“One is not Born, but Rather Becomes, a Woman”: Impressions of Women on the Career in Agribusiness and its Spaces by Heliani Berlato, Danilo Andretta, Thais Fernandes

“…Both clusters demarcate tensions about how women see discrimination and experience the multiple unfoldings of sexist behaviors and attitudes that permeate their career pathways in agribusiness.…”
Get full text

Design of double layer satellite constellation based on distributed satellite clusters by Ji JIANG, Mugen PENG, Wenbo WANG

“…Nowadays,the land communication system is unable to support the complex information needs,and realizing global seamless coverage and high capacity through space information network is anticipated.The existing satellite network is mainly composed of single satellite constellation,which absents the cooperation between the low earth orbit (LEO) satellites and geostationary orbit (GEO) satellites.A double-layer satellite constellation based on distributed satellite clusters was proposed,in which the infrastructure layer was composed of LEO satellites,the communication between LEO satellites was accomplished over inter-satellite links (ISL),and GEO satellites enhance the performance of coverage in low and middle latitudes.As simulation results show,the proposed approach can realize excellent global multiple coverage only relying on the deployment of satellite earth stations in China.…”
Get full text

Territorial development, tourism, and the protection of World Heritage Sites: issues of geopolitical conflict by Mark Bailoni

“…As with other types of conflict, World Heritage listing reinforces the planning conflict by generating multiple interests, responding to contradictory functional, heritage, landscape, and identity considerations.…”
Get full text

Multi-attribute aware scheduling for inter-datacenter bulk transfers by Yang-yang LI, Hong-bo WANG, Peng ZHANG, Jian-kang DONG, Shi-duan CHENG

“…A multi-attribute decision making method to schedule inter-datacenter bulk data was proposed.First,hierarchical analysis was used to analyze the dominant relationship among attributes.Based on the relative weights of attributes which were calculated via information entropy,the evaluation to each intermediate data center was provided.Then the multi-attribute aware scheduling problem was modeled on a time expanded graph and formulated as a minimal cost flow problem.Finally,the scheme with general store-and-forward mechanism and single attribute based approach under several different simulation settings was compared.The results demonstrate that our strategy can take multiple attributes into consideration,and can find the bulk transfer route with the best integrated evaluation.…”
Get full text

Cooperation mechanism of multi-agent system driven by utility by Han-bing DENG, Xia ZHANG, Ji-ren LIU

“…A cooperative mechanism amlong multiple agents was proposed. In the cooperative mechanism, a utility value was used to generate a preferred order for agents under different cooperative patterns. …”
Get full text

Henrique Soares Carneiro, Transformaciones del significado de la palabra “droga”: de las especias coloniales al prohibicionismo contemporáneo by David Herrera Castrillón, Henrique Soares Carneiro

“…Abstract Henrique Carneiro's text analyzes the conceptual evolution that gives the term "drug"a multiplicity of meanings, ranging from poison to medicine, from original substances of the country to phytotherapeutic medicines, and also examines the conflicts between indigenous knowledge and its appropriation by colonial society.…”
Get full text

Genomic Profiling of Liver Cancer by Ju-Seog Lee

“…Novel approaches combining multiple datasets from patient tissues have created an unparalleled opportunity to uncover potential new therapeutic targets and prognostic/predictive biomarkers for personalized therapy that can improve clinical outcomes of the patients with liver cancer.…”
Get full text

Midostaurin shapes macroclonal and microclonal evolution of FLT3-mutated acute myeloid leukemia by Romane Joudinaud, Augustin Boudry, Laurène Fenwarth, Sandrine Geffroy, Mikaël Salson, Hervé Dombret, Céline Berthon, Arnaud Pigneux, Delphine Lebon, Pierre Peterlin, Simon Bouzy, Pascale Flandrin-Gresta, Emmanuelle Tavernier, Martin Carre, Sylvie Tondeur, Lamya Haddaoui, Raphael Itzykson, Sarah Bertoli, Audrey Bidet, Eric Delabesse, Mathilde Hunault, Christian Récher, Claude Preudhomme, Nicolas Duployez, Pierre-Yves Dumas

“…In patients receiving ICT + MIDO, detection of multiple FLT3-ITD clones was associated with a higher FLT3-ITD persistence rate at R/R disease (multiple clones: 88% vs single clones: 57%; P = .049). …”
Get full text

Altered Atlas of Exercise-Responsive MicroRNAs Revealing miR-29a-3p Attacks Armored and Cold Tumors and Boosts Anti-B7-H3 Therapy by Jie Mei, Zhiwen Luo, Yun Cai, Renwen Wan, Zhiwen Qian, Jiahui Chu, Yaying Sun, Yuxin Shi, Ying Jiang, Yan Zhang, Yongmei Yin, Shiyi Chen

“…In this research, expression and prognostic values of exercise-responsive miRNAs were examined in breast cancer (BRCA) and further pan-cancer types. In addition, multiple independent public and in-house cohorts, in vitro assays involving multiple, macrophages, fibroblasts, and tumor cells, and in vivo models were utilized to uncover the tumor-suppressive roles of miR-29a-3p in cancers. …”
Get full text

Remote-sensing-based forest canopy height mapping: some models are useful, but might they provide us with even more insights when combined? by N. Besic, N. Picard, C. Vega, J.-D. Bontemps, L. Hertzog, J.-P. Renaud, J.-P. Renaud, F. Fogel, M. Schwartz, A. Pellissier-Tanon, G. Destouet, F. Mortier, F. Mortier, M. Planells-Rodriguez, P. Ciais

“…This has resulted in the availability of multiple, sometimes conflicting, sources of information, but, at face value, it also makes it possible to learn about forest attribute uncertainty through the joint interpretation of multiple models. …”
Get full text

Safety and Intranasal Retention of a Broad-Spectrum Anti-SARS-CoV-2 Monoclonal Antibody SA55 Nasal Spray in Healthy Volunteers: A Phase I Clinical Trial by Chaoying Hu, Yibo Zhou, Xing Meng, Jianhua Li, Jinxia Chen, Zhifang Ying, Xiaoliang Sunney Xie, Yaling Hu, Yunlong Cao, Ronghua Jin

“…Healthy participants aged 18–65 years were enrolled and received a single dose of the SA55 nasal spray (1 mg or 2 mg) or multiple doses of SA55 nasal spray/placebo for 7 days (1 or 2 mg/dose, 3 or 6 doses/day). …”
Get full text

Neoandrographolide inhibits mature osteoclast differentiation to alleviate bone loss and treat osteoporosis by Kai Tang, Kai Tang, Kai Tang, Wei Deng, Wei Deng, Wei Deng, Wei Deng, Zhiying Huang, Zhiying Huang, Zhiying Huang, Simin Chen, Simin Chen, Simin Chen, Zilin Zhu, Zilin Zhu, Shukun Lin, Shukun Lin, Lubin Zhong, Lubin Zhong, Quanxin Zheng, Quanxin Zheng, Wenhua Zhao, Wenhua Zhao, Zhida Zhang, Zhida Zhang, Ling Mo, Ling Mo, Ling Mo

“…Additionally, NEO affects the phosphorylation of proteins in the PI3K/AKT, GSK3β, and PPARγ signaling pathways, demonstrating that NEO can inhibit OC formation through multiple pathways and targets. In vivo experiments further validated the in vitro findings by constructing an OP model, showing that NEO can mitigate bone loss induced by OC differentiation.ConclusionNEO has the potential to serve as a therapeutic agent for OP by targeting multiple sites and inhibiting the formation of mature OC through various signaling pathways.…”
Get full text

Global variation in the assessment of psychological trauma in pregnancy by Kathryn Wall, Francesca Penner, Lindsey Wallace Goldman, Jin Young Shin, Eloise Novak, Amanda Lowell, Michèle Day, Lea Papa, Drew Wright, Soudabeh Givrad, Helena J. V. Rutherford

“…The fewest number of studies was conducted across multiple regions. We found that most studies measuring psychological trauma in pregnancy across the nine geopolitical regions assessed interpersonal trauma, and the fewest number of studies assessed healthcare trauma. …”
Get full text

The Generation and Modulation of Distinct Gamma Oscillations with Local, Horizontal, and Feedback Connections in the Primary Visual Cortex: A Model Study on Large-Scale Networks by Chuanliang Han, Tian Wang, Yujie Wu, Yang Li, Yi Yang, Liang Li, Yizheng Wang, Dajun Xing

“…Our study, for the first time, pinpoints the underlying circuits for distinct GAMMAs in a mechanistic model for macaque V1, which might provide a new framework to study multiple gamma oscillations in other cortical regions.…”
Get full text

Assessing alcohol industry penetration and government safeguards: the International Alcohol Control Study by Sarah Callinan, Gopalkrishna Gururaj, Shiwei Liu, Sally Casswell, Thomas Karlsson, Jintana Jankhotkaew, Surasak Chaiyasong, Pranil Man Singh Pradhan, Gillian Shorter, Timothy Naimi, Ingeborg Rossow, Keitseope Nthomang, June Yue Yan Leung, Mindaugas Štelemėkas, Mom Kong, Khem Karki, Steve Randerson, Lathika Athauda, Arvind Banavaram, Orfhlaith Campbell, Song Dearak, Emeka W Dumbili, Laura Romero-García, Romtawan Kalapat, Norman Danilo Maldonado Vargas, Juan Felipe Gonzalez-Mejía, Opeyemi Oladunni, Kwame Owino, Juan Camilo Herrera Palacio, Phasith Phatchana, Vanlounny Sibounheuang, Dao The Son, Kate Vallance, Wim van Dalen, Ashley Wettlaufer, Arianne Zamora

“…It was challenging to obtain publicly available information on multiple indicators of alcohol industry penetration.Conclusion Governments need to put in place stronger measures to protect policies from alcohol industry influence, including restricting interactions and partnerships with the alcohol industry, limiting political contributions and enhancing transparency. …”
Get full text

The multi-omics signatures of telomere length in childhood by Congrong Wang, Dries S. Martens, Mariona Bustamante, Rossella Alfano, Michelle Plusquin, Lea Maitre, John Wright, Rosemary R. C. McEachan, Johanna Lepeule, Remy Slama, Marina Vafeiadi, Leda Chatzi, Regina Grazuleviciene, Kristine B. Gutzkow, Hector Keun, Eva Borràs, Eduard Sabidó, Angel Carracedo, Georgia Escarami, Augusto Anguita-Ruiz, Dolors Pelegrí-Sisó, Juan R. Gonzalez, Martine Vrijheid, Tim S. Nawrot

“…In addition, a literature-guided, sparse supervised integration method was applied to multiple omics, and latent components were extracted as predictors of child telomere length. …”
Get full text

Pathogen community composition and co-infection patterns in a wild community of rodents by Abbate, Jessica L., Galan, Maxime, Razzauti, Maria, Sironen, Tarja, Voutilainen, Liina, Henttonen, Heikki, Gasqui, Patrick, Cosson, Jean-François, Charbonnel, Nathalie

“…Bacterial communities were characterized using 16S rRNA amplicon sequencing of splenic samples. Multiple correspondence (MCA), multiple regression and association screening (SCN) analyses were used to determine the degree to which extrinsic factors (study year and site; host habitat, species, sex and age class) contributed to pathogen community structure, and to identify patterns of associations between pathogens within hosts. …”
Get full text

Exosomes Derived from Schistosoma japonicum Cystatin-Treated Macrophages Attenuated CLP-Induced Sepsis in Mice by Feifei Huang, Yayun Qian, Huihui Li, Liang Chu, Chen Wan, Qili Shen, Qianqian Li, Xiuxiu Li, Xinyue Wu, Bin Zhan, Rui Zhou, Xiaodi Yang

“…Sepsis is a disease caused by multiple microbial infections resulting in multiple organ failure. …”
Get full text

Relationship between emotional labor strategies and the quality of work life of operating room nurses by Li Li, Yingjuan Cao, Yingjuan Cao, Yingjuan Cao, Yinuo Sun, Yue Li, Yonghua Zhai, Yonghua Zhai, Yonghua Zhai, Yan Yan, Yan Yan, Yan Yan

“…Statistical analyses, including descriptive statistics, Pearson correlation analysis, and multiple stratified regression, were applied to explore the relationships between variables.ResultsA total of 372 valid responses were obtained, with an effective response rate of 94.18%. …”
Get full text

A nomogram for predicting mortality risk in geriatric patients with hip fractures complicated by pneumonia: A multicenter study by Kaiming Zhang, Xiangwei Li, Yujia Xiao, Cheng Zhou, Yu Liu, Fan Zhen, Hao Zhang, Mao Nie

“…Patients were divided into the P group (patients with hip fractures complicated with pneumonia) and the C group (patients with hip fractures without pneumonia) and demographic characteristics, mortality, postoperative outcomes, and perioperative comorbidities of the patients were analyzed. Multiple logistic regression was then used to identify independent risk factors for inpatient mortality in the P group and a nomogram was constructed to predict inpatient mortality. …”
Get full text