Critically ill adult patients with acute leukemia: a systematic review and meta-analysis by Dara Chean, David Luque-Paz, Daniele Poole, Sofiane Fodil, Etienne Lengliné, Thibault Dupont, Achille Kouatchet, Michael Darmon, Élie Azoulay

“…Secondary outcomes included reasons for ICU admission, use of organ support therapies (mechanical ventilation, vasopressors and renal replacement therapy), hospital, day-90 and one-year mortality rates. Results Of the 1,331 studies screened, 136 (24,861 patients) met the inclusion criteria and were included in the meta-analysis. …”
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Validation of the REDS score in hospitalised patients who deteriorated and were admitted to the intensive care unit—a retrospective cohort study by Narani Sivayoham, Oliver Mason, Harriet O’Mara, Natasha Trenchard Turner, Katie Sysum, Georgina Wicks

“…Delayed identification and transfer to the intensive care unit (ICU) are known to be associated with increased mortality rates. The Risk-stratification of Emergency Department suspected Sepsis (REDS) score was derived and validated in emergency department patients with suspected sepsis. …”
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Global, regional, and national disease burden attributable to high systolic blood pressure in youth and young adults: 2021 Global Burden of Disease Study analysis by Chuan He, Saien Lu, Haijie Yu, Yingxian Sun, Xueyao Zhang

“…The primary outcomes were disability-adjusted life years (DALYs), mortality rates, and estimated annual percentage change. …”
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Clinical Characteristics and Outcomes in Patients with Ruptured Middle Cerebral Artery Aneurysms: A Multicenter Study in Northern China by Xiuhu An, Jingliang Su, Bingxin Duan, Long Zhao, Bangyue Wang, Yan Zhao, Tianxing Li, Shuai Zhou, Xinyu Yang, Zhenbo Liu

“…The 3-month and 2-year mortality rates were 15.5% and 18.2%, respectively. The risk factors for mortality were identified via Cox regression and were as follows: age > 70 years, previous stroke, combined intracerebral hemorrhage (ICH)/intraventricular hemorrhage (IVH), poor Hunt and Hess grade, multiple aneurysms, and conservative treatment (CT). …”
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Integration of single-cell transcriptomics and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of nucleotide metabolism in lung adenocarcinoma by Kai Zhang, Kai Zhang, Luyao Wang, Huili Chen, Lili Deng, Mengling Hu, Ziqiang Wang, Yiluo Xie, Chaoqun Lian, Xiaojing Wang, Xiaojing Wang, Jing Zhang

“…BackgroundLung adenocarcinoma (LUAD) is a highly aggressive tumor with one of the highest morbidity and mortality rates in the world. Nucleotide metabolic processes are critical for cancer development, progression, and alteration of the tumor microenvironment. …”
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Effects of public roads on wildlife-vehicle collisions in two protected areas, Hluhluwe-iMfolozi Park and iSimangaliso Wetland Park, in KwaZulu-Natal, South Africa by Cameron T. Cormac, Cormac Price, Wendy Collinson, Dave J. Druce, Jarryd P. Streicher, Colleen T. Downs

“…Our results showed that intervention is needed along portions of the two public roads in both protected areas, particularly during the wet season, with mortality rates as high as 13 carcasses per km. Mitigation measures should be implemented to reduce the number of wildlife mortalities along the roads in both locations, with specific measures to mitigate small vertebrate road mortalities. …”
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Quality of care delivery in patients with acute heart failure: insights from the international REPORT-HF registryResearch in context by Wan Ting Tay, Tiew-Hwa Katherine Teng, Wouter Ouwerkerk, Christiane E. Angermann, Kenneth Dickstein, John G.F. Cleland, Ulf Dahlstrom, Georg Ertl, Mahmoud Hassanein, Sergio V. Perrone, Mathieu Ghadanfar, Anja Schweizer, Achim Obergfell, Sean P. Collins, Gerasimos Filippatos, Carolyn S.P. Lam, Jasper Tromp

“…We investigated how QoC varied by region and its relationship with mortality rates at 30 days and 1 year after hospital discharge. …”
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Drp1–associated genes implicated in sepsis survival by Marissa D. Pokharel, Marissa D. Pokharel, Anlin Feng, Anlin Feng, Ying Liang, Ying Liang, Wenli Ma, Wenli Ma, Saurabh Aggarwal, Hoshang Unwalla, Stephen M. Black, Stephen M. Black, Stephen M. Black, Ting Wang, Ting Wang, Ting Wang

“…Despite advances in medical treatment, current therapies are often inadequate, with high septic mortality rates. Therefore, there is a critical need for reliable prognostic markers to be used in clinical settings to improve the management and outcomes of patients with sepsis. …”
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Assessing the detection and interaction of Lawsonia intracellularis and porcine circovirus 2 in low and high-performance wean-to-finish pig groups in different porcine reproductive... by Guilherme Cezar, Fernando L. Leite, Eduardo Fano, Reid Phillips, John Waddell, Kate Dion, Edison Magalhães, Giovani Trevisan, Gustavo Silva, Daniel C. Linhares

“…Groups with relatively high genomic copies of PCV2 and L. intracellularis that had PRRSV detection presented higher mortality rates (15.75%).DiscussionThis study expanded our understanding of PRRSV, PCV2, and L. intracellularis co-detections and their impact on swine populations.…”
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Systematic Review of Surgical Care in the Incarcerated Population: Identifying Knowledge Gaps for Future Research by Totadri Dhimal, MD, Paula Cupertino, PhD, Aqsa Ghaffar, BS, Yue Li, PhD, Xueya Cai, PhD, Cristopher Soto, BS, Megha Ramaswamy, PhD, MPH, Bruce W. Herdman, PhD, Fergal J. Fleming, MD, MPH, Anthony Loria, MD, MSCI

“…Notable complications, such as nonfusion and postarthroplasty infections, were more prevalent in incarcerated individuals compared with nonincarcerated individuals. Trauma-related mortality rates were similar, despite lower intraabdominal injuries following penetrating abdominal injuries in incarcerated patients. …”
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Prevalence, risk factors, and prognostic implications of intraoperative bleeding during CF-LVAD implant by Ibrahim Mortada, MD, Christos Kourek, MD, PhD, Rupesh Kshetri, MD, Arun Singhal, MD, Anthony Panos, MD, Alexandros Briasoulis, MD, PhD, Mohammed Mhanna, MD, MPH, Shareef Mansour, MD, Kristine Yumul, MD, Paulino Alvarez, MD, Ernesto Ruiz Duque, MD

“…Early events of postoperative bleeding have been associated with higher morbidity and mortality rates. Our study aims at identifying potential predictors of intraoperative bleeding, defined as 4 or more units of packed red blood cells transfused during surgery. …”
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Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers by Gaetano Zizzo, Gabriele Guazzardi, Daniela Bompane, Francesco Di Terlizzi, Giorgio Rotola, Ilario Stefani, Michela Medugno, Mario Bucalo, Antonino Mazzone

“…Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. …”
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Perinatal outcomes and predictors of placental abruption: a retrospective study in an Ethiopian tertiary care center by Mesfin Tadese, Gebresenbet Getachew, Tirusew Nigussie Kebede, Toyba Ebrahim Yesuf, Saba Desta Tessema, Wogene Asefa Damesa, Gebeyehu Shumet Solomon

“…In Ethiopia, the maternal and perinatal morbidity and mortality rates are alarmingly high, and placental abruption significantly contributes to these adverse outcomes. …”
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The Impact of Hyperoxia on Outcome of Patients Treated with Noninvasive Respiratory Support by Seyhan Pala Cifci, Yasemin Urcan Tapan, Bengu Turemis Erkul, Yusuf Savran, Bilgin Comert

“…Conservative oxygen therapy strategy can be suggested to decrease the hyperoxia prevalence and mortality rates.…”
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Establishment and validation of predictive model of ARDS in critically ill patients by Senhao Wei, Hua Zhang, Hao Li, Chao Li, Ziyuan Shen, Yiyuan Yin, Zhukai Cong, Zhaojin Zeng, Qinggang Ge, Dongfeng Li, Xi Zhu

“…Abstract Background Acute respiratory distress syndrome (ARDS) is a prevalent complication among critically ill patients, constituting around 10% of intensive care unit (ICU) admissions and mortality rates ranging from 35 to 46%. Hence, early recognition and prediction of ARDS are crucial for the timely administration of targeted treatment. …”
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Comprehensive Sepsis Risk Prediction in Leukemia Using a Random Forest Model and Restricted Cubic Spline Analysis by Kou Y, Tian Y, Ha Y, Wang S, Sun X, Lv S, Luo B, Yang Y, Qin L

“…Yanqi Kou,1,2,* Yuan Tian,2,3,* Yanping Ha,2,3,* Shijie Wang,1,* Xiaobai Sun,1 Shuxin Lv,1 Botao Luo,2,3 Yuping Yang,2 Ling Qin1 1Department of Hematology, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan Province, People’s Republic of China; 2Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Guangdong Medical University, Zhanjiang City, Guangdong Province, People’s Republic of China; 3Department of Pathology, Guangdong Medical University, Zhanjiang City, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuping Yang, Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Guangdong Medical University, No. 2 Wenming East Road, Xiashan, Zhanjiang, Guangdong, 524000, People’s Republic of China, Email yangyupingchn@163.com Ling Qin, Department of Hematology, The First Affiliated Hospital and College of Clinical Medicine, Henan University of Science and Technology, 24 Jinghua Road, Jianxi District, Luoyang, Henan Province, 471003, People’s Republic of China, Email zzqq777@126.comBackground: Sepsis is a severe complication in leukemia patients, contributing to high mortality rates. Identifying early predictors of sepsis is crucial for timely intervention. …”
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Capital formation and production of carbon emissions in low-carbon development by E.S. Siregar, S.U. Sentosa, A. Satrianto

“…Low carbon development is a new platform to maintain economic growth through reducing carbon emissions and reducing the use of natural resources, because it was predicted that reducing emissions will increase economic growth while preventing forest loss, improving air quality and living standards, and reducing mortality rates.METHODS: Utilizing a quantitative method, this study integrates a novel viewpoint by combining low-carbon development with related emission factors. …”
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A MALDI-TOF MS-based multiple detection panel of drug resistance-associated multiple single-nucleotide polymorphisms in Candida tropicalis by Feifei Wan, Min Zhang, Jian Guo, Huiping Lin, Xiaoguang Zhou, Lixin Wang, Wenjuan Wu

“…The SNP panel enables identification of specific mutations at critical sites of drug-resistant strains to facilitate the rapid selection of appropriate antifungal agents and efficient monitoring of the regional epidemiological trends of resistance of C. tropicalis.IMPORTANCEC. tropicalis infections pose a growing global public health challenge, with mortality rates approaching 40%. C. tropicalis is one of the top four Candida spp. responsible for candidiasis, particularly in the Asia-Pacific region and Latin America, notably affecting patients with neutropenia and malignancies. …”
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After neonatal care, what next? A qualitative study of mothers’ post-discharge experiences after premature birth in Kenya by Justinah Maluni, Dorothy Oluoch, Sassy Molyneux, Mwanamvua Boga, Caroline Jones, Florence Murila, Mike English, Sue Ziebland, Lisa Hinton

“…Prominent healthcare structural and socio-economic factors in SSA, for example poverty and weak health systems, amplify vulnerabilities for mothers and premature babies; often leading to poor outcomes. Post-discharge mortality rates are high, and readmission is common. For mothers of premature babies, the transition home from hospital is marked by challenges and uncertainties. …”
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Machine Learning–Based Risk Factor Analysis and Prediction Model Construction for the Occurrence of Chronic Heart Failure: Health Ecologic Study by Qian Xu, Xue Cai, Ruicong Yu, Yueyue Zheng, Guanjie Chen, Hui Sun, Tianyun Gao, Cuirong Xu, Jing Sun

“… BackgroundChronic heart failure (CHF) is a serious threat to human health, with high morbidity and mortality rates, imposing a heavy burden on the health care system and society. …”
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