chen

“…Decision curve analysis demonstrated that the model could achieve a net benefit.Conclusion A clinical score built by using LASSO regression and logistic regression to screen multiple clinical risk factors was established to estimate the probability of severe AKI in CSRU patients. …”
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Colossal permittivity with ultra-wide temperature stability in Bi + Ca co-doped BaTiO3 by Tingting Fan, Qi Shi, Wenrong Xiao, Guangzu Zhang, Feng Huang, Wenlin Wang, Wen Dong, Shenglin Jiang, Jing Wang

“…In this work, the mechanism of multiple polarization was creatively introduced, and the temperature stability and dielectric properties of BaTiO3-based ceramics are simultaneously enhanced. …”
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Preschool and Me: Educational-clinical linkage to improve health equity for children with developmental delays and disabilities from historically marginalized communities by Tina L. Schuh, Kathleen R. Diviak, Sarai Coba-Rodriguez, Emily Pela, Raphael Kinney, Michael L. Berbaum, Amanda Klemas, Kruti Acharya, Molly Martin, Reshma Shah

“…Combining key components of CCLs with a personalized medical-education care plan and remote navigator support, PreM targets multiple levels of influence impacting access to school-based therapeutic and educational services. …”
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Analyzing Drivers of Tropical Moist Forest Dynamics in the Kahuzi-Biega National Park Landscape, Eastern Democratic Republic of Congo from 1990 to 2022 by Nadège Cizungu Cirezi, Jean-François Bastin, Yannick Mugumaarhahama, Yannick Sikuzani Useni, Katcho Karume, Raymond Sinsi Lumbuenamo, Jan Bogaert

“…This included meshing, multi-scale analysis, principal component analysis, zoning, multiple linear regression, and relative importance analysis through bootstrapping. …”
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Purification, Characterization and Antibacterial Mechanism of Plantaricin 2-1 by Mengyang LI, Xiaoxue CHE, Qingshen SUN

“…These results suggested that P2-1 can cause multiple damages to indicator bacteria and ultimately lead to bacterial death. …”
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Hearing loss prevalence and burden of disease in China: Findings from provincial-level analysis by Yu Wang, Yang Xie, Minghao Wang, Mengdan Zhao, Rui Gong, Ying Xin, Jia Ke, Ke Zhang, Shaoxing Zhang, Chen Du, Qingchuan Duan, Fang Wang, Tao Pan, Furong Ma, Xiangyang Hu, Jing Ni

“…We estimated the national prevalence using multiple linear regression of the age-group proportions and prevalence in 31 provinces with clustering analysis. …”
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Modification of Platelet Count on the Association between Homocysteine and Blood Pressure: A Moderation Analysis in Chinese Hypertensive Patients by Jianan Zhang, Jing Li, Shi Chen, Linglin Gao, Xiaoluan Yan, Mingzhi Zhang, Jia Yu, Fenchun Wang, Hao Peng

“…Leveraging a community-based cross-sectional survey in 30,369 Chinese hypertensive patients (mean age 62 years, 52% female), we examined the moderation of platelet count on the association between serum homocysteine and BP by constructing hierarchical multiple regression models, adjusting for conventional risk factors. …”
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Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen by Michael L. McCaleb, Steven G. Hughes, Tamar R. Grossman, Ashley Frazer-Abel, Bill Jung, Lixuan Yin, Scott P. Henry, Brett P. Monia, Eugene Schneider, Richard Geary, Gary T. Brice

“…An over-active alternative complement pathway has been implicated in the pathophysiology of multiple diseases, including IgA nephropathy and geographic atrophy secondary to age related macular degeneration. …”
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Feruloyl-amides as natural antimicrobials for crop and food protection by Denise Dozio, Sharmila Ghosh, Daniele Alessandro Consolini, Josè Luis Ermini Starna, Loris Pinto, Federico Baruzzi, Martina Letizia Contente, Andrea Pinto, Paolo Cortesi, Salvatore Princiotto, Andrea Kunova, Sabrina Dallavalle

“…Abstract Background Plants have developed multiple chemical defence responses against pathogen attacks. …”
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A Novel Procedure for Real-Time SOH Estimation of EV Battery Packs Based on Time Series Extrinsic Regression by Raimondo Gallo, Tommaso Monopoli, Marco Zampolli, Remi Jacques Philibert Jaboeuf, Paolo Tosco, Edoardo Patti, Alessandro Aliberti

“…We defined a Simulink-based EV simulator, modeling a specific real-world EV, and we utilized it to generate a synthetic dataset by simulating multiple driving sessions of the EV to compensate for the lack of large-scale publicly available EV monitoring data. …”
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Genome- and Transcriptome-Wide Characterization and Expression Analyses of bHLH Transcription Factor Family Reveal Their Relevance to Salt Stress Response in Tomato by Jianling Zhang, Xiaoying Liu, Zuozhen Yin, Tiantian Zhao, Dan Du, Jing Li, Mingku Zhu, Yueying Sun, Yu Pan

“…The expression profiles of selected <i>SlbHLHs</i> were varyingly and markedly induced by multiple abiotic stresses and hormone treatments. These results provide valuable information to further understand the significance and intricacy of the bHLH transcription factor family, and lay a foundation for further exploring functions and possible regulatory mechanisms of SlbHLH members in abiotic stress tolerance, which will be significant for the study of tomato stress resistance and agricultural productivity.…”
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Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy by Yonghua Cai, Heng Xiao, Shuaishuai Xue, Peng Li, Zhengming Zhan, Jie Lin, Zibin Song, Jun Liu, Wei Xu, Qixiong Zhou, Songtao Qi, Xi’an Zhang, Ziyi Luo

“…Methods We comprehensively analyzed PANoptosis-related genes (PANoRGs) in multiple glioma cohorts, identifying different PANoptosis patterns and constructing the PANoptosis enrichment score (PANoScore) to evaluate its relationship with patient prognosis and immune activity. …”
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The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia by Elise P. Legault, Paula A. B. Ribeiro, Danielle Moreau-Amaru, Emmanuelle Robert, Sara Forte, Alain S. Comtois, Vanessa Samouëlian, François Tournoux

“…Patients with endometrial neoplasia (EN) often have multiple comorbidities and a higher surgical risk. …”
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An Evaluation of the Responsiveness and Discriminant Validity of Shoulder Questionnaires among Patients Receiving Surgical Correction of Shoulder Instability by Kyle A. R. Kemp, David M. Sheps, Lauren A. Beaupre, Fiona Styles-Tripp, Charlene Luciak-Corea, Robert Balyk

“…Those experiencing a frank dislocation or multiple episodes of subluxation reported a 20% decline. …”
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Determinants of readiness to implement forensic patient-oriented research: a study of barriers and facilitators in a high-secure hospital by Cara Evans, Cara Evans, Sevil Deljavan, Kayla Zimmermann, Kayla Zimmermann, Kristy Allen, Elnaz Moghimi, Christopher Canning, Christopher Canning

“…Coding was initially informed by the Consolidated Framework for Implementation Research, and subsequent iterations of analysis extended beyond this framework to explore patterns of meaning encompassing multiple implementation domains.ResultsWe identified three themes in our data: “Navigating a climate of distrust, discrimination, and restricted autonomy”; “Hearing and interpreting patient voices”; and “Experiencing a slow shift in the tide.” …”
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Deep-learning based electromagnetic navigation system for transthoracic percutaneous puncture of small pulmonary nodules by Muyun Peng, Xinyi Fan, Qikang Hu, Xilong Mei, Bin Wang, Zeyu Wu, Huali Hu, Lei Tang, Xinhang Hu, Yanyi Yang, Chunxia Qin, Huajie Zhang, Qun Liu, Xiaofeng Chen, Fenglei Yu

“…We developed a novel electromagnetic navigation puncture system for the puncture of sub-centimeter lung nodules by combining multiple deep learning models with electromagnetic and spatial localization technologies. …”
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