Patterns and predictors of mortality in a semi-urban population-based cohort in Sri Lanka: findings from the Ragama Health Study by Anuradhani Kasturiratne, Dileepa Senajith Ediriweera, Madunil Anuk Niriella, Hithanadura Janaka de Silva, Arunasalam Pathmeswaran, Shamila Thivanshi De Silva, Uthuru Beddage Thulani, Anuradha Supun Dassanayake, Arjuna Priyadarsin De Silva, Sureka Chackrewarthy, Udaya Ranawaka, Norihiro Kato, Ananda Rajitha Wickremasinghe

“…We also estimated the survival probabilities for men and women in each 10-year age group and standardised mortality ratio relative to the source population.Results There were 169 deaths over 10 years with standardised mortality rates of 5.3 and 2.4 per 1000 years of follow-up for men and women, respectively. …”
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Implementing a Care Model for Bedridden Stroke Survivors: A Qualitative Study in Northeastern Thailand by Panpanit L, Jongudomkarn D, Doungmungkorn A, Boontoch K, Neelasmith S, Manorat M, Maneerat T

“…Ladawan Panpanit,1 Darunee Jongudomkarn,2 Aurawan Doungmungkorn,3 Kwansuda Boontoch,4 Somsakhool Neelasmith,5 Monrudee Manorat,5 Thirakorn Maneerat6 1Gerontological Nursing Department, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand; 2Family and Community Nursing Department, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand; 3Research and Development Nursing Department, Khon Kaen Hospital, Khon Kaen, Thailand; 4Mental Health Nursing Department, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand; 5Midwifery Department, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand; 6Continuity of Care Nursing Department, Khon Kaen Hospital, Khon Kaen, ThailandCorrespondence: Somsakhool Neelasmith, Midwifery Department, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand, Email somsne@kku.ac.thBackground: Stroke remains a significant global health concern, including in Thailand, with high mortality rates. Despite investments in stroke prevention, inadequate support exists for severely disabled stroke survivors (SSs) and their caregivers, particularly in enhancing their quality of life.Purpose: This research aimed to explore the experiences of SSs receiving home care, develop and implement a care model to enhance community volunteer caregivers’ (CVCGs) capabilities, and evaluate the outcomes of this model for bedridden stroke survivors in Northeastern Thailand.Methods: A research and development study was conducted in low-income, semi-urban communities in Northeastern Thailand, comprising three phases: 1) situation analysis, 2) development of a community care model, and 3) implementation and evaluation. …”
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Long-term outcomes of Fontan palliation; the influence of the dominant ventricle by Abdelmonem M. Helal, Jameel Al-Ata, Nashwa Mostafa Badawy, Ahmed Abdelwahed, Wejdan Khaled Ba-Atiyah, Anhar Ali Baeshen, Abdullah J. Alata, Ahmed F. Elmahrouk, Mohammad S. Shihata, Ahmed A. Jamjoom, Samia Bekheet

“…Codominant patients experienced more arrhythmias and complete heart block, while operative mortality rates were similar across groups. During a median follow-up of 80 months, the freedom from surgical reintervention at 5, 10, and 15 years was highest in the left-dominant group (97%) compared to right dominance (93%, 78%) and codominance (97%, 87%). …”
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The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis by Tingting Lin, Tingting Lin, Huimin Wan, Jie Ming, Yifei Liang, Linxin Ran, Jingjing Lu

“…BackgroundSevere Community-Acquired Pneumonia (SCAP) is a serious global health issue with high incidence and mortality rates. In recent years, the role of biomarkers such as Connective Tissue Growth Factor (CTGF) and Milk Fat Globule-Epidermal Growth Factor 8 (MFG-E8) in disease diagnosis and prognosis has increasingly gained attention. …”
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Development and validation of a prognostic model for critically ill type 2 diabetes patients in ICU based on composite inflammatory indicators by Lin Liu, Yan-Bo Zhao, Zhuo-Ting Cheng, Ya-Hui Li, Yang Liu

“…Logistic and Cox regression analyses were used to evaluate the relationship between nine inflammatory indicators and ICU, 30-day, and 90-day mortality rates. Significant predictive variables were chosen using least absolute shrinkage selection operator (LASSO) regression from logistic regression results, and a prognostic prediction model was built with multivariate logistic regression. …”
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Exome sequencing in Nigerian children with early‐onset epilepsy syndromes by Ibitayo Abigail Ademuwagun, Yagoub Adam, Solomon Oladapo Rotimi, Steffen Syrbe, Maximilian Radtke, Julia Hentschel, Johannes R. Lemke, Ezekiel Adebiyi

“…The integration of genomic medicine into epilepsy management in Nigeria holds promising prospects for improving patient care and reducing mortality rates. Plain Language Summary This study represents the first published exome findings in Nigerian children with early‐onset epilepsy, revealing a genetic diagnosis in 27% of cases. …”
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Hispanic Patients Undergoing Spinal Fusion for Neuromuscular Scoliosis Sustain Health Inequalities by Armando S. Martinez, David Momtaz, Travis Kotzur, Alexandra McLennan, Abdullah Ghali, Farhan Ahmad, Ebubechi Adindu, Alan C. Santiago-Rodriquez, Ali Seifi, Brian Smith

“…Data included demographic and hospital variables, including days from admission to the procedure, length of stay, recovery time, total charge, discharge disposition, and mortality rates. In addition to ANOVA, Chi-Squares, and t-tests, multiple-linear and multiple-logistic regression models were designed and run to generate adjusted odds ratios. …”
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Specific plasma metabolite profile in intestinal Behçet’s syndrome by Cheng-cheng Hou, Hua-fang Bao, Chun-hui She, Hua-yu Chen, Guan-xing Pan, Hua-ning Chen, Hong-bing Rui

“…Abstract Background Intestinal Behçet’s syndrome (IBS) has high morbidity and mortality rates with serious complications. However, there are few specific biomarkers for IBS. …”
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Application of organoids in drug screening of gynecological malignant tumors by JIANG Yuanyuan, WEI Wenfei, WU Jingya, LI Huawen

“…Gynecologic malignant tumors are among the leading diseases threatening women’s lives and health, with the highest morbidity and mortality rates among all female diseases. These tumors originate from female reproductive organs and are typically classified based on the affected site. …”
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The Impact of Effective Vaccination on Clinical and Radiological Involvement in COVID-19 Patients by Coskun DOGAN, Deniz BILICI, Burcu ARPINAR YIGITBAS, Omer ZENGIN, Orhan ZOR, Oguzhan AKMAN, Ilyas KOCABAG, Gonul Seven YALCIN, Esra ERTAN YAZAR

“…In addition, although the vaccinated group was older, they had mortality rates similar to those of unvaccinated subjects.…”
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Geospatial distribution and predictors of postnatal care utilization during the critical time in Ethiopia using EDHS 2019: A spatial and geographical weighted regression analysis. by Muluken Chanie Agimas, Tigabu Kidie Tesfie, Nebiyu Mekonnen Derseh, Meron Asmamaw, Habtamu Wagnew Abuhay, Getaneh Awoke Yismaw

“…Sub-Saharan Africa contributes the highest maternal and newborn mortality rates. To reverse this problem, early postnatal care is the best strategy, but there is no study to show the spatial distribution and application of geographical weighted regression to show the effect of each predictor on early postnatal care across the geographic areas in Ethiopia using the recent EDHS 2019 data.…”
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“Unmasking the Uncommon”: A case series of multi-drug resistant Elizabethkingia meningoseptica causing late-onset sepsis and meningitis in preterm neonates [version 2; peer review:... by Anisha Maria Fernandes, Sinchana Bhat, Suchitra Shenoy M., Prajnha U.P.

“…Recent technological advances have enabled accurate speciation to guide therapy and reduce morbidity and mortality rates.…”
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Exploring the clinical profiles and management of juvenile dermatomyositis in Africa: a survey of African rheumatology care providers by Jessica Perfetto, Laura B. Lewandowski, Dawn M. Wahezi, Vanessa Ogega, Joan Ahimbisibwe, Kate Webb, Christiaan Scott, Angela Migowa

“…There was high prevalence of calcinosis (as high as 100%) and interstitial lung disease (ILD) (as high as 32%); mortality rates in Kenya (6/42; 14%) and Zambia (2/7; 29%) exceeded the 1–3% mortality reported in studies of high-income countries. …”
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The burden of Gastric Cancer and possible risk factors from 1990 to 2021, and projections until 2035: findings from the Global Burden of Disease Study 2021 by Niping Qin, Yangyan Fan, Tao Yang, Zhiping Yang, Daiming Fan

“…Abstract Background and objective Gastric cancer (GC) remains a significant global health challenge, characterized by high incidence and mortality rates, particularly in East Asia. A comprehensive understanding of the disease burden of gastric cancer is crucial for developing effective prevention and treatment strategies. …”
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Identification of core biomarkers for tuberculosis progression through bioinformatics analysis and in vitro research by Zhanpeng Chen, Qiong Wang, Quan Ma, Jinyun Chen, Xingxing Kong, Yuqin Zeng, Lanlan Liu, Shuihua Lu, Xiaomin Wang

“…Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a significant global public health issue with high mortality rates and challenges posed by drug-resistant strains, emphasizing the continued need for new therapeutic targets and effective treatment strategies. …”
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Predictive models and determinants of mortality among T2DM patients in a tertiary hospital in Ghana, how do machine learning techniques perform? by Godsway Edem Kpene, Sylvester Yao Lokpo, Sandra A. Darfour-Oduro

“…Studies from Africa including those from Ghana, consistently reveal high T2DM-related mortality rates. While previous research in the Ho municipality has primarily examined risk factors, comorbidity, and quality of life of T2DM patients, this study specifically investigated mortality predictors among these patients. …”
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Knowledge and attitudes of primary care physicians regarding acromegaly: a survey study with multinational participation by Aysen Kutan Fenercioglu, Ebru Unur Demircan, Gunay Can, Cem Sulu, Nurver Turfaner Sipahioglu, Hande Mefkure Ozkaya, Pinar Kadioglu

“…Abstract Background Acromegaly is a disease with high morbidity and mortality rates. The role of primary care physicians is very important in the early diagnosis of acromegaly. …”
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The Role of the Estimated Plasma Volume Variation in Assessing Decongestion in Patients with Acute Decompensated Heart Failure by Andreea-Maria Grigore, Mihai Grigore, Ana-Maria Balahura, Gabriela Uscoiu, Ioana Verde, Camelia Nicolae, Elisabeta Bădilă, Adriana-Mihaela Ilieșiu

“…At 6 months, rehospitalization occurred in 35% of G2 and 21% of G1 (<i>p</i> = 0.04), with mortality rates of 37% in G2 and 11% in G1 (<i>p</i> = 0.012). …”
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Association of liver biopsy pathology on outcome of patients undergoing heart transplantation by Lauren S. Eichenwald, MD, Raffi Karagozian, MD, Adam J. Eichenwald, PhD, John Morrissey, MD MBA, Saurav Kini, MD, Ariella Stein, MSCIS-HI, Amanda R. Vest, MBBS MPH

“…We determine the relationship between liver fibrosis severity and mortality rates for HT patients. Methods: A retrospective cohort study of adults listed for HT who underwent a liver biopsy for evaluation of early or advanced liver fibrosis from August 12, 2004 to February 16, 2022. …”
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NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis by Jung Hwan Yoon, Jeong-Kyu Kim, Jung Woo Eun, Hassan Ashktorab, Duane T. Smoot, Suk Woo Nam, Won Sang Park

“…Abstract Background Gastric cancer remains a significant global health challenge, characterized by poor prognosis and high mortality rates. Mitotic integrity and genomic stability are crucial in maintaining cellular homeostasis and preventing tumorigenesis. …”
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