Entrepreneurial Budgeting in the Iranian Government Budget: Obstacles and Solutions by Seyyed Mohammad Moghimi, Alireza Salmanian

“…The legislative (relationship between parliament and government, structure of interests, technical competence of representatives, governance of local and regional perspectives), executive (oil rent, government inefficiency, technical and structural problems, governance of political and ideological perspectives, economic instability), and supervisory (traditional approach, multiple supervisory institutions, lack of universal supervision) have been classified; under each, the most important relevant issues are listed and explained Conclusion By analyzing the data obtained from interviews and reviewing and delving into the comprehensive themes, three components of governance structure, mismanagement of oil revenues, and weak domestic production and civil society can be identified as the roots of emerging problems and other obstacles in establishing entrepreneurial budgeting in the country. …”
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Determination of Sequential Well Placements Using a Multi-Modal Convolutional Neural Network Integrated with Evolutionary Optimization by Seoyoon Kwon, Minsoo Ji, Min Kim, Juliana Y. Leung, Baehyun Min

“…This complex multi-million-dollar problem involves optimizing multiple parameters using computationally intensive reservoir simulations, often employing advanced algorithms such as optimization algorithms and machine/deep learning techniques to find near-optimal solutions efficiently while accounting for uncertainties and risks. …”
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Identity Construction and Transformation of Zen Tourists by Xu Haichao, Liang Zengxian

“…It constructs the "space-situation-identity" conceptual framework, highlighting that the identity transformation of Zen tourists involves multiple factors from space and situation, while their new identities influence the elements of space and situation. …”
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Hyperglycemia Is a Potential Prognostic Factor for Exacerbation in Severe Psoriasis with Diabetes or Prediabetes by Yongpisarn T, Thadanipon K, Suchonwanit P, Rattanakaemakorn P

“…Interestingly, insulin resistance may also worsen psoriatic skin lesions. Multiple studies have found a correlation between psoriasis severity and hemoglobin A1C (HbA1c, average blood sugar levels for the last 3 months); however, it is unknown whether hyperglycemia can also cause psoriasis exacerbation. …”
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Barriers and drivers to exclusive breastfeeding in Kyrgyzstan: a qualitative study with mothers and health workers by Cath Jackson, Marina Duishenkulova, Nurila Altymysheva, Jyldyz Artykbaeva, Raisa Asylbasheva, Eleonora Jumalieva, Anastasia Koylyu, Sian Lickess, Tursun Mamyrbaeva, Veerle Snijders, Julianne Williams, Tiina Likki

“…Health workers were recommending and supporting women with exclusive breastfeeding during multiple antenatal and postnatal interactions during the initial six months. …”
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Stress and Coping of Parents with Children Seeking Treatment from a Tertiary Care Mental Health Institute by Stuti Sharma Lohar, Arunjyoti Baruah, Sandeep Kollipara

“…Regarding the way of coping frequently used by the participants, 36% of participants had used positive reappraisal coping followed by multiple (two or more). Coping measures were used by 25% of participants and planful problem-solving by 20% of participants. …”
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Associations between disease severity, depression, health-related quality of life, and physical activity in adults with sickle cell disease by Adekola B. Ademoyegun, Mutiu A. Adeyemo, Babatunde Y. Adewuyi, Adebukola G. Ibitoye, Olalekan I. Akerele, Taofeek O. Awotidebe, Chidozie E. Mbada

“…Data on DS, depression, HRQoL, and PA were assessed through modified disease severity scoring protocol, patient health questionnaire-9, 12-item short-form health survey, and international physical activity questionnaire short-form, respectively. Multiple hierarchical regression and mediation analyses were applied. …”
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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

“…By RNA-sequencing and experiments in vitro using multiple ovarian cancer cell models as well as in vivo using subcutaneous xenografts assay and in situ transplantation ovarian cancer model in nude mice, we further demonstrated that RAB8A positively mediated OC progression through activating HH signaling pathway by disassociating the protein–protein complex formation of GLI and SuFu (Suppressor of Fused), which reciprocally enhanced GPR137 activity, forming a regulation loop between HH signaling and GPR137. …”
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Detection and characterization of multidrug resistant Escherichia coli carrying virulence gene isolated from broilers in Bangladesh by Md. Sirazul Islam, Chandan Nath, F. M. Yasir Hasib, Tahia Ahmed Logno, Md. Helal Uddin, Mohammad Mahmudul Hassan, Sharmin Chowdhury

“…All isolates were MDR, with a multiple antibiotic resistance indexes were <0.3. A significant percentage (16.38%) of E. coli isolates were MDR to five antimicrobial classes and harboured blaTEM, sul1, ere (A), tetA, tetB and tetC genes. …”
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Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…Transcriptome analysis revealed that aging and surgery downregulated multiple neurogenesis-related genes in the hippocampus. …”
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Psychological well-being and academic performance of Ukrainian medical students under the burden of war: a cross-sectional study by Mykhaylo Korda, Arkadii Shulhai, Oksana Shevchuk, Oleksandra Shulhai, Anna-Mariia Shulhai, Anna-Mariia Shulhai

“…Academic performance in 2023 was significantly lower compared to the pre-war period in 2019 (p &lt; 0.001) (p = 0.000). The multiple linear regression analysis showed that academic performance was positively associated with depression (p = 0.003), hyperarousal (p &lt; 0.001), anxiety (p = 0.03), and negatively associated with stress (p = 0.002).ConclusionUkrainian medical students in rear areas are facing various challenges, with war-related stressors having a profound impact on their mental health. …”
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Acinetobacter baumannii infection in critically ill patients with COVID-19 from Tehran, Iran: the prevalence, antimicrobial resistance patterns and molecular characteristics of iso... by Mahsa Ghamari, Fereshteh Jabalameli, Shirin Afhami, Shahnaz Halimi, Mohammad Emaneini, Reza Beigverdi

“…The data demonstrate the dissemination of a single A. baumannii clone carrying multiple ARGs within our hospital. Regarding the limited therapeutic options, it is crucial to implement effective prevention and containment policies to curb the spread of these strains.…”
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Assessment of Learning Styles of First-year Medical Students’ using VARK 8.02 Model Questionnaire: A Cross-sectional Study by Senthil Ganesh P Kannappan, Ravichandran Doraisamy, Vijayakumar Jagadesan

“…Subsequently, a copy of the VARK questionnaire version 8.02, which contains 16 multiple-choice questions, was issued to the first-year MBBS students. …”
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Optimized methods for the targeted surveillance of extended-spectrum beta-lactamase-producing Escherichia coli in human stool by Sarah Gallichan, Sally Forrest, Esther Picton-Barlow, Claudia McKeown, Maria Moore, Eva Heinz, Nicholas A. Feasey, Joseph M. Lewis, Fabrice E. Graf

“…We found that enriching stool in a nutrient broth for 4 h, then plating the bacterial suspension on antibiotic-selective MacConkey agar, and finally extracting DNA from the bacteria using a specific DNA purification kit resulted in improved recovery of ESBL E. coli and high-quality DNA. Sequencing multiple isolates from stool allowed us to distinguish unambiguously and at high resolution between different variants of ESBL E. coli present in stool.…”
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Human-genome single nucleotide polymorphisms affecting transcription factor binding and their role in pathogenesis by E. V. Antontseva, A. O. Degtyareva, E. E. Korbolina, I. S. Damarov, T. I. Merkulova

“…It should be noted that the presence of an association does not allow one to identify a functional, truly disease-associated DNA sequence variant among multiple marker SNPs that are detected due to linkage disequilibrium. …”
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Long-term neuropsychologic outcome of pre-emptive mTOR inhibitor treatment in children with tuberous sclerosis complex (TSC) under 4 months of age (PROTECT), a two-arm, randomized,... by Jan H. Driedger, Julian Schröter, PROTECT-Study Group, Steffen Syrbe, Afshin Saffari

“…Abstract Background Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder affecting multiple organ systems, with a prevalence of 1:6,760–1:13,520 live births in Germany. …”
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Systemic hypotension and low perfusion pressure as risk factors for primary open-angle glaucoma progression by O.S. Myakonkaya, A.S. Sarkisyan, A.V. Seleznev, A.V. Kuroyedov, A.Yu. Brezhnev

“…., blood pressure (BP) and ocular perfusion pressure (OPP). Multiple published data have shown a decrease in blood flow velocity in the retrobulbar vessels, choroid, retina, and optic nerve in patients with glaucoma. …”
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A Novel, Patient-Specific Mathematical Pathology Approach for Assessment of Surgical Volume: Application to Ductal Carcinoma in situ of The Breast by Mary E. Edgerton, Yao-Li Chuang, Paul Macklin, Wei Yang, Elaine L. Bearer, Vittorio Cristini

“…Based on this prediction, we hypothesize that the volume of breast with ducts affected by in situ tumors at the time of diagnosis will be closely approximated by a model-derived mathematical function based on the ratio of tumor cell proliferation-to-apoptosis indices and on the extent of diffusion of cell nutrients (diffusion penetration length), which can be measured from immunohistochemical and morphometric analysis of patient histopathology specimens without the need for multiple-time measurements. We tested this idea in a retrospective study of 17 patients by staining breast tumor specimens containing ductal carcinoma in situ for mitosis with Ki-67 and for apoptosis with cleaved caspase-3 and counting cells positive for each marker. …”
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Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancers by Pragya Sinha, Faye M Johnson, Soma Ghosh, Jagannadha K Sastry, Madison P O'Hara, Tuhina Mazumdar, Lacin Yapindi

“…In each treatment group, we determined the tumor growth kinetics and long-term survival and assessed the tumor immune microenvironment using polychromatic flow cytometry.Results Aurora A inhibition induced apoptosis, DNA damage, and ICD in vitro in multiple human and murine HPV-positive cancer cell lines. …”
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A Local Adversarial Attack with a Maximum Aggregated Region Sparseness Strategy for 3D Objects by Ling Zhao, Xun Lv, Lili Zhu, Binyan Luo, Hang Cao, Jiahao Cui, Haifeng Li, Jian Peng

“…Additionally, neural rendering is used to obtain gradient-propagating multi-angle augmented data and suppress the model’s detection to locate universal critical decision regions from multiple angles. These technical strategies ensure that the adversarial modifications remain effective across different viewpoints and conditions. …”
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