Heavy metals contamination in geothermal medicinal plant extract; Chromolaena odorata Linn by A. Abubakar, H. Yusuf, M. Syukri, R. Nasution, M. Yusuf, R. Idroes

“…The presence of cadmium in the extract at a high concentration could cause its translocation to the human body, eventually leading to multiple organ damage. Therefore, the extract of Chromolaena odorata leaves collected from a geothermal area should be consumed with caution for possible cadmium intoxication.…”
Get full text

The assessment of the tear film lipid layer in different types of dry eye syndrome by T.N. Safonova, V.V. Averich, E.S. Medvedeva

“…</p> <p> <b>Results</b>: in 70% of cases, an incomplete eyelid closure was detected in the group of patients with BES, while the multiplicity of blinking movements was within the normal range. …”
Get full text

The Dose-Dependent Effects of Spironolactone on TGF-β1 Expression and the Vulnerability to Atrial Fibrillation in Spontaneously Hypertensive Rats by Mirong Tang, Yan Chen, Fuqing Sun, Liangliang Yan

“…After 7 weeks of gavage, a multiple electroconductive physiological recorder was used to detect atrial electrical parameters, including P-wave duration, PR interval, and atrial effective refractory period (AERP), the inducibility, and duration of atrial fibrillation. …”
Get full text

Thyroid function during COVID-19 and post-COVID complications in adults: a systematic review by Anisha Panesar, Palma Gharanei, Natasha Khovanova, Lawrence Young, Dimitris Grammatopoulos, Dimitris Grammatopoulos

“…COVID-19 primarily targets the respiratory system but also affects multiple organ systems, including the endocrine system. …”
Get full text

Analisis Pengaruh Kualitas Layanan Terhadap Kepuasan Pelanggan dan Loyalitas Pengguna Aplikasi Jenius Menggunakan Model E-S- Qual dan E- Recs- QUal (Studi Kasus: Pengguna Aplikasi... by Alfansya Achmad Mulyadi, Satrio Hadi Wijoyo, Hanifah Muslimah Az-Zahra

“…This research uses purposive sampling as a sampling technique and multiple and simple linear regression analysis as a technique in data analysis. …”
Get full text

Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus by Aimei Li, Bin Yi, Yan Liu, Jianwen Wang, Qing Dai, Yuxi Huang, Yan Chun Li, Hao Zhang

“…Urinary NGAL and RBP both correlated negatively with eGFR and positively with plasma IL-6 and 8-OHdG. Multiple linear regression indicated NGAL (β=−0.287, p=0.008) and RBP (β=−44.545, p<0.001) were independently correlated with eGFR. …”
Get full text

Urbanización de áreas ribereñas del rio Limay en Neuquén y Plottier. by Pablo Leyes Zabala, José Aravena, Elsie Jurio

“…Las ciudades de Neuquén y Plottier, ubicadas en el Alto Valle de la provincia del Neuquén, manifiestan un continuo crecimiento que se refleja en una expansión desordenada con múltiples y constantes contrariedades. El presente trabajo analiza una de las problemáticas que se da en torno a las urbanizaciones próximas al río Limay, las cuales ocupan áreas potencialmente inundables. …”
Get full text

Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2 by An W, Luo J, Zhang C, Xiao Q

“…Functionally, administration of celecoxib, a PTGS2-specific inhibitor, into mice significantly reduced β-aminopropionitrile-induced AAD development and progression.Conclusion: Through an integrative bioinformatics analysis, we have identified multiple key AAD-related FRGs including PTGS2. Functional studies also suggest a functional role of PTGS2 in ferroptosis and AAD development, offering novel insights into pathogenesis of human AAD.Keywords: aortic aneurysm and dissection, PTGS2, macrophage, ferroptosis, integrative bioinformatics analysis…”
Get full text

Search for and functional annotation of multi-domain PLA2 family proteins in flatworms by M. E. Bocharnikova, I. I. Turnaev, D. A. Afonnikov

“…In free-living flatworms PLA2 genes have multiple copies. In parasitic flatworms, on the contrary, loss of genes occur specifically in individual taxa specifically for groups or sub­families of PLAs. …”
Get full text

Intricate interplay of CRISPR-Cas systems, anti-CRISPR proteins, and antimicrobial resistance genes in a globally successful multi-drug resistant Klebsiella pneumoniae clone by Jianping Jiang, Astrid V. Cienfuegos-Galletd, Tengfei Long, Gisele Peirano, Tingyu Chu, Johann D. D. Pitout, Barry N. Kreiswirth, Liang Chen

“…Abstract Background Klebsiella pneumoniae is one of the most prevalent pathogens responsible for multiple infections in healthcare settings and the community. …”
Get full text

Preferences of Integrated Care and the Influencing Factors Among Chinese Community-Dwelling Older Adults by Liu S, Zhao J, Liu N, Qin T, Wang F

“…The study aimed to elicit the preferred care patterns and the influencing factors of integrated health and social care among community-dwelling older adults in multiple regions of China.Methods: From a national survey, 1184 community-dwelling older adults in three cities across China were included in the study. …”
Get full text

Inequalities in ownership and availability of home-based vaccination records in 82 low- and middle-income countries by Aluísio J D Barros, Cesar G Victora, Daniel R Hogan, M Carolina Danovaro-Holliday, Bianca O Cata-Preta, Thiago M Santos, Andrea Wendt, Luisa Arroyave, Tewodaj Mengistu

“…We studied levels and inequalities in HBR ownership in low-income and middle-income countries (LMICs) using data from national surveys conducted since 2010.Methods We used data from national household surveys (Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS)) from 82 LMICs. 465 060 children aged 6–35 months were classified into four categories: HBR seen by the interviewer; mother/caregiver never had an HBR; mother/caregiver had an HBR that was lost; and reportedly have an HBR that was not seen by the interviewer. …”
Get full text

Microclima y fauna edáfica asociada a tres densidades de arborización en finca ganadera del municipio Jimaguayú. Camagüey by Oscar Loyola Hernández, Delmy Triana González, Isael Pérez Cabrera, Vivian Sánchez Jerez

“…Las medias se compararon a través de la prueba de rangos múltiples HSD Tukey, para un nivel de significación de p< 0,05. …”
Get full text

Impact of Arterial Remodeling of Intermediate Coronary Lesions on Long-Term Clinical Outcomes in Patients with Stable Coronary Artery Disease: An Intravascular Ultrasound Study by Liang Geng, Peizhao Du, Yuan Yuan, Liming Gao, Yunkai Wang, Jiming Li, Qi Zhang

“…After adjusting for multiple covariates, negative remodeling remained an independent determinant for vessel-oriented clinical event (HR: 4.849, 95% CI 1.542–15.251, P=0.007). …”
Get full text

Under-five mortality and its associated factors in sub-Saharan Africa: a multilevel analysis of recent demographic and health surveys data based on Bayesian approach by Atalay Liknaw Birhanie, Zemenu Tadesse Tessema, Bekalu Endalew, Koku Sisay Tamirat

“…In sub region of SSA, it was 65 in central, 52 in eastern, 50 in southern and 73 in western region per 1000 live births. Multiple birth (AOR = 5.27; 95%CrI: 4.72, 5.87), number of under-five children 3 to 5 (AOR = 3.31; 95%CrI: 3.01, 3.60), caesarean section delivery (AOR = 1.64; 95%CrI: 1.47, 1.83), being unmarried (AOR = 1.16; 95%CrI 1.08, 1.26), using unimproved toilet (AOR = 1.08;95%CrI: 1.02, 1.16), birth order of 4th to 6th (AOR = 1.18; 95%CrI:1.1, 1.25),were risk factors of under-five mortality. …”
Get full text

Longitudinal Changes of Sensorimotor Resting-State Functional Connectivity Differentiate between Patients with Thalamic Infarction and Pontine Infarction by Peipei Wang, Zhenxiang Zang, Miao Zhang, Yanxiang Cao, Zhilian Zhao, Yi Shan, Qingfeng Ma, Jie Lu

“…The family-wise error (FWE) method was used to account for multiple comparison issues using SPM software. Post hoc repeated-measure ANOVA was applied to examine longitudinal FC reorganization. …”
Get full text

Augmentation index as a predictor of right ventricular dysfunction in coronary artery disease: a cross-sectional study by Arash Rahimi, Babak Geraiely, Hamed Vahidi, Mohammadreza Eftekhari, Ramyar Rahimi Darehbagh, Somayeh Mohammadi, Golrokh Ghaffari, Meysam Khoshavi

“…This association is evident across multiple echocardiographic parameters of RV systolic function and is independent of traditional cardiovascular risk factors, left ventricular systolic function, and the extent of coronary artery disease. …”
Get full text

Tousled-like kinase loss confers PARP inhibitor resistance in BRCA1-mutated cancers by impeding non-homologous end joining repair by Min-ah Kim, Banseok Kim, Jihyeon Jeon, Jonghyun Lee, Hyeji Jang, Minjae Baek, Sang-Uk Seo, Dongkwan Shin, Anindya Dutta, Kyung Yong Lee

“…Loss-of-function experiments were performed in multiple human cancer cell lines using siRNA-mediated knockdown or CRISPR-Cas9 gene knockout. …”
Get full text

Concentration of traffic air pollutants and influencing metrological factors in Hawassa City roadways, Ethiopia by Asmare Asrat Yirdaw, Amanuel Ejeso, Samrawit Mokie Belayneh, Lamrot Yohannes, Anmut Endalkachew Bezie, Embialle Mengistie Beyene

“…Kendall’s tau-b correlation analysis suggested that Meteorological parameters (temperature and relative humidity) were positively correlated with traffic air pollutants. Likewise, stepwise multiple linear regression analysis confirms that the concentrations of traffic air pollutants had a positive relationship with metrological parameters.ImplicationsThe findings of this study therefore showed the need for regular air quality monitoring of the urban areas to copping out the adverse public health impacts. …”
Get full text

Polymorphism of Dehydrocholesterol Reductase (DHCR7) Gene and its Effects on Metabolic Components of Polycystic Ovary Syndrome in Women: A Cross-sectional Study from Tertiary Care... by Susmita Banerjee, Shuvankar Mukherjee, Anindya Dasgupta, Palash Kusum Ghosh

“…Introduction: Polycystic Ovary Syndrome (PCOS) is a disorder characterised by various metabolic derangements with multiple origins, one of which may be linked to vitamin D metabolism. …”
Get full text