Perfluorooctanoic acid induces abnormal heart development via aryl hydrocarbon receptor-mediated oxidative stress and apoptosis in zebrafish larvae by Xueyi CHEN, Tianchi MA, Kang WANG, Tao CHEN, Yan JIANG

“…Under a dissecting microscope, the survival rate, mortality rate, heart rate, and heart malformation rate of 72 hpf zebrafish larvae were assessed. …”
Get full text

Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

“…Finally, data from 15 503 patients with CHF in the multicentre eICU-CRD were used for external validation of the established nomogram.Results The inclusion criteria were met by 15 983 subjects, whose in-hospital mortality rate was 12.4%. Multivariate analysis determined that the independent risk factors were age, race, norepinephrine, dopamine, phenylephrine, vasopressin, mechanical ventilation, intubation, hepatic failure (HepF), heart rate, respiratory rate, temperature, systolic blood pressure (SBP), anion gap (AG), blood urea nitrogen (BUN), creatinine, chloride, mean corpuscular volume (MCV), red blood cell distribution width (RDW) and white cell count (WCC). …”
Get full text

Ambient air pollution and Alzheimer’s disease and other dementias: a global study between 1990 and 2019 by Cui Guo, Dongze Wu, Jun Yang, Xingcheng Lu, Xiang Yan Chen, Jun Ma, Changqing Lin, Alexis K. H. Lau, Yingzhao Jin, Ruiyun Li, Shenjing He

“…These data include age-standardised mortality rate (ASMR) and disability-adjusted life-years (DALYs) of AD and other dementias, ambient air pollution (fine particulate matter [PM2.5], NO2 and O3 concentration) and a series of covariates were from various source. …”
Get full text

Age, frequency, and strategy optimization for organized colorectal cancer screening: a decision analysis conducted in China for the years 2023–2038 by Zixing Wang, Wei Han, Ran Fei, Yaoda Hu, Fang Xue, Wentao Gu, Cuihong Yang, Yubing Shen, Luwen Zhang, Jingmei Jiang

“…Abstract Background The colorectal cancer mortality rate in China has exceeded that in many developing countries and is expected to further increase owing to multiple factors, including the aging population. …”
Get full text

Robotic total knee arthroplasty safely reduces length of stay in an Asian public healthcare system by Kai C. A. Chan, Amy Cheung, Ping-Keung Chan, Michelle H. Luk, Kwong Y. Chiu, Henry Fu

“…Secondary outcomes were: 1) mean length of stay (LOS); 2) 30-day emergency department (ED) attendance rate; 3) 90-day ED attendance rate; 4) 90-day reoperation rate; 5) 90-day mortality rate; and 6) surgical time. Results: A total of 8,492 knees from 7,746 patients were included in the study. …”
Get full text

Associations of healthy lifestyle and family income to poverty ratio with all-cause mortality among people with prediabetes and diabetes: a prospective cohort study by Zhu Li, Lin Zhou, Yongshi Wu, Tao Ding, Yuxin Gan, Xiang Fan

“…During a mean follow-up of 92 months, participants with prediabetes or diabetes were also likely to have a higher mortality rate, respectively 583 (8.3%) and 263 (12.7%). …”
Get full text

STING modulates HBV-related acute-on-chronic liver failure by mediating autophagy and macrophage polarization by Hao Zhang, Teng Liang, Wanlu Duan, Futing Liu, LiPing Li, Qian Liu, Jianfei Li, Qiyin Zong, Lei Jin, Qin Wang, Qiang Zhou

“…Background & Aims: HBV-related acute-on-chronic liver failure (HBV-ACLF) is a severe acute liver injury secondary to HBV-related chronic liver disease (with or without cirrhosis) and is characterized by a high short-term mortality rate. Presently, there is a paucity of experimental models that specifically focus on HBV-ACLF based on chronic hepatitis B. …”
Get full text

Clinical course, management and outcomes of COVID-19 in HIV-infected renal transplant recipients: A case series by L Bertels, K Manning, A Redd, T du Toit, Z Barday, E Muller

“…In our case series, ~10% of the HIV‐positive‐to‐HIV‐positive transplant recipients died of COVID‐19 pneumonia. This mortality rate appears higher than figures reported in other transplant cohorts. …”
Get full text

Analysis of Prognostis Factors and Effect of Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease by Yiming XU, Honghua SHEN, Jingbo DU, Lei REN

“…On the contrary, the cumulative risk of COPD patients undergoing high strength aerobic exercise intervention was lower than COPD patients undergoing middle strength aerobic exercise intervention, and the cumulative risk of COPD patients undergoing low strength aerobic exercise intervention was the most.Conclusion:The worse the pulmonary function, the higher the BODE index, and the more times of acute exacerbations, the higher the mortality rate of COPD patients. In addition, aerobic exercise can improve the survival of COPD with chronic obstructive pulmonary disease within two years. …”
Get full text

Identification of early prediction biomarkers of severity in patients with severe fever with thrombocytopenia syndrome based on plasma proteomics by Qian Zhang, Qian Zhang, Zhengyi Jiang, Nan Jiang, Luchen Shi, Jiaying Zhao, Jie Zhao, Jie Zhao, Ke Ouyang, Ke Ouyang, Huaying Huang, Huaying Huang, Yaqin Zhang, Yan Dai, Nannan Hu, Ping Shi, Yaping Han, Ke Jin, Jun Li

“…Given its rapid disease progression and high mortality rate, early warning is crucial in improving the outcomes, However, to date, relevant comprehensive predictors or an effective prediction model are still poorly explored.MethodsA plasma proteomic profile was performed at early stages in patients with SFTS. …”
Get full text

Impact of Preoperative and Intraoperative Factors on Postoperative Outcomes in Patients with Colorectal Cancer: A 10-Year Retrospective Study by Lucian Flavius Herlo, Ioana Golu, Alexandra Herlo, Claudia Raluca Balasa Virzob, Ionescu Alin, Stela Iurciuc, Ionut Eduard Iordache, Luana Alexandrescu, Doina Ecaterina Tofolean, Raluca Dumache

“…Results: Postoperative complications occurred in 28.5% of patients, and the 30-day mortality rate was 5.2%. Preoperative factors such as elevated C-reactive protein (CRP) levels (<i>p</i> < 0.001), low albumin levels (<i>p</i> = 0.003), a high American Society of Anesthesiologists (ASA) score (<i>p</i> < 0.001), and presence of comorbidities like diabetes and hypertension (<i>p</i> = 0.005) were significantly associated with increased postoperative complications. …”
Get full text

Metabolic resistance to pyrethroids with possible involvement of non-coding ribonucleic acids in Anopheles funestus, the major malaria vector in western Kenya by Isaiah Debrah, Daibin Zhong, Maxwell G. Machani, Godfrey Nattoh, Kevin O. Ochwedo, Collins M. Morang’a, Ming-Chieh Lee, Linda E. Amoah, Andrew K. Githeko, Yaw A. Afrane, Guiyun Yan

“…Results Pyrethroid resistance was observed in all sites with an average mortality rate (MR) of 57.6%. Port Victoria had the highest level of pyrethroid resistance to permethrin (MR = 53%) and deltamethrin (MR = 11%. …”
Get full text

Immunohistochemical Expression of p53 Gene and Clinicopathological Assessment of Low-grade Serous Ovarian Cancer and High-grade Serous Ovarian Cancer: A Cohort Study by Geeta Bazard, Minakshi Vashist, Sunita Singh, Gulshan Rohilla, Nidhi Paliwal

“…However, by understanding genetic predisposition of ovarian tumour preventive steps as well as planning of early treatment can reduce the mortality rate.…”
Get full text

The history of childbirth: Women and doctors in the lying-in hospital of Göttingen University, eighteenth – nineteenth century by Jürgen Schlumbohm

“…Throughout Europe, the maternal mortality rate was higher in hospitals than for normal home deliveries attended by midwives. …”
Get full text

Prediction Models of Severity in Acute Biliary Pancreatitis by Iulia Ratiu, Renata Bende, Camelia Nica, Oana Budii, Calin Burciu, Andreea Barbulescu, Tudor Moga, Bogdan Miutescu, Roxana Sirli, Mirela Danila, Alina Popescu, Felix Bende

“…While the overall mortality rate of acute pancreatitis is relatively low, ranging between 3 and 5% in most cases, severe forms can result in significantly higher morbidity and mortality. …”
Get full text

Multidrug-Resistant <i>Acinetobacter baumannii</i>: Risk Factors for Mortality in a Tertiary Care Teaching Hospital by Kristina Černiauskienė, Astra Vitkauskienė

“…Conclusions: MDR <i>A. baumannii</i> infections pose a significant threat to human health not only due to multidrug resistance but also due to high mortality. The mortality rate of patients with MDR <i>A. baumannii</i> infection was high and was associated with age, invasive mechanical ventilation, the duration of effective antibiotic treatment, no co-infection, and combination therapy. …”
Get full text

Machine learning derivation of two cardiac arrest subphenotypes with distinct responses to treatment by Weidong Zhang, Chenxi Wu, Peifeng Ni, Sheng Zhang, Hongwei Zhang, Ying Zhu, Wei Hu, Mengyuan Diao

“…Furthermore, in-hospital and 28-day mortality rates of patients across different CA subphenotypes were assessed using multivariate logistic and Cox regression analysis. …”
Get full text

Brain-targeting drug delivery systems: The state of the art in treatment of glioblastoma by Bo Sun, Rong Li, Ning Ji, Han Liu, Hongxiang Wang, Chao Chen, Long Bai, Jiacan Su, Juxiang Chen

“…Glioblastoma (GBM) is the most prevalent primary malignant brain tumor, characterized by a high mortality rate and a poor prognosis. The blood-brain barrier (BBB) and the blood-tumor barrier (BTB) present significant obstacles to the efficacy of tumor-targeted pharmacotherapy, thereby impeding the therapeutic potential of numerous candidate drugs. …”
Get full text

Aspergillus identification through bronchoscope in intensive care unit – a retrospective, databased cohort study by Hsin-I Cheng, Chun-Yu Lin, Chun-Yu Lin, Horng-Chyuan Lin, Horng-Chyuan Lin, Horng-Chyuan Lin, Shu-Min Lin, Shu-Min Lin, Shu-Min Lin, Shu-Min Lin, Meng-Heng Hsieh, Meng-Heng Hsieh, Yueh-Fu Fang, Yueh-Fu Fang, Po-Jui Chang, Po-Jui Chang, Wei-Syun Hung, Ko Cheng, Chung−Chi Huang, Chung−Chi Huang

“…Patients with Aspergillus isolates were more likely to have a recent influenza infection, concurrent bacterial sepsis, and a cavitation and to die in hospital (in-hospital mortality rate 58.9% vs. 48.57%, P = 0.016).DiscussionIdentifying Aspergillus through bronchoscopy in the ICU is associated with higher mortality rates than in patients who test negative for Aspergillus. …”
Get full text

Effectiveness of Noninvasive Positive Pressure Ventilation Combined with Enteral Nutrition in the Treatment of Patients with Combined Respiratory Failure after Lung Cancer Surgery... by Yongjun Zhang, Lanbo Liu, Dawei Li, Dongsheng Zhou

“…It can improve patients’ pulmonary function and blood gas index, correct patients’ hypoxia status and the patients’ nutritional level was significantly improved, which helped to reduce the mortality rate and improve the prognosis.…”
Get full text